临床相关性：Epigenetic regulation
A total of 4 records found
#19203
middle Confidence
Subject:
SPC25_CpG_hypomethylation
(Epigenetic modification)
→
upregulates
→
Object:
SPC25_expression
(Gene expression)
Original: Hypomethylation of CpG sites in SPC25#elevates#SPC25 expression
#17068
middle Confidence
Subject:
BEND3
(Transcriptional regulatory proteins)
→
decreases
→
Object:
rDNA_promoter_DNA_methylation
(DNA methylation modification)
Original: Loss of BEND3#increases#H3K4 trimethylation and decreases rDNA promoter DNA methylation
#17067
middle Confidence
Subject:
BEND3
(Transcriptional regulatory proteins)
→
increases
→
Object:
H3K4_trimethylation
(Histone modification)
Original: Loss of BEND3#increases#H3K4 trimethylation and decreases rDNA promoter DNA methylation
#12489
middle Confidence
Subject:
BEND3
(Transcriptional regulatory proteins)
→
acts_together_with
→
Object:
NoRC
(Chromatin remodeling complexes)
Original: BEND3#acts together with#NoRC to establish rDNA silencing