临床相关性：Molecular typing
A total of 39 records found
#22182
high Confidence
Subject:
Rearrangement_of_polymorphous_adenocarcinoma-associated_genes
(Gene rearrangement)
→
was_identified_in
→
Object:
polymorphous_adenocarcinoma_cases
(Adenocarcinoma)
Original: Rearrangement of polymorphous adenocarcinoma-associated genes#was identified in#17 cases (47.2%)
#21683
high Confidence
Subject:
Tumor
(Tumor)
→
shows_profile
→
Object:
luminal B immunohistochemical profile
(Molecular subtypes)
Original: Tumors#show#a luminal B immunohistochemical profile in the majority of cases
#21135
high Confidence
Subject:
Polymorphous_adenocarcinoma-associated_genetic_alterations
(Genomic variation)
→
are_common_in
→
Object:
polymorphous_adenocarcinomas
(Adenocarcinoma)
Original: Polymorphous adenocarcinoma-associated genetic alterations#were disclosed as#common and specific findings in polymorphous adenocarcinomas
#20811
high Confidence
Subject:
NONO-TFE3_RCC
(Tumor subtype)
→
is_a_subtype_of
→
Object:
Xp11.2_translocation_renal_cell_carcinoma
(Tumor subtype)
Original: NONO-TFE3 RCC#is a subtype of#Xp11.2 translocation renal cell carcinoma
#20648
high Confidence
Subject:
Tumor
(Tumor)
→
is_enriched_with
→
Object:
HER2
(Receptor protein)
Original: One tumor#is enriched with#HER2
#20329
high Confidence
Subject:
high_nucleolus_score
(Pathological scoring)
→
correlates_with
→
Object:
HER2_status
(Molecular phenotype)
Original: High nucleolus score#correlates with#estrogen receptor negativity/ progesterone receptor negativity/ high Ki-67/ triple negative/ and HER-2 status
#20328
high Confidence
Subject:
high_nucleolus_score
(Pathological scoring)
→
correlates_with
→
Object:
triple_negative_status
(Molecular typing)
Original: High nucleolus score#correlates with#estrogen receptor negativity/ progesterone receptor negativity/ high Ki-67/ triple negative/ and HER-2 status
#20326
high Confidence
Subject:
high_nucleolus_score
(Pathological scoring)
→
correlates_with
→
Object:
progesterone_receptor_negativity
(Molecular phenotype)
Original: High nucleolus score#correlates with#estrogen receptor negativity/ progesterone receptor negativity/ high Ki-67/ triple negative/ and HER-2 status
#20325
high Confidence
Subject:
high_nucleolus_score
(Pathological scoring)
→
correlates_with
→
Object:
estrogen_receptor_negativity
(Molecular phenotype)
Original: High nucleolus score#correlates with#estrogen receptor negativity/ progesterone receptor negativity/ high Ki-67/ triple negative/ and HER-2 status
#20227
high Confidence
Subject:
Polymorphous_adenocarcinoma
(Adenocarcinoma)
→
shows
→
Object:
alterations_in_polymorphous_adenocarcinoma-associated_gene
(Genomic variation)
Original: 20 cases of polymorphous adenocarcinoma#exhibited#alterations in at least one polymorphous adenocarcinoma-associated gene
#20223
high Confidence
Subject:
tumor
(Tumor)
→
contains
→
Object:
TERT_promoter_rearrangement
(Gene rearrangement)
Original: Tumor#contains#a novel telomerase reverse transcriptase promoter rearrangement
#19602
middle Confidence
Subject:
distinct_group_by_tSNE
(Molecular typing)
→
is_formed_by
→
Object:
IDH2_mutant
(Gene mutation)
Original: IDH2 mutants#form#one distinct group by t-distributed stochastic neighbor embedding
#19601
middle Confidence
Subject:
IDH2_mutant
(Gene mutation)
→
forms
→
Object:
distinct_group_by_tSNE
(Molecular typing)
Original: IDH2 mutants#form#one distinct group by t-distributed stochastic neighbor embedding
#19559
middle Confidence
Subject:
luminal_CK8
(Cytoskeletal proteins)
→
increased_expression_in
→
Object:
non_TNBrCa
(Breast cancer subtypes)
Original: non-TNBrCa in women younger than 35#demonstrated increased expression of#luminal CK8
#18257
middle Confidence
Subject:
IDH2_mutated_sinonasal_tumor_cohort
(Tumor Cohort)
→
has
→
Object:
distinct_features
(Disease phenotype)
Original: IDH2-mutated sinonasal tumor cohort#has#distinct features
#17905
middle Confidence
Subject:
variant_patterns_of_AIS
(Tumor subtype)
→
include
→
Object:
intestinal_subtype
(Tumor subtype)
Original: variant patterns of AIS#include#endocervical/ endometrioid/ and intestinal subtypes
#17904
middle Confidence
Subject:
variant_patterns_of_AIS
(Tumor subtype)
→
include
→
Object:
endometrioid_subtype
(Tumor subtype)
Original: variant patterns of AIS#include#endocervical/ endometrioid/ and intestinal subtypes
#17903
middle Confidence
Subject:
variant_patterns_of_AIS
(Tumor subtype)
→
include
→
Object:
endocervical_subtype
(Tumor subtype)
Original: variant patterns of AIS#include#endocervical/ endometrioid/ and intestinal subtypes
#17438
middle Confidence
Subject:
foci_of_anaplastic_carcinoma
(Tumor lesions)
→
classified_into
→
Object:
pleomorphic_group
(Tumor subtype)
Original: foci/nodules of anaplastic carcinoma#were classified into#rhabdoid/ sarcomatoid/ pleomorphic groups
#17437
middle Confidence
Subject:
foci_of_anaplastic_carcinoma
(Tumor lesions)
→
classified_into
→
Object:
sarcomatoid_group
(Tumor subtype)
Original: foci/nodules of anaplastic carcinoma#were classified into#rhabdoid/ sarcomatoid/ pleomorphic groups
#17436
middle Confidence
Subject:
foci_of_anaplastic_carcinoma
(Tumor lesions)
→
classified_into
→
Object:
rhabdoid_group
(Tumor subtype)
Original: foci/nodules of anaplastic carcinoma#were classified into#rhabdoid/ sarcomatoid/ pleomorphic groups
#17105
middle Confidence
Subject:
XGC_RCC
(Kidney Cancer Subtypes)
→
shares
→
Object:
ESC_RCC
(Kidney Cancer Subtypes)
Original: XGC RCC#shares#clinicopathological and molecular characteristics with ESC RCC
#15654
middle Confidence
Subject:
BRAF_V600E_mutation
(Gene mutation)
→
is_absent_in
→
Object:
indeterminate_dendritic_cell_tumor
(disease)
Original: BRAF V600E mutations#were not present in#any of the four cases
#15388
middle Confidence
Subject:
tumors
(Tumor)
→
have
→
Object:
altered_expression_of_SMARCB1
(Abnormal gene expression)
Original: tumors#have#altered expression of SMARCB1
#14876
middle Confidence
Subject:
PRKD3_split
(Gene disruption)
→
coexists_with
→
Object:
PRKD1_E710D_mutation
(Gene mutation)
Original: One case#showed#coexisting PRKD3 split and PRKD1 E710D
#13849
middle Confidence
Subject:
NB_iCSCs
(Cancer stem cells)
→
shared
→
Object:
LCN_phenotype
(Disease phenotype)
Original: NB iCSCs#shared#LCN phenotype and high MYC/MYCN expression
#13132
middle Confidence
Subject:
vesicular_nuclear_chromatin
(Chromatin structure)
→
are_correlated_with
→
Object:
basal-like_phenotype
(Disease molecular subtypes)
Original: prominent nucleoli and vesicular nuclear chromatin#were correlated with#basal-like phenotype
#13131
middle Confidence
Subject:
prominent_nucleoli
(Organelles)
→
are_correlated_with
→
Object:
basal-like_phenotype
(Disease molecular subtypes)
Original: prominent nucleoli and vesicular nuclear chromatin#were correlated with#basal-like phenotype
#8065
middle Confidence
Subject:
medullary_carcinoma
(Tumor diseases)
→
shows
→
Object:
basal-like_immunophenotype
(Immunophenotype)
Original: medullary carcinomas#showed#basal-like immunophenotype
#7131
middle Confidence
Subject:
receptor_status
(Receptor status)
→
is_compared_in
→
Object:
EP-_breast_cancer
(Breast cancer molecular subtypes)
Original: Receptor status#is compared in#E+P+ versus E-P- breast cancer
#7130
middle Confidence
Subject:
receptor_status
(Receptor status)
→
is_compared_in
→
Object:
E+P+_breast_cancer
(Breast cancer molecular subtypes)
Original: Receptor status#is compared in#E+P+ versus E-P- breast cancer
#6574
middle Confidence
Subject:
transcriptomic_profiles
(Transcriptome data)
→
were_analyzed_for
→
Object:
normal_renal_tissue
(Normal kidney tissue)
Original: Transcriptomic profiles#were analyzed for#XGC RCC/ LOT/ HOT/EVT/ ESC RCC/ ChRCC/ RO/ ccRCC/ and normal renal tissues
#6573
middle Confidence
Subject:
transcriptomic_profiles
(Transcriptome data)
→
were_analyzed_for
→
Object:
ccRCC
(Kidney Cancer Subtypes)
Original: Transcriptomic profiles#were analyzed for#XGC RCC/ LOT/ HOT/EVT/ ESC RCC/ ChRCC/ RO/ ccRCC/ and normal renal tissues
#6572
middle Confidence
Subject:
transcriptomic_profiles
(Transcriptome data)
→
were_analyzed_for
→
Object:
RO
(Kidney Cancer Subtypes)
Original: Transcriptomic profiles#were analyzed for#XGC RCC/ LOT/ HOT/EVT/ ESC RCC/ ChRCC/ RO/ ccRCC/ and normal renal tissues
#6571
middle Confidence
Subject:
transcriptomic_profiles
(Transcriptome data)
→
were_analyzed_for
→
Object:
ChRCC
(Kidney Cancer Subtypes)
Original: Transcriptomic profiles#were analyzed for#XGC RCC/ LOT/ HOT/EVT/ ESC RCC/ ChRCC/ RO/ ccRCC/ and normal renal tissues
#6570
middle Confidence
Subject:
transcriptomic_profiles
(Transcriptome data)
→
were_analyzed_for
→
Object:
ESC_RCC
(Kidney Cancer Subtypes)
Original: Transcriptomic profiles#were analyzed for#XGC RCC/ LOT/ HOT/EVT/ ESC RCC/ ChRCC/ RO/ ccRCC/ and normal renal tissues
#6569
middle Confidence
Subject:
transcriptomic_profiles
(Transcriptome data)
→
were_analyzed_for
→
Object:
HOT_EVT
(Kidney Cancer Subtypes)
Original: Transcriptomic profiles#were analyzed for#XGC RCC/ LOT/ HOT/EVT/ ESC RCC/ ChRCC/ RO/ ccRCC/ and normal renal tissues
#6568
middle Confidence
Subject:
transcriptomic_profiles
(Transcriptome data)
→
were_analyzed_for
→
Object:
LOT
(Kidney Cancer Subtypes)
Original: Transcriptomic profiles#were analyzed for#XGC RCC/ LOT/ HOT/EVT/ ESC RCC/ ChRCC/ RO/ ccRCC/ and normal renal tissues
#6567
middle Confidence
Subject:
transcriptomic_profiles
(Transcriptome data)
→
were_analyzed_for
→
Object:
XGC_RCC
(Kidney Cancer Subtypes)
Original: Transcriptomic profiles#were analyzed for#XGC RCC/ LOT/ HOT/EVT/ ESC RCC/ ChRCC/ RO/ ccRCC/ and normal renal tissues