临床相关性:Therapeutic potential

A total of 7 records found

#16732 middle Confidence
Subject: Notoginsenoside_R1 (Natural small molecule compounds)
exhibits
Object: antitumor_effects_on_HeLa_cells (Cellular Processes)
Original: NGR1#exhibited#antitumor effects on cervical carcinoma cell lines (CaSki and HeLa cells)
🏥 Therapeutic potential 📄 PMID: 33537816
#16731 middle Confidence
Subject: Notoginsenoside_R1 (Natural small molecule compounds)
exhibits
Object: antitumor_effects_on_CaSki_cells (Cellular Processes)
Original: NGR1#exhibited#antitumor effects on cervical carcinoma cell lines (CaSki and HeLa cells)
🏥 Therapeutic potential 📄 PMID: 33537816
#16730 middle Confidence
Subject: Notoginsenoside_R1 (Natural small molecule compounds)
inhibits
Object: cancer_cell_proliferation (Cellular Processes)
Original: Notoginsenoside R1 (NGR1)#inhibited#proliferation of various types of cancer
🏥 Therapeutic potential 📄 PMID: 33537816
#12141 middle Confidence
Subject: RNA_Polymerase_I (RNA polymerase)
is_inhibited_by
Object: small_molecule_inhibitors (Small molecule inhibitors)
Original: Small molecule inhibitors of RNA Polymerase I#disrupt#nucleolar function
🏥 Therapeutic potential 🧬 POLR1A 📄 PMID: 24389329
#10691 middle Confidence
Subject: small_molecule_inhibitors (Small molecule inhibitors)
disrupt
Object: nucleolar_function (Nucleolar function)
Original: Small molecule inhibitors of RNA Polymerase I#disrupt#nucleolar function
🏥 Therapeutic potential 🧬 POLR1A 📄 PMID: 24389329
#3692 low Confidence
Subject: Hyperthermic_destruction (High temperature damage)
is_hypothesized_to_cause
Object: lysosomally_conditioned_selective_destruction (Cell Death Mechanism)
Original: Hyperthermic destruction of solid tumors#is hypothesized to cause#lysosomally conditioned selective destruction of malignant cells
🏥 Therapeutic potential 📄 PMID: 1253186
#1355 low Confidence
Subject: lysosomally_conditioned_selective_destruction (Lysosome-mediated selective destruction)
targets
Object: malignant_cells (Malignant cells)
Original: Hyperthermic destruction of solid tumors#is hypothesized to cause#lysosomally conditioned selective destruction of malignant cells
🏥 Therapeutic potential 📄 PMID: 1253186