临床相关性：Diagnosis/typing
A total of 150 records found
#22186
high Confidence
Subject:
Malignant_gastrointestinal_neuroectodermal_tumor
(Tumor diseases)
→
is_associated_with
→
Object:
EWSR1-CREB1_fusion
(Gene fusion)
Original: Malignant gastrointestinal neuroectodermal tumor (MGNET)#is associated with#EWSR1-ATF1/CREB1 fusions
#22185
high Confidence
Subject:
Malignant_gastrointestinal_neuroectodermal_tumor
(Tumor diseases)
→
is_associated_with
→
Object:
EWSR1-ATF1_fusion
(Gene fusion)
Original: Malignant gastrointestinal neuroectodermal tumor (MGNET)#is associated with#EWSR1-ATF1/CREB1 fusions
#22128
high Confidence
Subject:
NPM1_mutation
(Gene mutation)
→
is_regarded_as
→
Object:
distinct_genetic_entity_in_WHO_classification
(Molecular typing)
Original: NPM1 mutation#is regarded as#a distinct genetic entity in the WHO classification of hematopoietic malignancies
#22104
high Confidence
Subject:
NOP16
(Ribosomal proteins)
→
is_upregulated_in
→
Object:
LIHC
(disease)
Original: Pan-cancer analysis#revealed#high NOP16 expression in 20 cancer types/ including LIHC
#21933
high Confidence
Subject:
keratin
(Structural proteins)
→
shows
→
Object:
intense_expression
(Protein expression level)
Original: immunohistochemical staining#demonstrates#intense expression of CD31/ CD34/ factor VIII related antigen/ and keratin
#21932
high Confidence
Subject:
factor_VIII_related_antigen
(Enzymes)
→
shows
→
Object:
intense_expression
(Protein expression level)
Original: immunohistochemical staining#demonstrates#intense expression of CD31/ CD34/ factor VIII related antigen/ and keratin
#21931
high Confidence
Subject:
CD34
(Receptor protein)
→
shows
→
Object:
intense_expression
(Protein expression level)
Original: immunohistochemical staining#demonstrates#intense expression of CD31/ CD34/ factor VIII related antigen/ and keratin
#21930
high Confidence
Subject:
CD31
(Receptor protein)
→
shows
→
Object:
intense_expression
(Protein expression level)
Original: immunohistochemical staining#demonstrates#intense expression of CD31/ CD34/ factor VIII related antigen/ and keratin
#21861
high Confidence
Subject:
ROS1
(Protein coding genes)
→
is_rearranged_in
→
Object:
lung_adenocarcinoma
(Solid Tumors)
Original: A young woman#was diagnosed with#ROS1-rearranged lung adenocarcinoma
#21702
high Confidence
Subject:
NUT_gene_rearrangement
(Gene rearrangement)
→
is_associated_with
→
Object:
midline_carcinoma
(Tumor)
Original: Midline carcinomas#are associated with#NUT gene rearrangement
#21362
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
actin
(protein)
Original: Tumor cells#were negative for#CD207/Langerin/ CKpan/ CD21/ HMB45/ ALK/ actin
#21361
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
ALK
(protein)
Original: Tumor cells#were negative for#CD207/Langerin/ CKpan/ CD21/ HMB45/ ALK/ actin
#21360
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
HMB45
(protein)
Original: Tumor cells#were negative for#CD207/Langerin/ CKpan/ CD21/ HMB45/ ALK/ actin
#21359
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
CD21
(protein)
Original: Tumor cells#were negative for#CD207/Langerin/ CKpan/ CD21/ HMB45/ ALK/ actin
#21358
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
CKpan
(protein)
Original: Tumor cells#were negative for#CD207/Langerin/ CKpan/ CD21/ HMB45/ ALK/ actin
#21357
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
CD207
(protein)
Original: Tumor cells#were negative for#CD207/Langerin/ CKpan/ CD21/ HMB45/ ALK/ actin
#21356
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CCND1
(protein)
Original: Tumor cells#were positive for#S-100/ CD1a/ CD68/ cyclin D1
#21355
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD68
(protein)
Original: Tumor cells#were positive for#S-100/ CD1a/ CD68/ cyclin D1
#21354
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD1A
(protein)
Original: Tumor cells#were positive for#S-100/ CD1a/ CD68/ cyclin D1
#21353
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
S100A1
(protein)
Original: Tumor cells#were positive for#S-100/ CD1a/ CD68/ cyclin D1
#21286
high Confidence
Subject:
epithelioid_sarcoma
(Tumor type)
→
associated_with
→
Object:
complete_loss_of_SMARCB1_expression
(Abnormal gene expression)
Original: pediatric tumors with complete loss of SMARCB1 expression#include#cribriform neuroepithelial tumor/ renal medullary carcinoma/ and epithelioid sarcoma
#21285
high Confidence
Subject:
renal_medullary_carcinoma
(Tumor type)
→
associated_with
→
Object:
complete_loss_of_SMARCB1_expression
(Abnormal gene expression)
Original: pediatric tumors with complete loss of SMARCB1 expression#include#cribriform neuroepithelial tumor/ renal medullary carcinoma/ and epithelioid sarcoma
#21284
high Confidence
Subject:
cribriform_neuroepithelial_tumor
(Tumor type)
→
associated_with
→
Object:
complete_loss_of_SMARCB1_expression
(Abnormal gene expression)
Original: pediatric tumors with complete loss of SMARCB1 expression#include#cribriform neuroepithelial tumor/ renal medullary carcinoma/ and epithelioid sarcoma
#21276
high Confidence
Subject:
small-cell_lung_carcinoma
(Tumor type)
→
belongs_to
→
Object:
neuroendocrine_group_of_lung_tumors
(Tumor classification)
Original: Small-cell lung carcinoma (SCLC)#belongs to#neuroendocrine group of lung tumors
#21144
high Confidence
Subject:
Primary_plasma_cell_leukemia
(disease)
→
is
→
Object:
rare_plasma_cell_malignancy
(Disease Type)
Original: Primary plasma cell leukemia#is#a rare and highly aggressive plasma cell malignancy
#20943
high Confidence
Subject:
S100B
(Protein coding genes)
→
shows_positive_staining_with
→
Object:
S-100
(protein)
Original: these cells#stained positively with#S-100
#20853
high Confidence
Subject:
granular_cell_tumors
(Tumor type)
→
are_divided_into
→
Object:
malignant_category
(Tumor grade)
Original: granular cell tumors#are divided into#benign/ atypical/ and malignant categories
#20852
high Confidence
Subject:
granular_cell_tumors
(Tumor type)
→
are_divided_into
→
Object:
atypical_category
(Tumor grade)
Original: granular cell tumors#are divided into#benign/ atypical/ and malignant categories
#20851
high Confidence
Subject:
granular_cell_tumors
(Tumor type)
→
are_divided_into
→
Object:
benign_category
(Tumor grade)
Original: granular cell tumors#are divided into#benign/ atypical/ and malignant categories
#20849
high Confidence
Subject:
breast_carcinoma_cases
(Cancer patients)
→
are_categorized_into
→
Object:
basal_like
(Molecular subtypes)
Original: breast carcinoma cases#are categorized into#luminal A/ luminal B/ null subtypes/ HER2-overexpressing and basal-like
#20848
high Confidence
Subject:
breast_carcinoma_cases
(Cancer patients)
→
are_categorized_into
→
Object:
HER2_overexpressing
(Molecular subtypes)
Original: breast carcinoma cases#are categorized into#luminal A/ luminal B/ null subtypes/ HER2-overexpressing and basal-like
#20847
high Confidence
Subject:
breast_carcinoma_cases
(Cancer patients)
→
are_categorized_into
→
Object:
luminal_B
(Molecular subtypes)
Original: breast carcinoma cases#are categorized into#luminal A/ luminal B/ null subtypes/ HER2-overexpressing and basal-like
#20846
high Confidence
Subject:
breast_carcinoma_cases
(Cancer patients)
→
are_categorized_into
→
Object:
luminal_A
(Molecular subtypes)
Original: breast carcinoma cases#are categorized into#luminal A/ luminal B/ null subtypes/ HER2-overexpressing and basal-like
#20745
high Confidence
Subject:
SMARCB1-deficient_tumors
(Tumor tissue)
→
includes
→
Object:
malignant_rhabdoid_tumor
(Tumor tissue)
Original: SMARCB1-deficient tumors#include#epithelioid sarcomas and malignant rhabdoid tumors
#20744
high Confidence
Subject:
SMARCB1-deficient_tumors
(Tumor tissue)
→
includes
→
Object:
epithelioid_sarcoma
(Tumor tissue)
Original: SMARCB1-deficient tumors#include#epithelioid sarcomas and malignant rhabdoid tumors
#20510
high Confidence
Subject:
PIK3CA
(Protein coding genes)
→
is_highly_expressed_in
→
Object:
endometrial_cancer_cells
(Tumor cells)
Original: p110α#is highly expressed in#endometrial cancer (EC) cell lines and primary tumors
#20363
high Confidence
Subject:
NOP16_expression
(Gene expression)
→
was_examined_using
→
Object:
GEO_database
(Bioinformatics databases)
Original: NOP16 expression in LIHC#was examined using#various analyses/ including TCGA and GEO databases
#20362
high Confidence
Subject:
NOP16_expression
(Gene expression)
→
was_examined_using
→
Object:
TCGA_database
(Bioinformatics databases)
Original: NOP16 expression in LIHC#was examined using#various analyses/ including TCGA and GEO databases
#20285
high Confidence
Subject:
Silver_staining_of_AgNORs
(Dyeing technology)
→
is_used_as
→
Object:
Marker_of_malignancy
(Molecular markers)
Original: Silver staining of AgNORs#is widely used as#a marker of malignancy in tumor pathology
#19966
middle Confidence
Subject:
Ag-NORs
(Nucleolar Organizing Region-associated Protein)
→
is_useful_for
→
Object:
estimating_proliferating_potential
(Cell proliferation ability)
Original: Ag-NORs#is#useful as a tool for estimating proliferating potential of various brain tumors
#19959
middle Confidence
Subject:
sinonasal_carcinomas
(Tumor type)
→
associated_with
→
Object:
variable_loss_of_SMARCB1_expression
(Abnormal gene expression)
Original: tumors with variable loss of SMARCB1 expression#include#epithelioid malignant peripheral nerve sheath tumor/ schwannomas in schwannomatosis/ chordomas/ myoepithelial carcinomas/ and sinonasal carcinomas
#19958
middle Confidence
Subject:
myoepithelial_carcinomas
(Tumor type)
→
associated_with
→
Object:
variable_loss_of_SMARCB1_expression
(Abnormal gene expression)
Original: tumors with variable loss of SMARCB1 expression#include#epithelioid malignant peripheral nerve sheath tumor/ schwannomas in schwannomatosis/ chordomas/ myoepithelial carcinomas/ and sinonasal carcinomas
#19957
middle Confidence
Subject:
chordomas
(Tumor type)
→
associated_with
→
Object:
variable_loss_of_SMARCB1_expression
(Abnormal gene expression)
Original: tumors with variable loss of SMARCB1 expression#include#epithelioid malignant peripheral nerve sheath tumor/ schwannomas in schwannomatosis/ chordomas/ myoepithelial carcinomas/ and sinonasal carcinomas
#19956
middle Confidence
Subject:
schwannomas_in_schwannomatosis
(Tumor type)
→
associated_with
→
Object:
variable_loss_of_SMARCB1_expression
(Abnormal gene expression)
Original: tumors with variable loss of SMARCB1 expression#include#epithelioid malignant peripheral nerve sheath tumor/ schwannomas in schwannomatosis/ chordomas/ myoepithelial carcinomas/ and sinonasal carcinomas
#19955
middle Confidence
Subject:
epithelioid_malignant_peripheral_nerve_sheath_tumor
(Tumor type)
→
associated_with
→
Object:
variable_loss_of_SMARCB1_expression
(Abnormal gene expression)
Original: tumors with variable loss of SMARCB1 expression#include#epithelioid malignant peripheral nerve sheath tumor/ schwannomas in schwannomatosis/ chordomas/ myoepithelial carcinomas/ and sinonasal carcinomas
#19739
middle Confidence
Subject:
p53
(Tumor suppressor proteins)
→
is_associated_with
→
Object:
high_MIB-1_score
(Increased cell proliferation marker scores)
Original: p53 immunopositivity#is associated with#high AgNOR quantity and MIB-1 scores in MBC and bladder neoplasm
#19738
middle Confidence
Subject:
p53
(Tumor suppressor proteins)
→
is_associated_with
→
Object:
high_AgNOR_quantity
(Increased number of nucleolar organizer regions)
Original: p53 immunopositivity#is associated with#high AgNOR quantity and MIB-1 scores in MBC and bladder neoplasm
#19647
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
show
→
Object:
cytoplasmic_immunopositivity_for_vimentin
(Protein expression)
Original: Tumor cells#show#strong cytoplasmic immunopositivity for myoglobin and vimentin
#19646
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
show
→
Object:
cytoplasmic_immunopositivity_for_myoglobin
(Protein expression)
Original: Tumor cells#show#strong cytoplasmic immunopositivity for myoglobin and vimentin
#19642
middle Confidence
Subject:
CCS
(Tumor type)
→
shows
→
Object:
chromosomal_translocation_t(12;22)(q13;q12)
(Chromosomal mutations)
Original: CCS#shows#a distinct chromosomal translocation pattern t(12;22)(q13;q12)
#19555
middle Confidence
Subject:
Abnormal_cell_group
(Cell population)
→
does_not_express
→
Object:
cLambda
(Immunoglobulin light chain)
Original: Abnormal cell group#expressed#CD38/ CD138/ CD117/ cKappa/ partly CD20/ weak CD45/ not CD27/ CD19/ CD56/ CD200/ CD81/ cLambda
#19554
middle Confidence
Subject:
Abnormal_cell_group
(Cell population)
→
does_not_express
→
Object:
CD81
(Cell surface molecules)
Original: Abnormal cell group#expressed#CD38/ CD138/ CD117/ cKappa/ partly CD20/ weak CD45/ not CD27/ CD19/ CD56/ CD200/ CD81/ cLambda
#19553
middle Confidence
Subject:
Abnormal_cell_group
(Cell population)
→
does_not_express
→
Object:
CD200
(Cell surface molecules)
Original: Abnormal cell group#expressed#CD38/ CD138/ CD117/ cKappa/ partly CD20/ weak CD45/ not CD27/ CD19/ CD56/ CD200/ CD81/ cLambda
#19552
middle Confidence
Subject:
Abnormal_cell_group
(Cell population)
→
does_not_express
→
Object:
CD56
(Cell surface molecules)
Original: Abnormal cell group#expressed#CD38/ CD138/ CD117/ cKappa/ partly CD20/ weak CD45/ not CD27/ CD19/ CD56/ CD200/ CD81/ cLambda
#19551
middle Confidence
Subject:
Abnormal_cell_group
(Cell population)
→
does_not_express
→
Object:
CD19
(Cell surface molecules)
Original: Abnormal cell group#expressed#CD38/ CD138/ CD117/ cKappa/ partly CD20/ weak CD45/ not CD27/ CD19/ CD56/ CD200/ CD81/ cLambda
#19550
middle Confidence
Subject:
Abnormal_cell_group
(Cell population)
→
does_not_express
→
Object:
CD27
(Cell surface molecules)
Original: Abnormal cell group#expressed#CD38/ CD138/ CD117/ cKappa/ partly CD20/ weak CD45/ not CD27/ CD19/ CD56/ CD200/ CD81/ cLambda
#19549
middle Confidence
Subject:
Abnormal_cell_group
(Cell population)
→
weakly_expresses
→
Object:
CD45
(Cell surface molecules)
Original: Abnormal cell group#expressed#CD38/ CD138/ CD117/ cKappa/ partly CD20/ weak CD45/ not CD27/ CD19/ CD56/ CD200/ CD81/ cLambda
#19548
middle Confidence
Subject:
Abnormal_cell_group
(Cell population)
→
partly_expresses
→
Object:
CD20
(Cell surface molecules)
Original: Abnormal cell group#expressed#CD38/ CD138/ CD117/ cKappa/ partly CD20/ weak CD45/ not CD27/ CD19/ CD56/ CD200/ CD81/ cLambda
#19547
middle Confidence
Subject:
Abnormal_cell_group
(Cell population)
→
expresses
→
Object:
cKappa
(Immunoglobulin light chain)
Original: Abnormal cell group#expressed#CD38/ CD138/ CD117/ cKappa/ partly CD20/ weak CD45/ not CD27/ CD19/ CD56/ CD200/ CD81/ cLambda
#19546
middle Confidence
Subject:
Abnormal_cell_group
(Cell population)
→
expresses
→
Object:
CD117
(Cell surface molecules)
Original: Abnormal cell group#expressed#CD38/ CD138/ CD117/ cKappa/ partly CD20/ weak CD45/ not CD27/ CD19/ CD56/ CD200/ CD81/ cLambda
#19545
middle Confidence
Subject:
Abnormal_cell_group
(Cell population)
→
expresses
→
Object:
CD138
(Cell surface molecules)
Original: Abnormal cell group#expressed#CD38/ CD138/ CD117/ cKappa/ partly CD20/ weak CD45/ not CD27/ CD19/ CD56/ CD200/ CD81/ cLambda
#19544
middle Confidence
Subject:
Abnormal_cell_group
(Cell population)
→
expresses
→
Object:
CD38
(Cell surface molecules)
Original: Abnormal cell group#expressed#CD38/ CD138/ CD117/ cKappa/ partly CD20/ weak CD45/ not CD27/ CD19/ CD56/ CD200/ CD81/ cLambda
#19512
middle Confidence
Subject:
histologic grade
(Histological grading)
→
correlates_positively_with
→
Object:
Cytologic grade
(Cytological grading)
Original: histologic grade#correlated positively with#cytologic grade
#19499
middle Confidence
Subject:
c-erbB2_oncoprotein
(Receptor tyrosine kinase protein)
→
shows_positive_immunoperoxidase_staining
→
Object:
immunoperoxidase_staining
(Protein expression detection)
Original: positive immunoperoxidase staining#was observed#for c-erb B2 oncoprotein
#19372
middle Confidence
Subject:
morphologic_features
(Morphological characteristics)
→
are_associated_with
→
Object:
BLBC
(Molecular subtypes)
Original: morphologic features#are associated with#BLBC/ including vesicular unclear chromatin and nucleolus
#19371
middle Confidence
Subject:
breast_carcinoma_cases
(Cancer patients)
→
are_categorized_into
→
Object:
null_subtypes
(Molecular subtypes)
Original: breast carcinoma cases#are categorized into#luminal A/ luminal B/ null subtypes/ HER2-overexpressing and basal-like
#19192
middle Confidence
Subject:
Ki-67_antigen
(Ribosome-associated proteins)
→
accumulates_in
→
Object:
heterochromatic_region_of_interphase_cells
(Cellular substructure)
Original: Ki-67 antigen#accumulates in#nucleolar and heterochromatic regions of interphase cells
#19191
middle Confidence
Subject:
Ki-67_antigen
(Ribosome-associated proteins)
→
accumulates_in
→
Object:
nucleolar_region
(Cellular substructure)
Original: Ki-67 antigen#accumulates in#nucleolar and heterochromatic regions of interphase cells
#18942
middle Confidence
Subject:
proliferating_cell_nuclear_antigen
(Proliferation-related proteins)
→
shows
→
Object:
higher_proliferating_cell_fraction
(Cell proliferation markers)
Original: proliferating cell nuclear antigen#shows#higher proliferating cell fraction in atypical and malignant meningiomas compared to benign meningiomas
#18597
middle Confidence
Subject:
AgNOR_count
(Molecular markers)
→
is_higher_in
→
Object:
Breast_carcinomas
(Tumor diseases)
Original: AgNOR count#was significantly higher in#breast carcinomas compared to benign breast diseases
#18586
middle Confidence
Subject:
MYC
(Transcription Factors)
→
correlates_with
→
Object:
MIB-1_score
(Cell proliferation marker scoring)
Original: Expression of p53/ c-erbB-2/ bcl-2/ and c-myc proteins#correlates with#AgNOR quantity and MIB-1 scores
#18585
middle Confidence
Subject:
BCL2
(Anti-apoptotic proteins)
→
correlates_with
→
Object:
MIB-1_score
(Cell proliferation marker scoring)
Original: Expression of p53/ c-erbB-2/ bcl-2/ and c-myc proteins#correlates with#AgNOR quantity and MIB-1 scores
#18584
middle Confidence
Subject:
ERBB2
(Receptor tyrosine kinases)
→
correlates_with
→
Object:
MIB-1_score
(Cell proliferation marker scoring)
Original: Expression of p53/ c-erbB-2/ bcl-2/ and c-myc proteins#correlates with#AgNOR quantity and MIB-1 scores
#18583
middle Confidence
Subject:
TP53
(Tumor suppressor proteins)
→
correlates_with
→
Object:
MIB-1_score
(Cell proliferation marker scoring)
Original: Expression of p53/ c-erbB-2/ bcl-2/ and c-myc proteins#correlates with#AgNOR quantity and MIB-1 scores
#18582
middle Confidence
Subject:
MYC
(Transcription Factors)
→
correlates_with
→
Object:
AgNOR_quantity
(Nucleolar organizer region number)
Original: Expression of p53/ c-erbB-2/ bcl-2/ and c-myc proteins#correlates with#AgNOR quantity and MIB-1 scores
#18581
middle Confidence
Subject:
BCL2
(Anti-apoptotic proteins)
→
correlates_with
→
Object:
AgNOR_quantity
(Nucleolar organizer region number)
Original: Expression of p53/ c-erbB-2/ bcl-2/ and c-myc proteins#correlates with#AgNOR quantity and MIB-1 scores
#18580
middle Confidence
Subject:
ERBB2
(Receptor tyrosine kinases)
→
correlates_with
→
Object:
AgNOR_quantity
(Nucleolar organizer region number)
Original: Expression of p53/ c-erbB-2/ bcl-2/ and c-myc proteins#correlates with#AgNOR quantity and MIB-1 scores
#18579
middle Confidence
Subject:
TP53
(Tumor suppressor proteins)
→
correlates_with
→
Object:
AgNOR_quantity
(Nucleolar organizer region number)
Original: Expression of p53/ c-erbB-2/ bcl-2/ and c-myc proteins#correlates with#AgNOR quantity and MIB-1 scores
#18576
middle Confidence
Subject:
AgNORs_frequency
(Frequency of silver staining associated with the nucleolar organizer region)
→
is_lower_in
→
Object:
benign_neoplastic_cells
(Benign tumor cells)
Original: frequency of AgNORs#is higher in#malignant cells than normal or benign neoplastic cells
#18575
middle Confidence
Subject:
AgNORs_frequency
(Frequency of silver staining associated with the nucleolar organizer region)
→
is_lower_in
→
Object:
normal_cells
(Normal cells)
Original: frequency of AgNORs#is higher in#malignant cells than normal or benign neoplastic cells
#18574
middle Confidence
Subject:
AgNORs_frequency
(Frequency of silver staining associated with the nucleolar organizer region)
→
is_higher_in
→
Object:
malignant_cells
(Tumor cells)
Original: frequency of AgNORs#is higher in#malignant cells than normal or benign neoplastic cells
#18488
middle Confidence
Subject:
Indeterminate_dendritic_cell_tumor
(disease)
→
has
→
Object:
clinicopathologic_features
(Clinicopathological characteristics)
Original: Indeterminate dendritic cell tumor (IDCT)#has#clinicopathologic features
#17872
middle Confidence
Subject:
BCL6
(protein)
→
expressed_in
→
Object:
tumor_cells
(Tumor cells)
Original: Tumor cells#expressed#CD45/ CD20/ BCl-6
#17871
middle Confidence
Subject:
CD20
(protein)
→
expressed_in
→
Object:
tumor_cells
(Tumor cells)
Original: Tumor cells#expressed#CD45/ CD20/ BCl-6
#17870
middle Confidence
Subject:
CD45
(protein)
→
expressed_in
→
Object:
tumor_cells
(Tumor cells)
Original: Tumor cells#expressed#CD45/ CD20/ BCl-6
#17423
middle Confidence
Subject:
gastric_carcinoma
(Tumor)
→
showed
→
Object:
vimentin_positivity
(Molecular markers)
Original: gastric carcinoma#showed#positivity for vimentin
#17313
middle Confidence
Subject:
tumor
(Tumor)
→
is_classified_by
→
Object:
growth_pattern
(Growth pattern)
Original: Tumor#is classified by#cellular differentiation and growth pattern
#17312
middle Confidence
Subject:
tumor
(Tumor)
→
is_classified_by
→
Object:
cellular_differentiation
(Cell differentiation state)
Original: Tumor#is classified by#cellular differentiation and growth pattern
#16671
middle Confidence
Subject:
nucleolar_organizer_regions
(Nuclear structure)
→
analyze
→
Object:
cell_proliferative_activity
(Cell proliferation markers)
Original: nucleolar organizer regions (AgNORs)#analyze#cell proliferative activity in myeloma cells
#16576
middle Confidence
Subject:
AgNOR_enumeration
(AgNOR Count)
→
is_investigated_in
→
Object:
testicular_tumors
(Tumor type)
Original: Enumeration and image analysis of AgNORs#are investigated in#testicular tumors and normal tissues
#16575
middle Confidence
Subject:
AgNOR_number
(Nucleoli with silver staining in the nucleus)
→
is_investigated_in
→
Object:
thymic_carcinomas
(Tumor type)
Original: AgNOR number#is investigated in#thymomas and thymic carcinomas
#16574
middle Confidence
Subject:
AgNOR_number
(Nucleoli with silver staining in the nucleus)
→
is_investigated_in
→
Object:
thymomas
(Tumor type)
Original: AgNOR number#is investigated in#thymomas and thymic carcinomas
#16292
middle Confidence
Subject:
cells
(Cell population)
→
expresses
→
Object:
WT1
(Transcription Factors)
Original: cells#express#CD31/ CD34/ factor VIII/ Fli-1/ vimentin/ smooth muscle actin/ and WT-1
#16291
middle Confidence
Subject:
cells
(Cell population)
→
expresses
→
Object:
smooth_muscle_actin
(Cytoskeletal proteins)
Original: cells#express#CD31/ CD34/ factor VIII/ Fli-1/ vimentin/ smooth muscle actin/ and WT-1
#16290
middle Confidence
Subject:
cells
(Cell population)
→
expresses
→
Object:
vimentin
(Cytoskeletal proteins)
Original: cells#express#CD31/ CD34/ factor VIII/ Fli-1/ vimentin/ smooth muscle actin/ and WT-1
#16289
middle Confidence
Subject:
cells
(Cell population)
→
expresses
→
Object:
Fli-1
(Transcription Factors)
Original: cells#express#CD31/ CD34/ factor VIII/ Fli-1/ vimentin/ smooth muscle actin/ and WT-1
#16288
middle Confidence
Subject:
cells
(Cell population)
→
expresses
→
Object:
factor_VIII
(Coagulation factors)
Original: cells#express#CD31/ CD34/ factor VIII/ Fli-1/ vimentin/ smooth muscle actin/ and WT-1
#16287
middle Confidence
Subject:
cells
(Cell population)
→
expresses
→
Object:
CD34
(Cell surface molecules)
Original: cells#express#CD31/ CD34/ factor VIII/ Fli-1/ vimentin/ smooth muscle actin/ and WT-1
#16286
middle Confidence
Subject:
cells
(Cell population)
→
expresses
→
Object:
CD31
(Cell surface molecules)
Original: cells#express#CD31/ CD34/ factor VIII/ Fli-1/ vimentin/ smooth muscle actin/ and WT-1
#16127
middle Confidence
Subject:
mast_cell_sarcoma
(Tumor)
→
is_associated_with
→
Object:
neuroendocrine_marker_expression
(Molecular phenotype)
Original: Mast cell sarcoma#is associated with#neuroendocrine marker expression
#15878
middle Confidence
Subject:
histologic_type
(Histological type)
→
is_related_to
→
Object:
number_of_nucleolar_organizer_regions
(NOR)
Original: Histologic type#is related to#number of nucleolar organizer regions
#15871
middle Confidence
Subject:
AgNOR_count
(Molecular markers)
→
is_lower_in
→
Object:
Benign_breast_diseases
(Benign diseases)
Original: AgNOR count#was significantly higher in#breast carcinomas compared to benign breast diseases
#15842
middle Confidence
Subject:
AgNORs
(Nucleolar organizer region-related structures)
→
are_higher_in
→
Object:
cagA_positive_specimens
(Pathological specimens)
Original: Counts of AgNORs#are higher in#H. pylori positive and cagA positive specimens
#15841
middle Confidence
Subject:
AgNORs
(Nucleolar organizer region-related structures)
→
are_higher_in
→
Object:
H._pylori_positive_specimens
(Pathological specimens)
Original: Counts of AgNORs#are higher in#H. pylori positive and cagA positive specimens
#15839
middle Confidence
Subject:
AgNOR_count
(Nucleolar organizer region-related silver stain counts)
→
is_measured_in
→
Object:
breast_carcinoma
(Breast cancer)
Original: bromodeoxyuridine labeling index/ Ki-67 score/ and Ag-NOR count#are measured in#breast carcinomas
#15838
middle Confidence
Subject:
Ki-67_score
(Proliferation markers)
→
is_measured_in
→
Object:
breast_carcinoma
(Breast cancer)
Original: bromodeoxyuridine labeling index/ Ki-67 score/ and Ag-NOR count#are measured in#breast carcinomas
#15837
middle Confidence
Subject:
bromodeoxyuridine_labeling_index
(Proliferation markers)
→
is_measured_in
→
Object:
breast_carcinoma
(Breast cancer)
Original: bromodeoxyuridine labeling index/ Ki-67 score/ and Ag-NOR count#are measured in#breast carcinomas
#15836
middle Confidence
Subject:
proliferative_potential_of_neoplastic_cells
(Tumor cell proliferation potential)
→
is_investigated_with
→
Object:
GFAP_staining
(Immunohistochemistry)
Original: proliferative potential of neoplastic cells#is investigated with#AgNOR and GFAP staining
#15835
middle Confidence
Subject:
proliferative_potential_of_neoplastic_cells
(Tumor cell proliferation potential)
→
is_investigated_with
→
Object:
AgNOR_staining
(Histochemical techniques)
Original: proliferative potential of neoplastic cells#is investigated with#AgNOR and GFAP staining
#15745
middle Confidence
Subject:
Ag-NORs_per_nuclei
(Nucleolar Organizing Region-associated Protein)
→
showed
→
Object:
recurrent_meningiomas
(Tumor tissue)
Original: Ag-NORs per nuclei#showed#significant differences among glioblastomas/ pleomorphic xanthoastrocytoma/ benign astrocytoma/ nonrecurrent meningiomas/ and recurrent meningiomas
#15744
middle Confidence
Subject:
Ag-NORs_per_nuclei
(Nucleolar Organizing Region-associated Protein)
→
showed
→
Object:
nonrecurrent_meningiomas
(Tumor tissue)
Original: Ag-NORs per nuclei#showed#significant differences among glioblastomas/ pleomorphic xanthoastrocytoma/ benign astrocytoma/ nonrecurrent meningiomas/ and recurrent meningiomas
#15743
middle Confidence
Subject:
Ag-NORs_per_nuclei
(Nucleolar Organizing Region-associated Protein)
→
showed
→
Object:
benign_astrocytoma
(Tumor tissue)
Original: Ag-NORs per nuclei#showed#significant differences among glioblastomas/ pleomorphic xanthoastrocytoma/ benign astrocytoma/ nonrecurrent meningiomas/ and recurrent meningiomas
#15742
middle Confidence
Subject:
Ag-NORs_per_nuclei
(Nucleolar Organizing Region-associated Protein)
→
showed
→
Object:
pleomorphic_xanthoastrocytoma
(Tumor tissue)
Original: Ag-NORs per nuclei#showed#significant differences among glioblastomas/ pleomorphic xanthoastrocytoma/ benign astrocytoma/ nonrecurrent meningiomas/ and recurrent meningiomas
#15741
middle Confidence
Subject:
Ag-NORs_per_nuclei
(Nucleolar Organizing Region-associated Protein)
→
showed
→
Object:
glioblastoma
(Tumor tissue)
Original: Ag-NORs per nuclei#showed#significant differences among glioblastomas/ pleomorphic xanthoastrocytoma/ benign astrocytoma/ nonrecurrent meningiomas/ and recurrent meningiomas
#14621
middle Confidence
Subject:
p16_protein_nuclear_accumulation
(Protein expression characteristics)
→
was_examined_in
→
Object:
each_component
(Tissue composition)
Original: Ki-67 labeling index and nuclear accumulation of p53 and p16 protein#were examined in#each component
#14620
middle Confidence
Subject:
p53_nuclear_accumulation
(Protein expression characteristics)
→
was_examined_in
→
Object:
each_component
(Tissue composition)
Original: Ki-67 labeling index and nuclear accumulation of p53 and p16 protein#were examined in#each component
#14619
middle Confidence
Subject:
Ki-67_labeling_index
(Proliferation markers)
→
was_examined_in
→
Object:
each_component
(Tissue composition)
Original: Ki-67 labeling index and nuclear accumulation of p53 and p16 protein#were examined in#each component
#13914
middle Confidence
Subject:
tumor
(Tumor tissue)
→
is_characterized_by
→
Object:
rhabdoid_cells
(Cell morphology)
Original: tumor#is characterized by#rhabdoid cells with prominent nucleoli and glassy eosinophilic cytoplasm
#13408
middle Confidence
Subject:
findings_in_LBC-S
(Cytological findings)
→
were_compared_with
→
Object:
follicular_neoplasm
(Tumor type)
Original: Findings in LBC-S#were compared with#55 adenomatous or hyperplastic nodule (AN) and 21 follicular neoplasm (FN) cases
#13407
middle Confidence
Subject:
findings_in_LBC-S
(Cytological findings)
→
were_compared_with
→
Object:
hyperplastic_nodule
(Benign nodules)
Original: Findings in LBC-S#were compared with#55 adenomatous or hyperplastic nodule (AN) and 21 follicular neoplasm (FN) cases
#13406
middle Confidence
Subject:
findings_in_LBC-S
(Cytological findings)
→
were_compared_with
→
Object:
adenomatous_nodule
(Benign nodules)
Original: Findings in LBC-S#were compared with#55 adenomatous or hyperplastic nodule (AN) and 21 follicular neoplasm (FN) cases
#12505
middle Confidence
Subject:
RCC
(Tumor)
→
demonstrates
→
Object:
rhabdoid_features
(Pathological phenotype)
Original: RCC in this patient#demonstrated#sarcomatoid and rhabdoid features
#12504
middle Confidence
Subject:
RCC
(Tumor)
→
demonstrates
→
Object:
sarcomatoid_features
(Pathological phenotype)
Original: RCC in this patient#demonstrated#sarcomatoid and rhabdoid features
#11919
middle Confidence
Subject:
silver_staining_technique
(Staining method)
→
is_used_to_study
→
Object:
nucleolar_organizer_regions
(Nuclear structure)
Original: silver staining technique#is used to study#nucleolar organizer regions in meningiomas
#11673
middle Confidence
Subject:
apoptotic_index
(Cellular process indicators)
→
correlates_with
→
Object:
clinicopathological_parameters
(Clinicopathological characteristics)
Original: apoptotic index (AI)#correlates with#clinicopathological parameters
#11570
middle Confidence
Subject:
Xp11_neoplasm
(Tumor type)
→
shows
→
Object:
genetic_alterations
(Genetic variation)
Original: study#investigates#clinical/ histologic/ immunophenotypic features/ genetic alterations/ and prognosis of Xp11 neoplasm with melanocytic differentiation
#11235
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_reactive_to
→
Object:
MBI
(Cell surface antigens)
Original: tumor cells#were reactive#to leukocyte common antigen and MBI
#11234
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_reactive_to
→
Object:
leukocyte_common_antigen
(Cell surface antigens)
Original: tumor cells#were reactive#to leukocyte common antigen and MBI
#10173
middle Confidence
Subject:
patients
(patient)
→
presented_with
→
Object:
myasthenia_gravis
(Disease phenotype)
Original: patients#presented with#pure red cell aplasia and myasthenia gravis
#10172
middle Confidence
Subject:
patients
(patient)
→
presented_with
→
Object:
pure_red_cell_aplasia
(Disease phenotype)
Original: patients#presented with#pure red cell aplasia and myasthenia gravis
#10166
middle Confidence
Subject:
Xp11_neoplasm
(Tumor type)
→
shows
→
Object:
histologic_features
(Histological characteristics)
Original: study#investigates#clinical/ histologic/ immunophenotypic features/ genetic alterations/ and prognosis of Xp11 neoplasm with melanocytic differentiation
#10165
middle Confidence
Subject:
Xp11_neoplasm
(Tumor type)
→
shows
→
Object:
immunophenotypic_features
(Immunophenotype)
Original: study#investigates#clinical/ histologic/ immunophenotypic features/ genetic alterations/ and prognosis of Xp11 neoplasm with melanocytic differentiation
#10164
middle Confidence
Subject:
Xp11_neoplasm
(Tumor type)
→
shows
→
Object:
melanocytic_differentiation
(Differentiation phenotype)
Original: study#investigates#clinical/ histologic/ immunophenotypic features/ genetic alterations/ and prognosis of Xp11 neoplasm with melanocytic differentiation
#9806
middle Confidence
Subject:
AgNORs
(Nucleolar organizer region-related structures)
→
are_assessed_in
→
Object:
prostatic_adenocarcinoma_biopsy_specimens
(Prostate adenocarcinoma biopsy specimen)
Original: Silver stained nucleolar organizer regions (AgNORs)#are assessed in#prostatic adenocarcinoma biopsy specimens
#9794
middle Confidence
Subject:
proliferation_markers
(Cell proliferation markers)
→
are_analyzed_in
→
Object:
breast_carcinoma_cases
(Breast cancer cases)
Original: nuclear DNA content and proliferation markers#are analyzed in#breast carcinoma cases
#9793
middle Confidence
Subject:
nuclear_DNA_content
(Nuclear DNA content)
→
is_analyzed_in
→
Object:
breast_carcinoma_cases
(Breast cancer cases)
Original: nuclear DNA content and proliferation markers#are analyzed in#breast carcinoma cases
#9789
middle Confidence
Subject:
NM23
(Tumor suppressor genes)
→
are_studied_in
→
Object:
renal_cell_carcinoma
(Kidney cancer)
Original: AgNORs/ PCNA/ and nm23 oncogenes#are studied in#renal cell carcinomas and normal tissue
#9788
middle Confidence
Subject:
PCNA
(Proliferating cell nuclear antigen)
→
are_studied_in
→
Object:
renal_cell_carcinoma
(Kidney cancer)
Original: AgNORs/ PCNA/ and nm23 oncogenes#are studied in#renal cell carcinomas and normal tissue
#9787
middle Confidence
Subject:
AgNORs
(Nucleolar Organizing Region-associated Silver Stain)
→
are_studied_in
→
Object:
renal_cell_carcinoma
(Kidney cancer)
Original: AgNORs/ PCNA/ and nm23 oncogenes#are studied in#renal cell carcinomas and normal tissue
#7959
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_arranged_in
→
Object:
cords
(Organizational Structure)
Original: tumor cells#are arranged in#trabeculae and cords
#7958
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_arranged_in
→
Object:
trabeculae
(Organizational Structure)
Original: tumor cells#are arranged in#trabeculae and cords
#7957
middle Confidence
Subject:
granular_cell_tumors
(Tumor type)
→
are_characterized_by
→
Object:
uniform_nuclei
(Nuclear characteristics)
Original: granular cell tumors#are characterized by#abundant granular cytoplasm and uniform nuclei
#7956
middle Confidence
Subject:
granular_cell_tumors
(Tumor type)
→
are_characterized_by
→
Object:
abundant_granular_cytoplasm
(Cell morphology)
Original: granular cell tumors#are characterized by#abundant granular cytoplasm and uniform nuclei
#7955
middle Confidence
Subject:
tumors
(Tumor tissue)
→
show
→
Object:
primitive_round_or_ovoid_cells_with_active_mitosis_and_prominent_nucleoli
(Cell morphology)
Original: tumors#show#primitive round or ovoid cells with active mitosis and prominent nucleoli
#5609
middle Confidence
Subject:
endodermal_sinus_tumor
(Tumor diseases)
→
causes
→
Object:
peritoneal_effusion
(Disease phenotype)
Original: Three-year-old boy#presented with#peritoneal effusion due to an occult endodermal sinus tumor
#4637
middle Confidence
Subject:
18-year-old girl
(Patient characteristics)
→
presented_with
→
Object:
fever
(symptom)
Original: an 18-year-old girl#presented with#back pain/ cough/ dyspnea/ weakness/ and fever
#4636
middle Confidence
Subject:
18-year-old girl
(Patient characteristics)
→
presented_with
→
Object:
weakness
(symptom)
Original: an 18-year-old girl#presented with#back pain/ cough/ dyspnea/ weakness/ and fever
#4635
middle Confidence
Subject:
18-year-old girl
(Patient characteristics)
→
presented_with
→
Object:
dyspnea
(symptom)
Original: an 18-year-old girl#presented with#back pain/ cough/ dyspnea/ weakness/ and fever
#4634
middle Confidence
Subject:
18-year-old girl
(Patient characteristics)
→
presented_with
→
Object:
cough
(symptom)
Original: an 18-year-old girl#presented with#back pain/ cough/ dyspnea/ weakness/ and fever
#4633
middle Confidence
Subject:
18-year-old girl
(Patient characteristics)
→
presented_with
→
Object:
back pain
(symptom)
Original: an 18-year-old girl#presented with#back pain/ cough/ dyspnea/ weakness/ and fever