临床相关性:Therapeutic targets

A total of 8 records found

#21645 high Confidence
Subject: RNA_polymerase_I (Enzymes)
is_a_target_of
Object: novel_drugs (Small molecule drugs)
Original: Novel drugs targeting RNA Polymerase I#are#viable targets for cancer therapies
🏥 Therapeutic targets 🧬 POLR1A 📄 PMID: 33805424
#20048 high Confidence
Subject: SGO2 (Protein coding genes)
knockdown_impedes
Object: cell_proliferation (Cellular Processes)
Original: SGO2 knockdown#impeded#cell proliferation/ cell migration/ invasion/ and EMT
🏥 Therapeutic targets 🧬 SGO2 📄 PMID: 39344317
#19871 middle Confidence
Subject: FGF5 (Growth Factors)
promotes
Object: migration (Cellular Processes)
Original: FGF5#promoted#proliferation/ invasion/ and migration of lung cancer cells
🏥 Therapeutic targets 🧬 FGF5 📄 PMID: 37186041
#19870 middle Confidence
Subject: FGF5 (Growth Factors)
promotes
Object: invasion (Cellular Processes)
Original: FGF5#promoted#proliferation/ invasion/ and migration of lung cancer cells
🏥 Therapeutic targets 🧬 FGF5 📄 PMID: 37186041
#19869 middle Confidence
Subject: FGF5 (Growth Factors)
promotes
Object: proliferation (Cellular Processes)
Original: FGF5#promoted#proliferation/ invasion/ and migration of lung cancer cells
🏥 Therapeutic targets 🧬 FGF5 📄 PMID: 37186041
#12189 middle Confidence
Subject: small_molecules (Small molecules)
target
Object: mutated_npm1_interactions (Protein Interactions)
Original: Small molecules#can target#mutated NPM1 interactions
🏥 Therapeutic targets 🧬 NPM1 📄 PMID: 19005479
#12104 middle Confidence
Subject: PLCG2 (Enzymes)
could_lead_to
Object: improved_cancer_treatment_strategies (Treatment strategies)
Original: Targeting PLCG2#could lead to#drug discovery and improved cancer treatment strategies
🏥 Therapeutic targets 🧬 PLCG2 📄 PMID: 39614428
#12103 middle Confidence
Subject: PLCG2 (Enzymes)
could_lead_to
Object: drug_discovery (Drug development)
Original: Targeting PLCG2#could lead to#drug discovery and improved cancer treatment strategies
🏥 Therapeutic targets 🧬 PLCG2 📄 PMID: 39614428