临床相关性：diagnosis
A total of 2758 records found
#22236
high Confidence
Subject:
TFEB_break-apart_FISH_assay
(Molecular detection technology)
→
supports
→
Object:
TFEB_RCC
(Kidney Cancer Subtypes)
Original: TFEB break-apart FISH assay#supports#diagnosis of TFEB RCC
#22222
high Confidence
Subject:
CD10
(Protease)
→
is_observed_in
→
Object:
renal_cell_carcinoma
(Renal cell carcinoma)
Original: CD10 immunoreactivity#was observed in#more than 90% of RCC
#22203
high Confidence
Subject:
Schwann_cells
(Cell Type)
→
are_positive_for
→
Object:
S100
(protein)
Original: Schwann cells#are positive for#S100
#22200
high Confidence
Subject:
rhabdomyoma
(Benign tumors)
→
is_a
→
Object:
benign_tumor
(Disease phenotype)
Original: Rhabdomyomas#are#rare benign tumors of striated muscle
#22196
high Confidence
Subject:
histopathological_evaluation
(Detection Methods)
→
is_essential_for
→
Object:
correct_diagnosis
(Diagnosis conclusion)
Original: histopathological evaluation#is essential for#correct diagnosis
#22195
high Confidence
Subject:
rhabdomyosarcoma
(Tumor type)
→
is
→
Object:
malignant_tumor
(Disease characteristics)
Original: rhabdomyosarcomas#are#malignant tumors with skeletal muscle differentiation
#22193
high Confidence
Subject:
Immunohistochemistry
(Detection Methods)
→
distinguishes
→
Object:
other_small_round_cell_tumors
(Tumor type)
Original: immunohistochemistry#distinguishes#Ewing sarcoma from other small round cell tumors
#22192
high Confidence
Subject:
Immunohistochemistry
(Detection Methods)
→
distinguishes
→
Object:
Ewing_sarcoma
(Tumor type)
Original: immunohistochemistry#distinguishes#Ewing sarcoma from other small round cell tumors
#22189
high Confidence
Subject:
perineural_invasion
(Histological characteristics)
→
is_diagnostic_marker_for
→
Object:
carcinoma_cells
(Tumor cells)
Original: features with 100% specificity and PPV#included#cytoplasmic mucin vacuole/ focal gland formation/ and perineural invasion
#22188
high Confidence
Subject:
focal_gland_formation
(Organizational structure characteristics)
→
is_diagnostic_marker_for
→
Object:
carcinoma_cells
(Tumor cells)
Original: features with 100% specificity and PPV#included#cytoplasmic mucin vacuole/ focal gland formation/ and perineural invasion
#22187
high Confidence
Subject:
cytoplasmic_mucin_vacuole
(Cell morphology)
→
is_diagnostic_marker_for
→
Object:
carcinoma_cells
(Tumor cells)
Original: features with 100% specificity and PPV#included#cytoplasmic mucin vacuole/ focal gland formation/ and perineural invasion
#22177
high Confidence
Subject:
Goblet_cells
(Epithelial cells)
→
confirm
→
Object:
Barrett's_esophagus
(disease)
Original: Goblet cells#are present in#all cases/ confirming their utility in defining Barrett's esophagus
#22176
high Confidence
Subject:
gastric_pyloric_gland_adenoma
(Tumor)
→
is
→
Object:
neoplasm_of_gastrointestinal_tract
(Disease phenotype)
Original: Gastric pyloric gland adenoma#is#a neoplasm of the gastrointestinal tract
#22175
high Confidence
Subject:
Fine-needle_aspiration
(Diagnostic techniques)
→
is
→
Object:
predominant_method_for_triaging_thyroid_nodules
(Diagnostic strategy)
Original: Fine-needle aspiration (FNA)#is#the predominant method for triaging thyroid nodules
#22173
high Confidence
Subject:
tumor_cells
(Cell Type)
→
expresses
→
Object:
HMB-45
(protein)
Original: tumor cells#expressed#S-100 protein and HMB-45
#22172
high Confidence
Subject:
tumor_cells
(Cell Type)
→
expresses
→
Object:
S-100_protein
(protein)
Original: tumor cells#expressed#S-100 protein and HMB-45
#22170
high Confidence
Subject:
CK20
(Structural proteins)
→
shows_positivity_ratio
→
Object:
lung_cancer
(Tumor type)
Original: Positivity ratios for CK20#are#17.2%/ 15.8%/ 13.5%/ and 32.2% for breast/ ovary/ stomach/ and lung cases respectively
#22169
high Confidence
Subject:
CK20
(Structural proteins)
→
shows_positivity_ratio
→
Object:
stomach_cancer
(Tumor type)
Original: Positivity ratios for CK20#are#17.2%/ 15.8%/ 13.5%/ and 32.2% for breast/ ovary/ stomach/ and lung cases respectively
#22168
high Confidence
Subject:
CK20
(Structural proteins)
→
shows_positivity_ratio
→
Object:
ovarian_cancer
(Tumor type)
Original: Positivity ratios for CK20#are#17.2%/ 15.8%/ 13.5%/ and 32.2% for breast/ ovary/ stomach/ and lung cases respectively
#22167
high Confidence
Subject:
CK20
(Structural proteins)
→
shows_positivity_ratio
→
Object:
breast_cancer
(Tumor type)
Original: Positivity ratios for CK20#are#17.2%/ 15.8%/ 13.5%/ and 32.2% for breast/ ovary/ stomach/ and lung cases respectively
#22166
high Confidence
Subject:
CK7
(Structural proteins)
→
shows_positivity_ratio
→
Object:
lung_cancer
(Tumor type)
Original: Positivity ratios for CK7#are#67.6%/ 63.5%/ 29.7%/ and 45.5% for breast/ ovary/ stomach/ and lung cases respectively
#22165
high Confidence
Subject:
CK7
(Structural proteins)
→
shows_positivity_ratio
→
Object:
stomach_cancer
(Tumor type)
Original: Positivity ratios for CK7#are#67.6%/ 63.5%/ 29.7%/ and 45.5% for breast/ ovary/ stomach/ and lung cases respectively
#22164
high Confidence
Subject:
CK7
(Structural proteins)
→
shows_positivity_ratio
→
Object:
ovarian_cancer
(Tumor type)
Original: Positivity ratios for CK7#are#67.6%/ 63.5%/ 29.7%/ and 45.5% for breast/ ovary/ stomach/ and lung cases respectively
#22163
high Confidence
Subject:
CK7
(Structural proteins)
→
shows_positivity_ratio
→
Object:
breast_cancer
(Tumor type)
Original: Positivity ratios for CK7#are#67.6%/ 63.5%/ 29.7%/ and 45.5% for breast/ ovary/ stomach/ and lung cases respectively
#22162
high Confidence
Subject:
giant_cells
(Tumor cells)
→
are_immunoreactive_for
→
Object:
CD68
(Lysosome-associated membrane proteins)
Original: giant cells#are immunoreactive for#CD68
#22161
high Confidence
Subject:
atypical_cells
(Tumor cells)
→
are_strongly_reactive_for
→
Object:
vimentin
(Intermediate filament protein)
Original: atypical cells#are strongly reactive for#vimentin
#22154
high Confidence
Subject:
t(X;18)_SYT/SSX1_translocation
(Gene translocation)
→
confirms
→
Object:
synovial_sarcoma
(Tumor type)
Original: molecular studies#showed#t(X; 18) SYT/SSX1 translocation confirming SS diagnosis
#22153
high Confidence
Subject:
molecular_studies
(Molecular testing)
→
showed
→
Object:
t(X;18)_SYT/SSX1_translocation
(Gene translocation)
Original: molecular studies#showed#t(X; 18) SYT/SSX1 translocation confirming SS diagnosis
#22152
high Confidence
Subject:
immunophenotypic_findings
(Immunophenotypic characteristics)
→
are_crucial_to
→
Object:
diagnosis_of_HAML
(Diagnostic behavior)
Original: Cognizance of typical cytologic/ histologic/ and immunophenotypic findings#is crucial to#establishing a diagnosis of HAML
#22151
high Confidence
Subject:
histologic_findings
(Histological characteristics)
→
are_crucial_to
→
Object:
diagnosis_of_HAML
(Diagnostic behavior)
Original: Cognizance of typical cytologic/ histologic/ and immunophenotypic findings#is crucial to#establishing a diagnosis of HAML
#22150
high Confidence
Subject:
cytologic_findings
(Cytological characteristics)
→
are_crucial_to
→
Object:
diagnosis_of_HAML
(Diagnostic behavior)
Original: Cognizance of typical cytologic/ histologic/ and immunophenotypic findings#is crucial to#establishing a diagnosis of HAML
#22149
high Confidence
Subject:
ALK_positive_lung_cancer
(Tumor subtype)
→
diagnosed_by
→
Object:
FISH
(Molecular detection technology)
Original: ALK (+) lung cancer#was diagnosed by#fluorescence in situ hybridization (FISH)
#22148
high Confidence
Subject:
Chromosomal_11;22_translocation
(Chromosomal mutations)
→
is_supportive_of
→
Object:
diagnosis_of_extraskeletal_Ewing's_sarcoma
(Diagnosis conclusion)
Original: Chromosomal 11;22 translocation#is supportive of#diagnosis of extraskeletal Ewing's sarcoma
#22145
high Confidence
Subject:
INI1_protein
(protein)
→
shows
→
Object:
loss_of_nuclear_expression_in_tumor_cell
(Protein expression status)
Original: INI1 protein#showed#a loss of nuclear expression in tumor cells
#22144
high Confidence
Subject:
Melan-A
(Protein markers)
→
is_detected_by
→
Object:
Immunostaining
(Detection Methods)
Original: Tumors#show#immunostaining for S-100/ HMB 45/ and Melan-A
#22143
high Confidence
Subject:
HMB45
(Protein markers)
→
is_detected_by
→
Object:
Immunostaining
(Detection Methods)
Original: Tumors#show#immunostaining for S-100/ HMB 45/ and Melan-A
#22142
high Confidence
Subject:
S100
(Protein markers)
→
is_detected_by
→
Object:
Immunostaining
(Detection Methods)
Original: Tumors#show#immunostaining for S-100/ HMB 45/ and Melan-A
#22136
high Confidence
Subject:
Wilms_tumor
(Tumor type)
→
is
→
Object:
malignant_renal_neoplasm_in_children
(Tumor type)
Original: Wilms' tumor (WT)#is#the most common malignant renal neoplasm in children
#22133
high Confidence
Subject:
IGLV2-14/IGLL5_fusion
(Gene fusion)
→
is_detected_by
→
Object:
next-generation_sequencing
(Molecular detection technology)
Original: Next-generation sequencing#demonstrated#a novel IGLV2-14/IGLL5 fusion and mutations or deletions in tumor suppressor genes such as PTPRB/ PPP2CB/ and UPK1A
#22122
high Confidence
Subject:
PSF-TFE3_fusion_gene
(Gene fusion products)
→
confirmed_by
→
Object:
reverse_transcription_PCR
(Detection Methods)
Original: PSF-TFE3 fusion genes#were confirmed by#reverse transcription polymerase chain reaction
#22057
high Confidence
Subject:
breast_carcinoma
(Tumor tissue)
→
were_assigned
→
Object:
tumor_grade
(Histological grading)
Original: fifty cases of breast carcinoma#were assigned#tumor grade
#22056
high Confidence
Subject:
histological_grading
(Histological grading)
→
was_done_according_to
→
Object:
Nottingham_modification_of_Scarff-Bloom-Richardson_method
(Grading method)
Original: histological grading#was done according to#Nottingham modification of Scarff-Bloom-Richardson method
#22054
high Confidence
Subject:
patient
(patient)
→
was_diagnosed_as
→
Object:
variant_hairy_cell_leukemia
(Rare leukemia subtypes)
Original: The patient#was diagnosed as#a case of variant hairy cell leukemia
#22047
high Confidence
Subject:
Nasopharyngeal_carcinoma
(Malignant tumors)
→
is_classified_as
→
Object:
Undifferentiated_carcinoma
(Histopathological type)
Original: Nasopharyngeal carcinoma (NPC)#is classified as#3 main types by WHO
#22046
high Confidence
Subject:
Nasopharyngeal_carcinoma
(Malignant tumors)
→
is_classified_as
→
Object:
Nonkeratinizing_carcinoma_differentiated
(Histopathological type)
Original: Nasopharyngeal carcinoma (NPC)#is classified as#3 main types by WHO
#22045
high Confidence
Subject:
Nasopharyngeal_carcinoma
(Malignant tumors)
→
is_classified_as
→
Object:
Keratinizing_squamous_cell_carcinoma
(Histopathological type)
Original: Nasopharyngeal carcinoma (NPC)#is classified as#3 main types by WHO
#22044
high Confidence
Subject:
three_significant_signs
(Clinical signs)
→
indicates
→
Object:
prostatic_duct_adenocarcinoma
(Prostatic ductal adenocarcinoma)
Original: Three significant signs and any additional signs#indicated#100% probability of PDAC
#22043
high Confidence
Subject:
histologic_section
(Tissue sections)
→
shows
→
Object:
mucinous_adenocarcinoma
(Mucinous adenocarcinoma)
Original: Histologic sections#showed#mucinous adenocarcinoma
#22040
high Confidence
Subject:
findings
(Clinical examination)
→
are_consistent_with
→
Object:
malignant_melanoma
(Disease phenotype)
Original: Findings#are consistent with#a diagnosis of malignant melanoma
#22038
high Confidence
Subject:
PET/CT_imaging
(Imaging technology)
→
demonstrates
→
Object:
splenic_mass
(Imaging findings)
Original: PET/CT imaging#demonstrates#hypermetabolic lymph nodes in neck/ abdomen/ thorax/ pelvis/ pulmonary nodules/ and a splenic mass
#22037
high Confidence
Subject:
PET/CT_imaging
(Imaging technology)
→
demonstrates
→
Object:
pulmonary_nodules
(Imaging findings)
Original: PET/CT imaging#demonstrates#hypermetabolic lymph nodes in neck/ abdomen/ thorax/ pelvis/ pulmonary nodules/ and a splenic mass
#22036
high Confidence
Subject:
PET/CT_imaging
(Imaging technology)
→
demonstrates
→
Object:
hypermetabolic_lymph_nodes
(Imaging findings)
Original: PET/CT imaging#demonstrates#hypermetabolic lymph nodes in neck/ abdomen/ thorax/ pelvis/ pulmonary nodules/ and a splenic mass
#22035
high Confidence
Subject:
Direct_sampling_of_cells_from_uterine_cavity
(Diagnostic techniques)
→
is_essential_for
→
Object:
detection_of_endometrial_carcinoma
(Diagnostic Process)
Original: Direct sampling of cells from the uterine cavity#is essential for#the detection of endometrial carcinoma
#22023
high Confidence
Subject:
Non-sebaceous_lymphadenoma
(Tumor type)
→
is
→
Object:
benign_tumor_of_salivary_glands
(Tumor phenotype)
Original: Non-sebaceous lymphadenoma#is#a benign tumor of salivary glands
#22018
high Confidence
Subject:
midline_carcinoma
(Tumor type)
→
is_diagnosed_in
→
Object:
upper_aerodigestive_tract
(Anatomical location)
Original: Midline carcinomas#are diagnosed in#head/ neck/ mediastinum/ and upper aerodigestive tract
#22017
high Confidence
Subject:
midline_carcinoma
(Tumor type)
→
is_diagnosed_in
→
Object:
mediastinum
(Anatomical location)
Original: Midline carcinomas#are diagnosed in#head/ neck/ mediastinum/ and upper aerodigestive tract
#22016
high Confidence
Subject:
midline_carcinoma
(Tumor type)
→
is_diagnosed_in
→
Object:
neck
(Anatomical location)
Original: Midline carcinomas#are diagnosed in#head/ neck/ mediastinum/ and upper aerodigestive tract
#22015
high Confidence
Subject:
midline_carcinoma
(Tumor type)
→
is_diagnosed_in
→
Object:
head
(Anatomical location)
Original: Midline carcinomas#are diagnosed in#head/ neck/ mediastinum/ and upper aerodigestive tract
#22014
high Confidence
Subject:
sex_cord_cell
(Cell Type)
→
is_positive_for
→
Object:
calretinin
(Protein markers)
Original: Sex cord cells#were small with#dense/ oval or angulated nuclei/ inconspicuous nucleoli/ and positivity for inhibin/ FOXL2/ SF1/ SOX9/ WT1/ and calretinin
#22013
high Confidence
Subject:
sex_cord_cell
(Cell Type)
→
is_positive_for
→
Object:
WT1
(Transcription Factors)
Original: Sex cord cells#were small with#dense/ oval or angulated nuclei/ inconspicuous nucleoli/ and positivity for inhibin/ FOXL2/ SF1/ SOX9/ WT1/ and calretinin
#22012
high Confidence
Subject:
sex_cord_cell
(Cell Type)
→
is_positive_for
→
Object:
SOX9
(Transcription Factors)
Original: Sex cord cells#were small with#dense/ oval or angulated nuclei/ inconspicuous nucleoli/ and positivity for inhibin/ FOXL2/ SF1/ SOX9/ WT1/ and calretinin
#22011
high Confidence
Subject:
sex_cord_cell
(Cell Type)
→
is_positive_for
→
Object:
SF1
(Transcription Factors)
Original: Sex cord cells#were small with#dense/ oval or angulated nuclei/ inconspicuous nucleoli/ and positivity for inhibin/ FOXL2/ SF1/ SOX9/ WT1/ and calretinin
#22010
high Confidence
Subject:
sex_cord_cell
(Cell Type)
→
is_positive_for
→
Object:
FOXL2
(Transcription Factors)
Original: Sex cord cells#were small with#dense/ oval or angulated nuclei/ inconspicuous nucleoli/ and positivity for inhibin/ FOXL2/ SF1/ SOX9/ WT1/ and calretinin
#22009
high Confidence
Subject:
sex_cord_cell
(Cell Type)
→
is_positive_for
→
Object:
inhibin
(Protein markers)
Original: Sex cord cells#were small with#dense/ oval or angulated nuclei/ inconspicuous nucleoli/ and positivity for inhibin/ FOXL2/ SF1/ SOX9/ WT1/ and calretinin
#21987
high Confidence
Subject:
excisional_biopsy
(Diagnostic Operations)
→
was_performed_on
→
Object:
lesion
(Diseased tissue)
Original: Excisional biopsy#was performed on#a lesion
#21985
high Confidence
Subject:
FISH analysis
(Detection Methods)
→
showed_presence_of
→
Object:
FUS-TFCP2_fusion
(Gene fusion)
Original: FISH analysis#showed presence of#FUS-TFCP2 fusion
#21963
high Confidence
Subject:
Interdigitating_dendritic_cell_tumor
(Rare tumors)
→
occurs_primarily_in
→
Object:
lymph_nodes
(Lymph nodes)
Original: Interdigitating dendritic cell tumor (IDCT)#occurs primarily in#lymph nodes
#21962
high Confidence
Subject:
Interdigitating_dendritic_cell_tumor
(Rare tumors)
→
is
→
Object:
extremely_rare_malignancy
(Disease characteristics)
Original: Interdigitating dendritic cell tumor (IDCT)#is#an extremely rare malignancy
#21956
high Confidence
Subject:
EWSR1-FLI1_fusion_transcript
(Fusion gene transcript)
→
is_detected_in
→
Object:
tumor_cells
(Tumor cells)
Original: The tumor#showed strong expression of#CD99/ FLI1/ and CD56 and was positive for the EWSR1-FLI1 fusion transcript
#21955
high Confidence
Subject:
CD56
(Cell adhesion molecules)
→
is_highly_expressed_in
→
Object:
tumor_cells
(Tumor cells)
Original: The tumor#showed strong expression of#CD99/ FLI1/ and CD56 and was positive for the EWSR1-FLI1 fusion transcript
#21954
high Confidence
Subject:
FLI1
(Transcription Factors)
→
is_highly_expressed_in
→
Object:
tumor_cells
(Tumor cells)
Original: The tumor#showed strong expression of#CD99/ FLI1/ and CD56 and was positive for the EWSR1-FLI1 fusion transcript
#21953
high Confidence
Subject:
CD99
(Cell surface proteins)
→
is_highly_expressed_in
→
Object:
tumor_cells
(Tumor cells)
Original: The tumor#showed strong expression of#CD99/ FLI1/ and CD56 and was positive for the EWSR1-FLI1 fusion transcript
#21951
high Confidence
Subject:
FNA_biopsy
(Diagnostic techniques)
→
yields_diagnosis_of
→
Object:
papillary_thyroid_carcinoma
(Tumor type)
Original: FNA biopsy#yields diagnosis of#papillary thyroid carcinoma
#21950
high Confidence
Subject:
pituitary_carcinomas
(Tumor cell type)
→
are_defined_as
→
Object:
primary_adenohypophyseal_tumors_with_metastasis
(Disease phenotype)
Original: pituitary carcinomas#are defined as#rare primary adenohypophyseal tumors with cerebrospinal or extracranial metastasis
#21949
high Confidence
Subject:
pleomorphic_epithelioid_cells
(Cell Type)
→
are_negative_for
→
Object:
desmin
(protein)
Original: pleomorphic epithelioid cells#are negative for#S100 protein/ desmin
#21948
high Confidence
Subject:
pleomorphic_epithelioid_cells
(Cell Type)
→
are_negative_for
→
Object:
S100_protein
(protein)
Original: pleomorphic epithelioid cells#are negative for#S100 protein/ desmin
#21947
high Confidence
Subject:
pleomorphic_epithelioid_cells
(Cell Type)
→
are_immunoreactive_for
→
Object:
calponin
(protein)
Original: pleomorphic epithelioid cells#are immunoreactive for#HMB-45/ MART-1/ actin/ vimentin/ calponin
#21946
high Confidence
Subject:
pleomorphic_epithelioid_cells
(Cell Type)
→
are_immunoreactive_for
→
Object:
vimentin
(protein)
Original: pleomorphic epithelioid cells#are immunoreactive for#HMB-45/ MART-1/ actin/ vimentin/ calponin
#21945
high Confidence
Subject:
pleomorphic_epithelioid_cells
(Cell Type)
→
are_immunoreactive_for
→
Object:
actin
(protein)
Original: pleomorphic epithelioid cells#are immunoreactive for#HMB-45/ MART-1/ actin/ vimentin/ calponin
#21944
high Confidence
Subject:
pleomorphic_epithelioid_cells
(Cell Type)
→
are_immunoreactive_for
→
Object:
MART-1
(protein)
Original: pleomorphic epithelioid cells#are immunoreactive for#HMB-45/ MART-1/ actin/ vimentin/ calponin
#21943
high Confidence
Subject:
pleomorphic_epithelioid_cells
(Cell Type)
→
are_immunoreactive_for
→
Object:
HMB-45
(protein)
Original: pleomorphic epithelioid cells#are immunoreactive for#HMB-45/ MART-1/ actin/ vimentin/ calponin
#21936
high Confidence
Subject:
Endoscopic_ultrasound-guided_fine_needle_aspiration
(Diagnostic Methods)
→
diagnoses
→
Object:
metastatic_sex_cord_tumor
(Tumor type)
Original: Endoscopic ultrasound-guided fine needle aspiration#diagnoses#metastatic sex cord tumor
#21935
high Confidence
Subject:
Immunohistochemical_stain
(Detection Methods)
→
confirmed
→
Object:
diagnosis_of_epithelioid_angiosarcoma
(Diagnosis conclusion)
Original: Immunohistochemical stain#confirmed#diagnosis of epithelioid angiosarcoma
#21927
high Confidence
Subject:
malignant_melanoma
(Tumor diseases)
→
is_diagnosed_by
→
Object:
fine_needle_aspiration_biopsy
(Diagnostic techniques)
Original: Malignant melanoma#is diagnosed by#fine needle aspiration (FNA) biopsy
#21922
high Confidence
Subject:
T_cells
(Immune cells)
→
display
→
Object:
monoclonal_T-cell_rearrangement_of_T-cell_receptor-gamma_chain
(Genetic variation)
Original: Cases#displayed#a monoclonal T-cell rearrangement of the T-cell receptor-gamma chain
#21921
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
expresses
→
Object:
EBER
(EBV-encoded RNA)
Original: Tumor cells#expressed#CD3/ cytotoxic protein/ and EBER
#21920
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
expresses
→
Object:
CD3
(cell marker molecules)
Original: Tumor cells#expressed#CD3/ cytotoxic protein/ and EBER
#21919
high Confidence
Subject:
CD20
(Differentiation antigen)
→
is_positively_expressed_in
→
Object:
tumor_cells
(Tumor cells)
Original: Tumor cells#revealed#positive expression of CD20 by Immunohistochemistry
#21918
high Confidence
Subject:
GATA3_immunostaining
(Immunohistochemistry)
→
is_helpful_in
→
Object:
diagnostic_metastatic_breast_carcinoma_in_thyroid_metastasis
(Diagnostic Process)
Original: GATA-3 immunostaining#was helpful in#diagnosing metastatic breast carcinoma in thyroid metastasis
#21916
high Confidence
Subject:
anaplastic_carcinoma
(Tumor type)
→
should_be_separated_from
→
Object:
carcinoma_showing_thymus-like_differentiation
(Tumor type)
Original: Anaplastic carcinoma#should be separated from#carcinoma showing thymus-like differentiation
#21915
high Confidence
Subject:
histopathologic_examination
(Pathological examination)
→
revealed
→
Object:
LGFMS
(Tumor type)
Original: Histopathologic examination#revealed#LGFMS
#21913
high Confidence
Subject:
Ewing_sarcoma/primitive_neuroectodermal_tumor
(Tumor)
→
is_a
→
Object:
small_round_cell_tumor
(Tumor phenotype)
Original: Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET)#is#a highly aggressive small round cell tumor
#21911
high Confidence
Subject:
CAM_5.2
(Cytokeratin)
→
is_positive_in
→
Object:
all_cases
(Case)
Original: AE1/AE3 and/or CAM 5.2#are positive in#all cases
#21910
high Confidence
Subject:
AE1/AE3
(Cytokeratin)
→
is_positive_in
→
Object:
all_cases
(Case)
Original: AE1/AE3 and/or CAM 5.2#are positive in#all cases
#21909
high Confidence
Subject:
cytological_ascitic_finding
(Cytology)
→
represented
→
Object:
malignant_feature_of_tumor
(Tumor phenotype)
Original: cytological ascitic findings#represent#malignant features of the tumor
#21905
high Confidence
Subject:
malignant_smear
(Cytology)
→
diagnoses_as
→
Object:
malignant
(Diagnosis)
Original: 137 smears#diagnosed as#"negative/" 45 of which confirmed malignant
#21904
high Confidence
Subject:
cytological_smear
(Cytology)
→
diagnoses_as
→
Object:
negative
(Diagnosis)
Original: 137 smears#diagnosed as#"negative/" 45 of which confirmed malignant
#21902
high Confidence
Subject:
IHC_markers
(Immunohistochemical markers)
→
are_valuable_for
→
Object:
final_diagnosis_of_amelanotic_melanoma
(Disease diagnosis)
Original: IHC markers#are valuable for#final diagnosis of amelanotic melanoma
#21894
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_reactive_for
→
Object:
CD20
(Immune markers)
Original: Tumor cells#were reactive for#CD45/ CD20
#21893
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_reactive_for
→
Object:
CD45
(Immune markers)
Original: Tumor cells#were reactive for#CD45/ CD20
#21892
high Confidence
Subject:
malignant_rhabdoid_tumor
(Tumor type)
→
is_characterized_by
→
Object:
prominent_nucleolus
(Cell morphology)
Original: Primary malignant rhabdoid tumor#is characterized by#hyaline cytoplasmic inclusions/ rounded or bean-shaped nucleus/ vesicular chromatin/ central prominent nucleolus
#21891
high Confidence
Subject:
malignant_rhabdoid_tumor
(Tumor type)
→
is_characterized_by
→
Object:
vesicular_chromatin
(Cell morphology)
Original: Primary malignant rhabdoid tumor#is characterized by#hyaline cytoplasmic inclusions/ rounded or bean-shaped nucleus/ vesicular chromatin/ central prominent nucleolus
#21890
high Confidence
Subject:
malignant_rhabdoid_tumor
(Tumor type)
→
is_characterized_by
→
Object:
rounded_nucleus
(Cell morphology)
Original: Primary malignant rhabdoid tumor#is characterized by#hyaline cytoplasmic inclusions/ rounded or bean-shaped nucleus/ vesicular chromatin/ central prominent nucleolus
#21889
high Confidence
Subject:
malignant_rhabdoid_tumor
(Tumor type)
→
is_characterized_by
→
Object:
hyaline_cytoplasmic_inclusions
(Cell morphology)
Original: Primary malignant rhabdoid tumor#is characterized by#hyaline cytoplasmic inclusions/ rounded or bean-shaped nucleus/ vesicular chromatin/ central prominent nucleolus
#21888
high Confidence
Subject:
lymph_node_biopsy
(Clinical testing)
→
confirmed
→
Object:
mantle_cell_lymphoma
(disease)
Original: lymph node biopsy#confirmed#mantle cell lymphoma
#21880
high Confidence
Subject:
MYB_immunoexpression
(Protein expression characteristics)
→
is_common_in
→
Object:
ACC
(Tumor type)
Original: MYB immunoexpression#is common in#ACC
#21879
high Confidence
Subject:
CD7
(T cell markers)
→
is_negative_in
→
Object:
neoplastic_cells
(Tumor cells)
Original: neoplastic cells#are negative for#T-cell markers (CD2/ CD3/ CD5/ CD7)
#21878
high Confidence
Subject:
CD5
(T cell markers)
→
is_negative_in
→
Object:
neoplastic_cells
(Tumor cells)
Original: neoplastic cells#are negative for#T-cell markers (CD2/ CD3/ CD5/ CD7)
#21877
high Confidence
Subject:
CD3
(T cell markers)
→
is_negative_in
→
Object:
neoplastic_cells
(Tumor cells)
Original: neoplastic cells#are negative for#T-cell markers (CD2/ CD3/ CD5/ CD7)
#21876
high Confidence
Subject:
CD2
(T cell markers)
→
is_negative_in
→
Object:
neoplastic_cells
(Tumor cells)
Original: neoplastic cells#are negative for#T-cell markers (CD2/ CD3/ CD5/ CD7)
#21874
high Confidence
Subject:
PAX5
(Transcription Factors)
→
is_expressed_in
→
Object:
neoplastic_cells
(Tumor cells)
Original: neoplastic cells#express#B-cell markers (CD19/ CD20/ CD79a/ PAX5/ BCL-2)
#21873
high Confidence
Subject:
CD79A
(B cell markers)
→
is_expressed_in
→
Object:
neoplastic_cells
(Tumor cells)
Original: neoplastic cells#express#B-cell markers (CD19/ CD20/ CD79a/ PAX5/ BCL-2)
#21872
high Confidence
Subject:
CD20
(B cell markers)
→
is_expressed_in
→
Object:
neoplastic_cells
(Tumor cells)
Original: neoplastic cells#express#B-cell markers (CD19/ CD20/ CD79a/ PAX5/ BCL-2)
#21871
high Confidence
Subject:
CD19
(B cell markers)
→
is_expressed_in
→
Object:
neoplastic_cells
(Tumor cells)
Original: neoplastic cells#express#B-cell markers (CD19/ CD20/ CD79a/ PAX5/ BCL-2)
#21866
high Confidence
Subject:
Necrosis
(Cell death process)
→
is_important_for
→
Object:
diagnosis_of_uterine_leiomyosarcoma
(Disease diagnosis)
Original: Presence of mitosis and/or necrosis#is important for#diagnosis of uterine leiomyosarcoma
#21865
high Confidence
Subject:
Mitosis
(Cellular Processes)
→
is_important_for
→
Object:
diagnosis_of_uterine_leiomyosarcoma
(Disease diagnosis)
Original: Presence of mitosis and/or necrosis#is important for#diagnosis of uterine leiomyosarcoma
#21864
high Confidence
Subject:
serum_AFP
(Serum biomarkers)
→
has_adjunctive_role_in
→
Object:
HCC
(Tumor type)
Original: The cytologic features of fine needle aspiration biopsies from well- and poorly differentiated HCC#were reviewed and#the adjunctive role of serum AFP/ HBV markers and radiologic findings evaluated
#21863
high Confidence
Subject:
CD10
(Protein markers)
→
indicates
→
Object:
endometrial_stroma
(Interstitial tissue)
Original: CD10 marker#indicates#endometrial stroma
#21860
high Confidence
Subject:
ROS1-rearranged_lung_adenocarcinoma
(Molecular classification of tumors)
→
has_been_identified
→
Object:
lung_adenocarcinoma
(Tumor type)
Original: ROS1-rearranged lung adenocarcinoma#has been#recently identified
#21859
high Confidence
Subject:
Cysts
(Cyst structure)
→
are_lined_by
→
Object:
single_layer_of_flattened_cuboidal_columnar_and_hobnail_epithelium
(Epithelial type)
Original: Cysts#are lined by#a single layer of flattened/ cuboidal/columnar/ and hobnail epithelium
#21857
high Confidence
Subject:
Tubulocystic_renal_cell_carcinoma
(Kidney tumors)
→
is_a
→
Object:
rare_kidney_neoplasm
(Kidney tumors)
Original: Tubulocystic renal cell carcinoma#is#a rare kidney neoplasm with low metastatic tendency
#21854
high Confidence
Subject:
diagnostic_criteria
(Diagnostic criteria)
→
are_defined_for
→
Object:
limited_adenocarcinoma_of_prostate
(Disease Type)
Original: diagnostic criteria#are defined for#limited adenocarcinoma of the prostate
#21853
high Confidence
Subject:
diagnosis
(Diagnosis conclusion)
→
is
→
Object:
spindle_cell_carcinoma
(Disease Type)
Original: Diagnosis#is#spindle cell carcinoma
#21851
high Confidence
Subject:
RT-PCR
(Molecular detection technology)
→
revealed
→
Object:
NAB2_STAT6_fusion_gene
(Fusion gene)
Original: RT-PCR#revealed#NAB2-STAT6 fusion gene
#21843
high Confidence
Subject:
PD-L1_expression
(Protein expression)
→
was_detected_by
→
Object:
Immunohistochemistry
(Detection Technology)
Original: PD-L1 expression#was detected by#immunohistochemistry using PD-L1 22C3 IHC assay
#21838
high Confidence
Subject:
Goblet_cells
(Epithelial cells)
→
are_present_in
→
Object:
Barrett's_esophagus
(disease)
Original: Goblet cells#are present in#all cases/ confirming their utility in defining Barrett's esophagus
#21837
high Confidence
Subject:
neoplasm
(Tumor)
→
was_identified_as
→
Object:
malignant_granulosa-theca_cell_tumor
(Disease phenotype)
Original: neoplasm#was identified as#a malignant granulosa-theca cell tumor
#21804
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
label_with
→
Object:
MUC5AC
(Secretory mucin)
Original: Neoplastic cells#label with#markers of gastric pyloric gland differentiation
#21803
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
label_with
→
Object:
MUC6
(Secretory mucin)
Original: Neoplastic cells#label with#markers of gastric pyloric gland differentiation
#21802
high Confidence
Subject:
CD10_immunostaining
(Immunohistochemistry)
→
is_helpful_in
→
Object:
separating_metastatic_RCC_from_primary_ACN
(Diagnostic Process)
Original: CD10 immunostaining#is helpful in#separating metastatic RCC from primary ACN
#21799
high Confidence
Subject:
PSA
(protein)
→
is_used_as
→
Object:
prostatic_carcinoma_detection
(Disease phenotype)
Original: Immunocytochemical detection of PSA#was recognized as#a useful mean for prostatic carcinoma detection
#21798
high Confidence
Subject:
PSA
(Protein markers)
→
is_useful_in
→
Object:
cytology_specimen_detection
(Diagnostic testing)
Original: Prostate-specific antigen (PSA)#is useful in#cytology specimen detection
#21782
high Confidence
Subject:
S100
(protein)
→
is_upregulated_in
→
Object:
melanoma
(Tumor)
Original: melanoma#is characterized by#large pleomorphic cells with eosinophilic cytoplasm/ prominent nucleoli/ and S100 protein
#21779
high Confidence
Subject:
lymphocytic_smear_background
(Cell morphology)
→
indicates
→
Object:
type_B_thymomas
(Tumor type)
Original: lymphocytic smear background#indicated#type B thymomas in 87.5% of cases
#21778
high Confidence
Subject:
NUT_midline_carcinoma
(Tumor diseases)
→
shows_positive_immunostaining_with
→
Object:
NUT_antibody
(Diagnostic Antibodies)
Original: NMC#has#characteristic morphological features and positive immunostaining with NUT antibody
#21777
high Confidence
Subject:
NUT
(Protein coding genes)
→
rearrangement_detected_by
→
Object:
RT-PCR
(Diagnostic techniques)
Original: The diagnosis of NMC#is made by#demonstration of NUT rearrangement via immunohistochemistry/ FISH/ or RT-PCR
#21776
high Confidence
Subject:
NUT
(Protein coding genes)
→
rearrangement_detected_by
→
Object:
FISH
(Diagnostic techniques)
Original: The diagnosis of NMC#is made by#demonstration of NUT rearrangement via immunohistochemistry/ FISH/ or RT-PCR
#21775
high Confidence
Subject:
NUT
(Protein coding genes)
→
rearrangement_detected_by
→
Object:
Immunohistochemistry
(Diagnostic techniques)
Original: The diagnosis of NMC#is made by#demonstration of NUT rearrangement via immunohistochemistry/ FISH/ or RT-PCR
#21773
high Confidence
Subject:
Fluorescence_in_situ_hybridisation_technique
(Molecular detection technology)
→
has_established_its_role_in
→
Object:
diagnosis_of_lymphoid_malignancies
(Tumor disease diagnosis)
Original: Fluorescence in-situ hybridisation technique#has established its role in#diagnosis of lymphoid malignancies
#21772
high Confidence
Subject:
tumor
(Tumor tissue)
→
is_positive_for
→
Object:
vimentin
(Cytoskeletal proteins)
Original: tumor#is positive for#keratins and vimentin
#21771
high Confidence
Subject:
tumor
(Tumor tissue)
→
is_positive_for
→
Object:
keratins
(Cytoskeletal proteins)
Original: tumor#is positive for#keratins and vimentin
#21768
high Confidence
Subject:
cytologic_diagnosis
(Diagnosis conclusion)
→
is
→
Object:
adenocarcinoma
(Adenocarcinoma)
Original: Cytologic diagnosis#was made as#adenocarcinoma
#21767
high Confidence
Subject:
intranodal_palisaded_myofibroblastoma
(Tumor type)
→
is_a
→
Object:
rare_lymph_node_mesenchymal_neoplasm
(Tumor phenotype)
Original: intranodal palisaded myofibroblastoma#is a#rare lymph node mesenchymal neoplasm
#21766
high Confidence
Subject:
melanotic_schwannoma
(Tumor type)
→
is_a
→
Object:
rare_pigmented_neural_tumor
(Tumor phenotype)
Original: melanotic schwannoma (MS)#is a#rare pigmented neural tumor
#21763
high Confidence
Subject:
Dnajb1-Prkaca_gene_fusion
(Gene fusion)
→
is_contained_in
→
Object:
human_FL-HCCs
(Tumor type)
Original: The tumors#contained#the Dnajb1-Prkaca gene fusion
#21762
high Confidence
Subject:
Needle_aspiration_cytology
(Cytology)
→
is_used_for
→
Object:
acinar-cell_carcinoma_diagnosis
(Acinar Cell Carcinoma Diagnosis)
Original: Needle aspiration cytology#is used for#acinar-cell carcinoma diagnosis
#21761
high Confidence
Subject:
Basal_cell_layer
(Basal cell layer)
→
is_lacking_in
→
Object:
prostatic_intraepithelial_neoplasia
(Prostatic intraepithelial neoplasia)
Original: Basal cell layer (BCL)#is lacking in#prostatic intraepithelial neoplasia (PMC)
#21760
high Confidence
Subject:
immunostaining_with_anticytokeratin_antibodies
(Immunohistochemistry)
→
is_significant_for
→
Object:
differential_diagnosis
(Diagnostic Process)
Original: Immunostaining with anticytokeratin antibodies#is significant for#differential diagnosis
#21754
high Confidence
Subject:
neoplastic_melanocyte
(Tumor cells)
→
expresses
→
Object:
melanoma_antigen
(Tumor Antigens)
Original: Neoplastic melanocytes#express#vimentin/ S100 protein/ melan-A/ and melanoma antigen
#21753
high Confidence
Subject:
neoplastic_melanocyte
(Tumor cells)
→
expresses
→
Object:
melan-A
(melanin-related antigen)
Original: Neoplastic melanocytes#express#vimentin/ S100 protein/ melan-A/ and melanoma antigen
#21752
high Confidence
Subject:
neoplastic_melanocyte
(Tumor cells)
→
expresses
→
Object:
S100_protein
(Calcium Binding Protein)
Original: Neoplastic melanocytes#express#vimentin/ S100 protein/ melan-A/ and melanoma antigen
#21751
high Confidence
Subject:
neoplastic_melanocyte
(Tumor cells)
→
expresses
→
Object:
vimentin
(Intermediate filament protein)
Original: Neoplastic melanocytes#express#vimentin/ S100 protein/ melan-A/ and melanoma antigen
#21750
high Confidence
Subject:
neoplastic_trichoblast
(Tumor cells)
→
expresses
→
Object:
E-cadherin
(Cell adhesion molecules)
Original: Neoplastic trichoblasts#express#cytokeratins and E-cadherin
#21749
high Confidence
Subject:
neoplastic_trichoblast
(Tumor cells)
→
expresses
→
Object:
cytokeratins
(Structural proteins)
Original: Neoplastic trichoblasts#express#cytokeratins and E-cadherin
#21748
high Confidence
Subject:
patient
(patient)
→
diagnosed_with
→
Object:
Muir-Torre_syndrome
(disease)
Original: The patient#was diagnosed with#Muir-Torre syndrome
#21747
high Confidence
Subject:
tumor
(Tumor cell clusters)
→
is_diagnosed_as
→
Object:
PHNET_G2
(Extrahepatic neuroendocrine tumor grading)
Original: tumor#is diagnosed as#a PHNET G2
#21746
high Confidence
Subject:
histopathological_examination
(Histological examination)
→
reveals
→
Object:
primitive_neuroectodermal_tumor
(Tumor type)
Original: histopathological examination#reveals#a primitive neuroectodermal tumor (PNET)
#21745
high Confidence
Subject:
tumor
(Tumor cell clusters)
→
is_located_in
→
Object:
tail_of_pancreas
(Anatomical location)
Original: tumor#is located in#the tail of the pancreas
#21741
high Confidence
Subject:
Perivascular_epithelioid_cells
(Tumor cells)
→
are_present_in
→
Object:
PEComas
(Tumor)
Original: Perivascular epithelioid cells (PECs)#are present in#a group of tumors called PEComas
#21740
high Confidence
Subject:
EGFR_mutation
(Gene mutation)
→
is_described_in
→
Object:
adenocarcinoma_of_the_lung
(Disease phenotype)
Original: EGFR mutations#are described in#adenocarcinomas of the lung
#21725
high Confidence
Subject:
NONO-TFE3_dual-fusion_FISH_probe
(Molecular diagnostic tools)
→
is_effective_for
→
Object:
diagnosing_NONO-TFE3_RCC
(Diagnostic Process)
Original: NONO-TFE3 dual-fusion FISH probe#is effective for#diagnosing NONO-TFE3 RCC
#21724
high Confidence
Subject:
tumor
(Tumor)
→
diagnosed_as
→
Object:
presumed_spontaneous_astrocytoma
(Tumor)
Original: Tumor#diagnosed as#a presumed spontaneous astrocytoma
#21712
high Confidence
Subject:
splenic_marginal_zone_lymphoma
(Neoplastic diseases)
→
is_diagnosed_in
→
Object:
22-year-old_woman
(Specific populations)
Original: splenic marginal zone lymphoma#is diagnosed in#a 22-year-old woman
#21707
high Confidence
Subject:
meningiomas
(Tumor type)
→
are_classified_into
→
Object:
anaplastic_grade_III
(Anaplastic meningioma)
Original: Meningiomas#are classified into#benign (grade I)/ atypical (grade II)/ and anaplastic (grade III)
#21706
high Confidence
Subject:
meningiomas
(Tumor type)
→
are_classified_into
→
Object:
atypical_grade_II
(Atypical meningioma)
Original: Meningiomas#are classified into#benign (grade I)/ atypical (grade II)/ and anaplastic (grade III)
#21705
high Confidence
Subject:
meningiomas
(Tumor type)
→
are_classified_into
→
Object:
benign_grade_I
(Benign meningioma)
Original: Meningiomas#are classified into#benign (grade I)/ atypical (grade II)/ and anaplastic (grade III)
#21703
high Confidence
Subject:
patient
(patient)
→
was_diagnosed_with
→
Object:
grade_IV_osteoblastic_osteosarcoma
(Disease classification)
Original: patient#was diagnosed with#grade IV osteoblastic osteosarcoma
#21701
high Confidence
Subject:
solid_type_primary_pulmonary_ACC
(Tumor type)
→
diagnosed_by
→
Object:
bronchoscope_guided_fine_needle_aspiration
(Diagnostic techniques)
Original: Solid-type primary pulmonary ACC#diagnosed by#bronchoscope-guided fine needle aspiration
#21694
high Confidence
Subject:
Immunohistochemical_staining_for_HER2
(Protein expression detection)
→
shows
→
Object:
negative_score_0
(Protein expression status)
Original: Immunohistochemical staining for Her2#was found to be#negative (score 0)
#21693
high Confidence
Subject:
TNM_classification
(Diagnostic grading system)
→
diagnoses_as
→
Object:
T1cN0M0_stage_I
(Tumor stage)
Original: TNM classification#was diagnosed as#T1cN0M0 stage I
#21692
high Confidence
Subject:
Fine-needle_aspiration_cytology
(Diagnostic techniques)
→
is_performed_for
→
Object:
extraskeletal_Ewing's_sarcoma
(Neoplastic diseases)
Original: Fine-needle aspiration cytology#is performed for#extraskeletal Ewing's sarcoma
#21688
high Confidence
Subject:
Anaplastic_Wilms_Tumor
(Tumor type)
→
diagnosed_according to
→
Object:
BECKWITH_and_PALMER_criteria_1978
(Diagnostic criteria)
Original: Anaplastic WT#are diagnosed according to#criteria of BECKWITH and PALMER (1978)
#21679
high Confidence
Subject:
hereditary_leiomyomatosis_and_renal_cell_carcinoma
(disease)
→
is_defined_by
→
Object:
germline_mutation_of_FH_gene
(Gene mutation)
Original: Hereditary leiomyomatosis and renal cell carcinoma#is defined by#germline mutation of FH gene
#21677
high Confidence
Subject:
EWSR1
(Gene)
→
is_rearranged_in
→
Object:
malignant_gastrointestinal_neuroectodermal_tumor
(Tumor diseases)
Original: fluorescence in situ hybridization analysis#demonstrated#EWSR1 rearrangement in both tumors
#21676
high Confidence
Subject:
systematic_approach
(Diagnostic Methods)
→
enables
→
Object:
cancer_diagnosis
(Diagnosis conclusion)
Original: Systematic approach#enables#correct cancer diagnosis in most cases during routine daily practice
#21544
high Confidence
Subject:
cytological_examination
(Cytology)
→
distinguishes
→
Object:
malignant_cases
(Malignant cases)
Original: cytological examination#distinguishes#benign from malignant cases
#21543
high Confidence
Subject:
cytological_examination
(Cytology)
→
distinguishes
→
Object:
benign_cases
(Benign cases)
Original: cytological examination#distinguishes#benign from malignant cases
#21515
high Confidence
Subject:
biopsy_specimen
(Biopsy specimen)
→
confirmed
→
Object:
diagnosis_of_BL
(Burkitt Lymphoma Diagnosis)
Original: Biopsy specimens#confirmed#the diagnosis of BL
#21513
high Confidence
Subject:
Adenomatoid_tumor
(Tumor type)
→
is
→
Object:
primary_neoplasm_of_paratesticular_area
(Tumor classification)
Original: Adenomatoid tumor#is#one of the most common primary neoplasms of the paratesticular area
#21510
high Confidence
Subject:
Nuclear_parameters
(Nuclear parameters)
→
are_valuable_discriminants_between
→
Object:
renal_oncocytoma
(Tumor type)
Original: Nuclear parameters#are valuable discriminants between#chromophobe renal cell carcinoma and renal oncocytoma
#21509
high Confidence
Subject:
Nuclear_parameters
(Nuclear parameters)
→
are_valuable_discriminants_between
→
Object:
chromophobe_renal_cell_carcinoma
(Tumor type)
Original: Nuclear parameters#are valuable discriminants between#chromophobe renal cell carcinoma and renal oncocytoma
#21504
high Confidence
Subject:
Nasopharyngeal_carcinoma
(Malignant tumors)
→
may_be_divided_into
→
Object:
Undifferentiated_carcinoma
(Histopathological type)
Original: Tumors#may be divided into#differentiated and undifferentiated carcinoma
#21503
high Confidence
Subject:
Nasopharyngeal_carcinoma
(Malignant tumors)
→
may_be_divided_into
→
Object:
Differentiated_carcinoma
(Histopathological type)
Original: Tumors#may be divided into#differentiated and undifferentiated carcinoma
#21501
high Confidence
Subject:
call-exner_body
(Organizational Structure)
→
is_characteristic_of
→
Object:
ovarian_tumor
(Tumor)
Original: Call-Exner's Bodies#are characteristic of#these tumors
#21494
high Confidence
Subject:
FNA_smears
(Cytology)
→
reveal
→
Object:
lymphocytes
(Immune cells)
Original: FNA smears#reveal#numerous CD1a+ and S-100+ Langerhans-type cells (LCs) along with eosinophils/ neutrophils/ and lymphocytes
#21493
high Confidence
Subject:
FNA_smears
(Cytology)
→
reveal
→
Object:
neutrophils
(Immune cells)
Original: FNA smears#reveal#numerous CD1a+ and S-100+ Langerhans-type cells (LCs) along with eosinophils/ neutrophils/ and lymphocytes
#21492
high Confidence
Subject:
FNA_smears
(Cytology)
→
reveal
→
Object:
Eosinophils
(Immune cells)
Original: FNA smears#reveal#numerous CD1a+ and S-100+ Langerhans-type cells (LCs) along with eosinophils/ neutrophils/ and lymphocytes
#21491
high Confidence
Subject:
FNA_smears
(Cytology)
→
reveal
→
Object:
S-100_positive_Langerhans-type_cells
(Immune cells)
Original: FNA smears#reveal#numerous CD1a+ and S-100+ Langerhans-type cells (LCs) along with eosinophils/ neutrophils/ and lymphocytes
#21490
high Confidence
Subject:
FNA_smears
(Cytology)
→
reveal
→
Object:
CD1a_positive_Langerhans-type_cells
(Immune cells)
Original: FNA smears#reveal#numerous CD1a+ and S-100+ Langerhans-type cells (LCs) along with eosinophils/ neutrophils/ and lymphocytes
#21489
high Confidence
Subject:
Diagnostic_smears
(Diagnostic techniques)
→
showed
→
Object:
suspicious_results_in_endometrial_cytology
(Diagnosis)
Original: Diagnostic smears#showed#positive and suspicious results in vaginal/ cervical/ and endometrial cytology
#21488
high Confidence
Subject:
Diagnostic_smears
(Diagnostic techniques)
→
showed
→
Object:
suspicious_results_in_cervical_cytology
(Diagnosis)
Original: Diagnostic smears#showed#positive and suspicious results in vaginal/ cervical/ and endometrial cytology
#21487
high Confidence
Subject:
Diagnostic_smears
(Diagnostic techniques)
→
showed
→
Object:
suspicious_results_in_vaginal_cytology
(Diagnosis)
Original: Diagnostic smears#showed#positive and suspicious results in vaginal/ cervical/ and endometrial cytology
#21486
high Confidence
Subject:
Diagnostic_smears
(Diagnostic techniques)
→
showed
→
Object:
positive_results_in_endometrial_cytology
(Diagnosis)
Original: Diagnostic smears#showed#positive and suspicious results in vaginal/ cervical/ and endometrial cytology
#21485
high Confidence
Subject:
Diagnostic_smears
(Diagnostic techniques)
→
showed
→
Object:
positive_results_in_cervical_cytology
(Diagnosis)
Original: Diagnostic smears#showed#positive and suspicious results in vaginal/ cervical/ and endometrial cytology
#21484
high Confidence
Subject:
Diagnostic_smears
(Diagnostic techniques)
→
showed
→
Object:
positive_results_in_vaginal_cytology
(Diagnosis)
Original: Diagnostic smears#showed#positive and suspicious results in vaginal/ cervical/ and endometrial cytology
#21483
high Confidence
Subject:
Abdominal_ultrasonography
(Imaging technology)
→
revealed
→
Object:
normal_findings
(Imaging findings)
Original: Computerized tomography/ gallium scintigraphy/ and abdominal ultrasonography#revealed#normal findings
#21482
high Confidence
Subject:
Gallium_scintigraphy
(Imaging technology)
→
revealed
→
Object:
normal_findings
(Imaging findings)
Original: Computerized tomography/ gallium scintigraphy/ and abdominal ultrasonography#revealed#normal findings
#21481
high Confidence
Subject:
Computerized_tomography
(Imaging technology)
→
revealed
→
Object:
normal_findings
(Imaging findings)
Original: Computerized tomography/ gallium scintigraphy/ and abdominal ultrasonography#revealed#normal findings
#21447
high Confidence
Subject:
voided_urine_cytology
(Urine cytology)
→
is_useful_for
→
Object:
follow-up_of_papillary_RCC
(Follow-up)
Original: voided urine cytology#is useful for#screening and follow-up of patients with papillary RCC
#21446
high Confidence
Subject:
voided_urine_cytology
(Urine cytology)
→
is_useful_for
→
Object:
screening_of_papillary_RCC
(Screening)
Original: voided urine cytology#is useful for#screening and follow-up of patients with papillary RCC
#21445
high Confidence
Subject:
histopathological_features
(Histological characteristics)
→
diagnose
→
Object:
pigmented_epithelioid_melanocytoma
(Tumor)
Original: Histopathological features#diagnose#pigmented epithelioid melanocytoma (PEM) in a teratoma of a Carney complex patient
#21444
high Confidence
Subject:
biopsy
(Histological examination)
→
diagnoses
→
Object:
sarcomatoid_carcinoma
(Tumor diseases)
Original: Diagnosis of sarcomatoid carcinoma#can be made by#CT/ MRI/ cytology/ and biopsy
#21443
high Confidence
Subject:
Cytology
(Cytology)
→
diagnoses
→
Object:
sarcomatoid_carcinoma
(Tumor diseases)
Original: Diagnosis of sarcomatoid carcinoma#can be made by#CT/ MRI/ cytology/ and biopsy
#21442
high Confidence
Subject:
MRI
(Imaging Technology)
→
diagnoses
→
Object:
sarcomatoid_carcinoma
(Tumor diseases)
Original: Diagnosis of sarcomatoid carcinoma#can be made by#CT/ MRI/ cytology/ and biopsy
#21441
high Confidence
Subject:
CT
(Imaging Technology)
→
diagnoses
→
Object:
sarcomatoid_carcinoma
(Tumor diseases)
Original: Diagnosis of sarcomatoid carcinoma#can be made by#CT/ MRI/ cytology/ and biopsy
#21412
high Confidence
Subject:
Tumor_cells
(Cell Type)
→
express
→
Object:
neuron-specific_enolase
(Enzymes)
Original: Tumor cells#were positive for#HMB-45 and neuron-specific enolase but negative for epithelial markers/ smooth muscle markers/ other neuroendocrine markers/ vimentin/ melan-A/ S-100 protein
#21411
high Confidence
Subject:
Tumor_cells
(Cell Type)
→
express
→
Object:
HMB-45
(Protein markers)
Original: Tumor cells#were positive for#HMB-45 and neuron-specific enolase but negative for epithelial markers/ smooth muscle markers/ other neuroendocrine markers/ vimentin/ melan-A/ S-100 protein
#21410
high Confidence
Subject:
Leishman_stained_smear
(Stained smear)
→
verifies
→
Object:
ductal_hyperplasia
(disease)
Original: Cases#are verified with#Leishman stained smears obtained by FNAB from patients with PDAC or ductal hyperplasia
#21409
high Confidence
Subject:
Leishman_stained_smear
(Stained smear)
→
verifies
→
Object:
PDAC
(disease)
Original: Cases#are verified with#Leishman stained smears obtained by FNAB from patients with PDAC or ductal hyperplasia
#21406
high Confidence
Subject:
AI_solution
(AI Algorithms)
→
achieved
→
Object:
human_expert_performance
(Human expert level)
Original: Solution#achieved#performance similar to human experts in analyzing nuclei and AgNORs
#21383
high Confidence
Subject:
nucleolar_organizer_regions
(Nucleolar organizer region)
→
acts_as
→
Object:
diagnostic_marker
(Diagnostic markers)
Original: Nucleolar organizer regions#act as#a prognostic indicator for stage I non-small cell lung cancer
#21366
high Confidence
Subject:
Immunohistochemical analysis
(Detection Methods)
→
revealed_positivity_for
→
Object:
myogenin
(Transcription Factors)
Original: immunohistochemical analysis#revealed positivity for#desmin/ MyoD1/ and myogenin
#21365
high Confidence
Subject:
Immunohistochemical analysis
(Detection Methods)
→
revealed_positivity_for
→
Object:
MyoD1
(Transcription Factors)
Original: immunohistochemical analysis#revealed positivity for#desmin/ MyoD1/ and myogenin
#21364
high Confidence
Subject:
Immunohistochemical analysis
(Detection Methods)
→
revealed_positivity_for
→
Object:
desmin
(protein)
Original: immunohistochemical analysis#revealed positivity for#desmin/ MyoD1/ and myogenin
#21363
high Confidence
Subject:
rhabdomyosarcoma
(Tumor type)
→
shows
→
Object:
skeletal_muscle_differentiation
(Cell differentiation characteristics)
Original: rhabdomyosarcomas#are#malignant tumors with skeletal muscle differentiation
#21345
high Confidence
Subject:
Bone_marrow_trephine_biopsy
(Pathological examination)
→
showed
→
Object:
acute_myelomonocytic_leukemia
(Hematologic malignancies)
Original: Bone marrow trephine biopsy#showed#acute myelomonocytic leukemia
#21344
high Confidence
Subject:
Adamantinoma-like_Ewing_sarcoma
(Tumor diseases)
→
is_characterized_as
→
Object:
Ewing_sarcoma
(Tumor diseases)
Original: Neoplasm#is characterized as#adamantinoma-like Ewing sarcoma
#21336
high Confidence
Subject:
atypical_adenomatous_hyperplasia
(Benign lesions)
→
is_distinguished_from
→
Object:
well-differentiated_prostatic_adenocarcinoma
(Tumor type)
Original: Diagnosis of atypical adenomatous hyperplasia (AAH)#is distinguished from#well-differentiated prostatic adenocarcinoma with small acinar pattern (PACsmac)
#21335
high Confidence
Subject:
percutaneous_fine-needle_aspiration_biopsy
(Clinical operation)
→
performed_on
→
Object:
liver
(organ)
Original: 1673 patients#underwent#percutaneous fine-needle aspiration biopsy of the liver
#21334
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_strongly_positive_for
→
Object:
FSCN1
(Actin-binding protein)
Original: Tumor cells#were strongly positive for#vimentin/ CD68/ S-100 protein/ CD45/leukocyte common antigen/ and fascin
#21333
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_strongly_positive_for
→
Object:
PTPRC
(common leukocyte antigen)
Original: Tumor cells#were strongly positive for#vimentin/ CD68/ S-100 protein/ CD45/leukocyte common antigen/ and fascin
#21332
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_strongly_positive_for
→
Object:
S100B
(Calcium Binding Protein)
Original: Tumor cells#were strongly positive for#vimentin/ CD68/ S-100 protein/ CD45/leukocyte common antigen/ and fascin
#21331
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_strongly_positive_for
→
Object:
CD68
(Macrophage markers)
Original: Tumor cells#were strongly positive for#vimentin/ CD68/ S-100 protein/ CD45/leukocyte common antigen/ and fascin
#21330
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_strongly_positive_for
→
Object:
VIM
(Cytoskeletal proteins)
Original: Tumor cells#were strongly positive for#vimentin/ CD68/ S-100 protein/ CD45/leukocyte common antigen/ and fascin
#21325
high Confidence
Subject:
excisional_biopsy
(Biopsy)
→
revealed
→
Object:
infiltration_with_diffuse_B-cell_leukemia_lymphoma
(Pathological manifestations)
Original: Excisional biopsy#revealed#infiltration with diffuse B-cell leukemia/lymphoma
#21324
high Confidence
Subject:
positron_emission_tomography_computed_tomography
(Imaging tests)
→
detected
→
Object:
increased_metabolic_activity_in_spleen
(Imaging findings)
Original: Positron emission tomography-computed tomography#detected#increased metabolic activity in multiple lymph nodes/ bone marrow/ and extremely enlarged spleen
#21323
high Confidence
Subject:
positron_emission_tomography_computed_tomography
(Imaging tests)
→
detected
→
Object:
increased_metabolic_activity_in_bone_marrow
(Imaging findings)
Original: Positron emission tomography-computed tomography#detected#increased metabolic activity in multiple lymph nodes/ bone marrow/ and extremely enlarged spleen
#21322
high Confidence
Subject:
positron_emission_tomography_computed_tomography
(Imaging tests)
→
detected
→
Object:
increased_metabolic_activity_in_lymph_nodes
(Imaging findings)
Original: Positron emission tomography-computed tomography#detected#increased metabolic activity in multiple lymph nodes/ bone marrow/ and extremely enlarged spleen
#21321
high Confidence
Subject:
positron_emission_tomography_with_FDG
(Imaging tests)
→
revealed
→
Object:
systemic_metastasis
(Disease phenotype)
Original: Computed tomography and positron emission tomography with fluorodeoxyglucose#revealed#systemic metastasis
#21320
high Confidence
Subject:
computed_tomography
(Imaging tests)
→
revealed
→
Object:
systemic_metastasis
(Disease phenotype)
Original: Computed tomography and positron emission tomography with fluorodeoxyglucose#revealed#systemic metastasis
#21319
high Confidence
Subject:
original_cytological_diagnosis
(Pathological diagnosis)
→
was
→
Object:
adenosquamous_carcinoma
(Tumor diseases)
Original: Original cytological diagnosis#was#adeno-squamous carcinoma
#21317
high Confidence
Subject:
cellular_EMC
(Tumor type)
→
exhibits
→
Object:
KIT_exon_13_mutation
(Gene mutation)
Original: cellular EMC#exhibits#EWSR1-NR4A3 fusion and KIT exon 13 mutations
#21316
high Confidence
Subject:
cellular_EMC
(Tumor type)
→
exhibits
→
Object:
EWSR1-NR4A3_fusion
(Gene fusion)
Original: cellular EMC#exhibits#EWSR1-NR4A3 fusion and KIT exon 13 mutations
#21314
high Confidence
Subject:
EWS-ATF1_fusion_transcript
(Gene fusion)
→
is_representative_of
→
Object:
t(12;22)_reciprocal_translocation
(Chromosomal translocation)
Original: EWS-ATF1 fusion transcripts#are representative of#t(12;22) clear cell sarcoma reciprocal translocation
#21298
high Confidence
Subject:
neuroendocrine_markers
(Molecular markers)
→
are_detected_in
→
Object:
gastric_signet-ring_cell_carcinoma
(Tumor type)
Original: The patient#was diagnosed with#mucin-negative gastric signet-ring cell carcinoma with neuroendocrine markers
#21271
high Confidence
Subject:
cystic_sebaceous_neoplasms
(Tumor type)
→
are_characterized_as
→
Object:
marker_lesions_of_Muir-Torre_syndrome
(Diagnostic markers)
Original: Cystic sebaceous neoplasms#are characterized as#marker lesions of Muir-Torre syndrome
#21265
high Confidence
Subject:
diagnosis_of_prostate_adenocarcinoma
(diagnosis)
→
is_based_on
→
Object:
supportive_features
(Auxiliary Features)
Original: diagnosis of prostate adenocarcinoma#is based on#multiple diagnostic criteria and supportive features
#21264
high Confidence
Subject:
diagnosis_of_prostate_adenocarcinoma
(diagnosis)
→
is_based_on
→
Object:
diagnostic_criteria
(Diagnostic criteria)
Original: diagnosis of prostate adenocarcinoma#is based on#multiple diagnostic criteria and supportive features
#21263
high Confidence
Subject:
pathological_intraluminal_secretions
(Pathological cavity secretions)
→
are_suspicious_for
→
Object:
prostate_cancer
(cancer)
Original: pathological intraluminal secretions#are suspicious for#prostate cancer
#21262
high Confidence
Subject:
histological_diagnosis_of_prostate_cancer
(Histological diagnosis)
→
1. Reliance
→
Object:
cytological_findings
(Cytological characteristics)
Original: histological diagnosis of prostate cancer#relies on#structural and cytological findings
#21261
high Confidence
Subject:
histological_diagnosis_of_prostate_cancer
(Histological diagnosis)
→
1. Reliance
→
Object:
structural_findings
(Structural features)
Original: histological diagnosis of prostate cancer#relies on#structural and cytological findings
#21260
high Confidence
Subject:
lymphoid_cells
(Immune cells)
→
are_positive_for
→
Object:
TIA-1
(Immune markers)
Original: Lymphoid cells#are positive for#CD3/ CD8/ granzymeB/ TIA-1
#21259
high Confidence
Subject:
lymphoid_cells
(Immune cells)
→
are_positive_for
→
Object:
granzymeB
(Immune markers)
Original: Lymphoid cells#are positive for#CD3/ CD8/ granzymeB/ TIA-1
#21258
high Confidence
Subject:
lymphoid_cells
(Immune cells)
→
are_positive_for
→
Object:
CD8
(Immune markers)
Original: Lymphoid cells#are positive for#CD3/ CD8/ granzymeB/ TIA-1
#21257
high Confidence
Subject:
lymphoid_cells
(Immune cells)
→
are_positive_for
→
Object:
CD3
(Immune markers)
Original: Lymphoid cells#are positive for#CD3/ CD8/ granzymeB/ TIA-1
#21253
high Confidence
Subject:
Immunohistochemistry
(Diagnostic techniques)
→
is_useful_for
→
Object:
sex_cord-stromal_tumor
(disease)
Original: immunohistochemistry#was useful in#confirming a sex cord-stromal tumor
#21251
high Confidence
Subject:
Immunoblastic_sarcoma
(Tumor)
→
classified_as
→
Object:
immunoblastic_sarcoma
(Tumor subtype)
Original: Tumors#classified as#"diffuse large lymphoid lymphomas with pyroninophilia" or "immunoblastic sarcomas"
#21250
high Confidence
Subject:
Diffuse_large_lymphoid_lymphoma
(Tumor)
→
classified_as
→
Object:
diffuse_large_lymphoid_lymphoma_with_pyroninophilia
(Tumor subtype)
Original: Tumors#classified as#"diffuse large lymphoid lymphomas with pyroninophilia" or "immunoblastic sarcomas"
#21249
high Confidence
Subject:
cells
(Tumor cells)
→
are_reactive_for
→
Object:
CD31
(protein)
Original: Cells#were reactive for#factor VIII-related antigen and CD31
#21248
high Confidence
Subject:
cells
(Tumor cells)
→
are_reactive_for
→
Object:
factor_VIII-related_antigen
(protein)
Original: Cells#were reactive for#factor VIII-related antigen and CD31
#21247
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
display
→
Object:
granzyme_B_negative_immunophenotype
(Immunophenotype)
Original: Tumor cells#displayed#CD3+/ CD8+/ CD4+/ TIA1+/ granzyme B(-) immunophenotype
#21246
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
display
→
Object:
TIA1_positive_immunophenotype
(Immunophenotype)
Original: Tumor cells#displayed#CD3+/ CD8+/ CD4+/ TIA1+/ granzyme B(-) immunophenotype
#21245
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
display
→
Object:
CD4_positive_immunophenotype
(Immunophenotype)
Original: Tumor cells#displayed#CD3+/ CD8+/ CD4+/ TIA1+/ granzyme B(-) immunophenotype
#21244
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
display
→
Object:
CD8_positive_immunophenotype
(Immunophenotype)
Original: Tumor cells#displayed#CD3+/ CD8+/ CD4+/ TIA1+/ granzyme B(-) immunophenotype
#21243
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
display
→
Object:
CD3_positive_immunophenotype
(Immunophenotype)
Original: Tumor cells#displayed#CD3+/ CD8+/ CD4+/ TIA1+/ granzyme B(-) immunophenotype
#21241
high Confidence
Subject:
hepatocellular_carcinoma (HCC)
(disease)
→
is_graded_using
→
Object:
modified_Edmondson_system
(Diagnostic Tools)
Original: Hepatocellular carcinoma (HCC)#is graded using#a modified Edmondson system (ES)
#21240
high Confidence
Subject:
Barrett's Esophagus (BE)
(disease)
→
is_recognized_by
→
Object:
goblet_cells
(Cell Type)
Original: BE#is recognized by#the presence of goblet cells within clusters of uniform columnar cells with vesicular nuclei
#21232
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
p63
(Transcription Factors)
Original: Tumor cells#are negative for#S100 and p63
#21231
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
S100
(Calcium Binding Protein)
Original: Tumor cells#are negative for#S100 and p63
#21230
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
vimentin
(Interstitial proteins)
Original: Tumor cells#are positive for#cytokeratin (AE1/AE3) and vimentin
#21229
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
cytokeratin_AE1/AE3
(Cytoskeletal proteins)
Original: Tumor cells#are positive for#cytokeratin (AE1/AE3) and vimentin
#21228
high Confidence
Subject:
TTF1
(Transcription Factors)
→
is_useful_in
→
Object:
diagnostic_metastatic_breast_carcinoma_to_thyroid
(Diagnostic Process)
Original: Immunomarkers/ such as GATA-3/ hormonal marker(s)/ PAX-8/ and TTF-1#may be useful in#diagnosing metastatic breast carcinoma to the thyroid
#21227
high Confidence
Subject:
PAX8
(Transcription Factors)
→
is_useful_in
→
Object:
diagnostic_metastatic_breast_carcinoma_to_thyroid
(Diagnostic Process)
Original: Immunomarkers/ such as GATA-3/ hormonal marker(s)/ PAX-8/ and TTF-1#may be useful in#diagnosing metastatic breast carcinoma to the thyroid
#21226
high Confidence
Subject:
GATA3
(Transcription Factors)
→
is_useful_in
→
Object:
diagnostic_metastatic_breast_carcinoma_to_thyroid
(Diagnostic Process)
Original: Immunomarkers/ such as GATA-3/ hormonal marker(s)/ PAX-8/ and TTF-1#may be useful in#diagnosing metastatic breast carcinoma to the thyroid
#21224
high Confidence
Subject:
FNA_biopsy
(Cytological detection technology)
→
diagnoses
→
Object:
LPA
(Disease phenotype)
Original: LPA#can be accurately diagnosed by#FNA biopsy
#21223
high Confidence
Subject:
ultrasound-guided needle biopsy
(Diagnostic techniques)
→
is_performed_in
→
Object:
prostatic carcinoma
(Tumor type)
Original: ultrasound-guided needle biopsies#were carried out in#50 clinically suspicious cases of prostatic carcinoma
#21222
high Confidence
Subject:
Immunohistochemical study
(Diagnostic techniques)
→
is_useful_for
→
Object:
diagnosis of rhabdomyosarcoma
(Diagnostic Process)
Original: immunohistochemical study#is useful for#diagnosis of rhabdomyosarcoma
#21221
high Confidence
Subject:
myoepithelial carcinoma
(Tumor type)
→
is_confirmed_by
→
Object:
smooth muscle actin
(protein)
Original: myoepithelial carcinoma#is confirmed by#positive immunohistochemical staining for S100 protein/ epithelial membrane antigen/ and smooth muscle actin
#21220
high Confidence
Subject:
myoepithelial carcinoma
(Tumor type)
→
is_confirmed_by
→
Object:
epithelial membrane antigen
(protein)
Original: myoepithelial carcinoma#is confirmed by#positive immunohistochemical staining for S100 protein/ epithelial membrane antigen/ and smooth muscle actin
#21219
high Confidence
Subject:
myoepithelial carcinoma
(Tumor type)
→
is_confirmed_by
→
Object:
S100 protein
(protein)
Original: myoepithelial carcinoma#is confirmed by#positive immunohistochemical staining for S100 protein/ epithelial membrane antigen/ and smooth muscle actin
#21217
high Confidence
Subject:
IDH2_R172_mutation
(Gene mutation)
→
occurs_in
→
Object:
large_cell_neuroendocrine_carcinoma
(Tumor type)
Original: IDH2 R172 mutations#occur in#sinonasal undifferentiated carcinoma (SNUC)/ large-cell neuroendocrine carcinoma (LCNEC)/ sinonasal adenocarcinomas/ and olfactory neuroblastoma (ONB)
#21216
high Confidence
Subject:
IDH2_R172_mutation
(Gene mutation)
→
occurs_in
→
Object:
sinonasal_undifferentiated_carcinoma
(Tumor type)
Original: IDH2 R172 mutations#occur in#sinonasal undifferentiated carcinoma (SNUC)/ large-cell neuroendocrine carcinoma (LCNEC)/ sinonasal adenocarcinomas/ and olfactory neuroblastoma (ONB)
#21215
high Confidence
Subject:
triple_negative_breast_cancer
(Tumor type)
→
is_negative_for
→
Object:
HER2
(Receptor protein)
Original: Triple-negative breast cancer (TNBC)#is negative for#HER2
#21214
high Confidence
Subject:
triple_negative_breast_cancer
(Tumor type)
→
lacks
→
Object:
progesterone_receptor
(Receptor protein)
Original: Triple-negative breast cancer (TNBC)#lacks#estrogen and progesterone receptors
#21213
high Confidence
Subject:
triple_negative_breast_cancer
(Tumor type)
→
lacks
→
Object:
estrogen_receptor
(Receptor protein)
Original: Triple-negative breast cancer (TNBC)#lacks#estrogen and progesterone receptors
#21212
high Confidence
Subject:
prostatic_carcinoma
(disease)
→
showed
→
Object:
prostatic_acid_phosphatase
(protein)
Original: Prostatic carcinoma cases#showed#PSA and prostatic acid phosphatase immunoreactivity
#21211
high Confidence
Subject:
prostatic_carcinoma
(disease)
→
showed
→
Object:
PSA
(protein)
Original: Prostatic carcinoma cases#showed#PSA and prostatic acid phosphatase immunoreactivity
#21210
high Confidence
Subject:
histological_ultrastructural_and_immunohistochemical_features
(Diagnosis)
→
are_essential_for
→
Object:
diagnosis
(diagnosis)
Original: Histological/ ultrastructural/ and immunohistochemical features#are essential for#diagnosis
#21209
high Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
was_based_on
→
Object:
cytological_features_of_tumor_cells
(Cell morphology)
Original: differential diagnosis#was based on#cytological features of tumor cells
#21206
high Confidence
Subject:
Malignant_granular_cell_tumor
(Tumor type)
→
was_diagnosed_using
→
Object:
histological_criteria_by_Fanburg-Smith
(Diagnostic criteria)
Original: Malignant granular cell tumor#was diagnosed using#histological criteria established by Fanburg-Smith et al.
#21205
high Confidence
Subject:
immunohistochemical_finding
(Immunohistochemical findings)
→
led_to
→
Object:
diagnosis_of_borderline_clear_cell_adenofibroma
(Diagnosis conclusion)
Original: Characteristic morphologic and immunohistochemical findings#led to#a diagnosis of borderline clear cell adenofibroma
#21204
high Confidence
Subject:
morphologic_finding
(Morphological findings)
→
led_to
→
Object:
diagnosis_of_borderline_clear_cell_adenofibroma
(Diagnosis conclusion)
Original: Characteristic morphologic and immunohistochemical findings#led to#a diagnosis of borderline clear cell adenofibroma
#21203
high Confidence
Subject:
CT_scan
(Imaging Technology)
→
shows
→
Object:
right_ovarian_mass
(Lump)
Original: Ultrasound and CT scans#showed#a right ovarian mass 8 cm in diameter
#21202
high Confidence
Subject:
ultrasound
(Imaging Technology)
→
shows
→
Object:
right_ovarian_mass
(Lump)
Original: Ultrasound and CT scans#showed#a right ovarian mass 8 cm in diameter
#21201
high Confidence
Subject:
tumor
(Tumor type)
→
shows_strong_immunoreactivity_for
→
Object:
neuron_specific_enolase
(Enzymes)
Original: Tumors#showed#strong immunoreactivity for neuron-specific enolase
#21200
high Confidence
Subject:
ductal_carcinoma_in_situ
(Tumor type)
→
is_characterized_by
→
Object:
cribriform_pattern
(Organizational Structure)
Original: Ductal carcinoma in situ#is characterized by#small and uniform tumor cells growing in a cribriform pattern without comedo necrosis
#21199
high Confidence
Subject:
ductal_carcinoma_in_situ
(Tumor type)
→
is_characterized_by
→
Object:
small_uniform_tumor_cells
(Cell morphology)
Original: Ductal carcinoma in situ#is characterized by#small and uniform tumor cells growing in a cribriform pattern without comedo necrosis
#21198
high Confidence
Subject:
immunohistochemical_technique
(Detection Technology)
→
assists_in
→
Object:
differential_diagnosis_of_MRT
(Diagnosis conclusion)
Original: Immunohistochemical techniques#assist in#differential diagnosis of MRT against other childhood round-cell tumors
#21197
high Confidence
Subject:
immunohistochemical_pattern
(Detection Mode)
→
permits
→
Object:
diagnosis_of_MRT
(Diagnosis conclusion)
Original: Immunohistochemical pattern#permits#a confident diagnosis of MRT
#21196
high Confidence
Subject:
hyaline_inclusions
(Cell structure)
→
are_negative_for
→
Object:
alpha_1_antichymotrypsin
(Protease inhibitors)
Original: Hyaline inclusions#are positive for#vimentin and keratin/ but negative with desmin/ S-100 protein/ NSE/ myoglobin/ LCA/ alpha-1-antichymotrypsin
#21195
high Confidence
Subject:
hyaline_inclusions
(Cell structure)
→
are_negative_for
→
Object:
LCA
(common leukocyte antigen)
Original: Hyaline inclusions#are positive for#vimentin and keratin/ but negative with desmin/ S-100 protein/ NSE/ myoglobin/ LCA/ alpha-1-antichymotrypsin
#21194
high Confidence
Subject:
hyaline_inclusions
(Cell structure)
→
are_negative_for
→
Object:
myoglobin
(Cytoskeletal proteins)
Original: Hyaline inclusions#are positive for#vimentin and keratin/ but negative with desmin/ S-100 protein/ NSE/ myoglobin/ LCA/ alpha-1-antichymotrypsin
#21193
high Confidence
Subject:
hyaline_inclusions
(Cell structure)
→
are_negative_for
→
Object:
NSE
(Neuron-specific enolase)
Original: Hyaline inclusions#are positive for#vimentin and keratin/ but negative with desmin/ S-100 protein/ NSE/ myoglobin/ LCA/ alpha-1-antichymotrypsin
#21192
high Confidence
Subject:
hyaline_inclusions
(Cell structure)
→
are_negative_for
→
Object:
S-100_protein
(Cytoskeletal proteins)
Original: Hyaline inclusions#are positive for#vimentin and keratin/ but negative with desmin/ S-100 protein/ NSE/ myoglobin/ LCA/ alpha-1-antichymotrypsin
#21191
high Confidence
Subject:
hyaline_inclusions
(Cell structure)
→
are_negative_for
→
Object:
desmin
(Cytoskeletal proteins)
Original: Hyaline inclusions#are positive for#vimentin and keratin/ but negative with desmin/ S-100 protein/ NSE/ myoglobin/ LCA/ alpha-1-antichymotrypsin
#21190
high Confidence
Subject:
hyaline_inclusions
(Cell structure)
→
are_positive_for
→
Object:
keratin
(Cytoskeletal proteins)
Original: Hyaline inclusions#are positive for#vimentin and keratin/ but negative with desmin/ S-100 protein/ NSE/ myoglobin/ LCA/ alpha-1-antichymotrypsin
#21189
high Confidence
Subject:
hyaline_inclusions
(Cell structure)
→
are_positive_for
→
Object:
vimentin
(Cytoskeletal proteins)
Original: Hyaline inclusions#are positive for#vimentin and keratin/ but negative with desmin/ S-100 protein/ NSE/ myoglobin/ LCA/ alpha-1-antichymotrypsin
#21188
high Confidence
Subject:
Pancreatic_tumor
(Tumor type)
→
exhibits
→
Object:
Papillary-cystic_microscopic_morphology
(Histological morphology)
Original: Unusual pancreatic tumor#exhibits#a characteristic papillary-cystic microscopic morphology
#21185
high Confidence
Subject:
lung_adenocarcinoma
(disease)
→
is_diagnosed_by
→
Object:
cytologic_methods
(Diagnostic techniques)
Original: Lung adenocarcinomas#are diagnosed by#cytologic methods
#21184
high Confidence
Subject:
ACD-associated_RCC
(disease)
→
is_recognized_as
→
Object:
distinct_entity
(Disease classification)
Original: ACD-associated RCC#is recognized as#a distinct entity
#21181
high Confidence
Subject:
Lacunar type Reed-Sternberg cells
(Cell Type)
→
are_positive_for
→
Object:
CD15
(Protein markers)
Original: Lacunar type Reed-Sternberg cells#were positive for#CD30 and CD15
#21180
high Confidence
Subject:
Lacunar type Reed-Sternberg cells
(Cell Type)
→
are_positive_for
→
Object:
CD30
(Protein markers)
Original: Lacunar type Reed-Sternberg cells#were positive for#CD30 and CD15
#21179
high Confidence
Subject:
Cells
(cell)
→
were_negative_for
→
Object:
terminal_deoxynucleotidyl_transferase
(Enzymes)
Original: Cells#were negative for#CD34 and terminal deoxynucleotidyl transferase
#21178
high Confidence
Subject:
Cells
(cell)
→
were_negative_for
→
Object:
CD34
(Cell surface markers)
Original: Cells#were negative for#CD34 and terminal deoxynucleotidyl transferase
#21177
high Confidence
Subject:
Cells
(cell)
→
were_positive_for
→
Object:
CD20
(Cell surface markers)
Original: Cells#were positive for#CD19/ CD22/ and low-density CD20
#21176
high Confidence
Subject:
Cells
(cell)
→
were_positive_for
→
Object:
CD22
(Cell surface markers)
Original: Cells#were positive for#CD19/ CD22/ and low-density CD20
#21175
high Confidence
Subject:
Cells
(cell)
→
were_positive_for
→
Object:
CD19
(Cell surface markers)
Original: Cells#were positive for#CD19/ CD22/ and low-density CD20
#21174
high Confidence
Subject:
Fine_needle_aspiration_cytology
(Diagnostic techniques)
→
diagnosis_of
→
Object:
granular_cell_tumor
(Tumor diseases)
Original: Fine needle aspiration cytology (FNAC)#diagnosis of#granular cell tumor (GCT)
#21173
high Confidence
Subject:
HHV-8
(Virus)
→
was_proven_by
→
Object:
immunocytochemistry
(Diagnostic techniques)
Original: Positivity for HHV-8#was proven by#immunocytochemistry
#21161
high Confidence
Subject:
ghost_cells
(Tumor cells)
→
presence_in_FNA_smears_is_sufficient_for
→
Object:
confident_cytologic_diagnosis_of_pilomatrixoma
(Diagnosis conclusion)
Original: presence of basaloid cells and ghost cells in FNA smears#was sufficient for#a confident cytologic diagnosis of pilomatrixoma
#21160
high Confidence
Subject:
basaloid_cells
(Tumor cells)
→
presence_in_FNA_smears_is_sufficient_for
→
Object:
confident_cytologic_diagnosis_of_pilomatrixoma
(Diagnosis conclusion)
Original: presence of basaloid cells and ghost cells in FNA smears#was sufficient for#a confident cytologic diagnosis of pilomatrixoma
#21159
high Confidence
Subject:
multilobated_and_ground-glass_nuclei
(Nuclear morphology)
→
is_marker_of
→
Object:
thyroid_papillary_carcinoma
(Tumor diseases)
Original: The presence of multilobated and ground-glass nuclei#is#a typical histological marker of thyroid papillary carcinoma
#21149
high Confidence
Subject:
tumor_cells
(Cell Type)
→
stained_with
→
Object:
anti_NSE_polyclonal_antibody
(Antibody)
Original: Tumor cells#stained with#anti-NSE polyclonal antibody
#21148
high Confidence
Subject:
tumor_cells
(Cell Type)
→
stained_negative_for
→
Object:
CD45_RO
(Protein molecules)
Original: Tumor cells#stained positive for#CD20 but not for CD45 RO
#21147
high Confidence
Subject:
tumor_cells
(Cell Type)
→
stained_positive_for
→
Object:
CD20
(Protein molecules)
Original: Tumor cells#stained positive for#CD20 but not for CD45 RO
#21146
high Confidence
Subject:
special_histopathological_staining
(Detection Technology)
→
demonstrated
→
Object:
small_yeast_cells_with_narrow_base_budding
(microorganism)
Original: Special histopathological staining#demonstrated#the presence of small yeast cells with simple and narrow-base budding compatible with Sporothrix schenckii
#21130
high Confidence
Subject:
MYB-NFIB_translocation
(Gene fusion)
→
is_common_in
→
Object:
ACC
(Tumor type)
Original: MYB-NFIB translocation#is common in#ACC
#21121
high Confidence
Subject:
nine_cytologic_features
(Cytological characteristics)
→
are_significantly_associated_with
→
Object:
HCC
(disease)
Original: Nine cytologic features#are significantly associated with#HCC
#21120
high Confidence
Subject:
stepwise_logistic_regression_analysis
(Statistical analysis methods)
→
selects
→
Object:
useful_cytologic_features_for_discriminating_HCC
(Diagnostic features)
Original: Step-wise logistic regression analysis#selects#useful cytologic features for discriminating HCC
#21119
high Confidence
Subject:
fine_needle_aspiration_smears
(Cytological testing methods)
→
are_used_to_detect
→
Object:
cytologic_changes_associated_with_HCC
(Cytological changes)
Original: Fine needle aspiration (FNA) smears#are used to detect#cytologic changes associated with HCC
#21118
high Confidence
Subject:
epithelial_cells
(Epithelial cells)
→
are_stained_with
→
Object:
antibodies_against_cytokeratin
(Antibody staining)
Original: Epithelial cells#were stained with#antibodies against vimentin and cytokeratin
#21117
high Confidence
Subject:
epithelial_cells
(Epithelial cells)
→
are_stained_with
→
Object:
antibodies_against_vimentin
(Antibody staining)
Original: Epithelial cells#were stained with#antibodies against vimentin and cytokeratin
#21116
high Confidence
Subject:
epithelial_cells
(Epithelial cells)
→
are_nonimmunoreactive_for
→
Object:
parathyroid_hormone
(hormone)
Original: Epithelial cells#were immunoreactive for#cytokeratin and nonimmunoreactive for vimentin/ S-100/ chromogranin/ and parathyroid hormone
#21115
high Confidence
Subject:
epithelial_cells
(Epithelial cells)
→
are_nonimmunoreactive_for
→
Object:
Chromogranin
(Secretory granule protein)
Original: Epithelial cells#were immunoreactive for#cytokeratin and nonimmunoreactive for vimentin/ S-100/ chromogranin/ and parathyroid hormone
#21114
high Confidence
Subject:
epithelial_cells
(Epithelial cells)
→
are_nonimmunoreactive_for
→
Object:
S-100
(Calcium Binding Protein)
Original: Epithelial cells#were immunoreactive for#cytokeratin and nonimmunoreactive for vimentin/ S-100/ chromogranin/ and parathyroid hormone
#21113
high Confidence
Subject:
epithelial_cells
(Epithelial cells)
→
are_nonimmunoreactive_for
→
Object:
vimentin
(Structural proteins)
Original: Epithelial cells#were immunoreactive for#cytokeratin and nonimmunoreactive for vimentin/ S-100/ chromogranin/ and parathyroid hormone
#21112
high Confidence
Subject:
epithelial_cells
(Epithelial cells)
→
are_immunoreactive_for
→
Object:
cytokeratin
(Structural proteins)
Original: Epithelial cells#were immunoreactive for#cytokeratin and nonimmunoreactive for vimentin/ S-100/ chromogranin/ and parathyroid hormone
#21110
high Confidence
Subject:
cell_block_sections
(Pathological technology)
→
provide
→
Object:
histologic_confirmation
(Diagnosis confirmation)
Original: Cell block sections#provide#histologic confirmation
#21109
high Confidence
Subject:
Neuroendocrine_differentiation_in_LCNEC
(Differentiation characteristics)
→
was_confirmed_by
→
Object:
immunohistochemistry_for_CD56
(Immunohistochemistry)
Original: Neuroendocrine differentiation in LCNEC#was confirmed by#immunohistochemistry for synaptophysin and CD56
#21108
high Confidence
Subject:
Neuroendocrine_differentiation_in_LCNEC
(Differentiation characteristics)
→
was_confirmed_by
→
Object:
immunohistochemistry_for_synaptophysin
(Immunohistochemistry)
Original: Neuroendocrine differentiation in LCNEC#was confirmed by#immunohistochemistry for synaptophysin and CD56
#21107
high Confidence
Subject:
Histologic_examination
(Pathological technology)
→
revealed
→
Object:
LCNEC
(Tumor type)
Original: Histologic examination#revealed#LCNEC with minor foci of SmCC
#21106
high Confidence
Subject:
Uterine_endometrium_curettage
(Pathological technology)
→
revealed
→
Object:
endometrioid_adenocarcinoma
(Tumor type)
Original: Uterine endometrium curettage#revealed#endometrioid adenocarcinoma with squamous differentiation
#21096
high Confidence
Subject:
final_diagnosis
(Diagnosis conclusion)
→
is
→
Object:
miscellaneous
(other)
Original: final diagnoses#were#cancer (69%)/ benign (13%)/ atypical but not diagnostic (10%)/ high-grade PIN (5%)/ miscellaneous (3%)
#21095
high Confidence
Subject:
final_diagnosis
(Diagnosis conclusion)
→
is
→
Object:
high-grade_PIN
(High-grade prostatic intraepithelial neoplasia)
Original: final diagnoses#were#cancer (69%)/ benign (13%)/ atypical but not diagnostic (10%)/ high-grade PIN (5%)/ miscellaneous (3%)
#21094
high Confidence
Subject:
final_diagnosis
(Diagnosis conclusion)
→
is
→
Object:
atypical_condition
(Atypical diseases)
Original: final diagnoses#were#cancer (69%)/ benign (13%)/ atypical but not diagnostic (10%)/ high-grade PIN (5%)/ miscellaneous (3%)
#21093
high Confidence
Subject:
final_diagnosis
(Diagnosis conclusion)
→
is
→
Object:
benign_condition
(Benign diseases)
Original: final diagnoses#were#cancer (69%)/ benign (13%)/ atypical but not diagnostic (10%)/ high-grade PIN (5%)/ miscellaneous (3%)
#21092
high Confidence
Subject:
final_diagnosis
(Diagnosis conclusion)
→
is
→
Object:
cancer
(disease)
Original: final diagnoses#were#cancer (69%)/ benign (13%)/ atypical but not diagnostic (10%)/ high-grade PIN (5%)/ miscellaneous (3%)
#21091
high Confidence
Subject:
Neoplastic_cells
(Tumor cells)
→
are_positive_to
→
Object:
Alpha-actin
(Cytoskeletal proteins)
Original: Neoplastic cells#were positive to#vimentin/ actin/ and alpha-actin
#21090
high Confidence
Subject:
Neoplastic_cells
(Tumor cells)
→
are_positive_to
→
Object:
Actin
(Cytoskeletal proteins)
Original: Neoplastic cells#were positive to#vimentin/ actin/ and alpha-actin
#21089
high Confidence
Subject:
Neoplastic_cells
(Tumor cells)
→
are_positive_to
→
Object:
Vimentin
(Cytoskeletal proteins)
Original: Neoplastic cells#were positive to#vimentin/ actin/ and alpha-actin
#21078
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
tested_positive_for
→
Object:
STAT6
(Transcription Factors)
Original: tumor cells#tested positive for#STAT6
#21073
high Confidence
Subject:
urinary_cytology
(Cytology)
→
is_accepted_as
→
Object:
diagnostic_tool_in_bladder_cancer
(Diagnostic Tools)
Original: urinary cytology#is accepted#as a diagnostic tool in bladder cancer detection
#21070
high Confidence
Subject:
PD-L1_expression
(Protein expression)
→
is_associated_with
→
Object:
clinicopathological_characteristics
(Disease phenotype)
Original: Relationships between PD-L1 expression#and#clinicopathological characteristics
#21064
high Confidence
Subject:
Rosai-Dorfman_disease
(disease)
→
is_classified_as
→
Object:
histiocytic_neoplasm
(disease)
Original: Rosai-Dorfman disease#is classified as#a histiocytic neoplasm
#21063
high Confidence
Subject:
Nuclear_pseudoinclusions
(Nuclear morphology)
→
is_hallmark_of
→
Object:
papillary_thyroid_carcinoma
(Tumor type)
Original: Fine chromatin/ nuclear grooves/ and nuclear pseudoinclusions#are hallmarks of diagnosis in#papillary thyroid carcinoma
#21062
high Confidence
Subject:
Nuclear_grooves
(Nuclear morphology)
→
is_hallmark_of
→
Object:
papillary_thyroid_carcinoma
(Tumor type)
Original: Fine chromatin/ nuclear grooves/ and nuclear pseudoinclusions#are hallmarks of diagnosis in#papillary thyroid carcinoma
#21061
high Confidence
Subject:
Fine_chromatin
(Nuclear chromatin morphology)
→
is_hallmark_of
→
Object:
papillary_thyroid_carcinoma
(Tumor type)
Original: Fine chromatin/ nuclear grooves/ and nuclear pseudoinclusions#are hallmarks of diagnosis in#papillary thyroid carcinoma
#21053
high Confidence
Subject:
molecular_genotyping
(Molecular testing)
→
revealed
→
Object:
HPV_type_42_positivity
(Viral infection)
Original: Molecular genotyping#revealed#positivity for HPV type 42
#21052
high Confidence
Subject:
follow-up_biopsies
(Histological examination)
→
revealed
→
Object:
malignancy
(Malignant tumors)
Original: Follow-up biopsies#revealed#malignancy in 46 patients (51.69%)
#21051
high Confidence
Subject:
pyloric_gland_adenoma
(Tumor)
→
is
→
Object:
rare_neoplasm_of_gastrointestinal_tract
(Disease phenotype)
Original: Pyloric gland adenomas#are rare neoplasms of#the gastrointestinal tract
#21050
high Confidence
Subject:
diagnostic_criteria
(Diagnostic criteria)
→
are_well_established_for
→
Object:
separation_of_neoplasms
(Diagnostic strategy)
Original: Criteria#are well established for#separation of nodular goiter from most neoplasms
#21049
high Confidence
Subject:
diagnostic_criteria
(Diagnostic criteria)
→
are_well_established_for
→
Object:
separation_of_nodular_goiter
(Diagnostic strategy)
Original: Criteria#are well established for#separation of nodular goiter from most neoplasms
#21045
high Confidence
Subject:
neoplasm
(Tumor tissue)
→
stains_positively_for
→
Object:
Vs38C
(Cell surface antigens)
Original: neoplasm#stains positively for#CD45/ CD38/ MUM1/ and Vs38C
#21044
high Confidence
Subject:
neoplasm
(Tumor tissue)
→
stains_positively_for
→
Object:
MUM1
(Transcription Factors)
Original: neoplasm#stains positively for#CD45/ CD38/ MUM1/ and Vs38C
#21043
high Confidence
Subject:
neoplasm
(Tumor tissue)
→
stains_positively_for
→
Object:
CD38
(Cell surface antigens)
Original: neoplasm#stains positively for#CD45/ CD38/ MUM1/ and Vs38C
#21042
high Confidence
Subject:
neoplasm
(Tumor tissue)
→
stains_positively_for
→
Object:
CD45
(Cell surface antigens)
Original: neoplasm#stains positively for#CD45/ CD38/ MUM1/ and Vs38C
#21036
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_immunoreactive_to
→
Object:
vimentin
(Intermediate filament protein)
Original: tumor cells#were immunoreactive to#cytokeratin/ calretinin/ epithelial membrane antigen (EMA)/ CA-125/ and vimentin
#21035
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_immunoreactive_to
→
Object:
CA-125
(Carbohydrate antigen)
Original: tumor cells#were immunoreactive to#cytokeratin/ calretinin/ epithelial membrane antigen (EMA)/ CA-125/ and vimentin
#21034
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_immunoreactive_to
→
Object:
EMA
(ECMA)
Original: tumor cells#were immunoreactive to#cytokeratin/ calretinin/ epithelial membrane antigen (EMA)/ CA-125/ and vimentin
#21033
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_immunoreactive_to
→
Object:
calretinin
(Calcium Binding Protein)
Original: tumor cells#were immunoreactive to#cytokeratin/ calretinin/ epithelial membrane antigen (EMA)/ CA-125/ and vimentin
#21032
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_immunoreactive_to
→
Object:
cytokeratin
(Cytoskeletal proteins)
Original: tumor cells#were immunoreactive to#cytokeratin/ calretinin/ epithelial membrane antigen (EMA)/ CA-125/ and vimentin
#21014
high Confidence
Subject:
PSA
(Protein markers)
→
shows_positivity_in
→
Object:
tumor_cells
(Tumor cells)
Original: Positivity for PSA#was demonstrated by#immunocytochemical stain in tumor cells
#21013
high Confidence
Subject:
cytokeratin_20
(Protein markers)
→
shows_positivity_in
→
Object:
prostate_cancer
(Tumor diseases)
Original: In 2 cases/ there#was#negative staining for PSA and cytokeratin 7/ and positivity for cytokeratin 20
#21012
high Confidence
Subject:
cytokeratin_7
(Protein markers)
→
shows_negative_stain_in
→
Object:
prostate_cancer
(Tumor diseases)
Original: In 2 cases/ there#was#negative staining for PSA and cytokeratin 7/ and positivity for cytokeratin 20
#21011
high Confidence
Subject:
PSA
(Protein markers)
→
shows_negative_stain_in
→
Object:
prostate_cancer
(Tumor diseases)
Original: In 2 cases/ there#was#negative staining for PSA and cytokeratin 7/ and positivity for cytokeratin 20
#21010
high Confidence
Subject:
racemase
(Enzymes)
→
shows_positivity_in
→
Object:
prostate_cancer
(Tumor diseases)
Original: Immunohistochemical results#further mimicked#prostate cancer with negative stains for basal cell markers and positive stains for racemase
#21009
high Confidence
Subject:
p63
(Protein markers)
→
shows_negative_stain_in
→
Object:
prostate_cancer
(Tumor diseases)
Original: Immunohistochemical results#further mimicked#prostate cancer with negative stains for basal cell markers and positive stains for racemase
#21008
high Confidence
Subject:
high-molecular_weight_cytokeratin
(Protein markers)
→
shows_negative_stain_in
→
Object:
prostate_cancer
(Tumor diseases)
Original: Immunohistochemical results#further mimicked#prostate cancer with negative stains for basal cell markers and positive stains for racemase
#21007
high Confidence
Subject:
S-100_protein
(Protein markers)
→
shows_positivity_in
→
Object:
malignant_melanoma_of_the_esophagus
(Tumor diseases)
Original: The immunohistochemical study#revealed#positivity for HMB-45 and S-100 protein
#21006
high Confidence
Subject:
HMB-45
(Protein markers)
→
shows_positivity_in
→
Object:
malignant_melanoma_of_the_esophagus
(Tumor diseases)
Original: The immunohistochemical study#revealed#positivity for HMB-45 and S-100 protein
#21003
high Confidence
Subject:
CD56
(Cell adhesion molecules)
→
shows_positive_reaction
→
Object:
Immunohistochemistry
(Detection Methods)
Original: immunohistochemical study#revealed#positive reaction for KIT/ PDGFRA/ synaptophysin/ and CD56
#21002
high Confidence
Subject:
PDGFRA
(Receptor tyrosine kinases)
→
shows_positive_reaction
→
Object:
Immunohistochemistry
(Detection Methods)
Original: immunohistochemical study#revealed#positive reaction for KIT/ PDGFRA/ synaptophysin/ and CD56
#21001
high Confidence
Subject:
KIT
(Receptor tyrosine kinases)
→
shows_positive_reaction
→
Object:
Immunohistochemistry
(Detection Methods)
Original: immunohistochemical study#revealed#positive reaction for KIT/ PDGFRA/ synaptophysin/ and CD56
#20996
high Confidence
Subject:
fine-needle_aspiration_biopsy
(Diagnostic techniques)
→
is_performed_on
→
Object:
adenoid_cystic_carcinoma_of_breast
(Tumor type)
Original: Fine-needle aspiration biopsy#is performed on#adenoid cystic carcinoma of the breast
#20991
high Confidence
Subject:
tumor
(Tumor)
→
diagnosed_as
→
Object:
anaplastic_ependymoma
(Tumor type)
Original: tumor#was diagnosed as#anaplastic ependymoma
#20974
high Confidence
Subject:
Medullary_thyroid_carcinoma
(Tumor type)
→
is
→
Object:
rare_neuroendocrine_thyroid_neoplasm
(Disease phenotype)
Original: Medullary thyroid carcinoma#is#a rare neuroendocrine thyroid neoplasm
#20973
high Confidence
Subject:
Immunohistochemistry
(Detection Technology)
→
detects
→
Object:
S-100_protein
(protein)
Original: immunohistochemistry#detected#vimentin/ S-100 protein/ and other markers
#20972
high Confidence
Subject:
Immunohistochemistry
(Detection Technology)
→
detects
→
Object:
vimentin
(protein)
Original: immunohistochemistry#detected#vimentin/ S-100 protein/ and other markers
#20971
high Confidence
Subject:
ependymoma
(Tumor type)
→
is_included_in
→
Object:
WHO_classification_of_nervous_system
(Disease classification criteria)
Original: clear cell ependymoma#was included in#WHO classification of nervous system
#20966
high Confidence
Subject:
prominent_nucleoli
(Nuclear characteristics)
→
is_characteristic_of
→
Object:
melanoma
(Tumor)
Original: melanoma#is characterized by#large pleomorphic cells with eosinophilic cytoplasm/ prominent nucleoli/ and S100 protein
#20965
high Confidence
Subject:
eosinophilic_cytoplasm
(Cytoplasmic characteristics)
→
is_characteristic_of
→
Object:
melanoma
(Tumor)
Original: melanoma#is characterized by#large pleomorphic cells with eosinophilic cytoplasm/ prominent nucleoli/ and S100 protein
#20964
high Confidence
Subject:
large_pleomorphic_cells
(Tumor cell subtype)
→
are_characteristic_of
→
Object:
melanoma
(Tumor)
Original: melanoma#is characterized by#large pleomorphic cells with eosinophilic cytoplasm/ prominent nucleoli/ and S100 protein
#20957
high Confidence
Subject:
diagnosis
(Diagnosis conclusion)
→
was_made_as
→
Object:
diffuse_medium_sized_non-Hodgkin's_lymphoma_B-cell_type
(Tumor type)
Original: A diagnosis#was made as#diffuse/ medium-sized non-Hodgkin's lymphoma/ B-cell type
#20955
high Confidence
Subject:
p53_protein
(Transcription Factors)
→
is_demonstrated_in
→
Object:
basaloid_squamous_cell_carcinoma
(Tumor type)
Original: p53 protein#was demonstrated#in basaloid squamous cell carcinoma
#20954
high Confidence
Subject:
basaloid_squamous_cell_carcinoma
(Tumor type)
→
is_characterized_as
→
Object:
variant_of_squamous_cell_carcinoma
(Tumor type)
Original: basaloid squamous cell carcinoma (BSCC)#is characterized as#a variant of squamous cell carcinoma
#20953
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
S100
(Calcium Binding Protein)
Original: tumor cells#were positive for#MITF and S-100
#20952
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
MITF
(Transcription Factors)
Original: tumor cells#were positive for#MITF and S-100
#20951
high Confidence
Subject:
malignant_melanoma
(Tumor phenotype)
→
diagnosed_by
→
Object:
immunohistochemical_examination
(Diagnostic techniques)
Original: malignant melanoma#was diagnosed#after immunohistochemical examination
#20950
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
show_strong_positive_staining_for
→
Object:
c-KIT
(Protein markers)
Original: Tumor cells#exhibit#strong positive staining for HMB-45 and c-KIT
#20949
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
show_strong_positive_staining_for
→
Object:
HMB-45
(Protein markers)
Original: Tumor cells#exhibit#strong positive staining for HMB-45 and c-KIT
#20948
high Confidence
Subject:
FDC
(Follicular dendritic cells)
→
highlighted_by
→
Object:
CD35
(Cell surface markers)
Original: FDC#highlighted by#CD21/ CD35/ R4/23/ Ki-M4/ CNA.42/ CD68
#20947
high Confidence
Subject:
FDC
(Follicular dendritic cells)
→
highlighted_by
→
Object:
CD21
(Cell surface markers)
Original: FDC#highlighted by#CD21/ CD35/ R4/23/ Ki-M4/ CNA.42/ CD68
#20946
high Confidence
Subject:
tumor
(Tumor tissue)
→
diagnosed_as
→
Object:
pituitary_carcinoma
(disease)
Original: Tumor#was diagnosed as#pituitary carcinoma from pars intermedia cells
#20940
high Confidence
Subject:
immunocytochemical_stains
(Detection Technology)
→
revealed
→
Object:
cytokeratin_negativity
(Protein expression)
Original: Immunocytochemical stains#revealed#S-100 and vimentin positivity/ while actin/ myoglobin/ and cytokeratin stains were negative
#20939
high Confidence
Subject:
immunocytochemical_stains
(Detection Technology)
→
revealed
→
Object:
myoglobin_negativity
(Protein expression)
Original: Immunocytochemical stains#revealed#S-100 and vimentin positivity/ while actin/ myoglobin/ and cytokeratin stains were negative
#20938
high Confidence
Subject:
immunocytochemical_stains
(Detection Technology)
→
revealed
→
Object:
actin_negativity
(Protein expression)
Original: Immunocytochemical stains#revealed#S-100 and vimentin positivity/ while actin/ myoglobin/ and cytokeratin stains were negative
#20937
high Confidence
Subject:
immunocytochemical_stains
(Detection Technology)
→
revealed
→
Object:
vimentin_positivity
(Protein expression)
Original: Immunocytochemical stains#revealed#S-100 and vimentin positivity/ while actin/ myoglobin/ and cytokeratin stains were negative
#20936
high Confidence
Subject:
immunocytochemical_stains
(Detection Technology)
→
revealed
→
Object:
S-100_positivity
(Protein expression)
Original: Immunocytochemical stains#revealed#S-100 and vimentin positivity/ while actin/ myoglobin/ and cytokeratin stains were negative
#20932
high Confidence
Subject:
Cytopathologic_diagnosis_by_FNA
(Diagnostic techniques)
→
is_imperative_for
→
Object:
Primary_pancreatic_lymphomas
(Tumor diseases)
Original: Cytopathologic diagnosis by FNA#is imperative for#primary pancreatic lymphomas
#20931
high Confidence
Subject:
hyperlobation
(Nuclear structure)
→
is_consistent_with
→
Object:
papillary_thyroid_carcinoma
(disease)
Original: Neoplastic follicular cell nuclei#were divided into#grooves/ pseudoinclusions/ and hyperlobation consistent with papillary thyroid carcinoma
#20930
high Confidence
Subject:
pseudoinclusions
(Nuclear structure)
→
are_consistent_with
→
Object:
papillary_thyroid_carcinoma
(disease)
Original: Neoplastic follicular cell nuclei#were divided into#grooves/ pseudoinclusions/ and hyperlobation consistent with papillary thyroid carcinoma
#20929
high Confidence
Subject:
grooves
(Nuclear structure)
→
are_consistent_with
→
Object:
papillary_thyroid_carcinoma
(disease)
Original: Neoplastic follicular cell nuclei#were divided into#grooves/ pseudoinclusions/ and hyperlobation consistent with papillary thyroid carcinoma
#20926
high Confidence
Subject:
tumor_sample
(Tumor samples)
→
positive_for
→
Object:
CD34
(Molecular markers)
Original: Immunohistochemical markers#were positive for#Factor VIII antigen/ CD31/ and CD34
#20925
high Confidence
Subject:
tumor_sample
(Tumor samples)
→
positive_for
→
Object:
CD31
(Molecular markers)
Original: Immunohistochemical markers#were positive for#Factor VIII antigen/ CD31/ and CD34
#20924
high Confidence
Subject:
tumor_sample
(Tumor samples)
→
positive_for
→
Object:
Factor_VIII_antigen
(Molecular markers)
Original: Immunohistochemical markers#were positive for#Factor VIII antigen/ CD31/ and CD34
#20915
high Confidence
Subject:
avidin-biotin-complex_immunoperoxidase_method
(Immunohistochemistry)
→
is_used_for
→
Object:
staining
(dyeing)
Original: avidin-biotin-complex immunoperoxidase method#is used for#staining
#20914
high Confidence
Subject:
anticyclin_monoclonal_antibody
(Monoclonal antibodies)
→
is_used_to
→
Object:
survey_cyclin_expression_in_cytologic_preparations
(Protein expression detection)
Original: anticyclin monoclonal antibody#is used to#survey cyclin expression in cytologic preparations
#20913
high Confidence
Subject:
EMA
(Epithelial membrane antigen)
→
shows
→
Object:
immunohistochemistry_positivity
(Immunohistochemistry results)
Original: pan-cytokeratin AE1/AE3 and EMA#show#positivity in immunohistochemistry
#20912
high Confidence
Subject:
pan-cytokeratin_AE1/AE3
(Cytoskeletal proteins)
→
shows
→
Object:
immunohistochemistry_positivity
(Immunohistochemistry results)
Original: pan-cytokeratin AE1/AE3 and EMA#show#positivity in immunohistochemistry
#20910
high Confidence
Subject:
Acinar-cell_carcinoma
(Acinar cell carcinoma)
→
was_confirmed_by
→
Object:
ultrastructural_study
(Ultrastructural examination)
Original: Acinar-cell carcinoma#was confirmed by#histological and ultrastructural studies
#20909
high Confidence
Subject:
Acinar-cell_carcinoma
(Acinar cell carcinoma)
→
was_confirmed_by
→
Object:
histological_study
(Histological examination)
Original: Acinar-cell carcinoma#was confirmed by#histological and ultrastructural studies
#20908
high Confidence
Subject:
Basal_cell_layer
(Basal cell layer)
→
is_intact_in
→
Object:
benign_hyperplasias
(Benign hyperplasia)
Original: Basal cell layer (BCL)#is intact in#benign hyperplasias
#20904
high Confidence
Subject:
Alpha-actin
(α-Actin)
→
used_for
→
Object:
tumor characterization
(Tumor phenotype determination)
Original: Cytokeratin/ vimentin/ S-100/ melan-A/ vWF/ desmin/ actin/ and alpha-actin#were applied for#tumor characterization
#20903
high Confidence
Subject:
Actin
(Actin)
→
used_for
→
Object:
tumor characterization
(Tumor phenotype determination)
Original: Cytokeratin/ vimentin/ S-100/ melan-A/ vWF/ desmin/ actin/ and alpha-actin#were applied for#tumor characterization
#20902
high Confidence
Subject:
Desmin
(Desmin)
→
used_for
→
Object:
tumor characterization
(Tumor phenotype determination)
Original: Cytokeratin/ vimentin/ S-100/ melan-A/ vWF/ desmin/ actin/ and alpha-actin#were applied for#tumor characterization
#20901
high Confidence
Subject:
wxya
(Von Willebrand Factor)
→
used_for
→
Object:
tumor characterization
(Tumor phenotype determination)
Original: Cytokeratin/ vimentin/ S-100/ melan-A/ vWF/ desmin/ actin/ and alpha-actin#were applied for#tumor characterization
#20900
high Confidence
Subject:
Melan-A
(Melan-A protein)
→
used_for
→
Object:
tumor characterization
(Tumor phenotype determination)
Original: Cytokeratin/ vimentin/ S-100/ melan-A/ vWF/ desmin/ actin/ and alpha-actin#were applied for#tumor characterization
#20899
high Confidence
Subject:
S-100
(S-100 protein)
→
used_for
→
Object:
tumor characterization
(Tumor phenotype determination)
Original: Cytokeratin/ vimentin/ S-100/ melan-A/ vWF/ desmin/ actin/ and alpha-actin#were applied for#tumor characterization
#20898
high Confidence
Subject:
Vimentin
(Vimentin)
→
used_for
→
Object:
tumor characterization
(Tumor phenotype determination)
Original: Cytokeratin/ vimentin/ S-100/ melan-A/ vWF/ desmin/ actin/ and alpha-actin#were applied for#tumor characterization
#20897
high Confidence
Subject:
Cytokeratin
(Cytokeratin)
→
used_for
→
Object:
tumor characterization
(Tumor phenotype determination)
Original: Cytokeratin/ vimentin/ S-100/ melan-A/ vWF/ desmin/ actin/ and alpha-actin#were applied for#tumor characterization
#20891
high Confidence
Subject:
neoplasm
(Tumor cells)
→
exhibits
→
Object:
granular_eosinophilic_cytoplasm
(Cytoplasmic characteristics)
Original: Neoplasms#exhibit#solid or acinar growth pattern/ dense neoplastic cellularity/ uniform nuclei with prominent nucleoli/ and granular eosinophilic cytoplasm
#20890
high Confidence
Subject:
neoplasm
(Tumor cells)
→
exhibits
→
Object:
uniform_nuclei_with_prominent_nucleoli
(Nuclear characteristics)
Original: Neoplasms#exhibit#solid or acinar growth pattern/ dense neoplastic cellularity/ uniform nuclei with prominent nucleoli/ and granular eosinophilic cytoplasm
#20889
high Confidence
Subject:
neoplasm
(Tumor cells)
→
exhibits
→
Object:
dense_neoplastic_cellularity
(Cell density characteristics)
Original: Neoplasms#exhibit#solid or acinar growth pattern/ dense neoplastic cellularity/ uniform nuclei with prominent nucleoli/ and granular eosinophilic cytoplasm
#20888
high Confidence
Subject:
neoplasm
(Tumor cells)
→
exhibits
→
Object:
acinar_growth_pattern
(Histological characteristics)
Original: Neoplasms#exhibit#solid or acinar growth pattern/ dense neoplastic cellularity/ uniform nuclei with prominent nucleoli/ and granular eosinophilic cytoplasm
#20887
high Confidence
Subject:
neoplasm
(Tumor cells)
→
exhibits
→
Object:
solid_growth_pattern
(Histological characteristics)
Original: Neoplasms#exhibit#solid or acinar growth pattern/ dense neoplastic cellularity/ uniform nuclei with prominent nucleoli/ and granular eosinophilic cytoplasm
#20886
high Confidence
Subject:
papillary_appearance
(Morphological characteristics)
→
is_shown_by
→
Object:
CK7
(Structural proteins)
Original: Papillary appearance#is shown by#CK7
#20883
high Confidence
Subject:
nucleus_of_PTC_in_Graves_disease
(Cell structure)
→
shows
→
Object:
small_eccentric_nucleoli
(Nuclear characteristics)
Original: The nuclei of PTC in GD#show#prominent nuclear elongation/ pale powdery chromatin/ intranuclear grooves/ and small eccentric nucleoli
#20882
high Confidence
Subject:
nucleus_of_PTC_in_Graves_disease
(Cell structure)
→
shows
→
Object:
intranuclear_grooves
(Nuclear characteristics)
Original: The nuclei of PTC in GD#show#prominent nuclear elongation/ pale powdery chromatin/ intranuclear grooves/ and small eccentric nucleoli
#20881
high Confidence
Subject:
nucleus_of_PTC_in_Graves_disease
(Cell structure)
→
shows
→
Object:
pale_powdery_chromatin
(Chromatin characteristics)
Original: The nuclei of PTC in GD#show#prominent nuclear elongation/ pale powdery chromatin/ intranuclear grooves/ and small eccentric nucleoli
#20880
high Confidence
Subject:
nucleus_of_PTC_in_Graves_disease
(Cell structure)
→
shows
→
Object:
prominent_nuclear_elongation
(Nuclear characteristics)
Original: The nuclei of PTC in GD#show#prominent nuclear elongation/ pale powdery chromatin/ intranuclear grooves/ and small eccentric nucleoli
#20873
high Confidence
Subject:
Tumor
(Tumor)
→
diagnosed_as
→
Object:
ovarian_dysgerminoma
(Disease Type)
Original: Tumor#was diagnosed as#an ovarian dysgerminoma in a medaka
#20872
high Confidence
Subject:
cystic_sebaceous_adenoma
(Tumor)
→
is_marker_for
→
Object:
Muir-Torre_syndrome
(disease)
Original: Cystic sebaceous adenoma#has been reported as#a specific marker for Muir-Torre syndrome (MTS)
#20862
high Confidence
Subject:
Rhabdoid meningioma
(Tumor diseases)
→
differential_diagnosis_involves
→
Object:
atypical teratoid/rhabdoid tumor
(Tumor diseases)
Original: Rhabdoid meningioma#differential diagnosis involves#metastatic adenocarcinoma/ melanoma/ and atypical teratoid/rhabdoid tumor
#20861
high Confidence
Subject:
Rhabdoid meningioma
(Tumor diseases)
→
differential_diagnosis_involves
→
Object:
melanoma
(Tumor diseases)
Original: Rhabdoid meningioma#differential diagnosis involves#metastatic adenocarcinoma/ melanoma/ and atypical teratoid/rhabdoid tumor
#20860
high Confidence
Subject:
Rhabdoid meningioma
(Tumor diseases)
→
differential_diagnosis_involves
→
Object:
metastatic adenocarcinoma
(Tumor diseases)
Original: Rhabdoid meningioma#differential diagnosis involves#metastatic adenocarcinoma/ melanoma/ and atypical teratoid/rhabdoid tumor
#20857
high Confidence
Subject:
Extrarenal rhabdoid tumor
(Tumor diseases)
→
is_diagnosed_based_on
→
Object:
cytoplasmic intermediate filaments in epithelioid cells
(Cell morphological characteristics)
Original: Extrarenal rhabdoid tumor#is diagnosed based on#proliferation of epithelioid cells with large nuclei/ prominent nucleoli/ and cytoplasmic intermediate filaments
#20856
high Confidence
Subject:
Extrarenal rhabdoid tumor
(Tumor diseases)
→
is_diagnosed_based_on
→
Object:
prominent nucleoli in epithelioid cells
(Cell morphological characteristics)
Original: Extrarenal rhabdoid tumor#is diagnosed based on#proliferation of epithelioid cells with large nuclei/ prominent nucleoli/ and cytoplasmic intermediate filaments
#20855
high Confidence
Subject:
Extrarenal rhabdoid tumor
(Tumor diseases)
→
is_diagnosed_based_on
→
Object:
proliferation of epithelioid cells with large nuclei
(Cell morphological characteristics)
Original: Extrarenal rhabdoid tumor#is diagnosed based on#proliferation of epithelioid cells with large nuclei/ prominent nucleoli/ and cytoplasmic intermediate filaments
#20854
high Confidence
Subject:
Surveillance
(Medical monitoring behavior)
→
should_be_started_from
→
Object:
early_age
(Timing of diagnosis)
Original: Surveillance of renal tumor in FH gene germline mutation-positive patients#should be started from#early age using ultrasound sonography or magnetic resonance imaging
#20845
high Confidence
Subject:
computed_tomography
(Imaging methods)
→
revealed
→
Object:
pulmonary_mass
(Tumor type)
Original: Computed tomography#revealed#a pulmonary mass with vacuolar tumor cells and abundant eosinophilic cytoplasm
#20844
high Confidence
Subject:
immunohistochemical_staining
(Molecular detection methods)
→
detects
→
Object:
FH_deficiency
(Protein deficiency)
Original: Immunohistochemical staining#was performed on#300 uSMTs to detect FH deficiency
#20843
high Confidence
Subject:
immunohistochemical_staining
(Molecular detection methods)
→
was_performed_on
→
Object:
uSMTs
(Tumor type)
Original: Immunohistochemical staining#was performed on#300 uSMTs to detect FH deficiency
#20840
high Confidence
Subject:
Rhabdoid_cells
(Tumor cell type)
→
are_confirmed_by
→
Object:
electron_microscopic_studies
(Detection Technology)
Original: Rhabdoid cells#are confirmed by#immunohistochemical and electron microscopic studies
#20839
high Confidence
Subject:
Rhabdoid_cells
(Tumor cell type)
→
are_confirmed_by
→
Object:
immunohistochemical_studies
(Detection Technology)
Original: Rhabdoid cells#are confirmed by#immunohistochemical and electron microscopic studies
#20832
high Confidence
Subject:
Immunohistochemistry
(Diagnostic techniques)
→
shows
→
Object:
vimentin_positive_cytoplasmic_staining
(Protein expression)
Original: Immunohistochemistry#showed#positive cytoplasmic staining for cytokeratin and vimentin
#20831
high Confidence
Subject:
Immunohistochemistry
(Diagnostic techniques)
→
shows
→
Object:
cytokeratin_positive_cytoplasmic_staining
(Protein expression)
Original: Immunohistochemistry#showed#positive cytoplasmic staining for cytokeratin and vimentin
#20815
high Confidence
Subject:
fine_needle_aspiration_biopsy
(Pathological diagnosis technology)
→
diagnoses
→
Object:
proliferative_myositis
(disease)
Original: Proliferative myositis (PM)#is diagnosed by#fine needle aspiration biopsy (FNAB)
#20814
high Confidence
Subject:
expert_pathologists
(Clinical Experts)
→
support
→
Object:
benign_endometrial_polyp_diagnosis
(Clinical diagnosis)
Original: Expert pathologists#support#benign endometrial polyp diagnosis
#20812
high Confidence
Subject:
BBC
(Cytological testing methods)
→
is_sensitive_for
→
Object:
detecting_cholangiocarcinoma
(Diagnostic Process)
Original: BBC#is sensitive for#detecting cholangiocarcinoma in PSC patients
#20809
high Confidence
Subject:
morphologic_features_of_neoplastic_cells
(Cell morphology)
→
are_consistent_with
→
Object:
astrocytic_neoplasm
(Tumor)
Original: Morphologic features of neoplastic cells#were consistent with#astrocytic neoplasm
#20806
high Confidence
Subject:
BRG1
(Chromatin remodeling proteins)
→
expression_is_absent_in
→
Object:
unusual_RCC
(Disease classification)
Original: INI1 and BRG1 expression#are absent in#unusual RCC
#20805
high Confidence
Subject:
INI1
(Chromatin remodeling proteins)
→
expression_is_absent_in
→
Object:
unusual_RCC
(Disease classification)
Original: INI1 and BRG1 expression#are absent in#unusual RCC
#20784
high Confidence
Subject:
enlarged_nucleoli
(Nuclear components)
→
were
→
Object:
reliable_indicators_of_endometrial_cancer
(Diagnostic value)
Original: Enlarged nuclei and nucleoli in endometrial cells#were#reliable indicators of endometrial cancer
#20783
high Confidence
Subject:
enlarged_nuclei
(Nuclear components)
→
were
→
Object:
reliable_indicators_of_endometrial_cancer
(Diagnostic value)
Original: Enlarged nuclei and nucleoli in endometrial cells#were#reliable indicators of endometrial cancer
#20754
high Confidence
Subject:
epidermal_invasion
(Histological characteristics)
→
indicates
→
Object:
malignant_melanoma
(Malignant tumors)
Original: malignant melanoma#is diagnosed by#melanocytic cells with atypical nuclei/ prominent nucleoli/ mitoses/ and epidermal invasion
#20753
high Confidence
Subject:
Mitoses
(Cellular Processes)
→
indicates
→
Object:
malignant_melanoma
(Malignant tumors)
Original: malignant melanoma#is diagnosed by#melanocytic cells with atypical nuclei/ prominent nucleoli/ mitoses/ and epidermal invasion
#20752
high Confidence
Subject:
prominent_nucleoli
(Cell morphology)
→
indicates
→
Object:
malignant_melanoma
(Malignant tumors)
Original: malignant melanoma#is diagnosed by#melanocytic cells with atypical nuclei/ prominent nucleoli/ mitoses/ and epidermal invasion
#20751
high Confidence
Subject:
atypical_nuclei
(Cell morphology)
→
indicates
→
Object:
malignant_melanoma
(Malignant tumors)
Original: malignant melanoma#is diagnosed by#melanocytic cells with atypical nuclei/ prominent nucleoli/ mitoses/ and epidermal invasion
#20750
high Confidence
Subject:
melanocytic_cells
(Cell Type)
→
diagnoses
→
Object:
malignant_melanoma
(Malignant tumors)
Original: malignant melanoma#is diagnosed by#melanocytic cells with atypical nuclei/ prominent nucleoli/ mitoses/ and epidermal invasion
#20747
high Confidence
Subject:
adenoma_of_the_eccrine_glands
(Benign tumors)
→
is_diagnosed_based_on
→
Object:
histological_and_immunohistochemical_findings
(Diagnosis)
Original: adenoma of the eccrine glands#was diagnosed#based on histological and immunohistochemical findings
#20743
high Confidence
Subject:
BCL2
(Anti-apoptotic proteins)
→
correlates_with
→
Object:
clinicopathological_findings
(Clinicopathological characteristics)
Original: Ki-67 and bcl-2 expression#correlates with#clinicopathological findings
#20742
high Confidence
Subject:
KI67
(Cell proliferation markers)
→
correlates_with
→
Object:
clinicopathological_findings
(Clinicopathological characteristics)
Original: Ki-67 and bcl-2 expression#correlates with#clinicopathological findings
#20740
high Confidence
Subject:
spindle_cells
(Spindle cells)
→
are_observed_in
→
Object:
pulmonary_blastoma
(Tumor type)
Original: pulmonary blastoma#should be considered when#small spindle-shaped cells are observed
#20739
high Confidence
Subject:
FNAC
(Cytological detection technology)
→
allows
→
Object:
medical_carcinoma_to_be_considered_in_diagnosis
(Possibility of diagnosis)
Original: FNAC#allows#medullary carcinoma to be considered in diagnosis
#20737
high Confidence
Subject:
NUT_midline_carcinoma
(Tumor)
→
confirmed_by
→
Object:
fluorescence_in_situ_hybridization
(Molecular diagnostic technology)
Original: NUT midline carcinoma#confirmed by#cytogenetic and fluorescence in situ hybridization studies
#20736
high Confidence
Subject:
NUT_midline_carcinoma
(Tumor)
→
confirmed_by
→
Object:
cytogenetic_study
(Molecular diagnostic technology)
Original: NUT midline carcinoma#confirmed by#cytogenetic and fluorescence in situ hybridization studies
#20735
high Confidence
Subject:
application_of_immunohistochemistry_markers
(Immunohistochemistry)
→
contributes_to
→
Object:
correct_diagnosis
(Diagnostic outcome)
Original: Correct diagnosis#can be achieved with#a combination of awareness of the lesion/ familiarity with characteristic cytologic features/ and application of appropriate immunohistochemistry markers
#20734
high Confidence
Subject:
endometrial_cells
(Glandular epithelial cells)
→
diagnoses
→
Object:
adenocarcinoma
(Disease phenotype)
Original: cytology and immunohistochemistry findings#revealed#8 cases suspicious of adenocarcinoma in situ (AIS)/adenocarcinoma in cervical liquid-based cytology
#20733
high Confidence
Subject:
large_lymphoid_cells
(Lymphocytes)
→
express
→
Object:
LCA
(Protein markers)
Original: gingival biopsy#showed#massive infiltration by large lymphoid cells expressing CD79a/ CD138/ cytoplasmic lambda light chain/ and LCA
#20732
high Confidence
Subject:
large_lymphoid_cells
(Lymphocytes)
→
express
→
Object:
cytoplasmic_lambda_light_chain
(Protein markers)
Original: gingival biopsy#showed#massive infiltration by large lymphoid cells expressing CD79a/ CD138/ cytoplasmic lambda light chain/ and LCA
#20731
high Confidence
Subject:
large_lymphoid_cells
(Lymphocytes)
→
express
→
Object:
CD138
(Protein markers)
Original: gingival biopsy#showed#massive infiltration by large lymphoid cells expressing CD79a/ CD138/ cytoplasmic lambda light chain/ and LCA
#20730
high Confidence
Subject:
large_lymphoid_cells
(Lymphocytes)
→
express
→
Object:
CD79a
(Protein markers)
Original: gingival biopsy#showed#massive infiltration by large lymphoid cells expressing CD79a/ CD138/ cytoplasmic lambda light chain/ and LCA
#20725
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_negative_for
→
Object:
HMB-45
(Melanin-related antibodies)
Original: neoplastic cells#were negative for#smooth muscle actin/ muscle-specific actin/ myoglobin/ myogenin/ CD117/ cytokeratins/ carcinoembryonic antigen/ epithelial membrane antigen/ chromogranin/ CD34/ CD31/ S100 protein/ HMB-45
#20724
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_negative_for
→
Object:
S100_protein
(Cytoskeletal proteins)
Original: neoplastic cells#were negative for#smooth muscle actin/ muscle-specific actin/ myoglobin/ myogenin/ CD117/ cytokeratins/ carcinoembryonic antigen/ epithelial membrane antigen/ chromogranin/ CD34/ CD31/ S100 protein/ HMB-45
#20723
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_negative_for
→
Object:
CD31
(Cell surface molecules)
Original: neoplastic cells#were negative for#smooth muscle actin/ muscle-specific actin/ myoglobin/ myogenin/ CD117/ cytokeratins/ carcinoembryonic antigen/ epithelial membrane antigen/ chromogranin/ CD34/ CD31/ S100 protein/ HMB-45
#20722
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_negative_for
→
Object:
CD34
(Cell surface molecules)
Original: neoplastic cells#were negative for#smooth muscle actin/ muscle-specific actin/ myoglobin/ myogenin/ CD117/ cytokeratins/ carcinoembryonic antigen/ epithelial membrane antigen/ chromogranin/ CD34/ CD31/ S100 protein/ HMB-45
#20721
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_negative_for
→
Object:
Chromogranin
(Secretory granule protein)
Original: neoplastic cells#were negative for#smooth muscle actin/ muscle-specific actin/ myoglobin/ myogenin/ CD117/ cytokeratins/ carcinoembryonic antigen/ epithelial membrane antigen/ chromogranin/ CD34/ CD31/ S100 protein/ HMB-45
#20720
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_negative_for
→
Object:
epithelial_membrane_antigen
(Membrane Protein)
Original: neoplastic cells#were negative for#smooth muscle actin/ muscle-specific actin/ myoglobin/ myogenin/ CD117/ cytokeratins/ carcinoembryonic antigen/ epithelial membrane antigen/ chromogranin/ CD34/ CD31/ S100 protein/ HMB-45
#20719
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_negative_for
→
Object:
carcinoembryonic_antigen
(Tumor markers)
Original: neoplastic cells#were negative for#smooth muscle actin/ muscle-specific actin/ myoglobin/ myogenin/ CD117/ cytokeratins/ carcinoembryonic antigen/ epithelial membrane antigen/ chromogranin/ CD34/ CD31/ S100 protein/ HMB-45
#20718
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_negative_for
→
Object:
cytokeratins
(Cytoskeletal proteins)
Original: neoplastic cells#were negative for#smooth muscle actin/ muscle-specific actin/ myoglobin/ myogenin/ CD117/ cytokeratins/ carcinoembryonic antigen/ epithelial membrane antigen/ chromogranin/ CD34/ CD31/ S100 protein/ HMB-45
#20717
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_negative_for
→
Object:
CD117
(Receptor protein)
Original: neoplastic cells#were negative for#smooth muscle actin/ muscle-specific actin/ myoglobin/ myogenin/ CD117/ cytokeratins/ carcinoembryonic antigen/ epithelial membrane antigen/ chromogranin/ CD34/ CD31/ S100 protein/ HMB-45
#20716
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_negative_for
→
Object:
myogenin
(Transcription Factors)
Original: neoplastic cells#were negative for#smooth muscle actin/ muscle-specific actin/ myoglobin/ myogenin/ CD117/ cytokeratins/ carcinoembryonic antigen/ epithelial membrane antigen/ chromogranin/ CD34/ CD31/ S100 protein/ HMB-45
#20715
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_negative_for
→
Object:
myoglobin
(Cytoskeletal proteins)
Original: neoplastic cells#were negative for#smooth muscle actin/ muscle-specific actin/ myoglobin/ myogenin/ CD117/ cytokeratins/ carcinoembryonic antigen/ epithelial membrane antigen/ chromogranin/ CD34/ CD31/ S100 protein/ HMB-45
#20714
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_negative_for
→
Object:
muscle-specific_actin
(Cytoskeletal proteins)
Original: neoplastic cells#were negative for#smooth muscle actin/ muscle-specific actin/ myoglobin/ myogenin/ CD117/ cytokeratins/ carcinoembryonic antigen/ epithelial membrane antigen/ chromogranin/ CD34/ CD31/ S100 protein/ HMB-45
#20713
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_negative_for
→
Object:
smooth_muscle_actin
(Cytoskeletal proteins)
Original: neoplastic cells#were negative for#smooth muscle actin/ muscle-specific actin/ myoglobin/ myogenin/ CD117/ cytokeratins/ carcinoembryonic antigen/ epithelial membrane antigen/ chromogranin/ CD34/ CD31/ S100 protein/ HMB-45
#20710
high Confidence
Subject:
tumor
(Tumor)
→
diagnosed_as
→
Object:
AcCC_of_the_breast
(Tumor type)
Original: Tumor#diagnosed as#AcCC of the breast
#20700
high Confidence
Subject:
malignant_fibrous_histiocytoma
(Tumor)
→
is_diagnosed_by
→
Object:
electron_microscopy
(Diagnostic Methods)
Original: Malignant fibrous histiocytoma#is diagnosed by#cytological analysis/ histopathologic analysis/ immunohistochemical staining/ and electron microscopy
#20699
high Confidence
Subject:
malignant_fibrous_histiocytoma
(Tumor)
→
is_diagnosed_by
→
Object:
immunohistochemical_staining
(Diagnostic Methods)
Original: Malignant fibrous histiocytoma#is diagnosed by#cytological analysis/ histopathologic analysis/ immunohistochemical staining/ and electron microscopy
#20698
high Confidence
Subject:
malignant_fibrous_histiocytoma
(Tumor)
→
is_diagnosed_by
→
Object:
histopathologic_analysis
(Diagnostic Methods)
Original: Malignant fibrous histiocytoma#is diagnosed by#cytological analysis/ histopathologic analysis/ immunohistochemical staining/ and electron microscopy
#20697
high Confidence
Subject:
malignant_fibrous_histiocytoma
(Tumor)
→
is_diagnosed_by
→
Object:
cytological_analysis
(Diagnostic Methods)
Original: Malignant fibrous histiocytoma#is diagnosed by#cytological analysis/ histopathologic analysis/ immunohistochemical staining/ and electron microscopy
#20695
high Confidence
Subject:
Fine-needle_aspiration_cytologic_diagnosis
(Diagnostic techniques)
→
is_supported_by
→
Object:
fine_structural_correlation
(Ultrastructural evidence)
Original: Fine-needle aspiration cytologic diagnosis#is supported by#clinicopathologic and fine structural correlations
#20694
high Confidence
Subject:
Fine-needle_aspiration_cytologic_diagnosis
(Diagnostic techniques)
→
is_supported_by
→
Object:
clinicopathologic_correlation
(Clinical pathological evidence)
Original: Fine-needle aspiration cytologic diagnosis#is supported by#clinicopathologic and fine structural correlations
#20691
high Confidence
Subject:
34_year_old_man
(Patient characteristics)
→
diagnosed_with
→
Object:
clear_cell_carcinoma
(Tumor type)
Original: 34-year-old man#was diagnosed with#clear-cell carcinoma
#20690
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
expresses
→
Object:
brachyury
(Transcription Factors)
Original: tumor cells#expressed#cytokeratin/ epithelial membrane antigen/ brachyury
#20689
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
expresses
→
Object:
epithelial_membrane_antigen
(Cell membrane antigen)
Original: tumor cells#expressed#cytokeratin/ epithelial membrane antigen/ brachyury
#20688
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
expresses
→
Object:
cytokeratin
(Cytoskeletal proteins)
Original: tumor cells#expressed#cytokeratin/ epithelial membrane antigen/ brachyury
#20687
high Confidence
Subject:
INI1
(Tumor suppressor proteins)
→
shows_loss_in
→
Object:
pediatric_poorly_differentiated_chordoma
(Tumor type)
Original: pediatric poorly differentiated chordoma cases#showed#INI1 loss
#20677
high Confidence
Subject:
cytotoxic_granules
(Cytotoxic granules)
→
are_present_in
→
Object:
neoplastic_cells
(Tumor cells)
Original: Neoplastic cells#exhibit#cytoplasmic CD3+/ CD56+/ and cytotoxic granules
#20676
high Confidence
Subject:
CD56
(NK cell marker protein)
→
is_upregulated_in
→
Object:
neoplastic_cells
(Tumor cells)
Original: Neoplastic cells#exhibit#cytoplasmic CD3+/ CD56+/ and cytotoxic granules
#20675
high Confidence
Subject:
CD3
(T cell marker protein)
→
is_upregulated_in
→
Object:
neoplastic_cells
(Tumor cells)
Original: Neoplastic cells#exhibit#cytoplasmic CD3+/ CD56+/ and cytotoxic granules
#20674
high Confidence
Subject:
Malignant_rhabdoid_tumor
(Tumor diseases)
→
is_defined_by
→
Object:
histologic_phenotype
(Pathological phenotype)
Original: Malignant rhabdoid tumor#is defined by#its histologic phenotype
#20673
high Confidence
Subject:
Oncocytoma-like_AML
(Tumor diseases)
→
is
→
Object:
rare_renal_neoplasm
(Tumor diseases)
Original: Oncocytoma-like AML#is#a rare renal neoplasm
#20670
high Confidence
Subject:
Malignant_rhabdoid_tumor
(Tumor type)
→
possesses
→
Object:
prominent_nucleoli
(Cell morphology)
Original: Malignant rhabdoid tumor#possesses#cells with prominent nucleoli
#20664
high Confidence
Subject:
Morphological_features
(Histological characteristics)
→
support
→
Object:
diagnosis_of_pilomatrix_carcinoma
(Disease diagnosis)
Original: Morphological features#favor#a diagnosis of pilomatrix carcinoma
#20663
high Confidence
Subject:
T_cells
(T cells)
→
are_typical_of
→
Object:
anaplastic_large_T-cell_lymphoma
(Lymphoma)
Original: Features#are considered typical of#anaplastic large T-cell lymphoma
#20662
high Confidence
Subject:
Autopsy
(Autopsy)
→
disclosed
→
Object:
Postirradiation_sarcoma
(Tumor phenotype)
Original: Autopsy#disclosed#a postirradiation sarcoma in the pituitary area
#20660
high Confidence
Subject:
16-year-old_female_patient
(Patient characteristics)
→
was_diagnosed_with
→
Object:
aggressive_Crooke_cell_macroadenoma
(Tumor phenotype)
Original: A 16-year-old female patient#was diagnosed with#an aggressive Crooke cell macroadenoma
#20656
high Confidence
Subject:
immunohistochemical_staining
(Immunohistochemistry)
→
showed
→
Object:
CD56
(Protein markers)
Original: Immunohistochemical staining#showed#diffuse expression of CK/ EMA/ Syn/ and CD56
#20655
high Confidence
Subject:
immunohistochemical_staining
(Immunohistochemistry)
→
showed
→
Object:
Syn
(Protein markers)
Original: Immunohistochemical staining#showed#diffuse expression of CK/ EMA/ Syn/ and CD56
#20654
high Confidence
Subject:
immunohistochemical_staining
(Immunohistochemistry)
→
showed
→
Object:
EMA
(Protein markers)
Original: Immunohistochemical staining#showed#diffuse expression of CK/ EMA/ Syn/ and CD56
#20653
high Confidence
Subject:
immunohistochemical_staining
(Immunohistochemistry)
→
showed
→
Object:
CK
(Protein markers)
Original: Immunohistochemical staining#showed#diffuse expression of CK/ EMA/ Syn/ and CD56
#20652
high Confidence
Subject:
patients
(patient)
→
diagnosed_with
→
Object:
maxillofacial_neuroendocrine_carcinoma
(Tumor)
Original: 11 patients#were diagnosed with#maxillofacial neuroendocrine carcinoma
#20651
high Confidence
Subject:
LBC_preparation
(Liquid-based cytology)
→
showed
→
Object:
tumor_cells
(Tumor cells)
Original: LBC preparation#showed#isolated tumor cells with small nucleoli
#20650
high Confidence
Subject:
Electron_microscopy
(Electron microscopy)
→
established
→
Object:
epithelioid_hemangioendothelioma
(Tumor)
Original: Electron microscopy#established#a diagnosis of epithelioid hemangioendothelioma (EHE)
#20649
high Confidence
Subject:
Cytopathologic_examination
(Pathological examination)
→
revealed
→
Object:
plasmacytoid_malignant_cells
(Tumor cells)
Original: Cytopathologic examination#revealed#large undifferentiated plasmacytoid malignant cells with prominent nucleoli
#20647
high Confidence
Subject:
Immunohistochemical stain
(Detection Methods)
→
includes
→
Object:
HER2
(Receptor protein)
Original: Immunohistochemical stains#include#estrogen receptor/ progesterone receptor/ HER2/ AR/ endothelial growth factor receptor/ and keratin 5/6
#20646
high Confidence
Subject:
Immunohistochemical stain
(Detection Methods)
→
includes
→
Object:
progesterone receptor
(Receptor protein)
Original: Immunohistochemical stains#include#estrogen receptor/ progesterone receptor/ HER2/ AR/ endothelial growth factor receptor/ and keratin 5/6
#20645
high Confidence
Subject:
Immunohistochemical stain
(Detection Methods)
→
includes
→
Object:
estrogen receptor
(Receptor protein)
Original: Immunohistochemical stains#include#estrogen receptor/ progesterone receptor/ HER2/ AR/ endothelial growth factor receptor/ and keratin 5/6
#20638
high Confidence
Subject:
Hodgkin's_disease
(disease)
→
is_classified_into
→
Object:
mixed_cellularity_type
(Disease classification)
Original: Hodgkin's disease#is classified into#lymphocyte predominant/ nodular sclerosing/ and mixed cellularity types
#20637
high Confidence
Subject:
Hodgkin's_disease
(disease)
→
is_classified_into
→
Object:
nodular_sclerosing_type
(Disease classification)
Original: Hodgkin's disease#is classified into#lymphocyte predominant/ nodular sclerosing/ and mixed cellularity types
#20636
high Confidence
Subject:
Hodgkin's_disease
(disease)
→
is_classified_into
→
Object:
lymphocyte_predominant_type
(Disease classification)
Original: Hodgkin's disease#is classified into#lymphocyte predominant/ nodular sclerosing/ and mixed cellularity types
#20635
high Confidence
Subject:
Askin_tumor
(Tumor)
→
is_diagnosed_by
→
Object:
fine_needle_aspiration_cytology
(Diagnostic Methods)
Original: Askin tumor#is diagnosed by#fine needle aspiration cytology
#20634
high Confidence
Subject:
histologic_diagnosis
(Histological diagnosis)
→
identifies
→
Object:
poroid_hidradenoma
(disease)
Original: Histologic diagnosis#is#poroid hidradenoma
#20623
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
did_not_express
→
Object:
p63
(Transcription Factors)
Original: Tumor cells#did not express#p63
#20622
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
expressed
→
Object:
GCDFP15
(protein)
Original: Tumor cells#expressed#adipophilin/ PRAME (cytoplasmic pattern)/ androgen receptor/ BerEP4/ and GCDFP15
#20621
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
expressed
→
Object:
BerEP4
(protein)
Original: Tumor cells#expressed#adipophilin/ PRAME (cytoplasmic pattern)/ androgen receptor/ BerEP4/ and GCDFP15
#20620
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
expressed
→
Object:
androgen_receptor
(Receptor protein)
Original: Tumor cells#expressed#adipophilin/ PRAME (cytoplasmic pattern)/ androgen receptor/ BerEP4/ and GCDFP15
#20619
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
expressed
→
Object:
PRAME
(protein)
Original: Tumor cells#expressed#adipophilin/ PRAME (cytoplasmic pattern)/ androgen receptor/ BerEP4/ and GCDFP15
#20618
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
expressed
→
Object:
adipophilin
(protein)
Original: Tumor cells#expressed#adipophilin/ PRAME (cytoplasmic pattern)/ androgen receptor/ BerEP4/ and GCDFP15
#20616
high Confidence
Subject:
biopsy_specimen
(Histological samples)
→
contained
→
Object:
adenocarcinoma
(Tumor type)
Original: Biopsy specimens#contained#invasive neoplasm composed of neuroendocrine carcinoma and adenocarcinoma
#20615
high Confidence
Subject:
biopsy_specimen
(Histological samples)
→
contained
→
Object:
neuroendocrine_carcinoma
(Tumor type)
Original: Biopsy specimens#contained#invasive neoplasm composed of neuroendocrine carcinoma and adenocarcinoma
#20614
high Confidence
Subject:
endoscopic_submucosal_dissection
(Endoscopic surgery)
→
revealed
→
Object:
tubular_adenocarcinoma
(Tumor type)
Original: endoscopic submucosal dissection#revealed#tubular adenocarcinoma/ well-differentiated/ with slight submucosal invasion
#20613
high Confidence
Subject:
EWSR1-ATF1
(Gene fusion)
→
is_confirmed_in
→
Object:
malignant_gastrointestinal_neuroectodermal_tumor_case2
(Tumor diseases)
Original: next generation sequencing#confirmed#EWSR1-ATF1 gene fusion in case 2
#20609
high Confidence
Subject:
STK11_gene_alterations
(Gene mutation)
→
are_identified_in
→
Object:
STK11_adnexal_tumor
(Tumor type)
Original: STK11 gene alterations#are identified in#most cases of STK11 adnexal tumor
#20597
high Confidence
Subject:
metanephric_adenoma
(Tumor type)
→
is
→
Object:
benign_renal_neoplasm
(Tumor type)
Original: Metanephric adenoma (MA)#is#a rare benign renal neoplasm
#20594
high Confidence
Subject:
fine_needle_aspiration_cytology
(Cytological techniques)
→
is_used_for
→
Object:
diagnosis_of_malignant_rhabdoid_tumor_of_liver
(Disease diagnosis)
Original: malignant rhabdoid tumor of the liver#is diagnosed by#fine needle aspiration cytology
#20576
high Confidence
Subject:
PTPRB
(Tumor suppressor genes)
→
mutation_is_detected_by
→
Object:
next-generation_sequencing
(Molecular detection technology)
Original: Next-generation sequencing#demonstrated#a novel IGLV2-14/IGLL5 fusion and mutations or deletions in tumor suppressor genes such as PTPRB/ PPP2CB/ and UPK1A
#20567
high Confidence
Subject:
AT8_epitope_of_Tau
(Protein modified epitope)
→
is_marker_of
→
Object:
neuronal_cell_differentiation
(Cell differentiation process)
Original: AT8 epitope of Tau#is a marker of#neuronal cell differentiation
#20563
high Confidence
Subject:
Nucleolus
(Cellular substructure)
→
is_found_in
→
Object:
human_cancers
(Disease phenotype)
Original: Nucleolus#is found in#a broad range of human cancers
#20488
high Confidence
Subject:
TP53
(Tumor suppressor genes)
→
is_overexpressed_in
→
Object:
HCC_tumors
(Tumor tissue)
Original: p53 overexpression#was observed in#22.5% of tumors
#20377
high Confidence
Subject:
HMNA
(Nucleoprotein)
→
is_a_marker_for
→
Object:
leukemic_cells
(Tumor cells)
Original: HMNA#is a marker for#leukemic cells
#20341
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
PAX8
(Transcription Factors)
Original: tumors#are variably positive for#EMA/ CK7/ CA9/ PAX8
#20340
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CA9
(Carbonic anhydrase)
Original: tumors#are variably positive for#EMA/ CK7/ CA9/ PAX8
#20339
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CK7
(Cytokeratin)
Original: tumors#are variably positive for#EMA/ CK7/ CA9/ PAX8
#20338
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
EMA
(Epithelial membrane antigen)
Original: tumors#are variably positive for#EMA/ CK7/ CA9/ PAX8
#20337
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
Mitochondria
(Mitochondria)
Original: tumors#are diffusely positive for#vimentin/ CD10/ RCC/ CAM5.2/ P504s/ mitochondria
#20336
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
P504s
(Enzymes)
Original: tumors#are diffusely positive for#vimentin/ CD10/ RCC/ CAM5.2/ P504s/ mitochondria
#20335
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CAM5.2
(Cytokeratin)
Original: tumors#are diffusely positive for#vimentin/ CD10/ RCC/ CAM5.2/ P504s/ mitochondria
#20334
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
RCC
(Renal cell carcinoma associated antigen)
Original: tumors#are diffusely positive for#vimentin/ CD10/ RCC/ CAM5.2/ P504s/ mitochondria
#20333
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD10
(Cell surface proteins)
Original: tumors#are diffusely positive for#vimentin/ CD10/ RCC/ CAM5.2/ P504s/ mitochondria
#20332
high Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
vimentin
(Intermediate filament protein)
Original: tumors#are diffusely positive for#vimentin/ CD10/ RCC/ CAM5.2/ P504s/ mitochondria
#20315
high Confidence
Subject:
AgNORs
(Nucleolar Organizing Region Marker)
→
is_used_to_assess
→
Object:
tumor_proliferation
(Tumor proliferation)
Original: PCNA and AgNOR#are used to assess#salivary gland tumor proliferation
#20314
high Confidence
Subject:
PCNA
(Proliferation-related proteins)
→
is_used_to_assess
→
Object:
tumor_proliferation
(Tumor proliferation)
Original: PCNA and AgNOR#are used to assess#salivary gland tumor proliferation
#20311
high Confidence
Subject:
SNORA23_expression
(Noncoding RNA)
→
is_lower_in
→
Object:
non-tumor_tissue
(Normal tissue)
Original: SNORA23 expression#is increased in#human PDAC tissues compared with non-tumor tissues
#20310
high Confidence
Subject:
SNORA23_expression
(Noncoding RNA)
→
is_increased_in
→
Object:
human_PDAC_tissue
(Disease Organization)
Original: SNORA23 expression#is increased in#human PDAC tissues compared with non-tumor tissues
#20309
high Confidence
Subject:
SNORA23
(Noncoding RNA)
→
was_not_detected_in
→
Object:
non-tumor_pancreatic_tissue
(Normal tissue)
Original: SNORA23#was detected in#human PDAC specimens but not in non-tumor pancreatic tissue
#20308
high Confidence
Subject:
SNORA23
(Noncoding RNA)
→
was_detected_in
→
Object:
human_PDAC_specimen
(Disease Organization)
Original: SNORA23#was detected in#human PDAC specimens but not in non-tumor pancreatic tissue
#20305
high Confidence
Subject:
tumor_cell
(Tumor cells)
→
exhibits
→
Object:
nuclear_atypia
(Nuclear abnormalities)
Original: Tumor cells#exhibit#nuclear atypia/ indentations nuclei/ and prominent nucleoli
#20292
high Confidence
Subject:
AMACR
(Enzymes)
→
is_equivalent_to
→
Object:
p63_AMACR_cocktail
(Immunohistochemistry reagents)
Original: p63/AMACR cocktail#is equivalent to#each antibody separately for diagnosing prostatic carcinoma
#20291
high Confidence
Subject:
p63
(Transcription Factors)
→
is_equivalent_to
→
Object:
p63_AMACR_cocktail
(Immunohistochemistry reagents)
Original: p63/AMACR cocktail#is equivalent to#each antibody separately for diagnosing prostatic carcinoma
#20290
high Confidence
Subject:
p63
(Transcription Factors)
→
is_equivalent_to
→
Object:
AMACR
(Enzymes)
Original: p63/AMACR cocktail#is equivalent to#each antibody separately for diagnosing prostatic carcinoma
#20289
high Confidence
Subject:
AgNORs
(Nucleolar Organizing Region Marker)
→
differentiations
→
Object:
ameloblastoma
(Tumor type)
Original: Argyrophilic nucleolar organizing regions (AgNORs)#differentiate#ameloblastic carcinoma from ameloblastoma
#20288
high Confidence
Subject:
AgNORs
(Nucleolar Organizing Region Marker)
→
differentiations
→
Object:
ameloblastic_carcinoma
(Tumor type)
Original: Argyrophilic nucleolar organizing regions (AgNORs)#differentiate#ameloblastic carcinoma from ameloblastoma
#20287
high Confidence
Subject:
cytopathologic_cellular_features
(Cell morphology)
→
correlated_with
→
Object:
high_grade_diagnosis
(High-grade diagnosis)
Original: Cytopathologic cellular features#correlated with#a high-grade diagnosis
#20277
high Confidence
Subject:
anaplastic_medulloblastoma
(Tumor type)
→
differentially_diagnosed_from
→
Object:
large_cell_lymphoma
(Tumor type)
Original: Differential diagnosis of anaplastic medulloblastoma#includes#metastatic carcinomas and large cell lymphoma
#20276
high Confidence
Subject:
anaplastic_medulloblastoma
(Tumor type)
→
differentially_diagnosed_from
→
Object:
metastatic_carcinoma
(Tumor type)
Original: Differential diagnosis of anaplastic medulloblastoma#includes#metastatic carcinomas and large cell lymphoma
#20275
high Confidence
Subject:
duodenal_tumors
(Tumor)
→
were_pointed_out_by
→
Object:
upper_gastrointestinal_endoscopy
(Diagnostic techniques)
Original: multiple duodenal tumors#were pointed out by#upper gastrointestinal endoscopy
#20272
high Confidence
Subject:
cytopathological_findings
(Pathological characteristics)
→
correlate_with
→
Object:
histopathological_findings
(Pathological characteristics)
Original: Cytopathological findings#correlate with#histopathological findings in uterine MMMT
#20265
high Confidence
Subject:
Laparoscopic_biopsy
(Tissue sampling techniques)
→
revealed
→
Object:
angiosarcoma_in_abdominal_mass
(Tumor)
Original: Laparoscopic biopsies#revealed#angiosarcoma in liver/abdominal masses
#20264
high Confidence
Subject:
Laparoscopic_biopsy
(Tissue sampling techniques)
→
revealed
→
Object:
angiosarcoma_in_liver
(Tumor)
Original: Laparoscopic biopsies#revealed#angiosarcoma in liver/abdominal masses
#20260
high Confidence
Subject:
diagnosis
(Diagnosis conclusion)
→
was
→
Object:
poorly_differentiated_eccrine_adenocarcinoma
(Tumor type)
Original: Diagnosis#was#a poorly differentiated eccrine adenocarcinoma
#20259
high Confidence
Subject:
biopsy
(Histological procedures)
→
was_done_to_make
→
Object:
definitive_diagnosis
(Diagnosis conclusion)
Original: Biopsy#was done to make#a definitive diagnosis
#20258
high Confidence
Subject:
HepPar1
(Liver-specific antigen)
→
shows_positivity_in
→
Object:
Immunohistochemical_stains
(Detection Methods)
Original: Immunohistochemical stains#showed#positivity for E-Cadherin/ Carcinoembryonic Antigen/ and HepPar1
#20257
high Confidence
Subject:
Carcinoembryonic_Antigen
(Tumor markers)
→
shows_positivity_in
→
Object:
Immunohistochemical_stains
(Detection Methods)
Original: Immunohistochemical stains#showed#positivity for E-Cadherin/ Carcinoembryonic Antigen/ and HepPar1
#20256
high Confidence
Subject:
E-Cadherin
(Cell adhesion molecules)
→
shows_positivity_in
→
Object:
Immunohistochemical_stains
(Detection Methods)
Original: Immunohistochemical stains#showed#positivity for E-Cadherin/ Carcinoembryonic Antigen/ and HepPar1
#20255
high Confidence
Subject:
Metastatic_breast_carcinoma_to_thyroid
(Tumor)
→
mimics
→
Object:
primary_thyroid_carcinoma_on_FNA
(Tumor)
Original: Metastatic breast carcinoma to the thyroid#mimics#primary thyroid carcinoma on FNA
#20246
high Confidence
Subject:
color_Doppler_ultrasonography
(Medical imaging technology)
→
confirms
→
Object:
tumor
(Tumor)
Original: All tumors#were clinically suspected and confirmed by#arteriography or color Doppler ultrasonography
#20245
high Confidence
Subject:
arteriography
(Medical imaging technology)
→
confirms
→
Object:
tumor
(Tumor)
Original: All tumors#were clinically suspected and confirmed by#arteriography or color Doppler ultrasonography
#20239
high Confidence
Subject:
FH_gene_abnormalities
(Genetic abnormalities)
→
showed
→
Object:
positive_staining_for_2SC
(Molecular markers)
Original: Tumors with FH gene abnormalities#showed#positive staining for 2SC
#20238
high Confidence
Subject:
Papillary-cystic_neoplasm
(Tumor type)
→
is_located_in
→
Object:
Pancreas
(organ)
Original: Papillary-cystic neoplasm#is located in#the pancreas
#20237
high Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_positive_for
→
Object:
AMACR
(Enzymes)
Original: Neoplastic cells#are positive for#AMACR
#20222
high Confidence
Subject:
carcinoid_tumors
(Tumor type)
→
are_limited_to
→
Object:
urinary_bladder
(organ)
Original: Carcinoid tumors#are limited to#urinary bladder
#20221
high Confidence
Subject:
diagnosis
(Diagnosis conclusion)
→
is
→
Object:
anaplastic_oligodendroglioma
(Tumor type)
Original: diagnosis#is#anaplastic oligodendroglioma
#20215
high Confidence
Subject:
Histological_assessment
(Histological evaluation)
→
diagnoses
→
Object:
Hurthle_cell_carcinoma
(Tumor type)
Original: Histological assessment#diagnosed#papillary carcinoma/ Hurthle cell carcinoma/ and multinodular goitre with degenerate changes
#20214
high Confidence
Subject:
Histological_assessment
(Histological evaluation)
→
diagnoses
→
Object:
papillary_carcinoma
(Tumor type)
Original: Histological assessment#diagnosed#papillary carcinoma/ Hurthle cell carcinoma/ and multinodular goitre with degenerate changes
#20211
high Confidence
Subject:
PSA
(Protein markers)
→
is_localized_in
→
Object:
prostatic_carcinoma
(Tumor diseases)
Original: We#investigated#localizations of PSA in prostatic carcinomas
#20192
high Confidence
Subject:
atypical_round_cells
(Tumor cell subtype)
→
are_positively_stained_for
→
Object:
Thyroglobulin
(protein)
Original: atypical round cells#are positively stained for#thyroglobulin
#20191
high Confidence
Subject:
mass
(Radiological entity)
→
is_diagnostic_of
→
Object:
poorly_differentiated_adenocarcinoma
(Tumor phenotype)
Original: Mass#diagnosed as#poorly differentiated adenocarcinoma
#20190
high Confidence
Subject:
Gleason_score
(Histopathological scoring)
→
ranges_to
→
Object:
5
(Numerical indicators)
Original: Gleason's score#ranges from#3 to 5
#20189
high Confidence
Subject:
Gleason_score
(Histopathological scoring)
→
ranges_from
→
Object:
3
(Numerical indicators)
Original: Gleason's score#ranges from#3 to 5
#20185
high Confidence
Subject:
epithelioid_angiomyolipoma
(Tumor)
→
is_recognized_as
→
Object:
recently_documented_tumor_entity
(Tumor type)
Original: Epithelioid angiomyolipoma#is recognized as#a recently documented tumor entity
#20182
high Confidence
Subject:
MART-1
(Molecular markers)
→
stains
→
Object:
tumor
(Tumor tissue)
Original: The tumor#stained with#HMB-45 and MART-1
#20181
high Confidence
Subject:
HMB-45
(Molecular markers)
→
stains
→
Object:
tumor
(Tumor tissue)
Original: The tumor#stained with#HMB-45 and MART-1
#20180
high Confidence
Subject:
gastric-type_ECA_component
(Tumor tissue composition)
→
tested_negative_for
→
Object:
high-risk_HPV
(Viral markers)
Original: The gastric-type ECA component#tested#negative for p16 and high-risk HPV
#20179
high Confidence
Subject:
gastric-type_ECA_component
(Tumor tissue composition)
→
tested_negative_for
→
Object:
p16
(Tumor markers)
Original: The gastric-type ECA component#tested#negative for p16 and high-risk HPV
#20176
high Confidence
Subject:
vimentin
(Intermediate filament protein)
→
is_positive_marker_in
→
Object:
malignant_melanoma
(disease)
Original: Immunopositivity for S100 protein/ HMB45/ and vimentin#distinguishes#malignant melanomas
#20175
high Confidence
Subject:
HMB45
(Monoclonal antibodies)
→
is_positive_marker_in
→
Object:
malignant_melanoma
(disease)
Original: Immunopositivity for S100 protein/ HMB45/ and vimentin#distinguishes#malignant melanomas
#20174
high Confidence
Subject:
S100_protein
(Calcium Binding Protein)
→
is_positive_marker_in
→
Object:
malignant_melanoma
(disease)
Original: Immunopositivity for S100 protein/ HMB45/ and vimentin#distinguishes#malignant melanomas
#20173
high Confidence
Subject:
Blastemal_cells
(Germ Cell)
→
recognized_in
→
Object:
Wilms_tumor
(Disease Type)
Original: Blastemal cells#were recognized in#all cases as small/ round cells with slightly oval nucleoli and fine/ evenly dispersed chromatin
#20172
high Confidence
Subject:
SPC cases
(Tumor Cases)
→
indicated
→
Object:
diffuse positivity for synaptophysin
(Protein expression characteristics)
Original: SPC cases#indicated#diffuse positivity for chromogranin A and/or synaptophysin
#20171
high Confidence
Subject:
SPC cases
(Tumor Cases)
→
indicated
→
Object:
diffuse positivity for chromogranin A
(Protein expression characteristics)
Original: SPC cases#indicated#diffuse positivity for chromogranin A and/or synaptophysin
#20142
high Confidence
Subject:
cytomorphologic_features
(Cell morphology)
→
help
→
Object:
distinguish_benign_and_malignant_endometrial_lesions
(Diagnostic value)
Original: Cytomorphologic features#help#distinguish benign and malignant endometrial lesions
#20140
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
S-100_protein
(Protein markers)
Original: Immunohistochemical staining#showed#tumor cells positive for Vimentin/ CD34/ Melan-A/ HMB45/ and S-100
#20139
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
HMB45
(Protein markers)
Original: Immunohistochemical staining#showed#tumor cells positive for Vimentin/ CD34/ Melan-A/ HMB45/ and S-100
#20138
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
Melan-A
(Protein markers)
Original: Immunohistochemical staining#showed#tumor cells positive for Vimentin/ CD34/ Melan-A/ HMB45/ and S-100
#20137
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD34
(Protein markers)
Original: Immunohistochemical staining#showed#tumor cells positive for Vimentin/ CD34/ Melan-A/ HMB45/ and S-100
#20136
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
Vimentin
(Protein markers)
Original: Immunohistochemical staining#showed#tumor cells positive for Vimentin/ CD34/ Melan-A/ HMB45/ and S-100
#20135
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD68
(Protein markers)
Original: Tumor cells#were positive for#S-100 protein and CD68
#20134
high Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
S-100_protein
(Protein markers)
Original: Tumor cells#were positive for#S-100 protein and CD68
#20133
high Confidence
Subject:
Ki-67_staining
(Molecular markers)
→
assists_in
→
Object:
diagnosis_of_hyalinizing_trabecular_tumor
(Disease diagnosis)
Original: Ki-67 staining#can assist in#diagnosis of HTT
#20131
high Confidence
Subject:
biopsy_findings
(Histological diagnosis)
→
diagnosed
→
Object:
histiocytic_sarcoma
(Disease phenotype)
Original: biopsy findings#diagnosed#histiocytic sarcoma
#20130
high Confidence
Subject:
alpha_smooth_muscle_actin
(protein)
→
shows
→
Object:
negative_reaction
(Test results)
Original: Epithelial membrane antigen (EMA)/ cytokeratin/ and alpha-smooth muscle action (alpha-SMA)#showed#negative reactions
#20129
high Confidence
Subject:
cytokeratin
(protein)
→
shows
→
Object:
negative_reaction
(Test results)
Original: Epithelial membrane antigen (EMA)/ cytokeratin/ and alpha-smooth muscle action (alpha-SMA)#showed#negative reactions
#20128
high Confidence
Subject:
epithelial_membrane_antigen
(protein)
→
shows
→
Object:
negative_reaction
(Test results)
Original: Epithelial membrane antigen (EMA)/ cytokeratin/ and alpha-smooth muscle action (alpha-SMA)#showed#negative reactions
#20127
high Confidence
Subject:
Lysosome
(Organelles)
→
shows
→
Object:
positive_reaction
(Test results)
Original: Alpha 1-antichymotrypsin (alpha 1-ACT)/ vimentin/ and lysosome#showed#positive reactions
#20126
high Confidence
Subject:
vimentin
(protein)
→
shows
→
Object:
positive_reaction
(Test results)
Original: Alpha 1-antichymotrypsin (alpha 1-ACT)/ vimentin/ and lysosome#showed#positive reactions
#20125
high Confidence
Subject:
alpha_1_antichymotrypsin
(protein)
→
shows
→
Object:
positive_reaction
(Test results)
Original: Alpha 1-antichymotrypsin (alpha 1-ACT)/ vimentin/ and lysosome#showed#positive reactions
#20123
high Confidence
Subject:
fine-needle_aspiration_cytology
(Diagnostic Methods)
→
reveals
→
Object:
invasive_ductal_carcinoma
(Tumor type)
Original: Fine-needle aspiration cytology#revealed#invasive ductal carcinoma
#20122
high Confidence
Subject:
cytologic_evaluation
(Diagnostic Methods)
→
achieves
→
Object:
diagnosis_of_pulmonary_metastasis
(Tumor type)
Original: Cytologic evaluation#achieved#diagnosis of pulmonary metastasis
#20121
high Confidence
Subject:
cytological_diagnosis
(Diagnostic Methods)
→
is_confirmed_by
→
Object:
pleomorphic_carcinoma
(Tumor type)
Original: Findings#confirmed#cytological diagnosis of pleomorphic carcinoma
#20117
high Confidence
Subject:
radiological_examination
(Imaging tests)
→
shows
→
Object:
compression_of_cervical_spinal_cord
(Imaging findings)
Original: radiological examination#showed#clivus bone destruction and compression of brain stem and cervical spinal cord
#20116
high Confidence
Subject:
radiological_examination
(Imaging tests)
→
shows
→
Object:
compression_of_brain_stem
(Imaging findings)
Original: radiological examination#showed#clivus bone destruction and compression of brain stem and cervical spinal cord
#20115
high Confidence
Subject:
radiological_examination
(Imaging tests)
→
shows
→
Object:
clivus_bone_destruction
(Imaging findings)
Original: radiological examination#showed#clivus bone destruction and compression of brain stem and cervical spinal cord
#20114
high Confidence
Subject:
INI1_gene
(Protein coding genes)
→
shows_genetic_abnormalities_in
→
Object:
tumor
(Tumor tissue)
Original: Four tumors#showed#genetic abnormalities involving the INI1 gene
#20113
high Confidence
Subject:
IVLBCL_tumor_cells
(Tumor cells)
→
express
→
Object:
PAX5
(Transcription Factors)
Original: IVLBCL tumor cells#express#CD20 and PAX5
#20112
high Confidence
Subject:
IVLBCL_tumor_cells
(Tumor cells)
→
express
→
Object:
CD20
(Membrane receptor protein)
Original: IVLBCL tumor cells#express#CD20 and PAX5
#20109
high Confidence
Subject:
patients
(patient)
→
are_diagnosed_with
→
Object:
Sertoli-stromal_cell_tumors
(Tumor)
Original: Patients#are diagnosed with#unclassified sex cord-stromal tumors or Sertoli-stromal cell tumors
#20108
high Confidence
Subject:
patients
(patient)
→
are_diagnosed_with
→
Object:
unclassified_sex_cord-stromal_tumors
(Tumor)
Original: Patients#are diagnosed with#unclassified sex cord-stromal tumors or Sertoli-stromal cell tumors
#20107
high Confidence
Subject:
fine_needle_aspiration_biopsy
(Diagnostic techniques)
→
is_used_to_analyze
→
Object:
renal_tumors_in_children
(Tumor)
Original: Fine needle aspiration biopsy#is used to analyze#renal tumors in children
#20103
high Confidence
Subject:
FNA_cytology
(Fine needle aspiration cytology)
→
shows_efficacy_in
→
Object:
presurgical_evaluation_of_testicular_masses
(Diagnostic Process)
Original: FNA cytology#shows#efficacy in presurgical evaluation of testicular masses
#20102
high Confidence
Subject:
fine_needle_aspiration_cytology
(Diagnostic techniques)
→
is_used_for
→
Object:
primary_hepatic_neoplasms
(Primary liver tumor)
Original: Fine-needle aspiration cytology#is used for#diagnosis of primary hepatic neoplasms
#20047
high Confidence
Subject:
PLCG2
(Enzymes)
→
is_identified_as
→
Object:
novel_biomarker_for_ccRCC
(Diagnostic markers)
Original: PLCG2#is identified as#a novel biomarker for ccRCC
#20039
high Confidence
Subject:
cytologic_findings
(Cytology)
→
included
→
Object:
neuroendocrine_tumor
(Tumor)
Original: Cytologic findings#included#hepatocellular/ adrenal/ and renal carcinomas/ melanoma/ mesothelioma/ and neuroendocrine tumors
#20038
high Confidence
Subject:
cytologic_findings
(Cytology)
→
included
→
Object:
mesothelioma
(Tumor)
Original: Cytologic findings#included#hepatocellular/ adrenal/ and renal carcinomas/ melanoma/ mesothelioma/ and neuroendocrine tumors
#20037
high Confidence
Subject:
cytologic_findings
(Cytology)
→
included
→
Object:
melanoma
(Tumor)
Original: Cytologic findings#included#hepatocellular/ adrenal/ and renal carcinomas/ melanoma/ mesothelioma/ and neuroendocrine tumors
#20036
high Confidence
Subject:
cytologic_findings
(Cytology)
→
included
→
Object:
renal_carcinoma
(Tumor)
Original: Cytologic findings#included#hepatocellular/ adrenal/ and renal carcinomas/ melanoma/ mesothelioma/ and neuroendocrine tumors
#20035
high Confidence
Subject:
cytologic_findings
(Cytology)
→
included
→
Object:
adrenal_carcinoma
(Tumor)
Original: Cytologic findings#included#hepatocellular/ adrenal/ and renal carcinomas/ melanoma/ mesothelioma/ and neuroendocrine tumors
#20034
high Confidence
Subject:
cytologic_findings
(Cytology)
→
included
→
Object:
hepatocellular_carcinoma
(Tumor)
Original: Cytologic findings#included#hepatocellular/ adrenal/ and renal carcinomas/ melanoma/ mesothelioma/ and neuroendocrine tumors
#20033
high Confidence
Subject:
Fine_needle_aspiration_cytology
(Diagnostic techniques)
→
diagnoses
→
Object:
Carcinoma_breast
(disease)
Original: 60 carcinoma breast cases#were diagnosed on#fine needle aspiration cytology
#20029
high Confidence
Subject:
Endometrial_adenocarcinoma
(Tumor type)
→
is_graded_by
→
Object:
nuclear_grading_system
(Rating system)
Original: Endometrial adenocarcinomas#are graded by#FIGO system and nuclear grading system
#20028
high Confidence
Subject:
Endometrial_adenocarcinoma
(Tumor type)
→
is_graded_by
→
Object:
FIGO_system
(Rating system)
Original: Endometrial adenocarcinomas#are graded by#FIGO system and nuclear grading system
#20010
high Confidence
Subject:
NUT_midline_carcinoma
(Tumor diseases)
→
has
→
Object:
characteristic_morphological_features
(Pathological characteristics)
Original: NMC#has#characteristic morphological features and positive immunostaining with NUT antibody
#19993
high Confidence
Subject:
MKI67
(Cell proliferation marker proteins)
→
is_used_to_assess
→
Object:
proliferation_in_carcinoma_in_situ
(Proliferation (carcinoma in situ))
Original: Ki-67#is used to assess#proliferation in high-grade dysplasia and carcinoma in situ in colorectal adenomas
#19992
high Confidence
Subject:
MKI67
(Cell proliferation marker proteins)
→
is_used_to_assess
→
Object:
proliferation_in_high-grade_dysplasia
(Proliferation (high-grade intraepithelial neoplasia))
Original: Ki-67#is used to assess#proliferation in high-grade dysplasia and carcinoma in situ in colorectal adenomas
#19977
middle Confidence
Subject:
nuclear_molding
(Cell morphology)
→
shows
→
Object:
SCC_cases
(Tumor)
Original: Salt and pepper chromatin/ small cell size/ and nuclear molding#showed#90% sensitivity and 70% specificity for SCC cases
#19976
middle Confidence
Subject:
small_cell_size
(Cell morphology)
→
shows
→
Object:
SCC_cases
(Tumor)
Original: Salt and pepper chromatin/ small cell size/ and nuclear molding#showed#90% sensitivity and 70% specificity for SCC cases
#19975
middle Confidence
Subject:
salt_and_pepper_chromatin
(Cell morphology)
→
shows
→
Object:
SCC_cases
(Tumor)
Original: Salt and pepper chromatin/ small cell size/ and nuclear molding#showed#90% sensitivity and 70% specificity for SCC cases
#19973
middle Confidence
Subject:
histological_features
(Histological characteristics)
→
are_vital_for
→
Object:
differentiating_malignant_pleural_mesothelioma
(Disease phenotype)
Original: Histological features on plain tissue sections#are vital for#differentiating benign pleural disease from malignant pleural mesothelioma
#19972
middle Confidence
Subject:
histological_features
(Histological characteristics)
→
are_vital_for
→
Object:
differentiating_benign_pleural_disease
(Disease phenotype)
Original: Histological features on plain tissue sections#are vital for#differentiating benign pleural disease from malignant pleural mesothelioma
#19968
middle Confidence
Subject:
AgNORs
(Molecular markers)
→
serve_as
→
Object:
index_of_invasiveness
(Diagnostic indicators)
Original: Argyrophilic nucleolar organizer region proteins (AgNORs)#serve as#index of clinical and radiological invasiveness in pituitary adenomas
#19961
middle Confidence
Subject:
Interdigitating_dendritic_cell_tumor
(Rare tumors)
→
has_been_reported_in
→
Object:
extranodal_sites
(Ectopic site)
Original: Interdigitating dendritic cell tumor (IDCT)#has been reported in#extranodal sites
#19960
middle Confidence
Subject:
normal_myoepithelial_cells
(Cell Type)
→
are_identified_by
→
Object:
immunostaining_for_p63
(Immunoassay)
Original: normal myoepithelial cells#are identified by#immunostaining for p63
#19942
middle Confidence
Subject:
PD-L1_expression
(Protein expression)
→
is_associated_with
→
Object:
marked_nuclear_pleomorphism
(Morphological characteristics)
Original: Higher PD-L1 expression#is associated with#marked nuclear pleomorphism and coarse chromatin pattern
#19929
middle Confidence
Subject:
electron_microscopy
(Electron microscopy)
→
supports
→
Object:
diagnosis
(Diagnostic outcome)
Original: Classic electron microscopic findings#can support#the diagnosis
#19928
middle Confidence
Subject:
key_features
(Key Features)
→
discriminate_between
→
Object:
nephrogenic_adenoma
(Benign lesions)
Original: Key features#discriminate between#nephrogenic adenoma-like clear cell adenocarcinoma and nephrogenic adenoma
#19927
middle Confidence
Subject:
key_features
(Key Features)
→
discriminate_between
→
Object:
nephrogenic_adenoma-like_clear_cell_adenocarcinoma
(Tumor type)
Original: Key features#discriminate between#nephrogenic adenoma-like clear cell adenocarcinoma and nephrogenic adenoma
#19926
middle Confidence
Subject:
prominent_nucleoli
(Nuclear morphology)
→
are_a_feature_of
→
Object:
atypical_adenomatous_hyperplasia
(Adenomatous hyperplasia of the prostate)
Original: Prominent nucleoli#are a feature of#AAH
#19924
middle Confidence
Subject:
chronic_lymphoid_leukemia
(Tumor type)
→
is_characterized_by
→
Object:
B-lymphocyte_proliferation
(Cellular Processes)
Original: chronic lymphoid leukemia#was characterized by#proliferation of B-lymphocytes
#19920
middle Confidence
Subject:
CD20
(Differentiation antigen)
→
is
→
Object:
diagnostic_aid_in_T-cell_lineage_neoplasms
(Diagnostic markers)
Original: CD20 positivity#is#a diagnostic aid in neoplasms of T-cell lineage
#19854
middle Confidence
Subject:
NOR_index
(Nucleolar Organizer Zone Index)
→
has_diagnostic_value_in
→
Object:
neoplastic_disease
(Neoplastic diseases)
Original: NOR index#correlates with#cellular proliferation and has diagnostic and prognostic value in neoplastic disease
#19836
middle Confidence
Subject:
Spindle_cells
(Cell Type)
→
are_positive_for
→
Object:
S100
(protein)
Original: Testicular juvenile granulosa cell tumor#disclosed#vimentin/ alpha-inhibin/ and S-100-positive spindle cells
#19835
middle Confidence
Subject:
Spindle_cells
(Cell Type)
→
are_positive_for
→
Object:
alpha-inhibin
(protein)
Original: Testicular juvenile granulosa cell tumor#disclosed#vimentin/ alpha-inhibin/ and S-100-positive spindle cells
#19834
middle Confidence
Subject:
Spindle_cells
(Cell Type)
→
are_positive_for
→
Object:
vimentin
(protein)
Original: Testicular juvenile granulosa cell tumor#disclosed#vimentin/ alpha-inhibin/ and S-100-positive spindle cells
#19827
middle Confidence
Subject:
Tumor
(Tumor)
→
is_diagnosed_as
→
Object:
canine_clear_cell_adnexal_carcinoma
(Tumor type)
Original: Tumor#is diagnosed as#canine clear cell adnexal carcinoma
#19821
middle Confidence
Subject:
anisocytosis
(Cell phenotype)
→
indicates
→
Object:
prostatic_duct_adenocarcinoma
(Prostatic ductal adenocarcinoma)
Original: Anisocytosis#showed#40% probability of PDAC presence
#19814
middle Confidence
Subject:
Primary_colorectal_T-cell_lymphoma
(Tumor diseases)
→
is_associated_with
→
Object:
suppressor_T-cell_phenotype
(Immune cell types)
Original: Primary colorectal T-cell lymphoma#is associated with#cytotoxic/suppressor T-cell phenotype
#19813
middle Confidence
Subject:
Primary_colorectal_T-cell_lymphoma
(Tumor diseases)
→
is_associated_with
→
Object:
cytotoxic_T-cell_phenotype
(Immune cell types)
Original: Primary colorectal T-cell lymphoma#is associated with#cytotoxic/suppressor T-cell phenotype
#19759
middle Confidence
Subject:
AgNORs
(Nucleolus-associated organic silver stain)
→
have_diagnostic_value_in
→
Object:
urothelial_bladder_lesions
(disease)
Original: AgNORs#have diagnostic value in#urothelial bladder lesions
#19737
middle Confidence
Subject:
statistically_significant_differences
(Statistical difference)
→
were_found_between
→
Object:
groups_with_squamous_cell_carcinomas
(Pathological grouping)
Original: Statistically significant differences#were found between#groups with mild dysplasia/ severe dysplasia/ and squamous cell carcinomas
#19736
middle Confidence
Subject:
statistically_significant_differences
(Statistical difference)
→
were_found_between
→
Object:
groups_with_severe_dysplasia
(Pathological grouping)
Original: Statistically significant differences#were found between#groups with mild dysplasia/ severe dysplasia/ and squamous cell carcinomas
#19735
middle Confidence
Subject:
statistically_significant_differences
(Statistical difference)
→
were_found_between
→
Object:
groups_with_mild_dysplasia
(Pathological grouping)
Original: Statistically significant differences#were found between#groups with mild dysplasia/ severe dysplasia/ and squamous cell carcinomas
#19699
middle Confidence
Subject:
p53
(Transcription Factors)
→
correlates_with
→
Object:
PCNA_labeling_index
(Cell proliferation markers)
Original: p53 immunopositivity#correlates with#PCNA labeling index in thymoma
#19698
middle Confidence
Subject:
nucleolar_organizer_regions
(Nucleolar organizer region)
→
represent
→
Object:
tumor_proliferation_marker
(Tumor proliferation markers)
Original: nucleolar organizer regions (NORs)#represent#valuable markers of tumor proliferation
#19670
middle Confidence
Subject:
atypical_adenomatous_hyperplasia
(Benign lesions)
→
diagnostic_belief_score
→
Object:
1
(Diagnostic score)
Original: Belief for AAH#was#1.0 after analysis of five nucleolar features
#19669
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_focally_positive_for
→
Object:
CD4
(T cell surface molecules)
Original: Tumor cells#were focally positive for#lysozyme/ alpha-1 antitrypsin/ and CD4
#19668
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_focally_positive_for
→
Object:
SERPINA1
(Serine protease inhibitors)
Original: Tumor cells#were focally positive for#lysozyme/ alpha-1 antitrypsin/ and CD4
#19667
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_focally_positive_for
→
Object:
LYZ
(Lysozyme)
Original: Tumor cells#were focally positive for#lysozyme/ alpha-1 antitrypsin/ and CD4
#19666
middle Confidence
Subject:
sheet-like_growth
(Growth pattern)
→
suggest
→
Object:
atypical_meningioma
(disease)
Original: nuclear anaplasia/ macronucleoli/ mitotic activity/ and sheet-like growth#suggest#atypical meningioma
#19665
middle Confidence
Subject:
mitotic_activity
(Cell division activity)
→
suggest
→
Object:
atypical_meningioma
(disease)
Original: nuclear anaplasia/ macronucleoli/ mitotic activity/ and sheet-like growth#suggest#atypical meningioma
#19664
middle Confidence
Subject:
macronucleoli
(Abnormal nucleoli)
→
suggest
→
Object:
atypical_meningioma
(disease)
Original: nuclear anaplasia/ macronucleoli/ mitotic activity/ and sheet-like growth#suggest#atypical meningioma
#19663
middle Confidence
Subject:
nuclear_anaplasia
(Nuclear abnormalities)
→
suggest
→
Object:
atypical_meningioma
(disease)
Original: nuclear anaplasia/ macronucleoli/ mitotic activity/ and sheet-like growth#suggest#atypical meningioma
#19657
middle Confidence
Subject:
high-grade_lesion
(Tumor pathological grade)
→
shows
→
Object:
vimentin
(Intermediate filament protein)
Original: high-grade lesion#shows#diffuse expression of cyclin D1 and vimentin
#19656
middle Confidence
Subject:
high-grade_lesion
(Tumor pathological grade)
→
shows
→
Object:
cyclin_D1
(Cell cycle proteins)
Original: high-grade lesion#shows#diffuse expression of cyclin D1 and vimentin
#19651
middle Confidence
Subject:
Small_cell_carcinoma
(Tumor)
→
was_diagnosed_from
→
Object:
clinical_course
(Clinical course)
Original: Small cell carcinoma#was diagnosed from#histological features and clinical course
#19650
middle Confidence
Subject:
Small_cell_carcinoma
(Tumor)
→
was_diagnosed_from
→
Object:
histological_features
(Pathological characteristics)
Original: Small cell carcinoma#was diagnosed from#histological features and clinical course
#19618
middle Confidence
Subject:
biopsy_of_lesions
(Tissue biopsy)
→
confirmed
→
Object:
cytologic_diagnosis
(Cytological diagnosis)
Original: biopsy of lesions#confirmed#cytologic diagnoses
#19608
middle Confidence
Subject:
Findings
(Clinical findings)
→
raise_differential_of
→
Object:
medullary_carcinoma
(Tumor)
Original: Findings#raised the differential of#medullary carcinoma
#19607
middle Confidence
Subject:
Findings
(Clinical findings)
→
raise_differential_of
→
Object:
follicular_neoplasm
(Tumor)
Original: Findings#raised the differential of#follicular neoplasm
#19606
middle Confidence
Subject:
Findings
(Clinical findings)
→
raise_differential_of
→
Object:
papillary_thyroid_carcinoma
(Tumor)
Original: Findings#raised the differential of#papillary thyroid carcinoma
#19605
middle Confidence
Subject:
Chromogranin
(Secretory granule protein)
→
is_strongly_expressed_in
→
Object:
tumor_cells
(Tumor cells)
Original: Tumor cells#strongly expressed#CD99/ FLI1/ and chromogranin
#19604
middle Confidence
Subject:
FLI1
(Transcription Factors)
→
is_strongly_expressed_in
→
Object:
tumor_cells
(Tumor cells)
Original: Tumor cells#strongly expressed#CD99/ FLI1/ and chromogranin
#19603
middle Confidence
Subject:
CD99
(Leukocyte differentiation antigen)
→
is_strongly_expressed_in
→
Object:
tumor_cells
(Tumor cells)
Original: Tumor cells#strongly expressed#CD99/ FLI1/ and chromogranin
#19600
middle Confidence
Subject:
INSM1
(Transcription Factors)
→
is_positive_in
→
Object:
80_percent_cases
(Case ratio)
Original: Insulinoma-associated protein 1 (INSM1)#is positive in#80% cases
#19599
middle Confidence
Subject:
IDH2_R172_mutation
(Gene mutation)
→
occurs_in
→
Object:
olfactory_neuroblastoma
(Tumor type)
Original: IDH2 R172 mutations#occur in#sinonasal undifferentiated carcinoma (SNUC)/ large-cell neuroendocrine carcinoma (LCNEC)/ sinonasal adenocarcinomas/ and olfactory neuroblastoma (ONB)
#19598
middle Confidence
Subject:
IDH2_R172_mutation
(Gene mutation)
→
occurs_in
→
Object:
sinonasal_adenocarcinoma
(Tumor type)
Original: IDH2 R172 mutations#occur in#sinonasal undifferentiated carcinoma (SNUC)/ large-cell neuroendocrine carcinoma (LCNEC)/ sinonasal adenocarcinomas/ and olfactory neuroblastoma (ONB)
#19589
middle Confidence
Subject:
tumors
(Tumor)
→
were_reactive_with
→
Object:
Ki-67
(Proliferation markers)
Original: Tumors#were reactive with#inhibin/ vimentin/ CK5/ p53/ and Ki-67
#19588
middle Confidence
Subject:
tumors
(Tumor)
→
were_reactive_with
→
Object:
p53
(Tumor suppressor proteins)
Original: Tumors#were reactive with#inhibin/ vimentin/ CK5/ p53/ and Ki-67
#19587
middle Confidence
Subject:
tumors
(Tumor)
→
were_reactive_with
→
Object:
CK5
(Marker Protein)
Original: Tumors#were reactive with#inhibin/ vimentin/ CK5/ p53/ and Ki-67
#19586
middle Confidence
Subject:
tumors
(Tumor)
→
were_reactive_with
→
Object:
vimentin
(Marker Protein)
Original: Tumors#were reactive with#inhibin/ vimentin/ CK5/ p53/ and Ki-67
#19585
middle Confidence
Subject:
tumors
(Tumor)
→
were_reactive_with
→
Object:
inhibin
(Marker Protein)
Original: Tumors#were reactive with#inhibin/ vimentin/ CK5/ p53/ and Ki-67
#19578
middle Confidence
Subject:
molecular_findings_in_tumor_samples
(Molecular test results)
→
correlates_with
→
Object:
histopathologic_tumor_characteristics
(Pathological characteristics)
Original: Molecular findings in tumor samples#correlated with#prognosis and histopathologic tumor characteristics
#19568
middle Confidence
Subject:
malignant_rhabdoid_tumor
(Tumor type)
→
was_located_in
→
Object:
left_forehead_region
(Anatomical location)
Original: Primary malignant rhabdoid tumor (MRT)#was located in#left forehead region of an 8-mo-old female
#19539
middle Confidence
Subject:
Tumor
(Tumor tissue)
→
was_positive_for
→
Object:
vimentin
(Protein markers)
Original: Tumor#was positive for#epithelial membrane antigen and vimentin
#19538
middle Confidence
Subject:
Tumor
(Tumor tissue)
→
was_positive_for
→
Object:
epithelial_membrane_antigen
(Protein markers)
Original: Tumor#was positive for#epithelial membrane antigen and vimentin
#19537
middle Confidence
Subject:
Immunohistochemical_findings
(Immunohistochemical findings)
→
led_to
→
Object:
diagnosis_of_cervical_spinal_cord_oligodendroglioma
(Diagnosis conclusion)
Original: Histologic and immunohistochemical findings#led to#diagnosis of cervical spinal cord oligodendroglioma
#19536
middle Confidence
Subject:
Histologic_findings
(Histological findings)
→
led_to
→
Object:
diagnosis_of_cervical_spinal_cord_oligodendroglioma
(Diagnosis conclusion)
Original: Histologic and immunohistochemical findings#led to#diagnosis of cervical spinal cord oligodendroglioma
#19534
middle Confidence
Subject:
mucinous_fibroplasia
(Tissue morphology)
→
was_verified_as
→
Object:
carcinoma
(Tumor)
Original: Mucinous fibroplasia#was verified as#carcinoma with immunohistochemistry
#19533
middle Confidence
Subject:
PNI
(Tissue microenvironment characteristics)
→
was_verified_as
→
Object:
carcinoma
(Tumor)
Original: PNI#was verified as#carcinoma with immunohistochemistry
#19532
middle Confidence
Subject:
HBV_markers
(Serum biomarkers)
→
has_adjunctive_role_in
→
Object:
HCC
(Tumor type)
Original: The cytologic features of fine needle aspiration biopsies from well- and poorly differentiated HCC#were reviewed and#the adjunctive role of serum AFP/ HBV markers and radiologic findings evaluated
#19531
middle Confidence
Subject:
cytologic_features_of_FNA
(Cytological characteristics)
→
were_reviewed_and
→
Object:
poorly_differentiated_HCC
(Tumor type)
Original: The cytologic features of fine needle aspiration biopsies from well- and poorly differentiated HCC#were reviewed and#the adjunctive role of serum AFP/ HBV markers and radiologic findings evaluated
#19530
middle Confidence
Subject:
cytologic_features_of_FNA
(Cytological characteristics)
→
were_reviewed_and
→
Object:
well_differentiated_HCC
(Tumor type)
Original: The cytologic features of fine needle aspiration biopsies from well- and poorly differentiated HCC#were reviewed and#the adjunctive role of serum AFP/ HBV markers and radiologic findings evaluated
#19519
middle Confidence
Subject:
presence_of_prostatic_adenocarcinoma_in_urine
(Diagnostic markers)
→
implies
→
Object:
high_stage_tumor
(Disease phenotype)
Original: Presence of prostatic adenocarcinoma in urine#implies#high stage tumor
#19518
middle Confidence
Subject:
prominent_nucleoli
(Cell morphology)
→
is_key_feature_of
→
Object:
prostatic_adenocarcinoma_in_urine
(Tumor type)
Original: Key features for prostatic adenocarcinoma in urine#include#clustering/ increased nuclear to cytoplasmic ratio/ and prominent nucleoli
#19517
middle Confidence
Subject:
increased_nuclear_to_cytoplasmic_ratio
(Cell morphology)
→
is_key_feature_of
→
Object:
prostatic_adenocarcinoma_in_urine
(Tumor type)
Original: Key features for prostatic adenocarcinoma in urine#include#clustering/ increased nuclear to cytoplasmic ratio/ and prominent nucleoli
#19516
middle Confidence
Subject:
clustering
(Cell morphology)
→
is_key_feature_of
→
Object:
prostatic_adenocarcinoma_in_urine
(Tumor type)
Original: Key features for prostatic adenocarcinoma in urine#include#clustering/ increased nuclear to cytoplasmic ratio/ and prominent nucleoli
#19506
middle Confidence
Subject:
tumor
(Tumor)
→
is_diagnosed_as
→
Object:
osteoclast_like_giant_cell_tumor_of_pancreas
(Tumor type)
Original: tumor#is diagnosed as#osteoclast-like giant cell tumor of the pancreas
#19497
middle Confidence
Subject:
PD-L1_expression
(Protein expression)
→
is_positive_in
→
Object:
36.7_percent_cases
(Case ratio)
Original: PD-L1 expression#was positive in#33 of 90 cases (36.7%)
#19494
middle Confidence
Subject:
Lesions
(Lesions)
→
correlated_histologically_with
→
Object:
follicular_adenomas_with_fine_chromatin_pattern
(Tumor type)
Original: Lesions#correlated histologically with#PTC and follicular adenomas with a fine chromatin pattern
#19493
middle Confidence
Subject:
Lesions
(Lesions)
→
correlated_histologically_with
→
Object:
papillary_thyroid_carcinoma_with_fine_chromatin_pattern
(Tumor type)
Original: Lesions#correlated histologically with#PTC and follicular adenomas with a fine chromatin pattern
#19492
middle Confidence
Subject:
Fine_needle_aspiration_biopsy
(Fine needle aspiration biopsy)
→
was_reviewed_with
→
Object:
histologic_correlation
(Histological correlation)
Original: Fine needle aspiration biopsies (FNAB)#were reviewed with#histologic correlation
#19491
middle Confidence
Subject:
Histological_assessment
(Histological evaluation)
→
diagnoses
→
Object:
multinodular_goitre_with_degenerate_changes
(Types of thyroid disease)
Original: Histological assessment#diagnosed#papillary carcinoma/ Hurthle cell carcinoma/ and multinodular goitre with degenerate changes
#19483
middle Confidence
Subject:
Cytologic_features
(Cytological characteristics)
→
are_indicative_of
→
Object:
malignant_neoplasm
(Tumor type)
Original: Cytologic features#are indicative of#a malignant neoplasm
#19478
middle Confidence
Subject:
CD10_immunohistochemistry
(Immunohistochemistry)
→
facilitates
→
Object:
accurate_diagnosis_of_metastatic_RCC_in_adrenal_FNA
(Diagnostic Process)
Original: cytomorphology and CD10 immunohistochemistry#facilitate#accurate diagnosis of metastatic RCC in adrenal FNA
#19477
middle Confidence
Subject:
Cytomorphology
(Cell morphology)
→
facilitates
→
Object:
accurate_diagnosis_of_metastatic_RCC_in_adrenal_FNA
(Diagnostic Process)
Original: cytomorphology and CD10 immunohistochemistry#facilitate#accurate diagnosis of metastatic RCC in adrenal FNA
#19472
middle Confidence
Subject:
extracellular_mucin
(Morphological characteristics)
→
mimics
→
Object:
prostate_cancer
(Tumor diseases)
Original: Features mimicking prostate cancer#include#blue-tinged intraluminal mucinous secretions/ prominent nucleoli/ mitotic activity/ extracellular mucin
#19471
middle Confidence
Subject:
mitotic_activity
(Cellular Processes)
→
mimics
→
Object:
prostate_cancer
(Tumor diseases)
Original: Features mimicking prostate cancer#include#blue-tinged intraluminal mucinous secretions/ prominent nucleoli/ mitotic activity/ extracellular mucin
#19470
middle Confidence
Subject:
prominent_nucleoli
(Morphological characteristics)
→
mimics
→
Object:
prostate_cancer
(Tumor diseases)
Original: Features mimicking prostate cancer#include#blue-tinged intraluminal mucinous secretions/ prominent nucleoli/ mitotic activity/ extracellular mucin
#19469
middle Confidence
Subject:
blue-tinged_intraluminal_mucinous_secretions
(Morphological characteristics)
→
mimics
→
Object:
prostate_cancer
(Tumor diseases)
Original: Features mimicking prostate cancer#include#blue-tinged intraluminal mucinous secretions/ prominent nucleoli/ mitotic activity/ extracellular mucin
#19468
middle Confidence
Subject:
rectal_tissue
(Organization Type)
→
is_questioned_as
→
Object:
prostate_cancer
(Tumor diseases)
Original: We#evaluated#16 prostate needle biopsies where rectal tissue was questioned as prostate cancer
#19465
middle Confidence
Subject:
esophageal_tumor_biopsy
(Tumor samples)
→
showed
→
Object:
small_cell_carcinoma_with_hyperchromatic_nuclei
(Tumor type)
Original: esophageal tumor biopsy#showed#a small cell carcinoma with hyperchromatic nuclei
#19444
middle Confidence
Subject:
stepwise_classification_of_thymoma_with_FNAB
(Diagnostic techniques)
→
may_be_useful_for
→
Object:
patients_without_invasive_diagnosis
(Patient characteristics)
Original: stepwise classification of thymoma with FNAB#may be useful#for patients without invasive diagnosis
#19441
middle Confidence
Subject:
imaging_examination
(Medical examination)
→
did_not_find
→
Object:
other_primary_lesions
(Primary tumor)
Original: systemic and imaging examinations#did not find#any other primary lesions
#19440
middle Confidence
Subject:
systemic_examination
(Medical examination)
→
did_not_find
→
Object:
other_primary_lesions
(Primary tumor)
Original: systemic and imaging examinations#did not find#any other primary lesions
#19437
middle Confidence
Subject:
biopsy
(Histological examination)
→
reveals
→
Object:
typical_trichoepithelioma
(Tumor)
Original: Biopsy#revealed#a typical trichoepithelioma
#19435
middle Confidence
Subject:
case
(Case)
→
is_diagnosed_as
→
Object:
hepatoid_carcinoma_of_extrahepatic_duct
(disease)
Original: Case#is diagnosed as#hepatoid carcinoma of the extrahepatic duct
#19434
middle Confidence
Subject:
FDC
(Follicular dendritic cells)
→
highlighted_by
→
Object:
CD68
(Cell surface markers)
Original: FDC#highlighted by#CD21/ CD35/ R4/23/ Ki-M4/ CNA.42/ CD68
#19433
middle Confidence
Subject:
FDC
(Follicular dendritic cells)
→
highlighted_by
→
Object:
CNA.42
(Cell surface markers)
Original: FDC#highlighted by#CD21/ CD35/ R4/23/ Ki-M4/ CNA.42/ CD68
#19432
middle Confidence
Subject:
FDC
(Follicular dendritic cells)
→
highlighted_by
→
Object:
Ki-M4
(Cell surface markers)
Original: FDC#highlighted by#CD21/ CD35/ R4/23/ Ki-M4/ CNA.42/ CD68
#19431
middle Confidence
Subject:
FDC
(Follicular dendritic cells)
→
highlighted_by
→
Object:
R4/23
(Cell surface markers)
Original: FDC#highlighted by#CD21/ CD35/ R4/23/ Ki-M4/ CNA.42/ CD68
#19429
middle Confidence
Subject:
GEA
(Tumor type)
→
can_be_identified_based_on
→
Object:
flat_honeycomb_like_sheets_of_tumor_cells_with_vesicular_nuclei_prominent_nucleoli_and_abundant_vacuolated_cytoplasm
(Diagnostic morphological features)
Original: GEA#can be identified based on#flat/ honeycomb-like sheets of tumor cells with vesicular nuclei/ prominent nucleoli/ and abundant vacuolated cytoplasm
#19426
middle Confidence
Subject:
tumor
(Tumor)
→
is_classified_as
→
Object:
immunoblastic_lymphoma
(Tumor type)
Original: tumor#is classified as#immunoblastic lymphoma
#19421
middle Confidence
Subject:
early-stage_renal-cell_carcinoma
(Tumor type)
→
is_more_frequently_diagnosed_due_to
→
Object:
advanced_radiologic_techniques
(Diagnostic techniques)
Original: Early-stage renal-cell carcinoma#is more frequently diagnosed due to#more frequent use of advanced radiologic techniques
#19420
middle Confidence
Subject:
Thirty-nine_of_42_specimens
(Sample Group)
→
were_correctly_identified_as
→
Object:
serous_neoplasm
(Tumor type)
Original: Thirty-nine of 42 specimens#were correctly identified as#RM or serous neoplasm
#19419
middle Confidence
Subject:
Thirty-nine_of_42_specimens
(Sample Group)
→
were_correctly_identified_as
→
Object:
RM
(Cell Type)
Original: Thirty-nine of 42 specimens#were correctly identified as#RM or serous neoplasm
#19415
middle Confidence
Subject:
needle_biopsy_of_ilium
(Diagnostic techniques)
→
diagnoses
→
Object:
poorly_differentiated_adenocarcinoma
(Tumor diseases)
Original: needle biopsy of ilium#diagnosed#poorly differentiated adenocarcinoma
#19414
middle Confidence
Subject:
cytologic_smears
(Cytology specimens)
→
revealed
→
Object:
loosely_dispersed_spindle_cells
(Cell Type)
Original: Cytologic smears#revealed#a loosely dispersed population of spindle cells with prominent nucleoli
#19413
middle Confidence
Subject:
cytologic_study_of_ascites
(Diagnostic techniques)
→
determines
→
Object:
clinical_staging_of_malignant_ovarian_tumors
(Clinical staging)
Original: Cytologic study of ascites#determines#clinical staging of malignant ovarian tumors
#19373
middle Confidence
Subject:
Cerebrospinal fluid
(body fluid)
→
contained
→
Object:
abundant malignant cells with rhabdoid phenotype
(Tumor cells)
Original: Cerebrospinal fluid#contained#abundant malignant cells with rhabdoid phenotype
#19364
middle Confidence
Subject:
morphological_features
(Cell morphology)
→
are_statistically_associated_with
→
Object:
adenocarcinoma
(Disease phenotype)
Original: Features#are statistically associated with#adenocarcinoma
#19363
middle Confidence
Subject:
EGFR_mutation
(Gene mutation)
→
is_associated_with
→
Object:
bronchioloalveolar_subtype
(Disease classification)
Original: EGFR mutations#are associated with#bronchioloalveolar subtype
#19355
middle Confidence
Subject:
AgNOR_score
(Detection indicators)
→
is_valuable_in
→
Object:
aiding_differential_diagnosis_between_malignant_lesions
(Diagnostic Process)
Original: AgNOR score#is valuable in#aiding differential diagnosis between benign and malignant lesions
#19354
middle Confidence
Subject:
AgNOR_score
(Detection indicators)
→
is_valuable_in
→
Object:
aiding_differential_diagnosis_between_benign_lesions
(Diagnostic Process)
Original: AgNOR score#is valuable in#aiding differential diagnosis between benign and malignant lesions
#19353
middle Confidence
Subject:
Silver_staining_for_AgNOR
(Staining method)
→
is_useful_for
→
Object:
differential_diagnosis_between_malignant_cells
(Diagnostic Process)
Original: Silver staining for AgNOR#is useful for#differential diagnosis between benign and malignant cells
#19352
middle Confidence
Subject:
Silver_staining_for_AgNOR
(Staining method)
→
is_useful_for
→
Object:
differential_diagnosis_between_benign_cells
(Diagnostic Process)
Original: Silver staining for AgNOR#is useful for#differential diagnosis between benign and malignant cells
#19351
middle Confidence
Subject:
angiosarcoma
(Tumor type)
→
is_diagnosed_by
→
Object:
fine_needle_aspiration
(Diagnostic techniques)
Original: angiosarcoma#is diagnosed by#fine needle aspiration
#19350
middle Confidence
Subject:
BBC
(Cytological testing methods)
→
is_sensitive_for
→
Object:
detecting_PSC
(Diagnostic Process)
Original: BBC#is sensitive for#detecting cholangiocarcinoma in PSC patients
#19349
middle Confidence
Subject:
discohesion
(Cell morphological characteristics)
→
is
→
Object:
predictive_feature_in_diagnosing_malignancy
(Diagnostic features)
Original: nuclear/cytoplasmic ratio/ prominent nucleoli/ nuclear membrane irregularities/ and discohesion#are#predictive features in diagnosing malignancy
#19348
middle Confidence
Subject:
nuclear_membrane_irregularities
(Cell morphological characteristics)
→
is
→
Object:
predictive_feature_in_diagnosing_malignancy
(Diagnostic features)
Original: nuclear/cytoplasmic ratio/ prominent nucleoli/ nuclear membrane irregularities/ and discohesion#are#predictive features in diagnosing malignancy
#19347
middle Confidence
Subject:
prominent_nucleoli
(Cell morphological characteristics)
→
is
→
Object:
predictive_feature_in_diagnosing_malignancy
(Diagnostic features)
Original: nuclear/cytoplasmic ratio/ prominent nucleoli/ nuclear membrane irregularities/ and discohesion#are#predictive features in diagnosing malignancy
#19346
middle Confidence
Subject:
nuclear_cytoplasmic_ratio
(Cell morphological characteristics)
→
is
→
Object:
predictive_feature_in_diagnosing_malignancy
(Diagnostic features)
Original: nuclear/cytoplasmic ratio/ prominent nucleoli/ nuclear membrane irregularities/ and discohesion#are#predictive features in diagnosing malignancy
#19331
middle Confidence
Subject:
Prominent nucleoli
(Cell nucleolus morphology)
→
shows_high_specificity_for
→
Object:
cholangiocarcinoma
(Tumor)
Original: Prominent nucleoli#show#high specificity for cholangiocarcinoma
#19316
middle Confidence
Subject:
presence_of_nucleoli
(Nucleolus exists)
→
helps_in
→
Object:
diagnosis_of_thyroid_carcinoma
(Disease diagnosis)
Original: Nuclear structure and presence of nucleoli#help in#diagnosis of thyroid carcinoma
#19315
middle Confidence
Subject:
nuclear_structure
(Nuclear structure)
→
helps_in
→
Object:
diagnosis_of_thyroid_carcinoma
(Disease diagnosis)
Original: Nuclear structure and presence of nucleoli#help in#diagnosis of thyroid carcinoma
#19311
middle Confidence
Subject:
schwannomas_in_pancreatic_head
(Tumor)
→
are
→
Object:
rare_benign_nonrecurring_mesenchymal_neoplasms
(Disease phenotype)
Original: Schwannomas occurring in the pancreatic head#are#rare benign non-recurring mesenchymal neoplasms
#19308
middle Confidence
Subject:
morphologic_features
(Morphological characteristics)
→
describe
→
Object:
malignant_melanoma_of_soft_parts
(Tumor type)
Original: Malignant melanoma of soft parts (MMSP)#is described by#morphologic features in cytology specimens
#19300
middle Confidence
Subject:
Tumor
(Tumor tissue)
→
shows
→
Object:
proliferation_of_atypical_epithelial_cells_with_apocrine_differentiation_and_stromal_invasion
(Cellular process phenotype)
Original: Tumor#revealed#proliferation of atypical epithelial cells with apocrine differentiation and stromal invasion
#19297
middle Confidence
Subject:
clinical_findings
(Clinical manifestations)
→
suggest
→
Object:
angiosarcoma
(Tumor type)
Original: Clinical findings#suggested#angiosarcoma in patients with irradiation and chronic lymphedema
#19291
middle Confidence
Subject:
Cytoarchitectural_complexity
(Cellular morphology complexity)
→
warrants
→
Object:
HGD_or_carcinoma_classification
(Pathological diagnosis)
Original: Cytoarchitectural complexity#warrants#HGD/carcinoma classification
#19290
middle Confidence
Subject:
Cytoarchitectural_atypia
(Abnormal cell morphology)
→
qualifies_as
→
Object:
high-grade_dysplasia
(Pathological diagnosis)
Original: Cytoarchitectural atypia#qualified as#high-grade dysplasia
#19278
middle Confidence
Subject:
metastases
(Disease phenotype)
→
showed_positive_staining_for
→
Object:
S-100_protein
(protein)
Original: Metastases#showed positive staining for#S-100 protein
#19277
middle Confidence
Subject:
Lesion
(Pathological entity)
→
shows
→
Object:
circumscribed_proliferation_of_basaloid_cells
(Histological characteristics)
Original: Lesion#shows#circumscribed proliferation of basaloid cells
#19276
middle Confidence
Subject:
4-year-old_male_child
(Patient characteristics)
→
presents_with
→
Object:
recurrent_lesion_on_left_cheek
(Clinical symptoms)
Original: A 4-year-old male child#presents with#recurrent lesions on his left cheek
#19275
middle Confidence
Subject:
Oral_SF
(Disease phenotype)
→
is_a_unique_entity_and_should_be_differentiated_from
→
Object:
benign_fibrous_lesions
(Disease phenotype)
Original: Findings#confirm that#oral SF represents a unique entity and should be differentiated from benign fibrous lesions
#19267
middle Confidence
Subject:
fine_needle_aspiration_cytology
(Cytology)
→
is_useful_for
→
Object:
diagnostic_intradermal_cystic_lesions
(disease)
Original: FNAC#is useful for#diagnosing intradermal cystic lesions before surgery
#19263
middle Confidence
Subject:
malignant_gastrointestinal_neuroectodermal_tumor
(Tumor diseases)
→
needs_to_be_distinguished_from
→
Object:
small_blue_round_and_spindle_cell_tumors_of_gut
(Tumor diseases)
Original: malignant gastrointestinal neuroectodermal tumor#needs to be distinguished from#other small blue round and spindle cell tumors in the gut
#19254
middle Confidence
Subject:
malignant_epithelioid_hemangioendothelioma
(Tumor type)
→
diagnosed_by
→
Object:
fine_needle_aspiration_cytology
(Diagnostic techniques)
Original: malignant epithelioid hemangioendothelioma#was diagnosed by#fine needle aspiration cytology
#19244
middle Confidence
Subject:
immunocytochemical_features
(Immunocytochemical characteristics)
→
suggest
→
Object:
DSRCT
(Tumor type)
Original: Cytologic and immunocytochemical features#suggest#diagnosis of DSRCT on fine needle aspiration cytology samples
#19243
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
suggest
→
Object:
DSRCT
(Tumor type)
Original: Cytologic and immunocytochemical features#suggest#diagnosis of DSRCT on fine needle aspiration cytology samples
#19236
middle Confidence
Subject:
ultrastructural_investigation
(Detection Technology)
→
revealed
→
Object:
dysgerminoma
(Tumor)
Original: Cytologic/ histologic/ and ultrastructural investigations#revealed#a dysgerminoma
#19235
middle Confidence
Subject:
histologic_investigation
(Detection Technology)
→
revealed
→
Object:
dysgerminoma
(Tumor)
Original: Cytologic/ histologic/ and ultrastructural investigations#revealed#a dysgerminoma
#19234
middle Confidence
Subject:
cytologic_investigation
(Detection Technology)
→
revealed
→
Object:
dysgerminoma
(Tumor)
Original: Cytologic/ histologic/ and ultrastructural investigations#revealed#a dysgerminoma
#19228
middle Confidence
Subject:
cytomorphologic_and_immunocytochemical_characteristics
(Diagnostic morphology and immune characteristics)
→
permit
→
Object:
preoperative_differentiation_of_MRT_from_other_malignant_tumors_of_childhood
(Diagnostic Process)
Original: Cytomorphologic and immunocytochemical characteristics#permit#preoperative differentiation of MRT from other malignant tumors of childhood
#19223
middle Confidence
Subject:
nuclear_PAX2_expression
(Protein expression)
→
correlated_with
→
Object:
prominent_nucleoli
(Protruding nucleoli)
Original: nuclear PAX2 expression#correlated with#nuclear atypia and prominent nucleoli
#19222
middle Confidence
Subject:
nuclear_PAX2_expression
(Protein expression)
→
correlated_with
→
Object:
nuclear_atypia
(Nuclear abnormalities)
Original: nuclear PAX2 expression#correlated with#nuclear atypia and prominent nucleoli
#19220
middle Confidence
Subject:
TOP2A
(DNA topoisomerase)
→
is_proliferation_marker_in
→
Object:
neoplastic_cells
(Tumor cells)
Original: Topoisomerase IIalpha#is#a strict proliferation marker in normal and neoplastic cells
#19219
middle Confidence
Subject:
TOP2A
(DNA topoisomerase)
→
is_proliferation_marker_in
→
Object:
normal_cells
(Normal cells)
Original: Topoisomerase IIalpha#is#a strict proliferation marker in normal and neoplastic cells
#19004
middle Confidence
Subject:
HMNA_positive_cells
(Cell phenotype)
→
were_significantly_higher_in
→
Object:
leukemic_patients
(Patient population)
Original: HMNA-positive cells#were significantly higher in#leukemic patients than non-leukemic individuals
#18938
middle Confidence
Subject:
cytological_feature
(Cytological characteristics)
→
is_statistically_significant_for
→
Object:
grading
(Tumor grade)
Original: six cytological features#were found to be#statistically significant for grading
#18899
middle Confidence
Subject:
AgNORs
(Nuclear structure markers)
→
serve_as
→
Object:
malignancy_biomarkers_in_colorectal_neoplasms
(Diagnostic biomarkers)
Original: AgNORs#serve as#malignancy biomarkers in colorectal neoplasms
#18874
middle Confidence
Subject:
AgNOR_number
(Number of nucleolar organizer region markers)
→
differs_significantly_between
→
Object:
PCNA_negative_nuclei
(Protein negative nuclei)
Original: AgNOR numbers/ perimeters/ and contour indices#differ significantly between#PCNA-positive and -negative nuclei in PA samples
#18873
middle Confidence
Subject:
AgNOR_number
(Number of nucleolar organizer region markers)
→
differs_significantly_between
→
Object:
PCNA_positive_nuclei
(Protein positive nuclei)
Original: AgNOR numbers/ perimeters/ and contour indices#differ significantly between#PCNA-positive and -negative nuclei in PA samples
#18860
middle Confidence
Subject:
PCNA
(Cell proliferation protein)
→
is_expressed_in
→
Object:
neoplastic_lesions
(Lesion type)
Original: PCNA/ AgNOR/ oncogenes/ and tumor suppressor gene p53#are expressed in#preneoplastic and neoplastic lesions of rat and human livers
#18859
middle Confidence
Subject:
PCNA
(Cell proliferation protein)
→
is_expressed_in
→
Object:
preneoplastic_lesions
(Lesion type)
Original: PCNA/ AgNOR/ oncogenes/ and tumor suppressor gene p53#are expressed in#preneoplastic and neoplastic lesions of rat and human livers
#18858
middle Confidence
Subject:
AgNOR_staining_of_exfoliated_cells
(Dyeing technology)
→
is_used_for
→
Object:
diagnostic_nasopharyngeal_cancer
(Disease diagnosis)
Original: AgNOR staining of exfoliated cells#is used for#diagnosing nasopharyngeal cancer
#18857
middle Confidence
Subject:
NOR_proteins
(Nucleolar Organizer Region Protein)
→
can_be_used_as
→
Object:
marker_of_transcription_level_in_malignant_tumors
(Molecular markers)
Original: NOR proteins#could be used as#a marker of ribosomal DNA and transcription level in malignant tumors
#18856
middle Confidence
Subject:
NOR_proteins
(Nucleolar Organizer Region Protein)
→
can_be_used_as
→
Object:
marker_of_ribosomal_DNA
(Molecular markers)
Original: NOR proteins#could be used as#a marker of ribosomal DNA and transcription level in malignant tumors
#18852
middle Confidence
Subject:
AgNORs
(Molecular markers)
→
are_used_for
→
Object:
assessing_proliferative_potential
(Cell proliferation ability)
Original: AgNORs#are used for#assessing proliferative potential of tumors
#18834
middle Confidence
Subject:
Ki-1_lymphoma
(Tumor)
→
characterized_by
→
Object:
immunologic_findings
(Immunological manifestations)
Original: Ki-1 lymphoma in children#is characterized by#clinical presentations/ and histologic and immunologic findings
#18833
middle Confidence
Subject:
Ki-1_lymphoma
(Tumor)
→
characterized_by
→
Object:
histologic_findings
(Histological manifestations)
Original: Ki-1 lymphoma in children#is characterized by#clinical presentations/ and histologic and immunologic findings
#18832
middle Confidence
Subject:
Ki-1_lymphoma
(Tumor)
→
characterized_by
→
Object:
clinical_presentations
(Clinical manifestations)
Original: Ki-1 lymphoma in children#is characterized by#clinical presentations/ and histologic and immunologic findings
#18826
middle Confidence
Subject:
Malignant_rhabdoid_tumor
(Tumor type)
→
is_characterized_by
→
Object:
invasive_proliferation_of_polygonal_to_ovoid_cells
(Cell morphology)
Original: Malignant rhabdoid tumor (MRT)#is characterized by#invasive proliferation of polygonal to ovoid cells
#18818
middle Confidence
Subject:
bone_marrow_biopsy
(Clinical operation)
→
demonstrates_infiltration_of
→
Object:
atypical_mast_cells
(Abnormal cells)
Original: Bone marrow biopsy#demonstrated infiltration of#atypical mast cells
#18817
middle Confidence
Subject:
Anorectal_melanoma
(Tumor)
→
presents_with
→
Object:
bleeding_per_rectum
(symptom)
Original: Anorectal melanoma#presents with#bleeding per rectum
#18816
middle Confidence
Subject:
Alpha-SMA_expression
(Protein expression)
→
is_observed_in
→
Object:
stroma_of_ameloblastic_carcinoma
(Interstitial cells)
Original: Alpha-SMA expression#is observed in#odontogenic epithelium and stroma of ameloblastic carcinoma
#18815
middle Confidence
Subject:
Alpha-SMA_expression
(Protein expression)
→
is_observed_in
→
Object:
odontogenic_epithelium_of_ameloblastic_carcinoma
(Epithelial cells)
Original: Alpha-SMA expression#is observed in#odontogenic epithelium and stroma of ameloblastic carcinoma
#18799
middle Confidence
Subject:
Myxomas_in_renal_pelvis
(Tumor type)
→
can_present_with
→
Object:
hydronephrosis
(Disease phenotype)
Original: Myxomas in the renal pelvis#can present with#hydronephrosis
#18797
middle Confidence
Subject:
a_62-year-old_female
(Patient characteristics)
→
was_diagnosed_with
→
Object:
gastric_gastrointestinal_stromal_tumor
(Gastrointestinal stromal tumors)
Original: A 62-year-old female#was diagnosed with#a huge gastric gastrointestinal stromal tumor (GIST)
#18795
middle Confidence
Subject:
alpha-fetoprotein_level
(Tumor markers)
→
is_upregulated_in
→
Object:
19-year-old_female_with_ascites_enlarged_liver_pelvic_masses
(Patient phenotype)
Original: A 19-year-old female#had#ascites/ an enlarged liver/ pelvic masses/ and an alpha-fetoprotein level of 397/000 micrograms/L with a normal beta-human chorionic gonadotropin serum level
#18794
middle Confidence
Subject:
cytologic_characteristics_identification
(Diagnostic techniques)
→
is_important_for
→
Object:
differential_diagnosis_of_LCNEC
(Diagnostic Process)
Original: correct identification of cytologic characteristics#is important for#differential diagnosis of LCNEC
#18792
middle Confidence
Subject:
neuron-specific_enolase
(Enzyme Protein)
→
is_produced_by
→
Object:
leiomyosarcoma
(Leiomyosarcoma)
Original: Neuron-specific enolase (NSE)#is produced by#leiomyosarcoma in the mesentery
#18790
middle Confidence
Subject:
Tumor
(Tumor tissue)
→
is_diagnosed_as
→
Object:
large_cell_neuroendocrine_carcinoma_of_colon
(Tumor type)
Original: Tumor#is diagnosed as#large cell neuroendocrine carcinoma of the colon
#18788
middle Confidence
Subject:
Triple-negative_apocrine_carcinoma
(Tumor type)
→
must_be_considered_in
→
Object:
differential_diagnoses_of_breast_lesions
(Diagnostic Process)
Original: Triple-negative apocrine carcinoma#must be considered in#differential diagnoses of breast lesions
#18787
middle Confidence
Subject:
diffuse_large_B-cell_lymphoma
(Tumor)
→
is_of
→
Object:
B-cell_type
(Cell Type)
Original: diagnosis#was#long-standing pyothorax-associated lymphoma (diffuse large-cell lymphoma/ B-cell type)
#18786
middle Confidence
Subject:
pyothorax-associated_lymphoma
(Tumor)
→
diagnosed_as
→
Object:
diffuse_large_B-cell_lymphoma
(Tumor)
Original: diagnosis#was#long-standing pyothorax-associated lymphoma (diffuse large-cell lymphoma/ B-cell type)
#18782
middle Confidence
Subject:
Pituitary_adenomas
(Benign tumors)
→
cause
→
Object:
difficulties_in_histological_diagnosis
(Difficulty in diagnosis)
Original: Pituitary adenomas#cause#significant difficulties in histological diagnosis
#18777
middle Confidence
Subject:
AMACR
(Enzymes)
→
is_commonly_positive
→
Object:
AMACR_positivity
(Immunohistochemical markers)
Original: PAX8 and AMACR#are commonly#positive
#18776
middle Confidence
Subject:
PAX8
(Transcription Factors)
→
is_commonly_positive
→
Object:
PAX8_positivity
(Immunohistochemical markers)
Original: PAX8 and AMACR#are commonly#positive
#18775
middle Confidence
Subject:
Accurate_diagnosis_of_LHS
(Diagnostic Process)
→
requires
→
Object:
classification_as_acinar
(Diagnostic criteria)
Original: Accurate diagnosis of LHS#requires#identification of pancreatic primary and classification as acinar
#18774
middle Confidence
Subject:
Accurate_diagnosis_of_LHS
(Diagnostic Process)
→
requires
→
Object:
identification_of_pancreatic_primary
(Diagnostic criteria)
Original: Accurate diagnosis of LHS#requires#identification of pancreatic primary and classification as acinar
#18734
middle Confidence
Subject:
large_irregular_cells
(Tumor cells)
→
stain_positive_with
→
Object:
BRAF(V600E)
(Oncogene mutant protein)
Original: Large/ irregularly shaped cells#stain positively with#Melan A/ HMB45/ S-100 protein/ SOX10/ CD10 (focally)/ and BRAF(V600E)
#18730
middle Confidence
Subject:
PEComas
(Tumor type)
→
are_differentially_diagnosed_with
→
Object:
melanoma
(Tumor type)
Original: PEComas#are differentially diagnosed with#gastrointestinal stromal tumors and metastases of carcinoma and melanoma
#18729
middle Confidence
Subject:
PEComas
(Tumor type)
→
are_differentially_diagnosed_with
→
Object:
carcinoma
(Tumor type)
Original: PEComas#are differentially diagnosed with#gastrointestinal stromal tumors and metastases of carcinoma and melanoma
#18728
middle Confidence
Subject:
PEComas
(Tumor type)
→
are_differentially_diagnosed_with
→
Object:
gastrointestinal_stromal_tumors
(Tumor type)
Original: PEComas#are differentially diagnosed with#gastrointestinal stromal tumors and metastases of carcinoma and melanoma
#18713
middle Confidence
Subject:
Epithelioid_cells
(Cell Type)
→
exhibit
→
Object:
marked_cytologic_atypia
(Cell phenotype)
Original: Epithelioid cells#exhibit#marked cytologic atypia
#18674
middle Confidence
Subject:
MYC
(Transcription Factors)
→
provides
→
Object:
proliferative_rate_estimation
(Diagnostic Process)
Original: Combination of PCNA/ c-myc p62/ and AgNORs#provides#an accurate estimate of proliferative rate in non-Hodgkin's lymphomas
#18673
middle Confidence
Subject:
PCNA
(DNA polymerase accessory factors)
→
provides
→
Object:
proliferative_rate_estimation
(Diagnostic Process)
Original: Combination of PCNA/ c-myc p62/ and AgNORs#provides#an accurate estimate of proliferative rate in non-Hodgkin's lymphomas
#18650
middle Confidence
Subject:
prominent_nucleoli
(Nucleolar morphology)
→
are_observed_in
→
Object:
prostatic_carcinoma
(Disease phenotype)
Original: Prominent nucleoli#are observed in#prostatic carcinoma and benign mimickers
#18642
middle Confidence
Subject:
Fine-needle_aspiration_cytology
(Diagnostic techniques)
→
correlates_with
→
Object:
histology_of_oncocytic_neoplasms
(Histological diagnosis)
Original: Fine-needle aspiration cytology#correlates with#histology of oncocytic neoplasms
#18635
middle Confidence
Subject:
ultrastructural_findings
(Ultrastructural characteristics)
→
characterize
→
Object:
filiform_large_cell_lymphoma_of_spleen
(Tumor diseases)
Original: Histological/ immunohistochemical/ and ultrastructural findings#characterize#a filiform large cell lymphoma of the spleen
#18634
middle Confidence
Subject:
immunohistochemical_findings
(Immunohistochemical characteristics)
→
characterize
→
Object:
filiform_large_cell_lymphoma_of_spleen
(Tumor diseases)
Original: Histological/ immunohistochemical/ and ultrastructural findings#characterize#a filiform large cell lymphoma of the spleen
#18633
middle Confidence
Subject:
histological_findings
(Histological characteristics)
→
characterize
→
Object:
filiform_large_cell_lymphoma_of_spleen
(Tumor diseases)
Original: Histological/ immunohistochemical/ and ultrastructural findings#characterize#a filiform large cell lymphoma of the spleen
#18627
middle Confidence
Subject:
Lesion
(Tumor lesions)
→
shows_positivity_for
→
Object:
vimentin
(Intermediate filament protein)
Original: Lesion#showed positivity for#vimentin
#18626
middle Confidence
Subject:
Immunocytochemical_tests
(Immunohistochemistry)
→
confirms
→
Object:
mesenchymal_nature_of_lesion
(Tumor tissue properties)
Original: Immunocytochemical tests#confirmed#mesenchymal nature of the lesion
#18622
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
h-caldesmon
(Cytoskeletal proteins)
Original: Tumor cells#were positive for#CD10 and negative for desmin and h-caldesmon
#18621
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
desmin
(Cytoskeletal proteins)
Original: Tumor cells#were positive for#CD10 and negative for desmin and h-caldesmon
#18620
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD10
(Cell surface markers)
Original: Tumor cells#were positive for#CD10 and negative for desmin and h-caldesmon
#18588
middle Confidence
Subject:
AgNOR_number_counting
(AgNOR Count)
→
differentiations
→
Object:
nevus_cells
(Benign mole cells)
Original: Counting AgNOR numbers#differentiates#small cell melanoma cells from nevus cells
#18587
middle Confidence
Subject:
AgNOR_number_counting
(AgNOR Count)
→
differentiations
→
Object:
small_cell_melanoma_cells
(Tumor cells)
Original: Counting AgNOR numbers#differentiates#small cell melanoma cells from nevus cells
#18527
middle Confidence
Subject:
NDP_kinase
(Kinase)
→
shows
→
Object:
strong_immunoreactivity
(Protein expression)
Original: NDP kinase#shows#strong immunoreactivity in 66% of invasive pancreatic duct cell carcinomas
#18526
middle Confidence
Subject:
interphase_NOR_numbers
(NOR)
→
correlates_with
→
Object:
tumor_grade
(Tumor grade)
Original: interphase NOR numbers#correlate with#tumor grade in NHL
#18502
middle Confidence
Subject:
malignant_breast_lesions
(Malignant breast lesions)
→
showed_higher_counts_than
→
Object:
benign_breast_disease
(Benign breast lesions)
Original: Malignant breast lesions#showed#higher counts than benign breast disease
#18498
middle Confidence
Subject:
splenic_enlargement
(Pathological characteristics)
→
is_characterized_by
→
Object:
red_pulp_expansion
(Histological changes)
Original: splenic enlargement#is characterized by#red pulp expansion due to lymphocytic infiltration
#18497
middle Confidence
Subject:
histopathology_of_spleen
(Detection Methods)
→
is_reviewed_for
→
Object:
T-cell_prolymphocytic_leukemia
(Hematologic malignancies)
Original: histopathology of spleen#is reviewed for#T-cell large granular lymphocyte leukemia and T-cell prolymphocytic leukemia
#18496
middle Confidence
Subject:
histopathology_of_spleen
(Detection Methods)
→
is_reviewed_for
→
Object:
T-cell_large_granular_lymphocyte_leukemia
(Hematologic malignancies)
Original: histopathology of spleen#is reviewed for#T-cell large granular lymphocyte leukemia and T-cell prolymphocytic leukemia
#18494
middle Confidence
Subject:
lesion
(Pathological characteristics)
→
shows
→
Object:
proliferation_of_spindle-shaped_cells
(Cell morphology)
Original: lesion#showed#proliferation of spindle-shaped cells with elongated nuclei arranged in interlaced fascicle pattern
#18493
middle Confidence
Subject:
intraosseous_rhabdomyosarcoma
(Tumor subtype)
→
has_predilection_for
→
Object:
gnathic_bones
(Anatomical location)
Original: intraosseous rhabdomyosarcoma#is#a rare aggressive subtype with predilection for gnathic bones
#18468
middle Confidence
Subject:
diagnostic_alternative_belief
(Probability of diagnosis)
→
was_shown_to_be
→
Object:
high
(Quantitative indicators)
Original: Belief for diagnostic alternatives#was shown to be#high using relative likelihood ratios
#18462
middle Confidence
Subject:
osteosarcoma
(disease)
→
was_determined_by
→
Object:
cytological_characteristics
(Cytological characteristics)
Original: osteosarcoma#was determined by#cytological characteristics
#18445
middle Confidence
Subject:
Diagnosis
(Diagnostic Process)
→
is_established_by
→
Object:
immunohistochemical_criteria
(Immunohistochemistry standards)
Original: Definitive diagnosis#is established by#characteristic histological and immunohistochemical criteria
#18444
middle Confidence
Subject:
Diagnosis
(Diagnostic Process)
→
is_established_by
→
Object:
histological_criteria
(Histological criteria)
Original: Definitive diagnosis#is established by#characteristic histological and immunohistochemical criteria
#18438
middle Confidence
Subject:
Histologic_features
(Histological characteristics)
→
distinguish
→
Object:
squamous_cell_carcinoma
(Disease Type)
Original: Histologic features#distinguish#epithelioid trophoblastic tumor from squamous cell carcinoma
#18437
middle Confidence
Subject:
Histologic_features
(Histological characteristics)
→
distinguish
→
Object:
epithelioid_trophoblastic_tumor
(Disease Type)
Original: Histologic features#distinguish#epithelioid trophoblastic tumor from squamous cell carcinoma
#18425
middle Confidence
Subject:
diagnosis_of_rare_entity
(Diagnostic Process)
→
was_confirmed_by
→
Object:
histopathological_examination
(Diagnostic Methods)
Original: diagnosis of rare entity#was confirmed by#histopathological examination of resected tumors
#18416
middle Confidence
Subject:
Immunomarkers
(Biomarkers)
→
are_useful_for
→
Object:
adenocarcinoma
(Tumor)
Original: Relatively new and specific immunomarkers#are useful for#mesothelioma vs. adenocarcinoma
#18415
middle Confidence
Subject:
Immunomarkers
(Biomarkers)
→
are_useful_for
→
Object:
mesothelioma
(Tumor)
Original: Relatively new and specific immunomarkers#are useful for#mesothelioma vs. adenocarcinoma
#18384
middle Confidence
Subject:
tumors
(Tumor)
→
were_diagnosed_as
→
Object:
metastatic_HAC
(Disease phenotype)
Original: tumors#were diagnosed as#HAC and metastatic HAC
#18383
middle Confidence
Subject:
tumors
(Tumor)
→
were_diagnosed_as
→
Object:
HAC
(Disease phenotype)
Original: tumors#were diagnosed as#HAC and metastatic HAC
#18353
middle Confidence
Subject:
ultrastructural_and_immunocytochemical_studies
(Morphological detection method)
→
support
→
Object:
diagnosis_of_malignant_melanoma
(Disease diagnosis conclusion)
Original: Ultrastructural and immunocytochemical studies#support#diagnosis of malignant melanoma
#18349
middle Confidence
Subject:
large_nuclear_size
(Nuclear morphology)
→
is_diagnostic_marker_for
→
Object:
carcinoma_cells
(Tumor cells)
Original: features with high specificity and PPV#included#irregular nuclear contours and large nuclear size
#18348
middle Confidence
Subject:
irregular_nuclear_contours
(Nuclear morphology)
→
is_diagnostic_marker_for
→
Object:
carcinoma_cells
(Tumor cells)
Original: features with high specificity and PPV#included#irregular nuclear contours and large nuclear size
#18328
middle Confidence
Subject:
Cytologic_features_of_MS
(Cytological characteristics)
→
identified_on
→
Object:
Pap_smear_using_ThinPrep
(Cytological detection technology)
Original: Cytologic features of MS#identified and reported#on Pap smears using ThinPrep method
#18319
middle Confidence
Subject:
Barrett's Esophagus (BE)
(disease)
→
is_recognized_by
→
Object:
columnar_cells
(Cell Type)
Original: BE#is recognized by#the presence of goblet cells within clusters of uniform columnar cells with vesicular nuclei
#18311
middle Confidence
Subject:
fine_needle_aspiration_cytology
(Cytological testing methods)
→
is_used_in
→
Object:
pseudolymphoma_cutis
(disease)
Original: fine needle aspiration cytology#is used in#pseudolymphoma cutis
#18310
middle Confidence
Subject:
MTSC
(Tumor subtype)
→
is_similar_to
→
Object:
PRCC
(Tumor subtype)
Original: MTSC#is similar to#sPRCC
#18309
middle Confidence
Subject:
MTSC
(Tumor subtype)
→
is_similar_to
→
Object:
sPRCC
(Tumor subtype)
Original: MTSC#is similar to#sPRCC
#18302
middle Confidence
Subject:
Early_gastric_cancer
(Tumor type)
→
is_predominantly
→
Object:
type_IIc_(depressed)_macroscopically
(Naked eye morphology)
Original: 30 tub 0 EGCs#were predominantly#type IIc (depressed) macroscopically
#18301
middle Confidence
Subject:
Lesions
(Tumor lesions)
→
resemble
→
Object:
gastric_adenoma_with_severe_atypism
(Adenomatous lesions)
Original: Lesions#resembled#gastric adenoma with severe atypism
#18298
middle Confidence
Subject:
Tubular_adenocarcinoma
(Tumor type)
→
is_characterized_by
→
Object:
very_well_differentiation
(Differentiation state)
Original: Tubular adenocarcinoma#is characterized by#very well differentiation
#18296
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
does_not_express
→
Object:
CD8
(cell marker molecules)
Original: Tumor cells#did not express#cytokeratin/ CD20/ CD79A/ CD4/ CD8
#18295
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
does_not_express
→
Object:
CD4
(cell marker molecules)
Original: Tumor cells#did not express#cytokeratin/ CD20/ CD79A/ CD4/ CD8
#18294
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
does_not_express
→
Object:
CD79A
(B cell marker molecules)
Original: Tumor cells#did not express#cytokeratin/ CD20/ CD79A/ CD4/ CD8
#18293
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
does_not_express
→
Object:
CD20
(B cell marker molecules)
Original: Tumor cells#did not express#cytokeratin/ CD20/ CD79A/ CD4/ CD8
#18292
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
does_not_express
→
Object:
cytokeratin
(Cytokeratin)
Original: Tumor cells#did not express#cytokeratin/ CD20/ CD79A/ CD4/ CD8
#18291
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
expresses
→
Object:
cytotoxic_protein
(Cytotoxic proteins)
Original: Tumor cells#expressed#CD3/ cytotoxic protein/ and EBER
#18281
middle Confidence
Subject:
Multiple_thyroid_nodules
(Pathological entity)
→
include
→
Object:
hypoechoic_solid_irregularly_shaped_nodule
(Nodule morphology)
Original: Multiple thyroid nodules#included#a 1.5 cm hypoechoic/ solid/ irregularly-shaped nodule
#18276
middle Confidence
Subject:
tumor
(Tumor type)
→
shows
→
Object:
desmin
(protein)
Original: tumor cells#showed#positive staining for myoglobin and desmin
#18275
middle Confidence
Subject:
tumor
(Tumor type)
→
shows
→
Object:
myoglobin
(protein)
Original: tumor cells#showed#positive staining for myoglobin and desmin
#18243
middle Confidence
Subject:
PAC
(disease)
→
has
→
Object:
relatively_constant_cytological_features
(Cytological characteristics)
Original: PAC#has#relatively constant cytological features
#18237
middle Confidence
Subject:
absence_of_mono_or_plurivacuolated_lipoblasts
(Cell morphology)
→
makes_impossible
→
Object:
differential_diagnosis_between_pleomorphic_histiocytoma_and_liposarcoma
(Diagnostic Process)
Original: Differential diagnosis between pleomorphic histiocytoma and liposarcoma#is impossible when#mono or plurivacuolated lipoblasts are absent
#18236
middle Confidence
Subject:
cytomorphologic_findings
(Cell morphological characteristics)
→
are_described_in
→
Object:
tumor_diagnosis
(Tumor Diagnosis Process)
Original: Cytomorphologic findings#are described in#tumor diagnosis
#18235
middle Confidence
Subject:
patients
(patient)
→
presented_with
→
Object:
hormone-related_symptoms
(symptom)
Original: Most patients#presented with#hormone-related symptoms for a mean of 6.8 months
#18234
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are
→
Object:
vimentin_positive_with_prominent_nucleoli
(Protein expression status)
Original: Tumor cells#were#vimentin positive with prominent nucleoli
#18226
middle Confidence
Subject:
case
(Case)
→
need_to_be_confirmed_by
→
Object:
Immunohistochemistry
(Diagnostic techniques)
Original: Such cases#need to be confirmed by#histopathology and immunohistochemistry
#18225
middle Confidence
Subject:
case
(Case)
→
need_to_be_confirmed_by
→
Object:
histopathology
(Diagnostic techniques)
Original: Such cases#need to be confirmed by#histopathology and immunohistochemistry
#18205
middle Confidence
Subject:
lymph_node_biopsy
(Clinical testing)
→
identified
→
Object:
lymphocytes
(Immune cells)
Original: lymph node biopsy#confirmed#mantle cell lymphoma
#18191
middle Confidence
Subject:
Epithelial_proliferation
(Cytological morphological characteristics)
→
are_useful_for
→
Object:
grading_oral_epithelial_dysplasia
(Disease classification)
Original: Normal and abnormal superficial mitotic figures and endophytic epithelial proliferation#are useful for#grading oral epithelial dysplasia
#18190
middle Confidence
Subject:
Mitotic_figures
(Cytological morphological characteristics)
→
are_useful_for
→
Object:
grading_oral_epithelial_dysplasia
(Disease classification)
Original: Normal and abnormal superficial mitotic figures and endophytic epithelial proliferation#are useful for#grading oral epithelial dysplasia
#18184
middle Confidence
Subject:
triple_negative_group
(Clinical Grouping)
→
shows_preferential_staining_for
→
Object:
c-kit
(Receptor tyrosine kinases)
Original: triple-negative group#showed preferential staining for#CK5/6/ CK14/ EGFR/ c-kit
#18183
middle Confidence
Subject:
triple_negative_group
(Clinical Grouping)
→
shows_preferential_staining_for
→
Object:
EGFR
(Receptor tyrosine kinases)
Original: triple-negative group#showed preferential staining for#CK5/6/ CK14/ EGFR/ c-kit
#18182
middle Confidence
Subject:
triple_negative_group
(Clinical Grouping)
→
shows_preferential_staining_for
→
Object:
CK14
(Cytoskeletal proteins)
Original: triple-negative group#showed preferential staining for#CK5/6/ CK14/ EGFR/ c-kit
#18181
middle Confidence
Subject:
triple_negative_group
(Clinical Grouping)
→
shows_preferential_staining_for
→
Object:
CK5/6
(Cytoskeletal proteins)
Original: triple-negative group#showed preferential staining for#CK5/6/ CK14/ EGFR/ c-kit
#18174
middle Confidence
Subject:
cervical_scraping_smears
(Test samples)
→
were_reviewed_from
→
Object:
adenoma_malignum_of_uterine_cervix
(disease)
Original: Cervical scraping smears#were reviewed from#cases of histologically confirmed adenoma malignum of the uterine cervix
#18168
middle Confidence
Subject:
distinct_morphological_features
(Histopathological features)
→
enable
→
Object:
preoperative_diagnosis_of_spermatocytic_seminoma
(diagnosis)
Original: distinct morphological features#enable#preoperative diagnosis of spermatocytic seminoma
#18167
middle Confidence
Subject:
absence_of_lymphocytes
(Histopathological features)
→
is_helpful_in
→
Object:
diagnosis_of_spermatocytic_seminoma
(diagnosis)
Original: absence of lymphocytes#is helpful in#diagnosis of spermatocytic seminoma
#18166
middle Confidence
Subject:
low_mitotic_rate
(Histopathological features)
→
is_helpful_in
→
Object:
diagnosis_of_spermatocytic_seminoma
(diagnosis)
Original: low mitotic rate#is helpful in#diagnosis of spermatocytic seminoma
#18150
middle Confidence
Subject:
radiologic_findings
(Imaging features)
→
has_adjunctive_role_in
→
Object:
HCC
(Tumor type)
Original: The cytologic features of fine needle aspiration biopsies from well- and poorly differentiated HCC#were reviewed and#the adjunctive role of serum AFP/ HBV markers and radiologic findings evaluated
#18148
middle Confidence
Subject:
Melanoma_cells
(Tumor cells)
→
contained
→
Object:
large_lightly_staining_nuclei
(Nuclear morphology)
Original: Melanoma cells#contained#large/ lightly staining nuclei and prominent nucleoli
#18147
middle Confidence
Subject:
Melanoma_cells
(Tumor cells)
→
appeared
→
Object:
round_or_polygonal
(Cell morphology)
Original: Melanoma cells#appeared#round or polygonal
#18146
middle Confidence
Subject:
Epithelium
(Epithelial cells)
→
has
→
Object:
enlarged_nuclei
(Nuclear morphology)
Original: Epithelium#has#enlarged nuclei and intermediate to large nucleoli
#18145
middle Confidence
Subject:
Enhancement_of_septa
(Imaging signs)
→
should_reveal
→
Object:
malignancy
(Malignant tumors)
Original: Enhancement of septa#should reveal#malignancy
#18111
middle Confidence
Subject:
nuclear_enlargement
(Nuclear morphology)
→
is_helpful_for
→
Object:
diagnostics limited adenocarcinoma
(Diagnostic Process)
Original: nuclear enlargement#is helpful for#diagnosing limited adenocarcinoma
#18109
middle Confidence
Subject:
mitotic_count>2/HPF
(Cell proliferation markers)
→
distinguishes
→
Object:
TC
(Disease Type)
Original: Overall mean number of mitoses >2/HPF#distinguishes#AC from TC
#18108
middle Confidence
Subject:
mitotic_count>2/HPF
(Cell proliferation markers)
→
distinguishes
→
Object:
AC
(Disease Type)
Original: Overall mean number of mitoses >2/HPF#distinguishes#AC from TC
#18107
middle Confidence
Subject:
comedo-like_necrosis
(Tissue morphology)
→
distinguishes
→
Object:
TC
(Disease Type)
Original: Comedo-like necrosis#distinguishes#AC from TC
#18106
middle Confidence
Subject:
comedo-like_necrosis
(Tissue morphology)
→
distinguishes
→
Object:
AC
(Disease Type)
Original: Comedo-like necrosis#distinguishes#AC from TC
#18103
middle Confidence
Subject:
tumors
(Tumor)
→
have
→
Object:
single_cell_growth_patterns
(Tumor growth pattern)
Original: tumors#have#epithelioid cells with prominent nucleoli and cribriform/ solid/ or infiltrating single-cell growth patterns
#18102
middle Confidence
Subject:
tumors
(Tumor)
→
have
→
Object:
epithelioid_cells_with_prominent_nucleoli
(Tumor cell morphology)
Original: tumors#have#epithelioid cells with prominent nucleoli and cribriform/ solid/ or infiltrating single-cell growth patterns
#18099
middle Confidence
Subject:
123C3
(Monoclonal antibody markers)
→
is_useful_marker_for
→
Object:
gastric_small_cell_carcinoma
(Tumor)
Original: Leu-7 and 123C3 monoclonal antibodies#are useful markers for#gastric small cell carcinoma
#18098
middle Confidence
Subject:
Leu-7
(Monoclonal antibody markers)
→
is_useful_marker_for
→
Object:
gastric_small_cell_carcinoma
(Tumor)
Original: Leu-7 and 123C3 monoclonal antibodies#are useful markers for#gastric small cell carcinoma
#18097
middle Confidence
Subject:
123C3
(Monoclonal antibody markers)
→
is_positive_marker_for
→
Object:
neoplastic_cells
(Tumor cells)
Original: Neoplastic cells#were positive for#Leu-7 (CD57) and 123C3 (CD56/ NCAM) on the surface membrane
#18096
middle Confidence
Subject:
Leu-7
(Monoclonal antibody markers)
→
is_positive_marker_for
→
Object:
neoplastic_cells
(Tumor cells)
Original: Neoplastic cells#were positive for#Leu-7 (CD57) and 123C3 (CD56/ NCAM) on the surface membrane
#18065
middle Confidence
Subject:
Screening_technique
(Diagnostic techniques)
→
identified
→
Object:
malignant_lesions
(Disease phenotype)
Original: Screening technique#identified#all malignant lesions
#18058
middle Confidence
Subject:
Malignant_cells
(Tumor cells)
→
are_characterized_by
→
Object:
prominent_nucleoli
(Nuclear characteristics)
Original: Malignant cells#are characterized by#clear cytoplasm/ vesicular nuclei/ and prominent nucleoli
#18057
middle Confidence
Subject:
Malignant_cells
(Tumor cells)
→
are_characterized_by
→
Object:
vesicular_nuclei
(Nuclear characteristics)
Original: Malignant cells#are characterized by#clear cytoplasm/ vesicular nuclei/ and prominent nucleoli
#18056
middle Confidence
Subject:
Malignant_cells
(Tumor cells)
→
are_characterized_by
→
Object:
clear_cytoplasm
(Cell morphology)
Original: Malignant cells#are characterized by#clear cytoplasm/ vesicular nuclei/ and prominent nucleoli
#18055
middle Confidence
Subject:
RDD_histiocytes
(Histiocytes)
→
are_characterized_by
→
Object:
voluminous_cytoplasm_with_engulfment_of_inflammatory_cells
(Cell morphology)
Original: RDD histiocytes#are characterized by#enlarged round to oval nuclei/ distinct nucleoli/ and voluminous cytoplasm with engulfment of inflammatory cells
#18054
middle Confidence
Subject:
RDD_histiocytes
(Histiocytes)
→
are_characterized_by
→
Object:
distinct_nucleoli
(Nuclear characteristics)
Original: RDD histiocytes#are characterized by#enlarged round to oval nuclei/ distinct nucleoli/ and voluminous cytoplasm with engulfment of inflammatory cells
#18053
middle Confidence
Subject:
RDD_histiocytes
(Histiocytes)
→
are_characterized_by
→
Object:
enlarged_round_to_oval_nuclei
(Nuclear characteristics)
Original: RDD histiocytes#are characterized by#enlarged round to oval nuclei/ distinct nucleoli/ and voluminous cytoplasm with engulfment of inflammatory cells
#18052
middle Confidence
Subject:
Large_atypical_lymphocytes
(Tumor cells)
→
are_characterized_by
→
Object:
prominent_nucleoli
(Nuclear characteristics)
Original: Large atypical lymphocytes#are characterized by#bizarre/ multilobulated nuclei with coarse chromatin and prominent nucleoli
#18051
middle Confidence
Subject:
Large_atypical_lymphocytes
(Tumor cells)
→
are_characterized_by
→
Object:
bizarre_multilobulated_nuclei_with_coarse_chromatin
(Nuclear characteristics)
Original: Large atypical lymphocytes#are characterized by#bizarre/ multilobulated nuclei with coarse chromatin and prominent nucleoli
#18050
middle Confidence
Subject:
Medium_to_large_cells
(Tumor cells)
→
are_characterized_by
→
Object:
many_mitotic_figures
(Cell proliferation characteristics)
Original: Medium to large cells#are characterized by#scanty cytoplasm/ irregular nuclear margins/ prominent nucleoli/ and many mitotic figures
#18049
middle Confidence
Subject:
Medium_to_large_cells
(Tumor cells)
→
are_characterized_by
→
Object:
prominent_nucleoli
(Nuclear characteristics)
Original: Medium to large cells#are characterized by#scanty cytoplasm/ irregular nuclear margins/ prominent nucleoli/ and many mitotic figures
#18048
middle Confidence
Subject:
Medium_to_large_cells
(Tumor cells)
→
are_characterized_by
→
Object:
irregular_nuclear_margins
(Nuclear characteristics)
Original: Medium to large cells#are characterized by#scanty cytoplasm/ irregular nuclear margins/ prominent nucleoli/ and many mitotic figures
#18047
middle Confidence
Subject:
Medium_to_large_cells
(Tumor cells)
→
are_characterized_by
→
Object:
scanty_cytoplasm
(Cell morphology)
Original: Medium to large cells#are characterized by#scanty cytoplasm/ irregular nuclear margins/ prominent nucleoli/ and many mitotic figures
#18046
middle Confidence
Subject:
Reed-Sternberg_cells
(Tumor cells)
→
are_characterized_by
→
Object:
distinct_nucleoli
(Nuclear characteristics)
Original: Hodgkin cells#are characterized by#abundant/ clear/ vacuolated cytoplasm/ pleomorphic/ ovoid nuclei with thick nuclear membranes and distinct nucleoli
#18045
middle Confidence
Subject:
Reed-Sternberg_cells
(Tumor cells)
→
are_characterized_by
→
Object:
pleomorphic_ovoid_nuclei_with_thick_membranes
(Nuclear characteristics)
Original: Hodgkin cells#are characterized by#abundant/ clear/ vacuolated cytoplasm/ pleomorphic/ ovoid nuclei with thick nuclear membranes and distinct nucleoli
#18044
middle Confidence
Subject:
Reed-Sternberg_cells
(Tumor cells)
→
are_characterized_by
→
Object:
abundant_clear_vacuolated_cytoplasm
(Cell morphology)
Original: Hodgkin cells#are characterized by#abundant/ clear/ vacuolated cytoplasm/ pleomorphic/ ovoid nuclei with thick nuclear membranes and distinct nucleoli
#18043
middle Confidence
Subject:
Hodgkin_cells
(Tumor cells)
→
are_characterized_by
→
Object:
distinct_nucleoli
(Nuclear characteristics)
Original: Hodgkin cells#are characterized by#abundant/ clear/ vacuolated cytoplasm/ pleomorphic/ ovoid nuclei with thick nuclear membranes and distinct nucleoli
#18042
middle Confidence
Subject:
Hodgkin_cells
(Tumor cells)
→
are_characterized_by
→
Object:
pleomorphic_ovoid_nuclei_with_thick_membranes
(Nuclear characteristics)
Original: Hodgkin cells#are characterized by#abundant/ clear/ vacuolated cytoplasm/ pleomorphic/ ovoid nuclei with thick nuclear membranes and distinct nucleoli
#18041
middle Confidence
Subject:
Hodgkin_cells
(Tumor cells)
→
are_characterized_by
→
Object:
abundant_clear_vacuolated_cytoplasm
(Cell morphology)
Original: Hodgkin cells#are characterized by#abundant/ clear/ vacuolated cytoplasm/ pleomorphic/ ovoid nuclei with thick nuclear membranes and distinct nucleoli
#18040
middle Confidence
Subject:
High-grade lesions
(Pathological changes)
→
are_characterized_by
→
Object:
villiform_architecture
(Organizational structure characteristics)
Original: high-grade lesions#are characterized by#crowded/ irregular glandular architecture/ eosinophilic and oncocytic cytoplasm/ prominent nucleoli/ mild nuclear pleomorphism/ and villiform architecture
#18039
middle Confidence
Subject:
High-grade lesions
(Pathological changes)
→
are_characterized_by
→
Object:
mild_nuclear_pleomorphism
(Nuclear atypia)
Original: high-grade lesions#are characterized by#crowded/ irregular glandular architecture/ eosinophilic and oncocytic cytoplasm/ prominent nucleoli/ mild nuclear pleomorphism/ and villiform architecture
#18038
middle Confidence
Subject:
High-grade lesions
(Pathological changes)
→
are_characterized_by
→
Object:
prominent_nucleoli
(Nuclear characteristics)
Original: high-grade lesions#are characterized by#crowded/ irregular glandular architecture/ eosinophilic and oncocytic cytoplasm/ prominent nucleoli/ mild nuclear pleomorphism/ and villiform architecture
#18037
middle Confidence
Subject:
High-grade lesions
(Pathological changes)
→
are_characterized_by
→
Object:
oncocytic_cytoplasm
(Cell morphology)
Original: high-grade lesions#are characterized by#crowded/ irregular glandular architecture/ eosinophilic and oncocytic cytoplasm/ prominent nucleoli/ mild nuclear pleomorphism/ and villiform architecture
#18036
middle Confidence
Subject:
High-grade lesions
(Pathological changes)
→
are_characterized_by
→
Object:
eosinophilic_cytoplasm
(Cell morphology)
Original: high-grade lesions#are characterized by#crowded/ irregular glandular architecture/ eosinophilic and oncocytic cytoplasm/ prominent nucleoli/ mild nuclear pleomorphism/ and villiform architecture
#18035
middle Confidence
Subject:
High-grade lesions
(Pathological changes)
→
are_characterized_by
→
Object:
crowded_irregular_glandular_architecture
(Organizational structure characteristics)
Original: high-grade lesions#are characterized by#crowded/ irregular glandular architecture/ eosinophilic and oncocytic cytoplasm/ prominent nucleoli/ mild nuclear pleomorphism/ and villiform architecture
#18015
middle Confidence
Subject:
Low-grade_PTC
(Tumor type)
→
was_identified_with
→
Object:
fine_chromatin_pattern_in_cytology
(Cytological characteristics)
Original: Low-grade PTC and neoplastic non-PTC lesions#were identified with#a fine chromatin pattern in cytology specimens
#18007
middle Confidence
Subject:
adenocarcinoma
(Tumor type)
→
characterized_by
→
Object:
prominent_nucleoli
(Nuclear characteristics)
Original: adenocarcinoma#is characterized by#loss of cohesiveness/ nuclear overlap/ anisonucleosis/ irregular nuclear contours/ and prominent nucleoli
#18006
middle Confidence
Subject:
adenocarcinoma
(Tumor type)
→
characterized_by
→
Object:
irregular_nuclear_contours
(Nuclear characteristics)
Original: adenocarcinoma#is characterized by#loss of cohesiveness/ nuclear overlap/ anisonucleosis/ irregular nuclear contours/ and prominent nucleoli
#18005
middle Confidence
Subject:
adenocarcinoma
(Tumor type)
→
characterized_by
→
Object:
anisonucleosis
(Nuclear characteristics)
Original: adenocarcinoma#is characterized by#loss of cohesiveness/ nuclear overlap/ anisonucleosis/ irregular nuclear contours/ and prominent nucleoli
#18004
middle Confidence
Subject:
adenocarcinoma
(Tumor type)
→
characterized_by
→
Object:
nuclear_overlap
(Nuclear characteristics)
Original: adenocarcinoma#is characterized by#loss of cohesiveness/ nuclear overlap/ anisonucleosis/ irregular nuclear contours/ and prominent nucleoli
#18003
middle Confidence
Subject:
adenocarcinoma
(Tumor type)
→
characterized_by
→
Object:
loss_of_cohesiveness
(Cell behavior characteristics)
Original: adenocarcinoma#is characterized by#loss of cohesiveness/ nuclear overlap/ anisonucleosis/ irregular nuclear contours/ and prominent nucleoli
#17998
middle Confidence
Subject:
Optic_chiasm_biopsy
(Biopsy sample)
→
revealed
→
Object:
atypical_cells
(Atypical cells)
Original: Optic chiasm biopsy#revealed#a moderately cellular neoplasm with atypical/ discohesive cells
#17997
middle Confidence
Subject:
Optic_chiasm_biopsy
(Biopsy sample)
→
revealed
→
Object:
moderately_cellular_neoplasm
(Medium cellular tumor)
Original: Optic chiasm biopsy#revealed#a moderately cellular neoplasm with atypical/ discohesive cells
#17996
middle Confidence
Subject:
Myoepithelial_cells
(Myoepithelial cells)
→
helps_to_exclude
→
Object:
malignancy
(Malignant tumors)
Original: Fine nuclear chromatin with inconspicuous nucleoli and myoepithelial cells#helped to exclude#malignancy
#17995
middle Confidence
Subject:
Fine_nuclear_chromatin
(Nuclear chromatin)
→
helps_to_exclude
→
Object:
malignancy
(Malignant tumors)
Original: Fine nuclear chromatin with inconspicuous nucleoli and myoepithelial cells#helped to exclude#malignancy
#17949
middle Confidence
Subject:
Cells
(Cell Type)
→
are_positive_for
→
Object:
D2-40
(protein)
Original: Cells#are positive for#calretinin/ EMA/ cytokeratinAE1/AE3/ WT-1/ D2-40
#17948
middle Confidence
Subject:
Cells
(Cell Type)
→
are_positive_for
→
Object:
WT-1
(protein)
Original: Cells#are positive for#calretinin/ EMA/ cytokeratinAE1/AE3/ WT-1/ D2-40
#17947
middle Confidence
Subject:
Cells
(Cell Type)
→
are_positive_for
→
Object:
cytokeratin_AE1/AE3
(protein)
Original: Cells#are positive for#calretinin/ EMA/ cytokeratinAE1/AE3/ WT-1/ D2-40
#17946
middle Confidence
Subject:
Cells
(Cell Type)
→
are_positive_for
→
Object:
EMA
(protein)
Original: Cells#are positive for#calretinin/ EMA/ cytokeratinAE1/AE3/ WT-1/ D2-40
#17945
middle Confidence
Subject:
Cells
(Cell Type)
→
are_positive_for
→
Object:
calretinin
(protein)
Original: Cells#are positive for#calretinin/ EMA/ cytokeratinAE1/AE3/ WT-1/ D2-40
#17933
middle Confidence
Subject:
fine_needle_aspiration_of_thyroid
(Clinical operation)
→
yielded
→
Object:
papillary_fronds_of_carcinoma_cells
(Cell Type)
Original: Fine needle aspiration of thyroid#yielded#papillary fronds of carcinoma cells
#17932
middle Confidence
Subject:
abdominal_ultrasonography
(Imaging tests)
→
revealed
→
Object:
soft_tissue_mass_between_liver_and_kidney
(Disease phenotype)
Original: Abdominal ultrasonography#revealed#urinary calculi and a soft tissue mass between the liver and kidney
#17931
middle Confidence
Subject:
abdominal_ultrasonography
(Imaging tests)
→
revealed
→
Object:
urinary_calculi
(Disease phenotype)
Original: Abdominal ultrasonography#revealed#urinary calculi and a soft tissue mass between the liver and kidney
#17925
middle Confidence
Subject:
hepatosplenic_gamma-delta_T-cell_lymphoma
(Malignant lymphoma)
→
was_studied_with
→
Object:
immunohistochemical_staining
(Immunohistochemistry)
Original: A case of hepatosplenic gamma-delta T-cell lymphoma#was studied with#conventional histopathological and immunohistochemical staining
#17924
middle Confidence
Subject:
hepatosplenic_gamma-delta_T-cell_lymphoma
(Malignant lymphoma)
→
was_studied_with
→
Object:
conventional_histopathological_staining
(Pathological testing methods)
Original: A case of hepatosplenic gamma-delta T-cell lymphoma#was studied with#conventional histopathological and immunohistochemical staining
#17874
middle Confidence
Subject:
Hypereosinophilia
(Hematological manifestations)
→
is_associated_with
→
Object:
T_cell_lymphoma
(Tumor type)
Original: Hypereosinophilia#is associated with#T-cell lymphoma
#17857
middle Confidence
Subject:
histologic_examination
(Pathological technology)
→
indicates
→
Object:
dense_proliferation_of_similar_sized_atypical_cells_with_nucleoli_and_irregular_nuclear_border
(Cell morphology)
Original: Histologic examination#indicated#dense proliferation of similar-sized atypical cells with nucleoli and an irregular nuclear border
#17846
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
neural_markers
(Protein markers)
Original: Tumor cells#are negative for#epithelial/ smooth muscle/ and neural markers
#17845
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
smooth_muscle_markers
(Protein markers)
Original: Tumor cells#are negative for#epithelial/ smooth muscle/ and neural markers
#17844
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
epithelial_markers
(Protein markers)
Original: Tumor cells#are negative for#epithelial/ smooth muscle/ and neural markers
#17842
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
display
→
Object:
centrally_located_giant_nucleoli
(Nuclear structure)
Original: Tumor cells#display#centrally located giant nucleoli
#17838
middle Confidence
Subject:
neoplastic_glands
(Tumor gland)
→
reacts_with
→
Object:
carcinoembryonic_antigen
(Tumor markers)
Original: neoplastic glands#reacted strongly with#antimitochondria antibody/ carcinoembryonic antigen/ cytokeratin 20/ p53/ CDX2
#17829
middle Confidence
Subject:
metastatic_melanoma
(Tumor type)
→
can_present_in
→
Object:
urine_cytology
(Diagnostic testing)
Original: metastatic melanoma#can present in#urine cytology in patients with cystoprostatectomy followed by an ileal conduit
#17824
middle Confidence
Subject:
FNA
(Diagnostic techniques)
→
diagnoses
→
Object:
suspicious_for_malignancy
(Malignant tumors)
Original: 186 FNAs#were diagnosed as#atypical or suspicious for malignancy
#17823
middle Confidence
Subject:
FNA
(Diagnostic techniques)
→
diagnoses
→
Object:
atypical_cells
(Tumor cells)
Original: 186 FNAs#were diagnosed as#atypical or suspicious for malignancy
#17811
middle Confidence
Subject:
histopathological_features
(Histological characteristics)
→
raise_concern_for
→
Object:
deep_angiomyxoma
(disease)
Original: Histopathological features#raised concern for#deep angiomyxoma
#17810
middle Confidence
Subject:
cytologic_appearance_of_cells
(Cell morphology)
→
is_presented_in
→
Object:
fine_needle_aspiration_biopsies_of_renal_oncocytoma
(Histological sampling)
Original: Cytologic appearance of cells#is presented in#fine needle aspiration biopsies of renal oncocytoma
#17808
middle Confidence
Subject:
immunohistochemical_study
(Detection Methods)
→
was_performed_on
→
Object:
uterine_cervical_tumors
(Tumor tissue)
Original: Immunohistochemical study#was performed on#uterine cervical tumors
#17792
middle Confidence
Subject:
extraskeletal_osteosarcoma
(Tumor)
→
is
→
Object:
rare_malignant_soft_tissue_tumor
(Tumor type)
Original: extraskeletal osteosarcoma#is#a rare malignant soft tissue tumor
#17785
middle Confidence
Subject:
fine-needle_aspiration_cytology
(Detection Technology)
→
is_performed_on
→
Object:
intranodal_palisaded_myofibroblastoma
(Tumor type)
Original: fine-needle aspiration cytology#was performed on#intranodal palisaded myofibroblastoma
#17783
middle Confidence
Subject:
melanotic_schwannoma
(Tumor type)
→
occurs_in
→
Object:
paraspinal_region
(Anatomical location)
Original: melanotic schwannoma#most commonly occurs in#paraspinal region
#17776
middle Confidence
Subject:
lung_metastases
(Tumor tissue)
→
was_positive_for
→
Object:
vimentin
(Protein markers)
Original: The primary tumor and the lung metastases#were positive for#von Willebrand factor and vimentin
#17775
middle Confidence
Subject:
lung_metastases
(Tumor tissue)
→
was_positive_for
→
Object:
von_Willebrand_factor
(Protein markers)
Original: The primary tumor and the lung metastases#were positive for#von Willebrand factor and vimentin
#17774
middle Confidence
Subject:
primary_tumor
(Tumor tissue)
→
was_positive_for
→
Object:
vimentin
(Protein markers)
Original: The primary tumor and the lung metastases#were positive for#von Willebrand factor and vimentin
#17773
middle Confidence
Subject:
primary_tumor
(Tumor tissue)
→
was_positive_for
→
Object:
von_Willebrand_factor
(Protein markers)
Original: The primary tumor and the lung metastases#were positive for#von Willebrand factor and vimentin
#17769
middle Confidence
Subject:
Duodenal_polyp
(polyp)
→
contains
→
Object:
gastric_epithelial_tumor
(Gastric epithelial tumors)
Original: Duodenal polyp#contains#a gastric epithelial tumor within a lipoma
#17768
middle Confidence
Subject:
EBER1
(Noncoding RNA)
→
is_present_in
→
Object:
squamous_cell_carcinoma
(Squamous cell carcinoma)
Original: EBER1#is present in#two adenocarcinomas and two squamous cell carcinomas
#17767
middle Confidence
Subject:
EBER1
(Noncoding RNA)
→
is_present_in
→
Object:
adenocarcinoma
(Adenocarcinoma)
Original: EBER1#is present in#two adenocarcinomas and two squamous cell carcinomas
#17766
middle Confidence
Subject:
Intraabdominal_tumor_cells
(Tumor cells)
→
display
→
Object:
clear_cytoplasm
(Clear cytoplasm)
Original: Intraabdominal tumor cells#display#hyperchromatic nucleus/ prominent nucleoli/ and clear cytoplasm
#17765
middle Confidence
Subject:
Intraabdominal_tumor_cells
(Tumor cells)
→
display
→
Object:
prominent_nucleoli
(Obvious nucleolus)
Original: Intraabdominal tumor cells#display#hyperchromatic nucleus/ prominent nucleoli/ and clear cytoplasm
#17764
middle Confidence
Subject:
Intraabdominal_tumor_cells
(Tumor cells)
→
display
→
Object:
hyperchromatic_nucleus
(Darkly stained nuclei)
Original: Intraabdominal tumor cells#display#hyperchromatic nucleus/ prominent nucleoli/ and clear cytoplasm
#17736
middle Confidence
Subject:
adrenocortical_carcinoma
(Tumor type)
→
resembles
→
Object:
low_grade_neuroendocrine_tumor
(Neuroendocrine tumors)
Original: Primary and metastatic ACCs#resemble#benign cortical lesion or low-grade neuroendocrine tumor
#17735
middle Confidence
Subject:
adrenocortical_carcinoma
(Tumor type)
→
resembles
→
Object:
benign_cortical_lesion
(Benign lesions)
Original: Primary and metastatic ACCs#resemble#benign cortical lesion or low-grade neuroendocrine tumor
#17734
middle Confidence
Subject:
cytomorphologic_changes_in_Graves_disease
(Tissue morphology)
→
may_mimic
→
Object:
nuclear_features_of_papillary_thyroid_carcinoma
(Nuclear characteristics)
Original: Cytomorphologic changes in GD#may mimic#nuclear features of papillary thyroid carcinoma
#17729
middle Confidence
Subject:
Cytologic_findings_in_fine_needle_aspiration_biopsy
(Cytology)
→
reported_from
→
Object:
Wilms_tumor
(Disease Type)
Original: Cytologic findings in fine needle aspiration biopsy#are reported from#ten cases of Wilms' tumor
#17726
middle Confidence
Subject:
breast_cancers_with_BRCA2_mutation
(Tumor type)
→
differ_from
→
Object:
sporadic_breast_cancers_in_histopathologic_appearance
(Tumor morphological characteristics)
Original: Breast cancers associated with BRCA1 and BRCA2 mutations#differ from#sporadic cancers in histopathologic appearances
#17725
middle Confidence
Subject:
breast_cancers_with_BRCA1_mutation
(Tumor type)
→
differ_from
→
Object:
sporadic_breast_cancers_in_histopathologic_appearance
(Tumor morphological characteristics)
Original: Breast cancers associated with BRCA1 and BRCA2 mutations#differ from#sporadic cancers in histopathologic appearances
#17708
middle Confidence
Subject:
Neuroendocrine differentiation
(Cell differentiation characteristics)
→
is_identified_by
→
Object:
speckled chromatin patterns
(Cell morphological characteristics)
Original: Neuroendocrine differentiation#is identified by#loose cell aggregates/ rosette formations/ and speckled chromatin patterns
#17707
middle Confidence
Subject:
Neuroendocrine differentiation
(Cell differentiation characteristics)
→
is_identified_by
→
Object:
rosette formations
(Cell morphological characteristics)
Original: Neuroendocrine differentiation#is identified by#loose cell aggregates/ rosette formations/ and speckled chromatin patterns
#17706
middle Confidence
Subject:
Neuroendocrine differentiation
(Cell differentiation characteristics)
→
is_identified_by
→
Object:
loose cell aggregates
(Cell morphological characteristics)
Original: Neuroendocrine differentiation#is identified by#loose cell aggregates/ rosette formations/ and speckled chromatin patterns
#17703
middle Confidence
Subject:
GCT_of_the_breast
(Tumor type)
→
shows
→
Object:
sheets_of_large_granular_cells
(Cell morphology)
Original: Cytomorphological features of GCT#include#sheets of large granular cells intersected by arborizing thin-walled blood vessels
#17702
middle Confidence
Subject:
hyperechogenicity
(Imaging features)
→
was_noted_in
→
Object:
GCT_of_the_breast
(Tumor type)
Original: Hyperechogenicity#was noted in#71% of GCT cases in this series
#17701
middle Confidence
Subject:
cyto-histopathological_database
(database)
→
was_searched_for
→
Object:
GCT_of_the_breast
(Tumor type)
Original: Cyto-histopathological database#was searched for#breast lesions with GCT diagnosis
#17700
middle Confidence
Subject:
LCNEC
(Tumor type)
→
is_characterized_by
→
Object:
high_mitotic_rate
(Cell proliferation characteristics)
Original: LCNEC#is characterized by#large cells with prominent nucleoli/ coarse chromatin/ and high mitotic rate
#17699
middle Confidence
Subject:
LCNEC
(Tumor type)
→
is_characterized_by
→
Object:
coarse_chromatin
(Cell morphology)
Original: LCNEC#is characterized by#large cells with prominent nucleoli/ coarse chromatin/ and high mitotic rate
#17698
middle Confidence
Subject:
LCNEC
(Tumor type)
→
is_characterized_by
→
Object:
large_cells_with_prominent_nucleoli
(Cell morphology)
Original: LCNEC#is characterized by#large cells with prominent nucleoli/ coarse chromatin/ and high mitotic rate
#17697
middle Confidence
Subject:
FH_deficiency
(Protein deficiency)
→
is_associated_with
→
Object:
ovoid_nuclei_in_chains
(Cell morphology)
Original: FH-d morphological features#include#staghorn vasculature/ alveolar-pattern edema/ scattered bizarre nuclei/ eosinophilic cytoplasmic inclusions/ significant eosinophilic nucleolus with peri-nucleolus hollowing/ ovoid nuclei in chains
#17696
middle Confidence
Subject:
FH_deficiency
(Protein deficiency)
→
is_associated_with
→
Object:
significant_eosinophilic_nucleolus_with_peri-nucleolus_hollowing
(Cell morphology)
Original: FH-d morphological features#include#staghorn vasculature/ alveolar-pattern edema/ scattered bizarre nuclei/ eosinophilic cytoplasmic inclusions/ significant eosinophilic nucleolus with peri-nucleolus hollowing/ ovoid nuclei in chains
#17695
middle Confidence
Subject:
FH_deficiency
(Protein deficiency)
→
is_associated_with
→
Object:
eosinophilic_cytoplasmic_inclusions
(Cell morphology)
Original: FH-d morphological features#include#staghorn vasculature/ alveolar-pattern edema/ scattered bizarre nuclei/ eosinophilic cytoplasmic inclusions/ significant eosinophilic nucleolus with peri-nucleolus hollowing/ ovoid nuclei in chains
#17694
middle Confidence
Subject:
FH_deficiency
(Protein deficiency)
→
is_associated_with
→
Object:
scattered_bizarre_nuclei
(Cell morphology)
Original: FH-d morphological features#include#staghorn vasculature/ alveolar-pattern edema/ scattered bizarre nuclei/ eosinophilic cytoplasmic inclusions/ significant eosinophilic nucleolus with peri-nucleolus hollowing/ ovoid nuclei in chains
#17693
middle Confidence
Subject:
FH_deficiency
(Protein deficiency)
→
is_associated_with
→
Object:
alveolar-pattern_edema
(Tissue morphology)
Original: FH-d morphological features#include#staghorn vasculature/ alveolar-pattern edema/ scattered bizarre nuclei/ eosinophilic cytoplasmic inclusions/ significant eosinophilic nucleolus with peri-nucleolus hollowing/ ovoid nuclei in chains
#17692
middle Confidence
Subject:
FH_deficiency
(Protein deficiency)
→
is_associated_with
→
Object:
staghorn_vasculature
(Tissue morphology)
Original: FH-d morphological features#include#staghorn vasculature/ alveolar-pattern edema/ scattered bizarre nuclei/ eosinophilic cytoplasmic inclusions/ significant eosinophilic nucleolus with peri-nucleolus hollowing/ ovoid nuclei in chains
#17684
middle Confidence
Subject:
cytokeratin_AE3
(Cytokeratin AE3)
→
shows_positive_reaction_in
→
Object:
tumor
(Tumor)
Original: Positive reaction#was evident for#epithelial membrane antigen/ keratin/ and cytokeratin AE3
#17683
middle Confidence
Subject:
keratin
(Keratin)
→
shows_positive_reaction_in
→
Object:
tumor
(Tumor)
Original: Positive reaction#was evident for#epithelial membrane antigen/ keratin/ and cytokeratin AE3
#17682
middle Confidence
Subject:
epithelial_membrane_antigen
(Cell membrane antigen)
→
shows_positive_reaction_in
→
Object:
tumor
(Tumor)
Original: Positive reaction#was evident for#epithelial membrane antigen/ keratin/ and cytokeratin AE3
#17658
middle Confidence
Subject:
fine_needle_aspiration_cytology
(Diagnostic Tools)
→
can_offer
→
Object:
diagnosis_of_GCT_at_extagonadal_sites
(Diagnosis conclusion)
Original: Fine-needle aspiration cytology#can offer#a diagnosis of GCT at extragonadal sites
#17625
middle Confidence
Subject:
biopsy_of_enlarged_parotid_gland
(Tissue biopsy)
→
shows
→
Object:
nucleoli_corresponding_to_immunoblasts
(Cell morphology)
Original: Biopsy of enlarged parotid gland#showed#lymphoid tumor tissue with blast appearance and nucleoli corresponding to centroblasts and immunoblasts
#17624
middle Confidence
Subject:
biopsy_of_enlarged_parotid_gland
(Tissue biopsy)
→
shows
→
Object:
nucleoli_corresponding_to_centroblasts
(Cell morphology)
Original: Biopsy of enlarged parotid gland#showed#lymphoid tumor tissue with blast appearance and nucleoli corresponding to centroblasts and immunoblasts
#17623
middle Confidence
Subject:
biopsy_of_enlarged_parotid_gland
(Tissue biopsy)
→
shows
→
Object:
lymphoid_tumor_tissue_with_blast_appearance
(Histological characteristics)
Original: Biopsy of enlarged parotid gland#showed#lymphoid tumor tissue with blast appearance and nucleoli corresponding to centroblasts and immunoblasts
#17622
middle Confidence
Subject:
effusion_cytology
(Cytological analysis)
→
is_analyzed_using
→
Object:
immunocytochemical_methods
(Analytical methods)
Original: Effusion cytology of MM/ AMM/ and melanotic MM cases#is analyzed using#cytomorphological/ immunohistochemical/ and immunocytochemical methods
#17621
middle Confidence
Subject:
effusion_cytology
(Cytological analysis)
→
is_analyzed_using
→
Object:
immunohistochemical_methods
(Analytical methods)
Original: Effusion cytology of MM/ AMM/ and melanotic MM cases#is analyzed using#cytomorphological/ immunohistochemical/ and immunocytochemical methods
#17620
middle Confidence
Subject:
effusion_cytology
(Cytological analysis)
→
is_analyzed_using
→
Object:
cytomorphological_methods
(Analytical methods)
Original: Effusion cytology of MM/ AMM/ and melanotic MM cases#is analyzed using#cytomorphological/ immunohistochemical/ and immunocytochemical methods
#17619
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Pathological diagnosis technology)
→
shows
→
Object:
ganglion_cell-like_cells
(Cell morphology)
Original: FNAB#showed#loose clusters of uniform/ fibroblastlike spindle cells and admixed large/ ganglion cell-like cells
#17618
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Pathological diagnosis technology)
→
shows
→
Object:
fibroblastlike_spindle_cells
(Cell morphology)
Original: FNAB#showed#loose clusters of uniform/ fibroblastlike spindle cells and admixed large/ ganglion cell-like cells
#17604
middle Confidence
Subject:
tumor
(Tumor tissue)
→
was_diagnosed_as
→
Object:
malignant_melanoma_with_rhabdoid_phenotype
(Disease phenotype)
Original: tumor#was diagnosed as#malignant melanoma with a rhabdoid phenotype
#17592
middle Confidence
Subject:
CD1c_expression
(Protein expression)
→
is_detected_in
→
Object:
B-NHL
(Hematologic malignancies)
Original: CD1c expression#is detected in#B-cell chronic lymphocytic leukemias and B non-Hodgkin's lymphomas
#17591
middle Confidence
Subject:
CD1c_expression
(Protein expression)
→
is_detected_in
→
Object:
B-CLL
(Hematologic malignancies)
Original: CD1c expression#is detected in#B-cell chronic lymphocytic leukemias and B non-Hodgkin's lymphomas
#17563
middle Confidence
Subject:
large_cell_neuroblastoma
(Tumor type)
→
is_distinct_entity_within
→
Object:
neuroblastoma
(Tumor type)
Original: authors#propose#LCN as a distinct entity within neuroblastoma
#17562
middle Confidence
Subject:
large_cell_neuroblastoma
(Tumor type)
→
is
→
Object:
distinct_phenotype_of_neuroblastoma
(Tumor phenotype)
Original: large cell neuroblastoma#is#a distinct phenotype of neuroblastoma with aggressive behavior
#17545
middle Confidence
Subject:
imaging
(Medical Imaging)
→
shows
→
Object:
invasion_into_surrounding_structures
(Histological characteristics)
Original: Imaging#showed#nasal cavity and ethmoid sinus mass with invasion into surrounding structures and bone destruction
#17544
middle Confidence
Subject:
imaging
(Medical Imaging)
→
shows
→
Object:
bone_destruction
(Bone destruction characteristics)
Original: Imaging#showed#nasal cavity and ethmoid sinus mass with invasion into surrounding structures and bone destruction
#17543
middle Confidence
Subject:
imaging
(Medical Imaging)
→
shows
→
Object:
ethmoid_sinus_mass
(Tumor)
Original: Imaging#showed#nasal cavity and ethmoid sinus mass with invasion into surrounding structures and bone destruction
#17542
middle Confidence
Subject:
imaging
(Medical Imaging)
→
shows
→
Object:
nasal_cavity_mass
(Tumor)
Original: Imaging#showed#nasal cavity and ethmoid sinus mass with invasion into surrounding structures and bone destruction
#17540
middle Confidence
Subject:
immunophenotype
(Immunophenotype)
→
is_investigated_in
→
Object:
sinonasal_renal_cell_like_adenocarcinoma
(Tumor)
Original: Study#investigated#clinicopathological features/ immunophenotype/ and prognosis of sinonasal renal cell-like adenocarcinoma
#17536
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
show
→
Object:
irregular_nuclei_with_granular_chromatin_and_frequent_nucleoli
(Cell morphology)
Original: neoplastic cells#showed#irregular nuclei with granular chromatin and frequent nucleoli
#17535
middle Confidence
Subject:
FNA_samples
(Histological samples)
→
demonstrates
→
Object:
epithelioid_cells_with_rhabdoid_morphology_and_cytoplasmic_bodies
(Cell morphology)
Original: FNA samples#demonstrated#epithelioid cells with rhabdoid morphology and cytoplasmic bodies
#17528
middle Confidence
Subject:
Imprint_cytology
(Pathological technology)
→
showed
→
Object:
neoplastic_cells_with_peripherally_displaced_nucleus
(Tumor cell phenotype)
Original: Imprint cytology#showed#neoplastic cells were crowded with some cells having a peripherally displaced nucleus
#17513
middle Confidence
Subject:
MiB1_staining
(Molecular markers)
→
helps_to_separate
→
Object:
atypical_fibroxanthoma
(Disease diagnosis)
Original: MiB1 staining#helps to separate#atypical cutaneous fibrous histiocytoma from atypical fibroxanthoma
#17512
middle Confidence
Subject:
MiB1_staining
(Molecular markers)
→
helps_to_separate
→
Object:
atypical_cutaneous_fibrous_histiocytoma
(Disease diagnosis)
Original: MiB1 staining#helps to separate#atypical cutaneous fibrous histiocytoma from atypical fibroxanthoma
#17497
middle Confidence
Subject:
familiarity_with_cytologic_features
(Pathology knowledge)
→
contributes_to
→
Object:
correct_diagnosis
(Diagnostic outcome)
Original: Correct diagnosis#can be achieved with#a combination of awareness of the lesion/ familiarity with characteristic cytologic features/ and application of appropriate immunohistochemistry markers
#17496
middle Confidence
Subject:
awareness_of_lesion
(Clinical cognition)
→
contributes_to
→
Object:
correct_diagnosis
(Diagnostic outcome)
Original: Correct diagnosis#can be achieved with#a combination of awareness of the lesion/ familiarity with characteristic cytologic features/ and application of appropriate immunohistochemistry markers
#17495
middle Confidence
Subject:
material_obtained_by_fine-needle_aspiration
(Source)
→
renders
→
Object:
definitive_diagnosis_of_MMSP
(Diagnostic behavior)
Original: Definitive diagnosis of MMSP#was rendered on#material obtained by fine-needle aspiration
#17494
middle Confidence
Subject:
immunohistochemical_study
(Detection Technology)
→
demonstrated
→
Object:
high_proliferative_index_by_Ki-67
(Protein expression)
Original: Immunohistochemical study#demonstrated#loss of myoepithelial differentiation/ overexpression of p53/ and high proliferative index by Ki-67
#17493
middle Confidence
Subject:
immunohistochemical_study
(Detection Technology)
→
demonstrated
→
Object:
overexpression_of_p53
(Protein expression)
Original: Immunohistochemical study#demonstrated#loss of myoepithelial differentiation/ overexpression of p53/ and high proliferative index by Ki-67
#17489
middle Confidence
Subject:
neuroendocrine_markers
(Biomarkers)
→
aid_in
→
Object:
diagnosis_of_neuroendocrine_tumors
(Diagnostic Process)
Original: neuroendocrine markers#aid in#diagnosis of neuroendocrine tumors
#17488
middle Confidence
Subject:
pathologic_characteristics
(Pathological characteristics)
→
is_helpful_in_distinguishing
→
Object:
benign_inflammatory_fibromyxoid_lesions
(Disease phenotype)
Original: awareness of clinical and pathologic characteristics#is helpful in distinguishing#benign inflammatory fibromyxoid lesions
#17487
middle Confidence
Subject:
clinical_characteristics
(Clinical characteristics)
→
is_helpful_in_distinguishing
→
Object:
benign_inflammatory_fibromyxoid_lesions
(Disease phenotype)
Original: awareness of clinical and pathologic characteristics#is helpful in distinguishing#benign inflammatory fibromyxoid lesions
#17463
middle Confidence
Subject:
diagnosis
(Diagnostic behavior)
→
confirmed_by
→
Object:
CD35
(Protein receptor)
Original: Diagnosis#was confirmed by#positive immunoreactivity with CD21 and CD35 antibodies
#17462
middle Confidence
Subject:
diagnosis
(Diagnostic behavior)
→
confirmed_by
→
Object:
CD21
(Protein receptor)
Original: Diagnosis#was confirmed by#positive immunoreactivity with CD21 and CD35 antibodies
#17459
middle Confidence
Subject:
primary_pigmented_lesions_of_CNS
(disease)
→
are_categorized_by
→
Object:
dermatopathologic_nomenclature
(Diagnostic Methods)
Original: Primary pigmented lesions of CNS#are categorized by#dermatopathologic nomenclature
#17451
middle Confidence
Subject:
Malignant_tissue
(Malignant tissue)
→
was_found_in
→
Object:
biopsy_specimens
(Tissue samples)
Original: Malignant tissue#was found in#two-thirds of the biopsy specimens
#17450
middle Confidence
Subject:
Biopsy
(Biopsy)
→
was_performed_in
→
Object:
women_with_radiotherapy_for_gynecologic_carcinoma
(Patient characteristics)
Original: Biopsy#was performed in#40 women who had received radiotherapy for gynecologic carcinoma
#17445
middle Confidence
Subject:
paraffin_embedded_endoscopic_biopsies
(Tissue samples)
→
classified_into
→
Object:
neoplastic_mucosa
(Tumor tissue)
Original: Paraffin-embedded endoscopic biopsies#are classified into#normal/ inflammatory/ dysplastic/ and neoplastic mucosa
#17444
middle Confidence
Subject:
paraffin_embedded_endoscopic_biopsies
(Tissue samples)
→
classified_into
→
Object:
dysplastic_mucosa
(Abnormal proliferation of tissue)
Original: Paraffin-embedded endoscopic biopsies#are classified into#normal/ inflammatory/ dysplastic/ and neoplastic mucosa
#17443
middle Confidence
Subject:
paraffin_embedded_endoscopic_biopsies
(Tissue samples)
→
classified_into
→
Object:
inflammatory_mucosa
(Inflammatory tissue)
Original: Paraffin-embedded endoscopic biopsies#are classified into#normal/ inflammatory/ dysplastic/ and neoplastic mucosa
#17442
middle Confidence
Subject:
paraffin_embedded_endoscopic_biopsies
(Tissue samples)
→
classified_into
→
Object:
normal_mucosa
(Normal tissue)
Original: Paraffin-embedded endoscopic biopsies#are classified into#normal/ inflammatory/ dysplastic/ and neoplastic mucosa
#17430
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_immunoreactive_for
→
Object:
CD56
(Cell adhesion molecules)
Original: Neoplastic cells#were immunoreactive for#thyroid transcription factor 1 and CD56
#17429
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_immunoreactive_for
→
Object:
thyroid_transcription_factor_1
(Transcription Factors)
Original: Neoplastic cells#were immunoreactive for#thyroid transcription factor 1 and CD56
#17426
middle Confidence
Subject:
Gallbladder_carcinoma
(Tumor diseases)
→
was_reanalyzed_for
→
Object:
entity-defining_characteristics
(Disease phenotype)
Original: Gallbladder carcinomas#were re-analyzed for#entity-defining characteristics
#17422
middle Confidence
Subject:
TTF1-positive_NSCLC
(Tumor type)
→
displays
→
Object:
PTC-like_features
(Histological characteristics)
Original: adenocarcinomas and TTF1-positive NSCLCs#displayed#PTC-like features (papillae/ nuclear grooves/ chromatin clearing)
#17421
middle Confidence
Subject:
adenocarcinoma
(Tumor type)
→
displays
→
Object:
PTC-like_features
(Histological characteristics)
Original: adenocarcinomas and TTF1-positive NSCLCs#displayed#PTC-like features (papillae/ nuclear grooves/ chromatin clearing)
#17407
middle Confidence
Subject:
IVLBCL_tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD5
(Membrane receptor protein)
Original: IVLBCL tumor cells#are positive for#CD5 in 2 cases
#17404
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
variably_express
→
Object:
smooth-muscle_actin
(Protein markers)
Original: Tumor cells#variably express#CD31/ CD34/ factor VIII-Rag/ and smooth-muscle actin
#17403
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
variably_express
→
Object:
factor_VIII-Rag
(Protein markers)
Original: Tumor cells#variably express#CD31/ CD34/ factor VIII-Rag/ and smooth-muscle actin
#17402
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
variably_express
→
Object:
CD34
(Protein markers)
Original: Tumor cells#variably express#CD31/ CD34/ factor VIII-Rag/ and smooth-muscle actin
#17401
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
variably_express
→
Object:
CD31
(Protein markers)
Original: Tumor cells#variably express#CD31/ CD34/ factor VIII-Rag/ and smooth-muscle actin
#17400
middle Confidence
Subject:
High-grade_endometrial_stromal_sarcoma
(Tumor type)
→
display
→
Object:
enlarged_round_cells_with_smooth_nuclear_membranes
(Cell morphology)
Original: High-grade tumors#display#enlarged round cells with smooth nuclear membranes
#17397
middle Confidence
Subject:
anterior_uveal_melanocytoma
(Tumor type)
→
is_described_as
→
Object:
uncommon_benign_melanocytic_tumor
(Tumor type)
Original: Anterior uveal melanocytomas#are described as#uncommon benign melanocytic tumors
#17385
middle Confidence
Subject:
hepatocellular_carcinoma
(Cancer Type)
→
can_be_designated_as
→
Object:
DNA_aneuploid
(Chromosome ploidy status)
Original: Hepatocellular carcinoma#can be designated as#DNA diploid/ polyploid/ or aneuploid
#17384
middle Confidence
Subject:
hepatocellular_carcinoma
(Cancer Type)
→
can_be_designated_as
→
Object:
DNA_polyploid
(Chromosome ploidy status)
Original: Hepatocellular carcinoma#can be designated as#DNA diploid/ polyploid/ or aneuploid
#17383
middle Confidence
Subject:
hepatocellular_carcinoma
(Cancer Type)
→
can_be_designated_as
→
Object:
DNA_diploid
(Chromosome ploidy status)
Original: Hepatocellular carcinoma#can be designated as#DNA diploid/ polyploid/ or aneuploid
#17377
middle Confidence
Subject:
Basaloid_nests
(Tumor cell structure)
→
exhibit
→
Object:
prominent_nucleoli
(Nuclear morphology)
Original: Basaloid nests#exhibit#hyperchromatic nuclei with open nuclear chromatin/ prominent nucleoli/ and frequent mitoses
#17376
middle Confidence
Subject:
Basaloid_nests
(Tumor cell structure)
→
exhibit
→
Object:
hyperchromatic_nuclei
(Nuclear morphology)
Original: Basaloid nests#exhibit#hyperchromatic nuclei with open nuclear chromatin/ prominent nucleoli/ and frequent mitoses
#17375
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
display
→
Object:
small_size_with_scant_cytoplasm
(Cell morphology)
Original: Tumor cells#are#small with scant cytoplasm
#17351
middle Confidence
Subject:
Invasive lobular carcinoma
(Tumor)
→
is_classified_as
→
Object:
histiocytoid feature
(Histological characteristics)
Original: Invasive lobular carcinoma#is classified as#histiocytoid features
#17348
middle Confidence
Subject:
Small_cell_component
(Tumor cells)
→
stains_for
→
Object:
keratin
(protein)
Original: Small cell component#stains for#keratin
#17335
middle Confidence
Subject:
NEC_element
(Tumor composition)
→
showed
→
Object:
diffuse_proliferation_of_primitive_cancer_cells
(Cellular Processes)
Original: NEC element#showed#diffuse proliferation of primitive cancer cells with fine-granular cytoplasm and nuclei with prominent nucleoli
#17333
middle Confidence
Subject:
Immunohistochemistry
(Immunohistochemistry)
→
helps_to_distinguish
→
Object:
malignant_gastrointestinal_neuroectodermal_tumor
(Tumor diseases)
Original: careful attentions to histomorphology and immunohistochemistry#can help to distinguish#this tumor from its mimickers
#17332
middle Confidence
Subject:
histomorphology
(Pathological morphological features)
→
helps_to_distinguish
→
Object:
malignant_gastrointestinal_neuroectodermal_tumor
(Tumor diseases)
Original: careful attentions to histomorphology and immunohistochemistry#can help to distinguish#this tumor from its mimickers
#17323
middle Confidence
Subject:
Histopathologic_features
(Histological characteristics)
→
distinguishes
→
Object:
other_non-small_cell_lung_cancers
(Tumor phenotype)
Original: Histopathologic features#distinguish#this tumor from other non-small cell lung cancers
#17322
middle Confidence
Subject:
Histopathologic_features
(Histological characteristics)
→
distinguishes
→
Object:
this_tumor
(Tumor phenotype)
Original: Histopathologic features#distinguish#this tumor from other non-small cell lung cancers
#17321
middle Confidence
Subject:
intraoperative_cytologic_sample
(Intraoperative cytology samples)
→
showed
→
Object:
conspicuous_nucleoli
(Nucleolar characteristics)
Original: Intraoperative cytologic sample#showed#necrotic background with malignant cells and conspicuous nucleoli
#17320
middle Confidence
Subject:
intraoperative_cytologic_sample
(Intraoperative cytology samples)
→
showed
→
Object:
malignant_cells
(Tumor cells)
Original: Intraoperative cytologic sample#showed#necrotic background with malignant cells and conspicuous nucleoli
#17319
middle Confidence
Subject:
intraoperative_cytologic_sample
(Intraoperative cytology samples)
→
showed
→
Object:
necrotic_background
(Organizational characteristics)
Original: Intraoperative cytologic sample#showed#necrotic background with malignant cells and conspicuous nucleoli
#17294
middle Confidence
Subject:
AgNOR_score
(Molecular markers)
→
higher_than
→
Object:
borderline_lesion_AgNOR_score
(Molecular markers)
Original: AgNOR scores for hepatocellular carcinomas (HCC)#were significantly higher than#scores for benign and borderline lesions
#17293
middle Confidence
Subject:
AgNOR_score
(Molecular markers)
→
higher_than
→
Object:
benign_lesion_AgNOR_score
(Molecular markers)
Original: AgNOR scores for hepatocellular carcinomas (HCC)#were significantly higher than#scores for benign and borderline lesions
#17279
middle Confidence
Subject:
AgNOR_number
(Nuclear markers)
→
is_higher_in
→
Object:
malignant_prostatic_tissue
(Malignant tissue)
Original: number of AgNORs#is higher in#malignant prostatic tissue than in normal or hyperplastic prostatic tissue
#17264
middle Confidence
Subject:
intraluminal_amorphous_eosinophilic_material
(Organizational structure)
→
was_observed_in
→
Object:
malignant_specimens
(Pathological samples)
Original: Intraluminal amorphous eosinophilic material#was observed in#86.7% of malignant specimens
#17263
middle Confidence
Subject:
intraluminal_crystalloids
(Organizational structure)
→
were_observed_in
→
Object:
malignant_specimens
(Pathological samples)
Original: Intraluminal crystalloids#were observed in#40.6% of malignant specimens
#17256
middle Confidence
Subject:
quantitative_evaluation_of_nucleolar_features
(Molecular analysis methods)
→
is_applied_in
→
Object:
brain_tumor_diagnosis
(Diagnostic Process)
Original: Quantitative evaluation of nucleolar features#is applied in#brain tumor diagnosis
#17194
middle Confidence
Subject:
anaplasia
(Cell morphology phenotype)
→
is
→
Object:
cytomorphological_criterion_of_malignancy
(Pathological criteria)
Original: Anaplasia#is#a cytomorphological criterion of malignancy
#17071
middle Confidence
Subject:
BCL2
(Protein coding genes)
→
is_expressed_in
→
Object:
squamous_cell_carcinoma_of_larynx
(Tumor)
Original: expression of p53 and bcl-2#was determined in#SCC of the larynx
#17070
middle Confidence
Subject:
TP53
(Protein coding genes)
→
is_expressed_in
→
Object:
squamous_cell_carcinoma_of_larynx
(Tumor)
Original: expression of p53 and bcl-2#was determined in#SCC of the larynx
#16886
middle Confidence
Subject:
Lower_ER_immunoreactivity
(Protein expression level)
→
is_detected_in
→
Object:
30%_of_breast_cancer_biopsies
(Clinical samples)
Original: Lower ER immunoreactivity#is detected in#30% of breast cancer biopsies
#16669
middle Confidence
Subject:
MaxVision_immunohistochemical_staining
(Immunohistochemical staining)
→
is_used_to_detect
→
Object:
p53_expression
(p53 protein expression)
Original: MaxVision immunohistochemical staining#is used to detect#the expression of Ki-67/ p16/ and p53 proteins
#16668
middle Confidence
Subject:
MaxVision_immunohistochemical_staining
(Immunohistochemical staining)
→
is_used_to_detect
→
Object:
p16_expression
(p16 protein expression)
Original: MaxVision immunohistochemical staining#is used to detect#the expression of Ki-67/ p16/ and p53 proteins
#16667
middle Confidence
Subject:
MaxVision_immunohistochemical_staining
(Immunohistochemical staining)
→
is_used_to_detect
→
Object:
Ki-67_expression
(Ki-67 protein expression)
Original: MaxVision immunohistochemical staining#is used to detect#the expression of Ki-67/ p16/ and p53 proteins
#16666
middle Confidence
Subject:
Cellular_proliferative_indices
(Cell proliferation index)
→
are_compared_with
→
Object:
AgNOR_expression
(AgNOR expression)
Original: Cellular proliferative indices in AH nodules#are compared with#other liver nodules using PCNA monoclonal antibody and AgNOR
#16665
middle Confidence
Subject:
Cellular_proliferative_indices
(Cell proliferation index)
→
are_compared_with
→
Object:
PCNA_expression
(PCNA expression)
Original: Cellular proliferative indices in AH nodules#are compared with#other liver nodules using PCNA monoclonal antibody and AgNOR
#16643
middle Confidence
Subject:
AgNOR_counts
(Molecular analysis indicators)
→
is_evaluated_in
→
Object:
endocervical_carcinoma
(Malignant tumors)
Original: AgNOR counts#are evaluated in#endometrial and endocervical carcinomas
#16642
middle Confidence
Subject:
AgNOR_counts
(Molecular analysis indicators)
→
is_evaluated_in
→
Object:
endometrial_carcinoma
(Malignant tumors)
Original: AgNOR counts#are evaluated in#endometrial and endocervical carcinomas
#16606
middle Confidence
Subject:
tumors
(Tumor Entities)
→
detected_incidentally_by
→
Object:
imaging_studies
(Medical imaging technology)
Original: Tumors#were found#incidentally on imaging studies
#16566
middle Confidence
Subject:
AgNORs
(Silver-stained nucleolar organizing region)
→
identified_in
→
Object:
breast_carcinomas
(Breast cancer)
Original: AgNORs#identified in#breast carcinomas
#16557
middle Confidence
Subject:
mitotic_density
(Mitotic density)
→
is_quantified_for
→
Object:
CIN_3
(High-grade cervical intraepithelial neoplasia)
Original: Mitotic activity index and density#are quantified for#high-grade cervical intraepithelial neoplasia (CIN 3)
#16556
middle Confidence
Subject:
mitotic_activity_index
(Mitotic activity index)
→
is_quantified_for
→
Object:
CIN_3
(High-grade cervical intraepithelial neoplasia)
Original: Mitotic activity index and density#are quantified for#high-grade cervical intraepithelial neoplasia (CIN 3)
#16533
middle Confidence
Subject:
TP53
(Tumor suppressor proteins)
→
is_expressed_in
→
Object:
neoplastic_lesions
(Lesion type)
Original: PCNA/ AgNOR/ oncogenes/ and tumor suppressor gene p53#are expressed in#preneoplastic and neoplastic lesions of rat and human livers
#16532
middle Confidence
Subject:
TP53
(Tumor suppressor proteins)
→
is_expressed_in
→
Object:
preneoplastic_lesions
(Lesion type)
Original: PCNA/ AgNOR/ oncogenes/ and tumor suppressor gene p53#are expressed in#preneoplastic and neoplastic lesions of rat and human livers
#16531
middle Confidence
Subject:
AgNOR_activity
(Molecular activity)
→
is_higher_in
→
Object:
carcinomas
(Tumor type)
Original: AgNOR activity#is higher in#carcinomas compared to benign tumors/ chronic nasopharyngitis/ and normal nasopharyngeal tissues
#16530
middle Confidence
Subject:
NOR_staining_technique
(Dyeing technology)
→
provides
→
Object:
intraoperative_evaluation_of_proliferative_activity
(Cellular process assessment)
Original: NOR staining technique#provides#intraoperative evaluation of proliferative activity in cerebral neoplasms
#16526
middle Confidence
Subject:
Ploidy
(ploidy)
→
correlates_with
→
Object:
histologic_diagnosis
(Pathological diagnosis)
Original: ploidy#correlates with#histologic diagnosis
#16520
middle Confidence
Subject:
ASC-H_case
(Clinical Cases)
→
showed
→
Object:
HSIL
(Disease phenotype)
Original: ASC-H cases#showed#HSIL/ LSIL/ squamous metaplasia/ reactive changes/ benign glandular lesions/ and atrophy
#16511
middle Confidence
Subject:
nuclear_changes
(Nuclear changes)
→
indicate
→
Object:
dysplasia_progression
(Dysplasia progression)
Original: Changes in nuclei#indicate#progression in dysplasia spectrum
#16496
middle Confidence
Subject:
pancreatic_lesions
(Tissue lesions)
→
were_identified_as
→
Object:
epithelial_origin
(Epithelial origin)
Original: 22 cases of pancreatic lesions#were identified as#neoplastic/ including epithelial origin cases
#16495
middle Confidence
Subject:
pancreatic_lesions
(Tissue lesions)
→
were_identified_as
→
Object:
neoplastic
(Tumor phenotype)
Original: 22 cases of pancreatic lesions#were identified as#neoplastic/ including epithelial origin cases
#16493
middle Confidence
Subject:
imaging_investigations
(Imaging tests)
→
disclosed
→
Object:
thickening_of_stomach_wall
(Thickening of the stomach wall)
Original: Imaging investigations#disclosed#enlargement of epigastric lymph nodes and thickening of stomach wall
#16492
middle Confidence
Subject:
imaging_investigations
(Imaging tests)
→
disclosed
→
Object:
enlargement_of_epigastric_lymph_nodes
(Swollen lymph nodes)
Original: Imaging investigations#disclosed#enlargement of epigastric lymph nodes and thickening of stomach wall
#16489
middle Confidence
Subject:
Biopsy
(Diagnostic techniques)
→
confirmed_as
→
Object:
LELC
(Tumor)
Original: Biopsy#diagnosed#invasive poorly differentiated carcinoma/ later confirmed as LELC on nephroureterectomy
#16488
middle Confidence
Subject:
Biopsy
(Diagnostic techniques)
→
diagnosed
→
Object:
invasive_poorly_differentiated_carcinoma
(Tumor)
Original: Biopsy#diagnosed#invasive poorly differentiated carcinoma/ later confirmed as LELC on nephroureterectomy
#16469
middle Confidence
Subject:
Cytologic_findings
(Histological information)
→
should_be_correlated_with
→
Object:
radiologic_information
(Imaging information)
Original: Cytologic findings#should be correlated with#clinical and radiologic information
#16468
middle Confidence
Subject:
Cytologic_findings
(Histological information)
→
should_be_correlated_with
→
Object:
clinical_information
(Clinical Information)
Original: Cytologic findings#should be correlated with#clinical and radiologic information
#16464
middle Confidence
Subject:
Resected_uterus
(organ)
→
showed
→
Object:
leiomyomatous_tumor
(Tumor type)
Original: Resected uterus#showed#a mixture of well to poorly differentiated adenocarcinoma and nonepithelial tumors
#16463
middle Confidence
Subject:
Resected_uterus
(organ)
→
showed
→
Object:
fibromatous_tumor
(Tumor type)
Original: Resected uterus#showed#a mixture of well to poorly differentiated adenocarcinoma and nonepithelial tumors
#16462
middle Confidence
Subject:
Resected_uterus
(organ)
→
showed
→
Object:
well_differentiated_adenocarcinoma
(Tumor type)
Original: Resected uterus#showed#a mixture of well to poorly differentiated adenocarcinoma and nonepithelial tumors
#16460
middle Confidence
Subject:
morphology_with_genetic_profiling
(Molecular detection technology)
→
analyzes
→
Object:
high_grade_neuroendocrine_carcinoma_of_colon
(Tumor diseases)
Original: Morphology with immunohistochemical and genetic profiling#analyzes#high-grade neuroendocrine carcinoma of colon
#16459
middle Confidence
Subject:
morphology_with_immunohistochemical_profiling
(Molecular detection technology)
→
analyzes
→
Object:
high_grade_neuroendocrine_carcinoma_of_colon
(Tumor diseases)
Original: Morphology with immunohistochemical and genetic profiling#analyzes#high-grade neuroendocrine carcinoma of colon
#16458
middle Confidence
Subject:
tumor_tissue
(Tumor tissue)
→
shows
→
Object:
atypical_large_epithelioid_cells
(Cell Type)
Original: tumor tissue#shows#typical syncytial growth pattern of atypical/ large/ epithelioid cells with ill-defined cytoplasmic borders/ prominent nucleoli/ and numerous mitoses
#16457
middle Confidence
Subject:
malignant_melanoma
(Tumor diseases)
→
originates_from
→
Object:
ovarian_mature_cystic_teratoma
(Primary tumor site)
Original: Malignant melanoma#originated from#ovarian mature cystic teratoma
#16454
middle Confidence
Subject:
granular_cell_tumor
(Tumor)
→
is_generally
→
Object:
benign
(Disease phenotype)
Original: Granular cell tumor#is generally#benign
#16432
middle Confidence
Subject:
Squamoid_nests
(Organizational Structure)
→
are
→
Object:
key_morphologic_feature_of_pancreatoblastoma
(Pathological characteristics)
Original: Squamoid nests#are#a key morphologic feature of pancreatoblastoma
#16431
middle Confidence
Subject:
Pancreatic_acinar_neoplasms
(Tumor type)
→
are_characterized_by
→
Object:
acinar_differentiation
(Cell differentiation characteristics)
Original: Pancreatic acinar neoplasms#are characterized by#acinar differentiation of at least a subset of neoplastic cells
#16430
middle Confidence
Subject:
Atypical_seminoma
(Tumor type)
→
presents_as
→
Object:
fragile_large_cells
(Cell morphology)
Original: Atypical seminoma#presents as#fragile large cells with scanty cytoplasm and vesicular nuclei
#16429
middle Confidence
Subject:
Malignant_fibrous_histiocytoma
(Tumor type)
→
is_defined_as
→
Object:
malignant_primary_bone_tumor
(Disease phenotype)
Original: Malignant fibrous histiocytoma#is defined as#a malignant primary bone tumor with fibrogenic and histiocytic cells
#16428
middle Confidence
Subject:
morphological_features
(Morphological characteristics)
→
helps_diagnose
→
Object:
metastatic_renal_cell_carcinoma
(Tumor type)
Original: Awareness of morphological features#helps diagnose#clear cell pancreatic NETs resembling metastatic renal cell carcinoma
#16427
middle Confidence
Subject:
morphological_features
(Morphological characteristics)
→
helps_diagnose
→
Object:
clear_cell_pancreatic_NETs
(Tumor type)
Original: Awareness of morphological features#helps diagnose#clear cell pancreatic NETs resembling metastatic renal cell carcinoma
#16404
middle Confidence
Subject:
tumors
(Tumor tissue)
→
are_misdiagnosed_as
→
Object:
craniopharyngiomas
(Tumor tissue)
Original: tumors#are misdiagnosed as#pituitary adenomas/ meningiomas/ and craniopharyngiomas
#16403
middle Confidence
Subject:
tumors
(Tumor tissue)
→
are_misdiagnosed_as
→
Object:
meningiomas
(Tumor tissue)
Original: tumors#are misdiagnosed as#pituitary adenomas/ meningiomas/ and craniopharyngiomas
#16402
middle Confidence
Subject:
tumors
(Tumor tissue)
→
are_misdiagnosed_as
→
Object:
pituitary_adenomas
(Tumor tissue)
Original: tumors#are misdiagnosed as#pituitary adenomas/ meningiomas/ and craniopharyngiomas
#16401
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
demonstrate_immunoreactivity_for
→
Object:
epithelial_membrane_antigen
(Diagnostic markers)
Original: tumor cells#demonstrate#immunoreactivity for vimentin/ D2-40/ CD34/ keratin(s)/ CD68/ actin(s)/ desmin/ S-100 protein/ and epithelial membrane antigen
#16400
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
demonstrate_immunoreactivity_for
→
Object:
S-100_protein
(Diagnostic markers)
Original: tumor cells#demonstrate#immunoreactivity for vimentin/ D2-40/ CD34/ keratin(s)/ CD68/ actin(s)/ desmin/ S-100 protein/ and epithelial membrane antigen
#16399
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
demonstrate_immunoreactivity_for
→
Object:
desmin
(Diagnostic markers)
Original: tumor cells#demonstrate#immunoreactivity for vimentin/ D2-40/ CD34/ keratin(s)/ CD68/ actin(s)/ desmin/ S-100 protein/ and epithelial membrane antigen
#16398
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
demonstrate_immunoreactivity_for
→
Object:
actin
(Diagnostic markers)
Original: tumor cells#demonstrate#immunoreactivity for vimentin/ D2-40/ CD34/ keratin(s)/ CD68/ actin(s)/ desmin/ S-100 protein/ and epithelial membrane antigen
#16397
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
demonstrate_immunoreactivity_for
→
Object:
CD68
(Diagnostic markers)
Original: tumor cells#demonstrate#immunoreactivity for vimentin/ D2-40/ CD34/ keratin(s)/ CD68/ actin(s)/ desmin/ S-100 protein/ and epithelial membrane antigen
#16396
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
demonstrate_immunoreactivity_for
→
Object:
keratin
(Diagnostic markers)
Original: tumor cells#demonstrate#immunoreactivity for vimentin/ D2-40/ CD34/ keratin(s)/ CD68/ actin(s)/ desmin/ S-100 protein/ and epithelial membrane antigen
#16395
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
demonstrate_immunoreactivity_for
→
Object:
CD34
(Diagnostic markers)
Original: tumor cells#demonstrate#immunoreactivity for vimentin/ D2-40/ CD34/ keratin(s)/ CD68/ actin(s)/ desmin/ S-100 protein/ and epithelial membrane antigen
#16394
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
demonstrate_immunoreactivity_for
→
Object:
D2-40
(Diagnostic markers)
Original: tumor cells#demonstrate#immunoreactivity for vimentin/ D2-40/ CD34/ keratin(s)/ CD68/ actin(s)/ desmin/ S-100 protein/ and epithelial membrane antigen
#16393
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
demonstrate_immunoreactivity_for
→
Object:
vimentin
(Diagnostic markers)
Original: tumor cells#demonstrate#immunoreactivity for vimentin/ D2-40/ CD34/ keratin(s)/ CD68/ actin(s)/ desmin/ S-100 protein/ and epithelial membrane antigen
#16392
middle Confidence
Subject:
Mast_cell_sarcoma
(Tumor)
→
shows_positivity_for
→
Object:
CD68
(Diagnostic markers)
Original: Staining#revealed positivity for#CD117/ mast cell tryptase/ CD13/ CD33/ CD43/ and CD68
#16391
middle Confidence
Subject:
Mast_cell_sarcoma
(Tumor)
→
shows_positivity_for
→
Object:
CD43
(Diagnostic markers)
Original: Staining#revealed positivity for#CD117/ mast cell tryptase/ CD13/ CD33/ CD43/ and CD68
#16390
middle Confidence
Subject:
Mast_cell_sarcoma
(Tumor)
→
shows_positivity_for
→
Object:
CD33
(Diagnostic markers)
Original: Staining#revealed positivity for#CD117/ mast cell tryptase/ CD13/ CD33/ CD43/ and CD68
#16389
middle Confidence
Subject:
Mast_cell_sarcoma
(Tumor)
→
shows_positivity_for
→
Object:
CD13
(Diagnostic markers)
Original: Staining#revealed positivity for#CD117/ mast cell tryptase/ CD13/ CD33/ CD43/ and CD68
#16388
middle Confidence
Subject:
Mast_cell_sarcoma
(Tumor)
→
shows_positivity_for
→
Object:
mast_cell_tryptase
(Diagnostic markers)
Original: Staining#revealed positivity for#CD117/ mast cell tryptase/ CD13/ CD33/ CD43/ and CD68
#16387
middle Confidence
Subject:
Mast_cell_sarcoma
(Tumor)
→
shows_positivity_for
→
Object:
CD117
(Diagnostic markers)
Original: Staining#revealed positivity for#CD117/ mast cell tryptase/ CD13/ CD33/ CD43/ and CD68
#16386
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
shows_patchy_staining_for
→
Object:
synaptophysin
(Diagnostic markers)
Original: Tumor cells#showed#patchy staining for INSM1 and synaptophysin
#16385
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
shows_patchy_staining_for
→
Object:
INSM1
(Diagnostic markers)
Original: Tumor cells#showed#patchy staining for INSM1 and synaptophysin
#16384
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
reacts_positively_to
→
Object:
Ulex_europaeus_lectin
(Diagnostic markers)
Original: Tumor cells#reacted positively to#Ulex europaeus lectin
#16370
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_focally_positive_for
→
Object:
desmin
(Structural proteins)
Original: Tumor cells#were#focally positive for desmin
#16369
middle Confidence
Subject:
fine_needle_aspiration_biopsy_findings
(Diagnostic techniques)
→
were_observed_in
→
Object:
lymphoepithelial_carcinoma_of_salivary_gland
(Tumor type)
Original: Fine needle aspiration biopsy findings#were observed in#lymphoepithelial carcinoma of salivary gland
#16368
middle Confidence
Subject:
cytology_findings
(Cytological characteristics)
→
were_observed_in
→
Object:
large_cell_neuroendocrine_carcinoma_of_uterine_cervix
(Tumor type)
Original: cytology findings#were observed in#large cell neuroendocrine carcinoma of uterine cervix
#16363
middle Confidence
Subject:
Tan_colored_eyelid_nodules_with_ulcer
(Clinical manifestations)
→
are_usually
→
Object:
basal_cell_carcinoma
(Tumor type)
Original: Tan-colored eyelid nodules with overlying ulcer#are usually#a basal cell carcinoma
#16360
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
are_sensitive_and_specific_for
→
Object:
distinguishing_NSCC
(Tumor)
Original: Cytologic features#are sensitive and specific for#distinguishing SCC from NSCC
#16359
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
are_sensitive_and_specific_for
→
Object:
distinguishing_SCC
(Tumor)
Original: Cytologic features#are sensitive and specific for#distinguishing SCC from NSCC
#16358
middle Confidence
Subject:
cytopathologic_differential_diagnosis
(Diagnostic Methods)
→
conducted_for
→
Object:
poorly_differentiated_non_small_cell_carcinoma
(Tumor)
Original: Cytopathologic differential diagnosis#was conducted for#small cell carcinoma and poorly differentiated non-small cell carcinoma
#16357
middle Confidence
Subject:
cytopathologic_differential_diagnosis
(Diagnostic Methods)
→
conducted_for
→
Object:
small_cell_carcinoma
(Tumor)
Original: Cytopathologic differential diagnosis#was conducted for#small cell carcinoma and poorly differentiated non-small cell carcinoma
#16356
middle Confidence
Subject:
nuclear_grooves
(Nuclear structural characteristics)
→
is_diagnostic_of
→
Object:
papillary_carcinoma
(Tumor)
Original: presence of nuclear grooves#is diagnostic of#thyroid neoplasms
#16355
middle Confidence
Subject:
nuclear_grooves
(Nuclear structural characteristics)
→
is_diagnostic_of
→
Object:
thyroid_neoplasms
(Tumor)
Original: presence of nuclear grooves#is diagnostic of#thyroid neoplasms
#16342
middle Confidence
Subject:
synaptophysin
(Neuroendocrine markers)
→
was_detected_in
→
Object:
tumor
(Malignant tumors)
Original: AE1/3/ CEA/ p63/ p16/ CD56/ chromogranin/ and synaptophysin#were detected in#tumor
#16341
middle Confidence
Subject:
Chromogranin
(Neuroendocrine markers)
→
was_detected_in
→
Object:
tumor
(Malignant tumors)
Original: AE1/3/ CEA/ p63/ p16/ CD56/ chromogranin/ and synaptophysin#were detected in#tumor
#16340
middle Confidence
Subject:
CD56
(Neural cell adhesion molecule)
→
was_detected_in
→
Object:
tumor
(Malignant tumors)
Original: AE1/3/ CEA/ p63/ p16/ CD56/ chromogranin/ and synaptophysin#were detected in#tumor
#16339
middle Confidence
Subject:
p16
(Cell cycle regulatory proteins)
→
was_detected_in
→
Object:
tumor
(Malignant tumors)
Original: AE1/3/ CEA/ p63/ p16/ CD56/ chromogranin/ and synaptophysin#were detected in#tumor
#16338
middle Confidence
Subject:
p63
(Transcription Factors)
→
was_detected_in
→
Object:
tumor
(Malignant tumors)
Original: AE1/3/ CEA/ p63/ p16/ CD56/ chromogranin/ and synaptophysin#were detected in#tumor
#16337
middle Confidence
Subject:
CEA
(CEA)
→
was_detected_in
→
Object:
tumor
(Malignant tumors)
Original: AE1/3/ CEA/ p63/ p16/ CD56/ chromogranin/ and synaptophysin#were detected in#tumor
#16336
middle Confidence
Subject:
AE1/3
(Cytokeratin)
→
was_detected_in
→
Object:
tumor
(Malignant tumors)
Original: AE1/3/ CEA/ p63/ p16/ CD56/ chromogranin/ and synaptophysin#were detected in#tumor
#16335
middle Confidence
Subject:
Tumor
(Malignant tumors)
→
is_characterized_by
→
Object:
syncytia_of_malignant_cells_with_vesicular_nuclei
(Cell morphology)
Original: Tumor#is characterized by#syncytia of malignant cells with vesicular nuclei/ conspicuous nucleoli/ and mitotic figures
#16334
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
shows
→
Object:
small_nucleoli
(Small nucleolus)
Original: Tumor cells#showed#fine granular chromatin/ nuclear size variation/ and small nucleoli
#16333
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
shows
→
Object:
nuclear_size_variation
(Nuclear size variation)
Original: Tumor cells#showed#fine granular chromatin/ nuclear size variation/ and small nucleoli
#16332
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
shows
→
Object:
fine_granular_chromatin
(Fine granular chromatin)
Original: Tumor cells#showed#fine granular chromatin/ nuclear size variation/ and small nucleoli
#16330
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
exhibits
→
Object:
prominent_nucleoli
(Prominent nucleoli)
Original: Tumor cells#exhibit#nuclear atypia/ indentations nuclei/ and prominent nucleoli
#16329
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
exhibits
→
Object:
indentation_nuclei
(Nuclear invagination)
Original: Tumor cells#exhibit#nuclear atypia/ indentations nuclei/ and prominent nucleoli
#16273
middle Confidence
Subject:
large_irregular_cells
(Tumor cells)
→
stain_positive_with
→
Object:
CD10
(Membrane Protein)
Original: Large/ irregularly shaped cells#stain positively with#Melan A/ HMB45/ S-100 protein/ SOX10/ CD10 (focally)/ and BRAF(V600E)
#16272
middle Confidence
Subject:
large_irregular_cells
(Tumor cells)
→
stain_positive_with
→
Object:
SOX10
(Transcription Factors)
Original: Large/ irregularly shaped cells#stain positively with#Melan A/ HMB45/ S-100 protein/ SOX10/ CD10 (focally)/ and BRAF(V600E)
#16271
middle Confidence
Subject:
large_irregular_cells
(Tumor cells)
→
stain_positive_with
→
Object:
S-100_protein
(Tumor marker protein)
Original: Large/ irregularly shaped cells#stain positively with#Melan A/ HMB45/ S-100 protein/ SOX10/ CD10 (focally)/ and BRAF(V600E)
#16270
middle Confidence
Subject:
large_irregular_cells
(Tumor cells)
→
stain_positive_with
→
Object:
HMB45
(Tumor marker protein)
Original: Large/ irregularly shaped cells#stain positively with#Melan A/ HMB45/ S-100 protein/ SOX10/ CD10 (focally)/ and BRAF(V600E)
#16269
middle Confidence
Subject:
large_irregular_cells
(Tumor cells)
→
stain_positive_with
→
Object:
Melan_A
(Tumor marker protein)
Original: Large/ irregularly shaped cells#stain positively with#Melan A/ HMB45/ S-100 protein/ SOX10/ CD10 (focally)/ and BRAF(V600E)
#16268
middle Confidence
Subject:
transplanted_tumor_cells
(Tumor cells)
→
stain_positive_for
→
Object:
desmin
(Cytoskeletal proteins)
Original: Transplanted tumor cells#stain positive for#vimentin/ cytokeratin/ actin/ and desmin
#16267
middle Confidence
Subject:
transplanted_tumor_cells
(Tumor cells)
→
stain_positive_for
→
Object:
actin
(Cytoskeletal proteins)
Original: Transplanted tumor cells#stain positive for#vimentin/ cytokeratin/ actin/ and desmin
#16266
middle Confidence
Subject:
transplanted_tumor_cells
(Tumor cells)
→
stain_positive_for
→
Object:
cytokeratin
(Cytoskeletal proteins)
Original: Transplanted tumor cells#stain positive for#vimentin/ cytokeratin/ actin/ and desmin
#16265
middle Confidence
Subject:
transplanted_tumor_cells
(Tumor cells)
→
stain_positive_for
→
Object:
vimentin
(Cytoskeletal proteins)
Original: Transplanted tumor cells#stain positive for#vimentin/ cytokeratin/ actin/ and desmin
#16264
middle Confidence
Subject:
histologic_transformation
(Histopathological changes)
→
is_characterized_by
→
Object:
foci_of_necrosis
(Histological characteristics)
Original: Histologic transformation in PLGA#is characterized by#a predominantly solid and cystic growth pattern/ nuclear atypia with prominent nucleoli/ and foci of necrosis
#16263
middle Confidence
Subject:
histologic_transformation
(Histopathological changes)
→
is_characterized_by
→
Object:
nuclear_atypia_with_prominent_nucleoli
(Histological characteristics)
Original: Histologic transformation in PLGA#is characterized by#a predominantly solid and cystic growth pattern/ nuclear atypia with prominent nucleoli/ and foci of necrosis
#16262
middle Confidence
Subject:
histologic_transformation
(Histopathological changes)
→
is_characterized_by
→
Object:
solid_and_cystic_growth_pattern
(Histological characteristics)
Original: Histologic transformation in PLGA#is characterized by#a predominantly solid and cystic growth pattern/ nuclear atypia with prominent nucleoli/ and foci of necrosis
#16249
middle Confidence
Subject:
NIFTP
(Tumor type)
→
is_compared_with
→
Object:
noninvasive_follicular_thyroid_neoplasm
(Tumor type)
Original: NIFTP#is compared with#C-PTC and IFV-PTC
#16248
middle Confidence
Subject:
NIFTP
(Tumor type)
→
is_compared_with
→
Object:
IFV-PTC
(Tumor type)
Original: NIFTP#is compared with#C-PTC and IFV-PTC
#16247
middle Confidence
Subject:
NIFTP
(Tumor type)
→
is_compared_with
→
Object:
C-PTC
(Tumor type)
Original: NIFTP#is compared with#C-PTC and IFV-PTC
#16241
middle Confidence
Subject:
NUTM1
(Gene)
→
is_differential_diagnosis_for
→
Object:
melanoma
(Solid Tumors)
Original: Differential diagnoses#include#basaloid carcinoma of the lung/ small cell carcinoma/ thymic carcinoma/ SMARCA4-deficient thoracic sarcoma/ other NUTM1 rearranged undifferentiated tumors/ small round cell tumors/ non-Hodgkin lymphoma/leukemia/ and melanoma
#16240
middle Confidence
Subject:
NUTM1
(Gene)
→
is_differential_diagnosis_for
→
Object:
non-Hodgkin_lymphoma_leukemia
(Solid Tumors)
Original: Differential diagnoses#include#basaloid carcinoma of the lung/ small cell carcinoma/ thymic carcinoma/ SMARCA4-deficient thoracic sarcoma/ other NUTM1 rearranged undifferentiated tumors/ small round cell tumors/ non-Hodgkin lymphoma/leukemia/ and melanoma
#16239
middle Confidence
Subject:
NUTM1
(Gene)
→
is_differential_diagnosis_for
→
Object:
small_round_cell_tumors
(Solid Tumors)
Original: Differential diagnoses#include#basaloid carcinoma of the lung/ small cell carcinoma/ thymic carcinoma/ SMARCA4-deficient thoracic sarcoma/ other NUTM1 rearranged undifferentiated tumors/ small round cell tumors/ non-Hodgkin lymphoma/leukemia/ and melanoma
#16238
middle Confidence
Subject:
NUTM1
(Gene)
→
is_differential_diagnosis_for
→
Object:
undifferentiated_tumors
(Solid Tumors)
Original: Differential diagnoses#include#basaloid carcinoma of the lung/ small cell carcinoma/ thymic carcinoma/ SMARCA4-deficient thoracic sarcoma/ other NUTM1 rearranged undifferentiated tumors/ small round cell tumors/ non-Hodgkin lymphoma/leukemia/ and melanoma
#16237
middle Confidence
Subject:
NUTM1
(Gene)
→
is_differential_diagnosis_for
→
Object:
SMARCA4-deficient_thoracic_sarcoma
(Solid Tumors)
Original: Differential diagnoses#include#basaloid carcinoma of the lung/ small cell carcinoma/ thymic carcinoma/ SMARCA4-deficient thoracic sarcoma/ other NUTM1 rearranged undifferentiated tumors/ small round cell tumors/ non-Hodgkin lymphoma/leukemia/ and melanoma
#16236
middle Confidence
Subject:
NUTM1
(Gene)
→
is_differential_diagnosis_for
→
Object:
thymic_carcinoma
(Solid Tumors)
Original: Differential diagnoses#include#basaloid carcinoma of the lung/ small cell carcinoma/ thymic carcinoma/ SMARCA4-deficient thoracic sarcoma/ other NUTM1 rearranged undifferentiated tumors/ small round cell tumors/ non-Hodgkin lymphoma/leukemia/ and melanoma
#16235
middle Confidence
Subject:
NUTM1
(Gene)
→
is_differential_diagnosis_for
→
Object:
small_cell_carcinoma
(Solid Tumors)
Original: Differential diagnoses#include#basaloid carcinoma of the lung/ small cell carcinoma/ thymic carcinoma/ SMARCA4-deficient thoracic sarcoma/ other NUTM1 rearranged undifferentiated tumors/ small round cell tumors/ non-Hodgkin lymphoma/leukemia/ and melanoma
#16234
middle Confidence
Subject:
NUTM1
(Gene)
→
is_differential_diagnosis_for
→
Object:
basaloid_carcinoma_of_the_lung
(Solid Tumors)
Original: Differential diagnoses#include#basaloid carcinoma of the lung/ small cell carcinoma/ thymic carcinoma/ SMARCA4-deficient thoracic sarcoma/ other NUTM1 rearranged undifferentiated tumors/ small round cell tumors/ non-Hodgkin lymphoma/leukemia/ and melanoma
#16087
middle Confidence
Subject:
macrocellular_carcinomas_of_lung
(Large cell lung carcinoma)
→
show
→
Object:
ultrastructural_monomorphism_of_neoplastic_cells
(Tumor cell ultrastructure)
Original: macrocellular carcinomas of lung#show#ultrastructural monomorphism of neoplastic cells
#16075
middle Confidence
Subject:
scoring_system
(Diagnostic Tools)
→
was_used_to_classify
→
Object:
cytological_grades
(Cytological grading)
Original: a scoring system#was used to classify#ductal carcinoma into cytological grades
#16074
middle Confidence
Subject:
scoring_system
(Diagnostic Tools)
→
was_used_to_classify
→
Object:
ductal_carcinoma
(Disease phenotype)
Original: a scoring system#was used to classify#ductal carcinoma into cytological grades
#16073
middle Confidence
Subject:
diagnosis_of_MCC
(Diagnostic Process)
→
requires
→
Object:
immunohistochemical_staining
(Technical conditions)
Original: Correct diagnosis of MCC#requires#adequate sampling and immunohistochemical staining
#16072
middle Confidence
Subject:
diagnosis_of_MCC
(Diagnostic Process)
→
requires
→
Object:
adequate_sampling
(Technical conditions)
Original: Correct diagnosis of MCC#requires#adequate sampling and immunohistochemical staining
#16053
middle Confidence
Subject:
Ki67
(Cell proliferation markers)
→
labeled
→
Object:
cancer_cells
(cancer cell)
Original: Ki67#labeled#over 90% of cancer cells
#16036
middle Confidence
Subject:
FNAC
(Cytological detection technology)
→
revealed
→
Object:
bi_nucleated_and_multi_nucleated_tumor_giant_cells
(Multinucleated tumor cells)
Original: FNAC#revealed#mordantly pleomorphic malignant cells predominantly plasmacytoid/ plump shaped/ prominent single to multiple nucleoli along with bi-nucleated and multi-nucleated tumor giant cells
#16035
middle Confidence
Subject:
FNAC
(Cytological detection technology)
→
revealed
→
Object:
prominent_single_to_multiple_nucleoli
(Nucleolar morphology)
Original: FNAC#revealed#mordantly pleomorphic malignant cells predominantly plasmacytoid/ plump shaped/ prominent single to multiple nucleoli along with bi-nucleated and multi-nucleated tumor giant cells
#16034
middle Confidence
Subject:
FNAC
(Cytological detection technology)
→
revealed
→
Object:
plasmacytoid_plump_shaped_cells
(Cell morphology)
Original: FNAC#revealed#mordantly pleomorphic malignant cells predominantly plasmacytoid/ plump shaped/ prominent single to multiple nucleoli along with bi-nucleated and multi-nucleated tumor giant cells
#16033
middle Confidence
Subject:
FNAC
(Cytological detection technology)
→
revealed
→
Object:
mordantly_pleomorphic_malignant_cells
(Malignant cells)
Original: FNAC#revealed#mordantly pleomorphic malignant cells predominantly plasmacytoid/ plump shaped/ prominent single to multiple nucleoli along with bi-nucleated and multi-nucleated tumor giant cells
#16022
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
shows_overexpression_of
→
Object:
DF3
(Tumor-associated antigens)
Original: Tumor cells#showed#phenotypic overexpression of the breast tumor-associated antigen DF3 compared with normal mammary epithelial cells
#15970
middle Confidence
Subject:
Immunohistochemistry
(Immunohistochemistry)
→
was_performed_for
→
Object:
CD30
(Activated T/B cell markers)
Original: Immunohistochemistry#was performed for#L26/ Alphafetoprotein/ NK1/ CD30/ and CLA
#15969
middle Confidence
Subject:
Immunohistochemistry
(Immunohistochemistry)
→
was_performed_for
→
Object:
NK1
(NK cell markers)
Original: Immunohistochemistry#was performed for#L26/ Alphafetoprotein/ NK1/ CD30/ and CLA
#15968
middle Confidence
Subject:
Immunohistochemistry
(Immunohistochemistry)
→
was_performed_for
→
Object:
L26
(B lymphocyte markers)
Original: Immunohistochemistry#was performed for#L26/ Alphafetoprotein/ NK1/ CD30/ and CLA
#15967
middle Confidence
Subject:
tumor
(Tumor)
→
is_positive_for
→
Object:
vimentin
(protein)
Original: Tumor#was positive for#vimentin
#15966
middle Confidence
Subject:
tumor
(Tumor)
→
is_negative_for
→
Object:
CD31
(protein)
Original: Tumor#was negative for#desmin/ muscle-specific actin/ estrogen/ progesterone receptors/ and CD31
#15965
middle Confidence
Subject:
tumor
(Tumor)
→
is_negative_for
→
Object:
progesterone_receptor
(protein)
Original: Tumor#was negative for#desmin/ muscle-specific actin/ estrogen/ progesterone receptors/ and CD31
#15964
middle Confidence
Subject:
tumor
(Tumor)
→
is_negative_for
→
Object:
estrogen_receptor
(protein)
Original: Tumor#was negative for#desmin/ muscle-specific actin/ estrogen/ progesterone receptors/ and CD31
#15963
middle Confidence
Subject:
tumor
(Tumor)
→
is_negative_for
→
Object:
muscle_specific_actin
(protein)
Original: Tumor#was negative for#desmin/ muscle-specific actin/ estrogen/ progesterone receptors/ and CD31
#15962
middle Confidence
Subject:
tumor
(Tumor)
→
is_negative_for
→
Object:
desmin
(protein)
Original: Tumor#was negative for#desmin/ muscle-specific actin/ estrogen/ progesterone receptors/ and CD31
#15956
middle Confidence
Subject:
Pap_smear
(Cytology)
→
reveals
→
Object:
abnormal_stromal_cells
(Stromal cells)
Original: Pap smear#revealed#endometrial necrotic debris/ abnormal endometrial glandular cells/ abnormal stromal cells
#15955
middle Confidence
Subject:
Pap_smear
(Cytology)
→
reveals
→
Object:
abnormal_endometrial_glandular_cells
(Glandular cells)
Original: Pap smear#revealed#endometrial necrotic debris/ abnormal endometrial glandular cells/ abnormal stromal cells
#15954
middle Confidence
Subject:
Pap_smear
(Cytology)
→
reveals
→
Object:
endometrial_necrotic_debris
(Necrotic fragments)
Original: Pap smear#revealed#endometrial necrotic debris/ abnormal endometrial glandular cells/ abnormal stromal cells
#15950
middle Confidence
Subject:
chest_CT
(Medical imaging technology)
→
showed
→
Object:
lymph_node_swelling
(Imaging findings)
Original: Chest computed tomography#showed#thickening and small nodules of the left pleura/ pleural effusion/ and lymph node swelling
#15949
middle Confidence
Subject:
chest_CT
(Medical imaging technology)
→
showed
→
Object:
pleural_effusion
(Imaging findings)
Original: Chest computed tomography#showed#thickening and small nodules of the left pleura/ pleural effusion/ and lymph node swelling
#15948
middle Confidence
Subject:
chest_CT
(Medical imaging technology)
→
showed
→
Object:
small_nodules_of_left_pleura
(Imaging findings)
Original: Chest computed tomography#showed#thickening and small nodules of the left pleura/ pleural effusion/ and lymph node swelling
#15947
middle Confidence
Subject:
chest_CT
(Medical imaging technology)
→
showed
→
Object:
pleural_thickening
(Imaging findings)
Original: Chest computed tomography#showed#thickening and small nodules of the left pleura/ pleural effusion/ and lymph node swelling
#15946
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
human_herpesvirus_type_8
(Virus)
Original: Tumor cells#were immunonegative for#keratin AE1/AE3/ keratin 34尾E12/ keratin 7/ keratin 20/ S100/ HMB-45/ myogenin/ desmin/ and human herpesvirus type 8
#15945
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
desmin
(Cytoskeletal proteins)
Original: Tumor cells#were immunonegative for#keratin AE1/AE3/ keratin 34尾E12/ keratin 7/ keratin 20/ S100/ HMB-45/ myogenin/ desmin/ and human herpesvirus type 8
#15944
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
myogenin
(Transcription Factors)
Original: Tumor cells#were immunonegative for#keratin AE1/AE3/ keratin 34尾E12/ keratin 7/ keratin 20/ S100/ HMB-45/ myogenin/ desmin/ and human herpesvirus type 8
#15943
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
HMB-45
(Cell markers)
Original: Tumor cells#were immunonegative for#keratin AE1/AE3/ keratin 34尾E12/ keratin 7/ keratin 20/ S100/ HMB-45/ myogenin/ desmin/ and human herpesvirus type 8
#15942
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
S100
(Cell markers)
Original: Tumor cells#were immunonegative for#keratin AE1/AE3/ keratin 34尾E12/ keratin 7/ keratin 20/ S100/ HMB-45/ myogenin/ desmin/ and human herpesvirus type 8
#15941
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
keratin_20
(Cytoskeletal proteins)
Original: Tumor cells#were immunonegative for#keratin AE1/AE3/ keratin 34尾E12/ keratin 7/ keratin 20/ S100/ HMB-45/ myogenin/ desmin/ and human herpesvirus type 8
#15940
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
keratin_7
(Cytoskeletal proteins)
Original: Tumor cells#were immunonegative for#keratin AE1/AE3/ keratin 34尾E12/ keratin 7/ keratin 20/ S100/ HMB-45/ myogenin/ desmin/ and human herpesvirus type 8
#15939
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
keratin_34βE12
(Cytoskeletal proteins)
Original: Tumor cells#were immunonegative for#keratin AE1/AE3/ keratin 34尾E12/ keratin 7/ keratin 20/ S100/ HMB-45/ myogenin/ desmin/ and human herpesvirus type 8
#15938
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
keratin_AE1/AE3
(Cytoskeletal proteins)
Original: Tumor cells#were immunonegative for#keratin AE1/AE3/ keratin 34尾E12/ keratin 7/ keratin 20/ S100/ HMB-45/ myogenin/ desmin/ and human herpesvirus type 8
#15937
middle Confidence
Subject:
AgNOR_score
(Molecular markers)
→
increases_from
→
Object:
endometrial_carcinoma
(Tumor)
Original: Mean AgNOR scores#increase from#normal to endometritis to endometrial hyperplasia and carcinoma
#15936
middle Confidence
Subject:
AgNOR_score
(Molecular markers)
→
increases_from
→
Object:
endometrial_hyperplasia
(Hyperplasia)
Original: Mean AgNOR scores#increase from#normal to endometritis to endometrial hyperplasia and carcinoma
#15935
middle Confidence
Subject:
AgNOR_score
(Molecular markers)
→
increases_from
→
Object:
Endometritis
(Inflammation)
Original: Mean AgNOR scores#increase from#normal to endometritis to endometrial hyperplasia and carcinoma
#15934
middle Confidence
Subject:
AgNOR_score
(Molecular markers)
→
increases_from
→
Object:
normal_endometrium
(Normal tissue)
Original: Mean AgNOR scores#increase from#normal to endometritis to endometrial hyperplasia and carcinoma
#15880
middle Confidence
Subject:
acute_nonlymphocytic_leukemia
(leukemia)
→
is_associated_with
→
Object:
large_AgNOR_morphology
(AgNOR Large Form)
Original: Acute nonlymphocytic leukemia#is associated with#large AgNOR morphology (blebs/complex structures)
#15879
middle Confidence
Subject:
acute_lymphoblastic_leukemia
(leukemia)
→
is_associated_with
→
Object:
small_AgNOR_morphology
(AgNOR Small Form)
Original: Acute lymphoblastic leukemia#is associated with#small AgNOR morphology (dots/chips)
#15840
middle Confidence
Subject:
AgNORs_counts
(Nucleolar organizer region-related silver stain counts)
→
are_increased_in
→
Object:
severe_gastric_mucosa_lesions
(Severe gastric mucosal lesions)
Original: Counts of AgNORs#are increased in#severe gastric mucosa lesions
#15785
middle Confidence
Subject:
TSGF
(Tumor markers)
→
was_measured_by
→
Object:
diagnostic_technique
(Diagnostic techniques)
Original: CEA/ SCC/ and TSGF#were measured by#various diagnostic techniques
#15784
middle Confidence
Subject:
SCC
(Tumor markers)
→
was_measured_by
→
Object:
diagnostic_technique
(Diagnostic techniques)
Original: CEA/ SCC/ and TSGF#were measured by#various diagnostic techniques
#15783
middle Confidence
Subject:
CEA
(Tumor markers)
→
was_measured_by
→
Object:
diagnostic_technique
(Diagnostic techniques)
Original: CEA/ SCC/ and TSGF#were measured by#various diagnostic techniques
#15735
middle Confidence
Subject:
NDP_kinase
(Kinase)
→
shows
→
Object:
negative_or_weak_immunoreactivity
(Protein expression)
Original: NDP kinase#shows#negative or weak immunoreactivity in 83% of benign or less invasive tumors
#15734
middle Confidence
Subject:
p53_gene_mutations
(Gene mutation)
→
are_useful_as
→
Object:
diagnostic_factor
(Diagnostic indicators)
Original: p53 gene mutations#are useful as#a diagnostic factor
#15733
middle Confidence
Subject:
high-grade_neoplasm
(Tumor grade)
→
shows
→
Object:
high_interphase_NOR_numbers
(NOR)
Original: high-grade neoplasms#show#high interphase NOR numbers with no increase in NOR-bearing chromosomes
#15731
middle Confidence
Subject:
AgNOR_protein_enumeration
(AgNOR Protein Count)
→
helps_differentiate
→
Object:
squamous_cell_carcinoma
(Squamous cell carcinoma)
Original: enumeration of AgNOR proteins#helps differentiate#KA from SCC
#15730
middle Confidence
Subject:
AgNOR_protein_enumeration
(AgNOR Protein Count)
→
helps_differentiate
→
Object:
keratoacanthoma
(Keratoacanthoma)
Original: enumeration of AgNOR proteins#helps differentiate#KA from SCC
#15729
middle Confidence
Subject:
proliferative_activity
(Proliferation activity)
→
is_examined_by
→
Object:
quantitative_evaluation_of_nucleolar_organizer_regions
(Nucleolar Organizer Region)
Original: proliferative activity#is examined by#quantitative evaluation of nucleolar organizer regions
#15704
middle Confidence
Subject:
percentage_of_cells_with_5+_Ag-NORs_per_nucleus
(Nuclear protein index)
→
is_useful_for
→
Object:
differentiation_between_thyroid_tumors
(Tumor phenotype)
Original: percentages with 5 or more Ag-NORs per nucleus#were useful for#differentiation between thyroid tumors
#15703
middle Confidence
Subject:
AgNOR_count
(Nuclear protein index)
→
appears_useful_for
→
Object:
assessing_differences_between_borderline_and_well-differentiated_serous_ovarian_tumors
(Tumor phenotype)
Original: AgNOR count#appears useful for#assessing differences between borderline and well-differentiated serous ovarian tumors
#15673
middle Confidence
Subject:
Ag-NOR_staining
(Silver staining technique)
→
evaluates
→
Object:
morphological_parameters_in_nucleoli
(Nucleolar morphology parameters)
Original: Ag-NOR staining technique#evaluates#morphological parameters in nucleoli
#15672
middle Confidence
Subject:
carcinomas
(cancer)
→
are_less_frequently
→
Object:
p120_negative
(p120 negative)
Original: Carcinomas#are less frequently#p120 negative
#15671
middle Confidence
Subject:
benign_hyperplasia
(Benign hyperplasia)
→
is_predominantly
→
Object:
p120_negative
(p120 negative)
Original: Benign hyperplasia#is predominantly#p120 negative
#15670
middle Confidence
Subject:
p120
(Nucleoprotein)
→
selectively_stains
→
Object:
nucleoli_of_proliferating_prostatic_epithelium
(Nucleoli of proliferative prostatic epithelial cells)
Original: P120#selectively stains#nucleoli of proliferating prostatic epithelium
#15667
middle Confidence
Subject:
silver_staining
(Dyeing technology)
→
demonstrates
→
Object:
NORs
(Nucleolar organizing region)
Original: Silver staining#demonstrates#nucleoli and NORs in breast FNA biopsies
#15666
middle Confidence
Subject:
silver_staining
(Dyeing technology)
→
demonstrates
→
Object:
nucleoli
(Nucleolus)
Original: Silver staining#demonstrates#nucleoli and NORs in breast FNA biopsies
#15656
middle Confidence
Subject:
red_pulp_expansion
(Histological changes)
→
due_to
→
Object:
lymphocytic_infiltration
(Cell infiltration)
Original: splenic enlargement#is characterized by#red pulp expansion due to lymphocytic infiltration
#15655
middle Confidence
Subject:
spindle-shaped_cells
(Cell Type)
→
show
→
Object:
elongated_nuclei
(Nuclear morphology)
Original: lesion#showed#proliferation of spindle-shaped cells with elongated nuclei arranged in interlaced fascicle pattern
#15635
middle Confidence
Subject:
irregular_narrowing_of_common_biliary_duct
(Abnormal tissue morphology)
→
was_suggestive_of
→
Object:
cholangiocarcinoma
(Malignant tumors)
Original: Irregular narrowing of the common biliary duct#was suggestive of#cholangiocarcinoma
#15619
middle Confidence
Subject:
VHL_gene_deletions
(Gene deletion)
→
were_revealed_in
→
Object:
papillary_type_2_RCC
(disease)
Original: VHL gene deletions#were revealed in#clear cell RCC and papillary type 2 RCC
#15618
middle Confidence
Subject:
VHL_gene_deletions
(Gene deletion)
→
were_revealed_in
→
Object:
clear_cell_RCC
(disease)
Original: VHL gene deletions#were revealed in#clear cell RCC and papillary type 2 RCC
#15617
middle Confidence
Subject:
multinucleate_giant_cells
(Cell Type)
→
can_be_seen_in
→
Object:
fungal_infections
(disease)
Original: Multinucleate giant cells#can be seen in#pancreatic abscesses/ fat necrosis/ pseudocysts/ tuberculosis/ sarcoidosis/ and fungal infections
#15616
middle Confidence
Subject:
multinucleate_giant_cells
(Cell Type)
→
can_be_seen_in
→
Object:
Sarcoidosis
(disease)
Original: Multinucleate giant cells#can be seen in#pancreatic abscesses/ fat necrosis/ pseudocysts/ tuberculosis/ sarcoidosis/ and fungal infections
#15615
middle Confidence
Subject:
multinucleate_giant_cells
(Cell Type)
→
can_be_seen_in
→
Object:
tuberculosis
(disease)
Original: Multinucleate giant cells#can be seen in#pancreatic abscesses/ fat necrosis/ pseudocysts/ tuberculosis/ sarcoidosis/ and fungal infections
#15614
middle Confidence
Subject:
multinucleate_giant_cells
(Cell Type)
→
can_be_seen_in
→
Object:
pseudocysts
(disease)
Original: Multinucleate giant cells#can be seen in#pancreatic abscesses/ fat necrosis/ pseudocysts/ tuberculosis/ sarcoidosis/ and fungal infections
#15613
middle Confidence
Subject:
multinucleate_giant_cells
(Cell Type)
→
can_be_seen_in
→
Object:
fat_necrosis
(disease)
Original: Multinucleate giant cells#can be seen in#pancreatic abscesses/ fat necrosis/ pseudocysts/ tuberculosis/ sarcoidosis/ and fungal infections
#15612
middle Confidence
Subject:
multinucleate_giant_cells
(Cell Type)
→
can_be_seen_in
→
Object:
pancreatic_abscesses
(disease)
Original: Multinucleate giant cells#can be seen in#pancreatic abscesses/ fat necrosis/ pseudocysts/ tuberculosis/ sarcoidosis/ and fungal infections
#15609
middle Confidence
Subject:
Adenocarcinoma
(Adenocarcinoma)
→
is_characterized_by
→
Object:
Pleomorphism
(Nuclear morphology)
Original: Adenocarcinoma#is characterized by#loss of glands with marked nuclear enlargement and pleomorphism
#15608
middle Confidence
Subject:
Adenocarcinoma
(Adenocarcinoma)
→
is_characterized_by
→
Object:
nuclear_enlargement
(Nuclear morphology)
Original: Adenocarcinoma#is characterized by#loss of glands with marked nuclear enlargement and pleomorphism
#15607
middle Confidence
Subject:
Adenocarcinoma
(Adenocarcinoma)
→
is_characterized_by
→
Object:
loss_of_glands
(Organizational form)
Original: Adenocarcinoma#is characterized by#loss of glands with marked nuclear enlargement and pleomorphism
#15604
middle Confidence
Subject:
Gnathic aggressive osteoblastoma
(Bone tumors)
→
is_distinguished_from
→
Object:
osteoblastoma-like osteosarcoma
(Osteosarcoma)
Original: Gnathic aggressive osteoblastoma#is distinguished from#osteoblastoma-like osteosarcoma
#15603
middle Confidence
Subject:
SP method
(Detection Methods)
→
is_useful_in
→
Object:
diagnosing suspicious cases
(Diagnostic Process)
Original: SP method#is useful in#diagnosing suspicious cases
#15602
middle Confidence
Subject:
Poorly differentiated synovial sarcoma
(Tumor type)
→
is_diagnosed_as
→
Object:
rhabdoid features
(Tissue morphology)
Original: Poorly differentiated SS#is diagnosed as#rhabdoid features
#15546
middle Confidence
Subject:
ETV6
(Transcription Factors)
→
shows_split_signals_in
→
Object:
nuclei
(Nucleus)
Original: A fluorescence in situ hybridization study#revealed#split signals in the nuclei in all 3 cases
#15542
middle Confidence
Subject:
tumor
(Tumor tissue)
→
expands
→
Object:
morphologic_spectrum_of_Ewing_sarcoma
(Disease phenotype)
Original: The tumor#extends#the morphologic spectrum of Ewing sarcoma beyond previously described histological variants
#15541
middle Confidence
Subject:
tumor
(Tumor)
→
shows
→
Object:
melan-A_negative_immunoprofile
(melan-A negative immunophenotype)
Original: tumors#showed#S100/SOX10-positive and HMB45/melan-A-negative immunoprofile
#15540
middle Confidence
Subject:
tumor
(Tumor)
→
shows
→
Object:
HMB45_negative_immunoprofile
(HMB45-negative immunophenotype)
Original: tumors#showed#S100/SOX10-positive and HMB45/melan-A-negative immunoprofile
#15539
middle Confidence
Subject:
tumor
(Tumor)
→
shows
→
Object:
SOX10_positive_immunoprofile
(SOX10-positive immunophenotype)
Original: tumors#showed#S100/SOX10-positive and HMB45/melan-A-negative immunoprofile
#15538
middle Confidence
Subject:
tumor
(Tumor)
→
shows
→
Object:
S100_positive_immunoprofile
(S100 positive immunophenotype)
Original: tumors#showed#S100/SOX10-positive and HMB45/melan-A-negative immunoprofile
#15533
middle Confidence
Subject:
MASC
(Tumor type)
→
is_distinguished_by
→
Object:
immunohistochemical_profile
(Molecular characteristics)
Original: MASCs#are distinguished by#specific histopathological features and immunohistochemical profile
#15532
middle Confidence
Subject:
MASC
(Tumor type)
→
is_distinguished_by
→
Object:
histopathological_feature
(Organizational characteristics)
Original: MASCs#are distinguished by#specific histopathological features and immunohistochemical profile
#15530
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Diagnostic techniques)
→
showed
→
Object:
blood_vessel
(Organizational Structure)
Original: Fine needle aspiration biopsy#showed#fragments of connective tissue with mature-appearing fat traversed by bands of fibrous collagen and vessels
#15529
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Diagnostic techniques)
→
showed
→
Object:
fibrous_collagen_band
(Organizational Structure)
Original: Fine needle aspiration biopsy#showed#fragments of connective tissue with mature-appearing fat traversed by bands of fibrous collagen and vessels
#15528
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Diagnostic techniques)
→
showed
→
Object:
mature_fat
(Cell Type)
Original: Fine needle aspiration biopsy#showed#fragments of connective tissue with mature-appearing fat traversed by bands of fibrous collagen and vessels
#15527
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Diagnostic techniques)
→
showed
→
Object:
connective_tissue_fragment
(Organizational Structure)
Original: Fine needle aspiration biopsy#showed#fragments of connective tissue with mature-appearing fat traversed by bands of fibrous collagen and vessels
#15525
middle Confidence
Subject:
Immunohistochemical_markers
(Diagnostic markers)
→
cannot_be_used_alone_for
→
Object:
screening
(Diagnostic Process)
Original: Adult intratubular germ cell neoplasia/cancer immunohistochemical markers#cannot be used alone for#screening in male infants with cryptorchidism
#15495
middle Confidence
Subject:
First_component
(Tissue composition)
→
is_positive_for
→
Object:
EMA
(Protein markers)
Original: First component#is positive for#cytokeratin AE1/AE3/ cytokeratin CAM 5.2/ and EMA
#15494
middle Confidence
Subject:
First_component
(Tissue composition)
→
is_positive_for
→
Object:
cytokeratin_CAM_5.2
(Protein markers)
Original: First component#is positive for#cytokeratin AE1/AE3/ cytokeratin CAM 5.2/ and EMA
#15493
middle Confidence
Subject:
First_component
(Tissue composition)
→
is_positive_for
→
Object:
cytokeratin_AE1/AE3
(Protein markers)
Original: First component#is positive for#cytokeratin AE1/AE3/ cytokeratin CAM 5.2/ and EMA
#15491
middle Confidence
Subject:
MGCT
(Tumor stage)
→
is_frequent_finding_in
→
Object:
testicular_tissue_adjacent_to_overt_TGCT
(organize)
Original: MGCT#is a frequent finding in#testicular tissue adjacent to overt TGCT
#15490
middle Confidence
Subject:
MGCT
(Tumor stage)
→
is_first_stage_of
→
Object:
testicular_germ_cell_tumor
(Tumor diseases)
Original: MGCT#is the first stage of malignancy in#testicular germ cell tumor (TGCT)
#15489
middle Confidence
Subject:
solitary_metastatic_focus
(Tumor metastasis)
→
present_in
→
Object:
pelvic_lymph_node
(Lymph nodes)
Original: A solitary metastatic focus#was present in#1 of 25 pelvic lymph nodes
#15473
middle Confidence
Subject:
immunohistochemical_profiles
(Immunohistochemical characteristics)
→
are_reviewed_in
→
Object:
differential_diagnosis
(Diagnostic Process)
Original: histologic findings and immunohistochemical profiles of epithelioid angiosarcoma#are reviewed in#differential diagnosis
#15472
middle Confidence
Subject:
histologic_findings
(Histological characteristics)
→
are_reviewed_in
→
Object:
differential_diagnosis
(Diagnostic Process)
Original: histologic findings and immunohistochemical profiles of epithelioid angiosarcoma#are reviewed in#differential diagnosis
#15471
middle Confidence
Subject:
obvious_vasoformative_foci
(Angiogenesis)
→
may_not_be_present_in
→
Object:
epithelioid_sarcoma
(Epithelioid sarcoma)
Original: obvious vasoformative foci#may not be present in#metastatic carcinomas/ malignant mesothelioma/ melanoma/ anaplastic lymphoma/ epithelioid peripheral nerve sheath malignancies/ and epithelioid sarcoma
#15470
middle Confidence
Subject:
obvious_vasoformative_foci
(Angiogenesis)
→
may_not_be_present_in
→
Object:
epithelioid_peripheral_nerve_sheath_malignancies
(Peripheral nerve sheath malignant tumor)
Original: obvious vasoformative foci#may not be present in#metastatic carcinomas/ malignant mesothelioma/ melanoma/ anaplastic lymphoma/ epithelioid peripheral nerve sheath malignancies/ and epithelioid sarcoma
#15469
middle Confidence
Subject:
obvious_vasoformative_foci
(Angiogenesis)
→
may_not_be_present_in
→
Object:
anaplastic_lymphoma
(Anaplastic lymphoma)
Original: obvious vasoformative foci#may not be present in#metastatic carcinomas/ malignant mesothelioma/ melanoma/ anaplastic lymphoma/ epithelioid peripheral nerve sheath malignancies/ and epithelioid sarcoma
#15468
middle Confidence
Subject:
obvious_vasoformative_foci
(Angiogenesis)
→
may_not_be_present_in
→
Object:
melanoma
(Melanoma)
Original: obvious vasoformative foci#may not be present in#metastatic carcinomas/ malignant mesothelioma/ melanoma/ anaplastic lymphoma/ epithelioid peripheral nerve sheath malignancies/ and epithelioid sarcoma
#15467
middle Confidence
Subject:
obvious_vasoformative_foci
(Angiogenesis)
→
may_not_be_present_in
→
Object:
malignant_mesothelioma
(Malignant mesothelioma)
Original: obvious vasoformative foci#may not be present in#metastatic carcinomas/ malignant mesothelioma/ melanoma/ anaplastic lymphoma/ epithelioid peripheral nerve sheath malignancies/ and epithelioid sarcoma
#15466
middle Confidence
Subject:
obvious_vasoformative_foci
(Angiogenesis)
→
may_not_be_present_in
→
Object:
metastatic_carcinoma
(Metastatic cancer)
Original: obvious vasoformative foci#may not be present in#metastatic carcinomas/ malignant mesothelioma/ melanoma/ anaplastic lymphoma/ epithelioid peripheral nerve sheath malignancies/ and epithelioid sarcoma
#15451
middle Confidence
Subject:
Breast_carcinoma
(Tumor tissue)
→
was_graded_by
→
Object:
Scarff-Bloom-Richardson_grading_system
(Diagnostic criteria)
Original: Breast carcinoma#was graded by#Robinson grading and Scarff-Bloom-Richardson grading system
#15450
middle Confidence
Subject:
Breast_carcinoma
(Tumor tissue)
→
was_graded_by
→
Object:
Robinson_grading_system
(Diagnostic criteria)
Original: Breast carcinoma#was graded by#Robinson grading and Scarff-Bloom-Richardson grading system
#15342
middle Confidence
Subject:
malignant_glands
(Malignant glands)
→
are_recognized_by
→
Object:
abnormal_location
(Pathological characteristics)
Original: malignant glands#are recognized by#abnormal size/ shape/ and location
#15341
middle Confidence
Subject:
malignant_glands
(Malignant glands)
→
are_recognized_by
→
Object:
abnormal_shape
(Pathological characteristics)
Original: malignant glands#are recognized by#abnormal size/ shape/ and location
#15340
middle Confidence
Subject:
malignant_glands
(Malignant glands)
→
are_recognized_by
→
Object:
abnormal_size
(Pathological characteristics)
Original: malignant glands#are recognized by#abnormal size/ shape/ and location
#15339
middle Confidence
Subject:
apoptotic_bodies
(apoptotic body)
→
were_seen_in
→
Object:
prostatic_adenocarcinoma
(cancer)
Original: apoptotic bodies#were seen fairly frequently in#prostatic adenocarcinoma
#15308
middle Confidence
Subject:
77-year-old_man
(Patient characteristics)
→
is_diagnosed_with
→
Object:
follicular_lymphoma_grade_3A
(Tumor diseases)
Original: A 77-year-old man#is diagnosed with#follicular lymphoma (FL)/ grade 3A
#15292
middle Confidence
Subject:
large_pale_cells
(Cell morphology)
→
interpreted_as
→
Object:
carcinoma_cells
(Tumor cells)
Original: large pale cells#were interpreted as#carcinoma cells
#15291
middle Confidence
Subject:
histologic_features
(Histological characteristics)
→
distinguish
→
Object:
benign_cells
(Normal cells)
Original: histologic features#may distinguish#carcinoma cells from benign cells
#15290
middle Confidence
Subject:
histologic_features
(Histological characteristics)
→
distinguish
→
Object:
carcinoma_cells
(Tumor cells)
Original: histologic features#may distinguish#carcinoma cells from benign cells
#15254
middle Confidence
Subject:
pathological_features
(Histological phenotype)
→
are_consistent_with
→
Object:
large_cell_variant_of_medulloblastoma
(Disease classification)
Original: pathological features#were consistent with#"large cell variant" of medulloblastoma
#15220
middle Confidence
Subject:
angiosarcoma
(Tumor)
→
is_difficult_to_diagnose_by
→
Object:
liver_FNA_biopsy
(Diagnostic techniques)
Original: Initial diagnosis#of angiosarcoma#was difficult on liver FNA biopsy
#15217
middle Confidence
Subject:
cytologic_grading_of_HCC
(Diagnostic Process)
→
is_used_as
→
Object:
adjunct_in_differential_diagnoses
(Diagnostic Process)
Original: cytologic grading of HCC#is used as#an adjunct in differential diagnoses
#15216
middle Confidence
Subject:
malignant_melanoma
(disease)
→
can_present_with
→
Object:
morphological_variants
(Disease phenotype)
Original: Malignant melanoma#can present with#various clinical manifestations and diverse morphological variants
#15215
middle Confidence
Subject:
malignant_melanoma
(disease)
→
can_present_with
→
Object:
clinical_manifestations
(Disease phenotype)
Original: Malignant melanoma#can present with#various clinical manifestations and diverse morphological variants
#15213
middle Confidence
Subject:
carcinoma_cases
(disease)
→
displayed
→
Object:
isolated_cells_with_flagrant_malignant_features
(Cell morphology phenotype)
Original: carcinoma cases#displayed#numerous isolated cells exhibiting flagrant malignant features
#15212
middle Confidence
Subject:
cytologic_differentiation_of_low_grade_dysplasia
(Diagnostic Process)
→
is_difficult
→
Object:
cytologic_differentiation_of_high_grade_dysplasia
(Diagnostic Process)
Original: cytologic differentiation of low- and high-grade dysplasia#was#difficult
#15200
middle Confidence
Subject:
MTSC
(Tumor subtype)
→
may_be_subtype_of
→
Object:
PRCC
(Tumor subtype)
Original: MTSC#may be a subtype of#PRCC
#15193
middle Confidence
Subject:
mass_biopsy
(Biopsy)
→
revealed
→
Object:
neoplastic_cells_with_abundant_cytoplasm_and_prominent_nucleoli
(Tumor cell phenotype)
Original: Mass biopsy#revealed#neoplastic cells with abundant cytoplasm and prominent nucleoli
#15188
middle Confidence
Subject:
Sj?gren's_syndrome
(disease)
→
presented_with
→
Object:
enlarged_right_parotid_gland
(Clinical symptoms)
Original: A 66-year-old woman with Sj?gren's syndrome#presented with#an enlarged right parotid gland
#15186
middle Confidence
Subject:
Fine_needle_aspiration_cytology
(Diagnostic techniques)
→
revealed
→
Object:
monomorphic_large_cells_arranged_discretely
(Cell morphology)
Original: Fine needle aspiration cytology#revealed#monomorphic large cells arranged discretely
#15182
middle Confidence
Subject:
findings
(Pathological findings)
→
are_presented_along_with
→
Object:
differential_diagnosis_of_mediastinal_neoplasm
(Differential Diagnosis)
Original: Findings#are presented along with#a differential diagnosis of mediastinal neoplasm
#15146
middle Confidence
Subject:
S-100_protein
(protein)
→
was_demonstrated_by
→
Object:
electron_microscopy
(Detection Methods)
Original: S-100 protein in undifferentiated cells#was demonstrated by#immunohistochemical and electron microscopy
#15145
middle Confidence
Subject:
S-100_protein
(protein)
→
was_demonstrated_by
→
Object:
Immunohistochemistry
(Detection Methods)
Original: S-100 protein in undifferentiated cells#was demonstrated by#immunohistochemical and electron microscopy
#15141
middle Confidence
Subject:
abnormal_imaging_findings
(Imaging features)
→
were_presented_in
→
Object:
fifth_cervical_vertebral_body
(Anatomy)
Original: Abnormal imaging findings#were presented in#the fifth cervical vertebral body
#15139
middle Confidence
Subject:
lymphoma_cases
(Patient population)
→
were_typed_using
→
Object:
large_B-cell_lymphoma
(Tumor diseases)
Original: Lymphoma cases#were typed using#REAL classification as small and large B-cell lymphoma
#15138
middle Confidence
Subject:
lymphoma_cases
(Patient population)
→
were_typed_using
→
Object:
small_B-cell_lymphoma
(Tumor diseases)
Original: Lymphoma cases#were typed using#REAL classification as small and large B-cell lymphoma
#15132
middle Confidence
Subject:
small_round_cells
(Tumor cells)
→
often_formed
→
Object:
perivascular_pseudorosettes
(Histological structure)
Original: Small round cells#often formed#perivascular pseudorosettes
#15131
middle Confidence
Subject:
mass
(Tumor phenotype)
→
consisted_of
→
Object:
small_round_cells_with_scanty_cytoplasm_and_inconspicuous_nucleoli
(Cell morphology)
Original: Histologically/ mass#consisted of#small round cells with scanty cytoplasm and inconspicuous nucleoli
#15129
middle Confidence
Subject:
S-100
(S-100 protein)
→
is_positive_marker_for
→
Object:
Immunophenotype
(Phenotype)
Original: Immunophenotype#was#CD45/ Lysozyme/ CD68 (PGMI)/ CD43/ and S-100 positive
#15128
middle Confidence
Subject:
CD43
(Leukocyte differentiation antigen)
→
is_positive_marker_for
→
Object:
Immunophenotype
(Phenotype)
Original: Immunophenotype#was#CD45/ Lysozyme/ CD68 (PGMI)/ CD43/ and S-100 positive
#15127
middle Confidence
Subject:
CD68 (PGMI)
(Leukocyte differentiation antigen)
→
is_positive_marker_for
→
Object:
Immunophenotype
(Phenotype)
Original: Immunophenotype#was#CD45/ Lysozyme/ CD68 (PGMI)/ CD43/ and S-100 positive
#15126
middle Confidence
Subject:
Lysozyme
(Lysozyme)
→
is_positive_marker_for
→
Object:
Immunophenotype
(Phenotype)
Original: Immunophenotype#was#CD45/ Lysozyme/ CD68 (PGMI)/ CD43/ and S-100 positive
#15125
middle Confidence
Subject:
CD45
(Leukocyte differentiation antigen)
→
is_positive_marker_for
→
Object:
Immunophenotype
(Phenotype)
Original: Immunophenotype#was#CD45/ Lysozyme/ CD68 (PGMI)/ CD43/ and S-100 positive
#15113
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
differentiation
→
Object:
benign_conditions
(Benign diseases)
Original: Cytologic features#differentiate#breast carcinoma from benign conditions
#15112
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
differentiation
→
Object:
breast_carcinoma
(Tumor diseases)
Original: Cytologic features#differentiate#breast carcinoma from benign conditions
#15111
middle Confidence
Subject:
FNA_findings
(Fine needle aspiration results)
→
were_correlated_with
→
Object:
pathologic_diagnosis_of_breast_biopsies
(Pathological diagnosis)
Original: Findings of FNA#were correlated with#pathologic diagnosis of breast biopsies
#15110
middle Confidence
Subject:
cytological_examination
(Cytology)
→
revealed
→
Object:
malignancy
(Disease phenotype)
Original: Cytological examination#revealed#malignancy
#15109
middle Confidence
Subject:
serologic_study
(Serological testing)
→
revealed
→
Object:
M-component_of_IgA
(Molecular markers)
Original: Serologic study#revealed#M-component of IgA
#15108
middle Confidence
Subject:
specimen_2
(Clinical specimens)
→
features
→
Object:
prominent_nucleoli
(Cell nucleolus characteristics)
Original: specimen 2#featured#a pure high-grade sarcoma with coagulative tumor cell necrosis/ mitoses/ atypical cells/ vesicular nuclei/ and prominent nucleoli
#15107
middle Confidence
Subject:
specimen_2
(Clinical specimens)
→
features
→
Object:
vesicular_nuclei
(Nuclear characteristics)
Original: specimen 2#featured#a pure high-grade sarcoma with coagulative tumor cell necrosis/ mitoses/ atypical cells/ vesicular nuclei/ and prominent nucleoli
#15106
middle Confidence
Subject:
specimen_2
(Clinical specimens)
→
features
→
Object:
atypical_cells
(Cell abnormalities)
Original: specimen 2#featured#a pure high-grade sarcoma with coagulative tumor cell necrosis/ mitoses/ atypical cells/ vesicular nuclei/ and prominent nucleoli
#15105
middle Confidence
Subject:
specimen_2
(Clinical specimens)
→
features
→
Object:
Mitoses
(Cell division phenomenon)
Original: specimen 2#featured#a pure high-grade sarcoma with coagulative tumor cell necrosis/ mitoses/ atypical cells/ vesicular nuclei/ and prominent nucleoli
#15104
middle Confidence
Subject:
specimen_2
(Clinical specimens)
→
features
→
Object:
coagulative_tumor_cell_necrosis
(Histopathological characteristics)
Original: specimen 2#featured#a pure high-grade sarcoma with coagulative tumor cell necrosis/ mitoses/ atypical cells/ vesicular nuclei/ and prominent nucleoli
#15103
middle Confidence
Subject:
specimen_2
(Clinical specimens)
→
features
→
Object:
high-grade_sarcoma
(Disease phenotype)
Original: specimen 2#featured#a pure high-grade sarcoma with coagulative tumor cell necrosis/ mitoses/ atypical cells/ vesicular nuclei/ and prominent nucleoli
#15079
middle Confidence
Subject:
cytologic_factors
(Cytological characteristics)
→
are_associated_with
→
Object:
HER2BC
(Tumor type)
Original: Cytologic factors#are associated with#tumor type
#15078
middle Confidence
Subject:
cytologic_factors
(Cytological characteristics)
→
are_associated_with
→
Object:
HRBC
(Tumor type)
Original: Cytologic factors#are associated with#tumor type
#15077
middle Confidence
Subject:
cytologic_factors
(Cytological characteristics)
→
are_associated_with
→
Object:
triple_negative_breast_cancer
(Tumor type)
Original: Cytologic factors#are associated with#tumor type
#15075
middle Confidence
Subject:
malignant_lymphomas
(Tumor type)
→
were_classified_into
→
Object:
pleomorphic_type
(Tumor subtype)
Original: malignant lymphomas#were classified into#lymphoblastic/ large cell/ and pleomorphic types
#15074
middle Confidence
Subject:
malignant_lymphomas
(Tumor type)
→
were_classified_into
→
Object:
large_cell_type
(Tumor subtype)
Original: malignant lymphomas#were classified into#lymphoblastic/ large cell/ and pleomorphic types
#15073
middle Confidence
Subject:
malignant_lymphomas
(Tumor type)
→
were_classified_into
→
Object:
lymphoblastic_type
(Tumor subtype)
Original: malignant lymphomas#were classified into#lymphoblastic/ large cell/ and pleomorphic types
#15072
middle Confidence
Subject:
histopathologic_findings
(Histopathological findings)
→
confirms
→
Object:
diagnosis_of_pilomatricoma
(Disease diagnosis)
Original: Histopathologic findings#confirmed#diagnosis of pilomatricoma
#15067
middle Confidence
Subject:
cytologic_feature
(Cytological characteristics)
→
shows_overlap_with
→
Object:
pancreatic_endocrine_tumor
(Tumor diseases)
Original: cytologic features#showed overlap#with those of pancreatic endocrine tumors
#15057
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
Revisited_for
→
Object:
diagnostic_pitfall
(Diagnostic Pitfalls)
Original: Cytologic features#reviewed for#acinar cell carcinoma and diagnostic pitfalls
#15056
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
Revisited_for
→
Object:
acinar_cell_carcinoma
(Tumor diseases)
Original: Cytologic features#reviewed for#acinar cell carcinoma and diagnostic pitfalls
#15050
middle Confidence
Subject:
AGCTs
(Tumor cell type)
→
exhibit
→
Object:
high_nuclear_cytoplasmic_ratio
(Cell morphology)
Original: AGCTs#exhibit#high nuclear:cytoplasmic ratios
#15049
middle Confidence
Subject:
basal_cell_adenoma
(Tumor type)
→
resembles
→
Object:
epithelial-rich_pleomorphic_adenoma
(Tumor type)
Original: Basal cell adenoma#resembles#epithelial-rich pleomorphic adenoma
#15030
middle Confidence
Subject:
tumor_differentiation
(Tumor differentiation characteristics)
→
influences
→
Object:
diagnostic_accuracy
(Diagnostic Accuracy)
Original: Submucosal nature of metastatic deposits and tumor differentiation#influence#diagnostic accuracy
#15029
middle Confidence
Subject:
submucosal_nature_of_metastatic_deposits
(Organizational characteristics)
→
influences
→
Object:
diagnostic_accuracy
(Diagnostic Accuracy)
Original: Submucosal nature of metastatic deposits and tumor differentiation#influence#diagnostic accuracy
#15019
middle Confidence
Subject:
cytologic_study
(Cytological analysis)
→
is_presented_for
→
Object:
pleomorphic_liposarcoma
(Tumor)
Original: A correlative cytologic and histologic study#is presented for#myxoid liposarcoma and pleomorphic liposarcoma
#15018
middle Confidence
Subject:
cytologic_study
(Cytological analysis)
→
is_presented_for
→
Object:
myxoid_liposarcoma
(Tumor)
Original: A correlative cytologic and histologic study#is presented for#myxoid liposarcoma and pleomorphic liposarcoma
#15002
middle Confidence
Subject:
2SC_negative_cases
(Molecular test results)
→
did_not_show
→
Object:
FH_gene_abnormalities
(Genetic abnormalities)
Original: 2SC-negative cases#did not show#FH gene abnormalities
#14985
middle Confidence
Subject:
fine-needle_aspiration_cytology
(Diagnostic techniques)
→
was_performed_for
→
Object:
mediastinal_germ_cell_tumor
(Tumor type)
Original: Fine-needle aspiration cytology#was performed for#unusual germ cell tumors of the mediastinum
#14958
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
PAS
(Molecular staining markers)
Original: Tumor cells#are positive for#PAS
#14950
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_negative_for
→
Object:
cytokeratin_7
(Cytoskeletal proteins)
Original: Neoplastic cells#are negative for#cytokeratin 7
#14947
middle Confidence
Subject:
diagnostic_model
(AI Models)
→
classifies
→
Object:
AC
(disease)
Original: A model#is developed to classify#cases as SCC or AC
#14946
middle Confidence
Subject:
diagnostic_model
(AI Models)
→
classifies
→
Object:
SCC
(disease)
Original: A model#is developed to classify#cases as SCC or AC
#14945
middle Confidence
Subject:
tumor_cell
(cell)
→
is_positive_for
→
Object:
S-100_protein
(Calcium Binding Protein)
Original: The cells#are positive for#vimentin and S-100 protein
#14944
middle Confidence
Subject:
tumor_cell
(cell)
→
is_positive_for
→
Object:
vimentin
(Intermediate filament protein)
Original: The cells#are positive for#vimentin and S-100 protein
#14915
middle Confidence
Subject:
Tumor-associated_fibrosis
(Tissue Microenvironment)
→
may_affect
→
Object:
fine-needle_aspiration_cytology_accuracy
(Diagnostic Accuracy)
Original: Tumor-associated fibrosis#may affect#fine-needle aspiration cytology accuracy in granular cell tumor
#14901
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
involve
→
Object:
high-grade_squamous_intraepithelial_lesions_in_endocervical_glands
(Pathological characteristics)
Original: Cytologic features#involved#high-grade squamous intraepithelial lesions in endocervical glands
#14860
middle Confidence
Subject:
Cytological_findings
(Cytological findings)
→
suggested
→
Object:
leiomyosarcoma
(Malignant tumors)
Original: Cytological findings#suggested#leiomyosarcoma but diagnosis remained uncertain due to absence of mitosis and/or necrotic substance
#14859
middle Confidence
Subject:
Uterine_cervical_smear
(Cytology)
→
revealed
→
Object:
isolated_spindle_cells
(Cell morphology)
Original: Uterine cervical smear#revealed#numerous spindle cells present in clusters or as isolated cells
#14858
middle Confidence
Subject:
Uterine_cervical_smear
(Cytology)
→
revealed
→
Object:
numerous_spindle_cells_in_clusters
(Cell morphology)
Original: Uterine cervical smear#revealed#numerous spindle cells present in clusters or as isolated cells
#14857
middle Confidence
Subject:
Adenomyoma_of_the_uterus
(Benign tumors)
→
was_difficult_to_distinguish_from
→
Object:
leiomyosarcoma
(Malignant tumors)
Original: Adenomyoma of the uterus#was difficult to distinguish from#leiomyosarcoma
#14850
middle Confidence
Subject:
Glomerulations
(Histological characteristics)
→
is_diagnostic_of
→
Object:
prostate_carcinoma
(Tumor diseases)
Original: Glomerulations#are diagnostic of#prostate carcinoma
#14849
middle Confidence
Subject:
Mucinous_fibroplasia
(Histological characteristics)
→
is_diagnostic_of
→
Object:
prostate_carcinoma
(Tumor diseases)
Original: Mucinous fibroplasia#is diagnostic of#prostate carcinoma
#14848
middle Confidence
Subject:
Perineural_invasion
(Histological characteristics)
→
is_diagnostic_of
→
Object:
prostate_carcinoma
(Tumor diseases)
Original: Perineural invasion (PNI)#is diagnostic of#prostate carcinoma
#14847
middle Confidence
Subject:
Histologic_findings
(Histological manifestations)
→
are_diagnostic_of
→
Object:
prostate_carcinoma
(Tumor diseases)
Original: Histologic findings#are diagnostic of#prostate carcinoma
#14840
middle Confidence
Subject:
Histologic_examination
(Pathological technology)
→
revealed
→
Object:
SmC
(Tumor type)
Original: Histologic examination#revealed#LCNEC with minor foci of SmCC
#14839
middle Confidence
Subject:
Uterine_endometrium_curettage
(Pathological technology)
→
revealed
→
Object:
squamous_differentiation
(Differentiation characteristics)
Original: Uterine endometrium curettage#revealed#endometrioid adenocarcinoma with squamous differentiation
#14837
middle Confidence
Subject:
gluteal_mass
(Lump)
→
detected_by
→
Object:
FNAB_findings
(Fine needle aspiration pathology)
Original: FNAB findings#reveal#a large gluteal mass in a 29-year-old female
#14836
middle Confidence
Subject:
testicular_tumor
(Testicular tumors)
→
detected_by
→
Object:
abdominal_exploration
(Imaging tests)
Original: Abdominal exploration#revealed#a large solitary liver mass/ massively enlarged retroperitoneal lymph nodes/ and a 4-cm testicular tumor
#14835
middle Confidence
Subject:
enlarged_retroperitoneal_lymph_nodes
(Swollen lymph nodes)
→
detected_by
→
Object:
abdominal_exploration
(Imaging tests)
Original: Abdominal exploration#revealed#a large solitary liver mass/ massively enlarged retroperitoneal lymph nodes/ and a 4-cm testicular tumor
#14834
middle Confidence
Subject:
large_liver_mass
(Liver mass)
→
detected_by
→
Object:
abdominal_exploration
(Imaging tests)
Original: Abdominal exploration#revealed#a large solitary liver mass/ massively enlarged retroperitoneal lymph nodes/ and a 4-cm testicular tumor
#14833
middle Confidence
Subject:
small_tight_clusters_of_cells_with_high_nuclear_cytoplasmic_ratio
(Cell morphology)
→
characterize
→
Object:
tumor
(Tumor)
Original: Tumor#consisted of#small tight clusters of cells with high nuclear/cytoplasmic ratio
#14832
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
stained_with
→
Object:
β-endorphin
(Protein markers)
Original: Tumor cells#stained with#anti-adrenocorticotropic hormone (ACTH)/ α-melanin-stimulating hormone (MSH)/ and β-endorphin antibodies
#14831
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
stained_with
→
Object:
MSH
(Protein markers)
Original: Tumor cells#stained with#anti-adrenocorticotropic hormone (ACTH)/ α-melanin-stimulating hormone (MSH)/ and β-endorphin antibodies
#14830
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
stained_with
→
Object:
ACTH
(Protein markers)
Original: Tumor cells#stained with#anti-adrenocorticotropic hormone (ACTH)/ α-melanin-stimulating hormone (MSH)/ and β-endorphin antibodies
#14829
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
was_immunonegative_for
→
Object:
thyroid_transcription_factor-1
(Protein markers)
Original: Tumor cell#expressed#calretinin and WT-1 and was immunonegative for thyroid transcription factor-1
#14828
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
expressed
→
Object:
WT-1
(Protein markers)
Original: Tumor cell#expressed#calretinin and WT-1 and was immunonegative for thyroid transcription factor-1
#14827
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
expressed
→
Object:
calretinin
(Protein markers)
Original: Tumor cell#expressed#calretinin and WT-1 and was immunonegative for thyroid transcription factor-1
#14824
middle Confidence
Subject:
pregnant_woman
(Patient characteristics)
→
presented_with
→
Object:
nipple_tumor
(Disease phenotype)
Original: 19-year-old pregnant woman#presented with#a nipple tumor
#14823
middle Confidence
Subject:
Grading_system
(Rating system)
→
is_combined_with
→
Object:
morphologic_description
(Morphological description)
Original: Grading system#is combined with#morphologic description
#14818
middle Confidence
Subject:
Multilocular_cystic_form
(Imaging findings)
→
is_the_signature_of
→
Object:
this_lesion_on_radiology
(Lesion imaging features)
Original: Multilocular cystic form#is the signature of#this lesion on radiology
#14817
middle Confidence
Subject:
Two_cases
(Case)
→
were_diagnosed_in
→
Object:
our_center_with_detailed_clinical_information
(Diagnosis Case)
Original: Two cases#were diagnosed in#our center with detailed clinical information
#14773
middle Confidence
Subject:
Cytomorphological features
(Cell morphology)
→
are_evaluated_during
→
Object:
ROSE for lung cancer diagnosis
(Diagnostic techniques)
Original: cytomorphological features#are evaluated during#ROSE for lung cancer diagnosis
#14765
middle Confidence
Subject:
Ewing_sarcomas
(Tumor type)
→
expressed
→
Object:
NKX2.2
(Transcription Factors)
Original: Ewing sarcomas#expressed#NKX2.2
#14764
middle Confidence
Subject:
CIC-rearranged_sarcomas
(Tumor type)
→
expressed
→
Object:
calretinin
(Protein markers)
Original: CIC-rearranged sarcomas#expressed#heterogeneous CD99/ nuclear WT1/ and calretinin
#14763
middle Confidence
Subject:
CIC-rearranged_sarcomas
(Tumor type)
→
expressed
→
Object:
WT1
(Protein markers)
Original: CIC-rearranged sarcomas#expressed#heterogeneous CD99/ nuclear WT1/ and calretinin
#14762
middle Confidence
Subject:
CIC-rearranged_sarcomas
(Tumor type)
→
expressed
→
Object:
CD99
(Protein markers)
Original: CIC-rearranged sarcomas#expressed#heterogeneous CD99/ nuclear WT1/ and calretinin
#14759
middle Confidence
Subject:
Fluorescence_in_situ_hybridization_findings
(FISH testing)
→
suggested
→
Object:
adenomatoid_mesothelioma
(Tumor type)
Original: Histochemical/ immunohistochemical/ and fluorescence in situ hybridization findings#suggested#adenomatoid mesothelioma
#14758
middle Confidence
Subject:
Immunohistochemical_findings
(Immunohistochemistry)
→
suggested
→
Object:
adenomatoid_mesothelioma
(Tumor type)
Original: Histochemical/ immunohistochemical/ and fluorescence in situ hybridization findings#suggested#adenomatoid mesothelioma
#14757
middle Confidence
Subject:
Histochemical_findings
(Histochemical testing)
→
suggested
→
Object:
adenomatoid_mesothelioma
(Tumor type)
Original: Histochemical/ immunohistochemical/ and fluorescence in situ hybridization findings#suggested#adenomatoid mesothelioma
#14744
middle Confidence
Subject:
fine_needle_cytology
(Cytology)
→
is_confirmed_by
→
Object:
thyroglobulin_immunoassay
(Immunoassay)
Original: Fine needle cytology#is confirmed by#Parathormone and Thyroglobulin immunoassay
#14743
middle Confidence
Subject:
fine_needle_cytology
(Cytology)
→
is_confirmed_by
→
Object:
parathormone_immunoassay
(Immunoassay)
Original: Fine needle cytology#is confirmed by#Parathormone and Thyroglobulin immunoassay
#14742
middle Confidence
Subject:
Immunophenotyping
(Molecular detection technology)
→
is_positive_for
→
Object:
CK
(Cytokeratin)
Original: immunophenotyping#is positive for#CD99/ NSE/ and CK
#14741
middle Confidence
Subject:
Immunophenotyping
(Molecular detection technology)
→
is_positive_for
→
Object:
NSE
(Enzyme markers)
Original: immunophenotyping#is positive for#CD99/ NSE/ and CK
#14740
middle Confidence
Subject:
Immunophenotyping
(Molecular detection technology)
→
is_positive_for
→
Object:
CD99
(Cell surface markers)
Original: immunophenotyping#is positive for#CD99/ NSE/ and CK
#14736
middle Confidence
Subject:
foamy_gland_carcinoma
(Tumor type)
→
is_recognized_by
→
Object:
pink_acellular_secretions
(Characteristics of secretions)
Original: foamy gland carcinoma#is recognized by#abundant foamy cytoplasm/ crowded or infiltrative glands/ and pink acellular secretions
#14735
middle Confidence
Subject:
foamy_gland_carcinoma
(Tumor type)
→
is_recognized_by
→
Object:
crowded_or_infiltrative_glands
(Glandular structure characteristics)
Original: foamy gland carcinoma#is recognized by#abundant foamy cytoplasm/ crowded or infiltrative glands/ and pink acellular secretions
#14734
middle Confidence
Subject:
foamy_gland_carcinoma
(Tumor type)
→
is_recognized_by
→
Object:
abundant_foamy_cytoplasm
(Cytoplasmic morphology)
Original: foamy gland carcinoma#is recognized by#abundant foamy cytoplasm/ crowded or infiltrative glands/ and pink acellular secretions
#14733
middle Confidence
Subject:
epithelioid_angiosarcoma
(Tumor type)
→
is_present_in
→
Object:
thyroid_gland
(organ)
Original: epithelioid angiosarcoma#is present in#thyroid gland
#14732
middle Confidence
Subject:
neoplastic_columnar_epithelium
(Tumor epithelial cells)
→
has
→
Object:
pathological_mitosis
(Mitotic abnormalities)
Original: neoplastic columnar epithelium#has#polymorphic nuclei/ irregular nuclear membrane/ large irregular nucleoli and pathological mitosis
#14731
middle Confidence
Subject:
neoplastic_columnar_epithelium
(Tumor epithelial cells)
→
has
→
Object:
large_irregular_nucleoli
(Nucleolar morphology)
Original: neoplastic columnar epithelium#has#polymorphic nuclei/ irregular nuclear membrane/ large irregular nucleoli and pathological mitosis
#14730
middle Confidence
Subject:
neoplastic_columnar_epithelium
(Tumor epithelial cells)
→
has
→
Object:
irregular_nuclear_membrane
(Nuclear membrane morphology)
Original: neoplastic columnar epithelium#has#polymorphic nuclei/ irregular nuclear membrane/ large irregular nucleoli and pathological mitosis
#14729
middle Confidence
Subject:
neoplastic_columnar_epithelium
(Tumor epithelial cells)
→
has
→
Object:
polymorphic_nuclei
(Nuclear morphology)
Original: neoplastic columnar epithelium#has#polymorphic nuclei/ irregular nuclear membrane/ large irregular nucleoli and pathological mitosis
#14639
middle Confidence
Subject:
Primary_esophageal_adenocarcinoma
(Disease phenotype)
→
diagnosed_in
→
Object:
cytologic_specimens
(Cytology specimens)
Original: Primary esophageal adenocarcinoma#was diagnosed in#15 of 18 cytologic specimens
#14638
middle Confidence
Subject:
Endopap_Endometrial_Sampler
(Diagnostic Tools)
→
used_in
→
Object:
Women
(Patient characteristics)
Original: Endopap Endometrial Sampler#was used in#1/465 women
#14601
middle Confidence
Subject:
Reddish_coalescing_flat-topped_papules_on_trunk_and_extremities
(Skin phenotype)
→
resembles
→
Object:
Papuloerythroderma
(Skin diseases)
Original: Reddish/ coalescing/ flat-topped papules on trunk and extremities#resembled#papuloerythroderma
#14600
middle Confidence
Subject:
Follicular_adenomas
(Tumor type)
→
pose
→
Object:
cytopathologic_diagnostic_problem_between_PTC
(Difficulties in diagnosis)
Original: Follicular adenomas#pose#cytopathologic diagnostic problems between nodular goiter/ follicular adenoma/ and PTC
#14599
middle Confidence
Subject:
Follicular_adenomas
(Tumor type)
→
pose
→
Object:
cytopathologic_diagnostic_problem_between_follicular_adenoma
(Difficulties in diagnosis)
Original: Follicular adenomas#pose#cytopathologic diagnostic problems between nodular goiter/ follicular adenoma/ and PTC
#14598
middle Confidence
Subject:
Follicular_adenomas
(Tumor type)
→
pose
→
Object:
cytopathologic_diagnostic_problem_between_nodular_goiter
(Difficulties in diagnosis)
Original: Follicular adenomas#pose#cytopathologic diagnostic problems between nodular goiter/ follicular adenoma/ and PTC
#14595
middle Confidence
Subject:
Nuclear_changes
(Nuclear morphology)
→
were_graded_into
→
Object:
three_levels_based_on_nuclear_enlargement_membrane_thickening_or_presence_of_grooves_pseudoinclusions
(Nuclear fractionation)
Original: Nuclear changes#were graded into#three levels based on nuclear enlargement/ membrane thickening/ or presence of grooves/pseudoinclusions
#14594
middle Confidence
Subject:
Neoplastic_non-PTC_lesions
(Tumor type)
→
lack
→
Object:
coarse_chromatin_pattern
(Cytological characteristics)
Original: Neoplastic non-PTC lesions#lacked#a coarse chromatin pattern
#14593
middle Confidence
Subject:
Neoplastic_non-PTC_lesions
(Tumor type)
→
was_identified_with
→
Object:
fine_chromatin_pattern_in_cytology
(Cytological characteristics)
Original: Low-grade PTC and neoplastic non-PTC lesions#were identified with#a fine chromatin pattern in cytology specimens
#14592
middle Confidence
Subject:
histologic_examination
(Diagnostic Methods)
→
reveals
→
Object:
markedly_enlarged_individual_keratinocytes
(Cytological characteristics)
Original: Histologic examination#revealed#epidermal maturation disturbances with scattered markedly enlarged individual keratinocytes
#14591
middle Confidence
Subject:
histologic_examination
(Diagnostic Methods)
→
reveals
→
Object:
epidermal_maturation_disturbances
(Histological characteristics)
Original: Histologic examination#revealed#epidermal maturation disturbances with scattered markedly enlarged individual keratinocytes
#14590
middle Confidence
Subject:
patient
(patient)
→
presents_with
→
Object:
soft_tissue_mass
(Clinical symptoms)
Original: Nine patients#presented with#a chief complaint of soft tissue mass with clinically suspected MO
#14589
middle Confidence
Subject:
TCV
(Tumor type)
→
shows
→
Object:
distinctive_cytologic_features
(Cytological characteristics)
Original: TCV#showed#distinctive cytologic features
#14588
middle Confidence
Subject:
UV-PTC
(Tumor type)
→
is_diagnosed_by
→
Object:
FNA_specimen
(Cytology samples)
Original: Thirty FNA specimens of histologically proven TCV#were compared with#32 FNA specimens of histologically proven UV-PTC
#14587
middle Confidence
Subject:
TCV
(Tumor type)
→
is_diagnosed_by
→
Object:
FNA_specimen
(Cytology samples)
Original: Thirty FNA specimens of histologically proven TCV#were compared with#32 FNA specimens of histologically proven UV-PTC
#14578
middle Confidence
Subject:
inconspicuous_nucleoli
(Nuclear characteristics)
→
is_a_feature_of
→
Object:
LGEMCA
(Tumor type)
Original: consistent cytomorphologic features#include#nuclear overlapping/ low to intermediate nuclear to cytoplasmic ratios/ and inconspicuous nucleoli
#14577
middle Confidence
Subject:
low_nuclear_to_cytoplasmic_ratio
(Nuclear characteristics)
→
is_a_feature_of
→
Object:
LGEMCA
(Tumor type)
Original: consistent cytomorphologic features#include#nuclear overlapping/ low to intermediate nuclear to cytoplasmic ratios/ and inconspicuous nucleoli
#14576
middle Confidence
Subject:
nuclear_overlapping
(Nuclear characteristics)
→
is_a_feature_of
→
Object:
LGEMCA
(Tumor type)
Original: consistent cytomorphologic features#include#nuclear overlapping/ low to intermediate nuclear to cytoplasmic ratios/ and inconspicuous nucleoli
#14575
middle Confidence
Subject:
metastatic_LGEMCA
(Tumor type)
→
generates
→
Object:
cellular_specimens_with_gland_formation
(Cell morphology)
Original: metastatic LGEMCAs#generate#cellular specimens composed of cohesive clusters of cells with gland formation
#14551
middle Confidence
Subject:
Cytologic_features
(Cytological characteristics)
→
must_be_assessed_to_make
→
Object:
diagnosis_of_malignancy
(Malignant tumor diagnosis)
Original: Cytologic features#must be assessed to make#the diagnosis of malignancy
#14550
middle Confidence
Subject:
Cytology
(Cytology)
→
has_sensitivity_of
→
Object:
carcinoma_detection
(Cancer Detection)
Original: Cytology#had a sensitivity of#85% for detecting in situ or invasive carcinoma
#14542
middle Confidence
Subject:
Cytologic_descriptions
(Cytological characteristics)
→
are_correlated_with
→
Object:
histologic_findings
(Histological characteristics)
Original: Cytologic descriptions#are correlated with#histologic findings
#14477
middle Confidence
Subject:
effusions_associated_with_OC
(Tumor-related effusion)
→
have
→
Object:
moderate_to_high_cellularity
(Cell density)
Original: effusions associated with OC#had#moderate to high cellularity
#14476
middle Confidence
Subject:
effusions_associated_with_OC
(Tumor-related effusion)
→
contain
→
Object:
blood
(blood components)
Original: effusions associated with OC#contained#blood
#14459
middle Confidence
Subject:
Immunohistochemistry
(Detection Technology)
→
may_be_misleading_in
→
Object:
prostate_cancer_features
(Disease phenotype)
Original: Rectal glands#are associated with#features of prostate cancer/ and immunohistochemistry may be misleading
#14458
middle Confidence
Subject:
rectal_glands
(Organizational Structure)
→
are_associated_with
→
Object:
prostate_cancer_features
(Disease phenotype)
Original: Rectal glands#are associated with#features of prostate cancer/ and immunohistochemistry may be misleading
#14457
middle Confidence
Subject:
goblet_cells
(Cell Type)
→
serves_as
→
Object:
diagnostic_clue_for_distorted_rectal_fragments
(Diagnostic clues)
Original: Diagnostic clues#to recognizing#distorted rectal fragments included lamina propria/ detached tissue/ inflammation/ goblet cells
#14456
middle Confidence
Subject:
inflammation
(Inflammation)
→
serves_as
→
Object:
diagnostic_clue_for_distorted_rectal_fragments
(Diagnostic clues)
Original: Diagnostic clues#to recognizing#distorted rectal fragments included lamina propria/ detached tissue/ inflammation/ goblet cells
#14455
middle Confidence
Subject:
detached_tissue
(Organizational Structure)
→
serves_as
→
Object:
diagnostic_clue_for_distorted_rectal_fragments
(Diagnostic clues)
Original: Diagnostic clues#to recognizing#distorted rectal fragments included lamina propria/ detached tissue/ inflammation/ goblet cells
#14454
middle Confidence
Subject:
lamina_propria
(Organizational Structure)
→
serves_as
→
Object:
diagnostic_clue_for_distorted_rectal_fragments
(Diagnostic clues)
Original: Diagnostic clues#to recognizing#distorted rectal fragments included lamina propria/ detached tissue/ inflammation/ goblet cells
#14437
middle Confidence
Subject:
nest_of_moderately_differentiated_cell
(Cell structure)
→
represented
→
Object:
metastatic_pituitary_carcinoma
(Disease phenotype)
Original: nests of moderately-differentiated cells#represent#metastatic pituitary carcinoma
#14436
middle Confidence
Subject:
mantle_cell_lymphoma_tumor
(Tumor tissue)
→
displays
→
Object:
blastoid_morphology
(Morphological characteristics)
Original: mantle cell lymphoma (MCL) tumors#have#blastoid morphology
#14351
middle Confidence
Subject:
Biopsy_under_colposcope
(Pathological diagnostic procedures)
→
confirmed
→
Object:
relapse_of_ALL
(Disease diagnosis)
Original: Biopsy under colposcope#confirmed#relapse of ALL
#14304
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
CD79a
(B cell markers)
Original: Tumor cells#were negative for#CD21/ Pan B/ and CD79a
#14303
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
Pan_B
(B cell markers)
Original: Tumor cells#were negative for#CD21/ Pan B/ and CD79a
#14302
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
CD21
(B cell markers)
Original: Tumor cells#were negative for#CD21/ Pan B/ and CD79a
#14301
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD3
(T cell markers)
Original: Tumor cells#were positive for#CD3
#14300
middle Confidence
Subject:
Pleomorphism
(Tumor Histological Characteristics)
→
is_feature_of
→
Object:
malignancy
(Disease phenotype)
Original: Features of malignancy#include#necrosis/ cellular spindling/ vesicular nuclei with large nucleoli/ increased mitotic activity/ high nuclear to cytoplasmic ratio/ and pleomorphism
#14299
middle Confidence
Subject:
high_nuclear_to_cytoplasmic_ratio
(Tumor Histological Characteristics)
→
is_feature_of
→
Object:
malignancy
(Disease phenotype)
Original: Features of malignancy#include#necrosis/ cellular spindling/ vesicular nuclei with large nucleoli/ increased mitotic activity/ high nuclear to cytoplasmic ratio/ and pleomorphism
#14298
middle Confidence
Subject:
increased_mitotic_activity
(Tumor Histological Characteristics)
→
is_feature_of
→
Object:
malignancy
(Disease phenotype)
Original: Features of malignancy#include#necrosis/ cellular spindling/ vesicular nuclei with large nucleoli/ increased mitotic activity/ high nuclear to cytoplasmic ratio/ and pleomorphism
#14297
middle Confidence
Subject:
vesicular_nuclei_with_large_nucleoli
(Tumor Histological Characteristics)
→
is_feature_of
→
Object:
malignancy
(Disease phenotype)
Original: Features of malignancy#include#necrosis/ cellular spindling/ vesicular nuclei with large nucleoli/ increased mitotic activity/ high nuclear to cytoplasmic ratio/ and pleomorphism
#14296
middle Confidence
Subject:
cellular_spindling
(Tumor Histological Characteristics)
→
is_feature_of
→
Object:
malignancy
(Disease phenotype)
Original: Features of malignancy#include#necrosis/ cellular spindling/ vesicular nuclei with large nucleoli/ increased mitotic activity/ high nuclear to cytoplasmic ratio/ and pleomorphism
#14295
middle Confidence
Subject:
Necrosis
(Tumor Histological Characteristics)
→
is_feature_of
→
Object:
malignancy
(Disease phenotype)
Original: Features of malignancy#include#necrosis/ cellular spindling/ vesicular nuclei with large nucleoli/ increased mitotic activity/ high nuclear to cytoplasmic ratio/ and pleomorphism
#14282
middle Confidence
Subject:
invasive_urothelial_carcinoma
(Tumor type)
→
displays
→
Object:
wide_spectrum_of_morphologic_and_cytologic_changes
(Morphological characteristics)
Original: Invasive urothelial carcinoma#displays#a wide spectrum of morphologic and cytologic changes
#14264
middle Confidence
Subject:
immunocytochemical_features
(Immunophenotype)
→
indicate
→
Object:
purely_epithelial_hepatoblastoma
(Tumor type)
Original: clinical/ light microscopic/ and immunocytochemical features#indicate that#primary liver neoplasm and ovarian metastases were a purely epithelial hepatoblastoma
#14263
middle Confidence
Subject:
light_microscopic_features
(Histological characteristics)
→
indicate
→
Object:
purely_epithelial_hepatoblastoma
(Tumor type)
Original: clinical/ light microscopic/ and immunocytochemical features#indicate that#primary liver neoplasm and ovarian metastases were a purely epithelial hepatoblastoma
#14262
middle Confidence
Subject:
clinical_features
(Clinical characteristics)
→
indicate
→
Object:
purely_epithelial_hepatoblastoma
(Tumor type)
Original: clinical/ light microscopic/ and immunocytochemical features#indicate that#primary liver neoplasm and ovarian metastases were a purely epithelial hepatoblastoma
#14232
middle Confidence
Subject:
patient
(patient)
→
presents_with
→
Object:
mass_in_stomach
(Clinical symptoms)
Original: Patient#presented with#decreased appetite and mass in the stomach
#14231
middle Confidence
Subject:
patient
(patient)
→
presents_with
→
Object:
decreased_appetite
(Clinical symptoms)
Original: Patient#presented with#decreased appetite and mass in the stomach
#14229
middle Confidence
Subject:
EUS-FNA
(Diagnostic techniques)
→
performed_for
→
Object:
pancreatic_tumor
(Tumor)
Original: A 72-year-old man#underwent#EUS-FNA for pancreatic tumor
#14207
middle Confidence
Subject:
classification
(Classification)
→
is_proposed_for
→
Object:
ductal_carcinoma_in_situ
(Disease phenotype)
Original: New classification#is proposed for#ductal carcinoma in situ (DCIS)
#14193
middle Confidence
Subject:
electron_microscopic_findings
(Electron microscopy results)
→
support
→
Object:
diagnosis_of_granulocytic_sarcoma
(Disease diagnosis)
Original: electron microscopic findings#supported#diagnosis of granulocytic sarcoma
#14190
middle Confidence
Subject:
FDC
(Follicular dendritic cells)
→
recognized_by
→
Object:
distinct_central_nucleolus
(Nuclear characteristics)
Original: FDC#can be recognized by#distinct central nucleolus and other features
#14188
middle Confidence
Subject:
RCC
(Renal cell carcinoma)
→
raises_diagnosis_of
→
Object:
tubulocystic_RCC
(Kidney tumor subtypes)
Original: RCC#raised diagnosis of#tubulocystic RCC
#14186
middle Confidence
Subject:
aspiration_cytology
(Cytological testing methods)
→
is_useful_for
→
Object:
diagnosis_of_hepatocellular_carcinoma_metastatic_to_nasal_cavity
(Disease diagnosis)
Original: aspiration cytology#is useful in#diagnosis and treatment of hepatocellular carcinoma metastatic to nasal cavity
#14182
middle Confidence
Subject:
primary_mandible_bone_tumor
(Tumor type)
→
exhibits
→
Object:
prominent_nucleoli
(Nuclear characteristics)
Original: primary mandible bone tumor#exhibits#monotonous epithelioid and rhabdoid cytomorphology/ vesicular chromatin/ and prominent nucleoli
#14181
middle Confidence
Subject:
primary_mandible_bone_tumor
(Tumor type)
→
exhibits
→
Object:
vesicular_chromatin
(Nuclear characteristics)
Original: primary mandible bone tumor#exhibits#monotonous epithelioid and rhabdoid cytomorphology/ vesicular chromatin/ and prominent nucleoli
#14180
middle Confidence
Subject:
primary_mandible_bone_tumor
(Tumor type)
→
exhibits
→
Object:
monotonous_epithelioid_and_rhabdoid_cytomorphology
(Cell morphology)
Original: primary mandible bone tumor#exhibits#monotonous epithelioid and rhabdoid cytomorphology/ vesicular chromatin/ and prominent nucleoli
#14179
middle Confidence
Subject:
UEA
(Tumor type)
→
showed
→
Object:
nuclear_hyperchromasia
(Nuclear characteristics)
Original: UEA#showed#three-dimensional cellular clusters/ peripheral nuclear feathering/ and nuclear hyperchromasia
#14178
middle Confidence
Subject:
UEA
(Tumor type)
→
showed
→
Object:
peripheral_nuclear_feathering
(Nuclear characteristics)
Original: UEA#showed#three-dimensional cellular clusters/ peripheral nuclear feathering/ and nuclear hyperchromasia
#14177
middle Confidence
Subject:
UEA
(Tumor type)
→
showed
→
Object:
three_dimensional_cellular_clusters
(Cell structure characteristics)
Original: UEA#showed#three-dimensional cellular clusters/ peripheral nuclear feathering/ and nuclear hyperchromasia
#14176
middle Confidence
Subject:
cytological_samples_of_GEA
(Cytology samples)
→
exhibited
→
Object:
vacuolated_cytoplasm
(Cytoplasmic characteristics)
Original: cytological samples of GEA#exhibited#flat/ honeycomb-like cellular sheets/ vesicular nuclei with prominent nucleoli/ and vacuolated cytoplasm
#14175
middle Confidence
Subject:
cytological_samples_of_GEA
(Cytology samples)
→
exhibited
→
Object:
vesicular_nuclei_with_prominent_nucleoli
(Nuclear characteristics)
Original: cytological samples of GEA#exhibited#flat/ honeycomb-like cellular sheets/ vesicular nuclei with prominent nucleoli/ and vacuolated cytoplasm
#14174
middle Confidence
Subject:
cytological_samples_of_GEA
(Cytology samples)
→
exhibited
→
Object:
flat_honeycomb_like_cellular_sheets
(Cell structure characteristics)
Original: cytological samples of GEA#exhibited#flat/ honeycomb-like cellular sheets/ vesicular nuclei with prominent nucleoli/ and vacuolated cytoplasm
#14173
middle Confidence
Subject:
gastric-type_endocervical_adenocarcinoma
(Tumor type)
→
is
→
Object:
distinct_histological_type_of_gynecological_malignancy
(Disease classification)
Original: gastric-type endocervical adenocarcinoma (GEA)#is#a rare but distinct histological type of gynecological malignancy
#14168
middle Confidence
Subject:
endothelial_cells
(Endothelial cells)
→
show_positive_for
→
Object:
Factor_VIII-related_antigen
(Diagnostic markers)
Original: Immunohistochemical staining#yielded#positive results for Factor VIII-related antigen
#14167
middle Confidence
Subject:
H-FLAC
(Tumor subtype)
→
shows
→
Object:
overexpression_of_p53_protein
(Protein expression)
Original: H-FLAC#was distinguished from#L-FLAC by disorganized glands/ large vesicular nuclei/ prominent nucleoli/ and overexpression of p53 protein
#14166
middle Confidence
Subject:
H-FLAC
(Tumor subtype)
→
is_distinguished_from
→
Object:
L-FLAC
(Tumor subtype)
Original: H-FLAC#was distinguished from#L-FLAC by disorganized glands/ large vesicular nuclei/ prominent nucleoli/ and overexpression of p53 protein
#14152
middle Confidence
Subject:
tumor
(Tumor)
→
consists_of
→
Object:
epithelioid_cells
(Cell morphology)
Original: Tumor#consisted of#epithelioid cells ranging from medium-sized polygonal to giant cells with prominent nucleoli
#14151
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibited
→
Object:
weak_cytoplasmic_staining_for_S-100_protein
(Protein expression)
Original: Tumor cells#exhibited#weak cytoplasmic staining for S-100 protein
#14150
middle Confidence
Subject:
encapsulated_follicular_neoplasm
(Tumor)
→
consists_of
→
Object:
polygonal_cells
(Cell morphology)
Original: Encapsulated follicular neoplasm#consisted of#spindle-like to polygonal cells with elongated to round-shaped nuclei and prominent nucleoli
#14149
middle Confidence
Subject:
encapsulated_follicular_neoplasm
(Tumor)
→
consists_of
→
Object:
spindle-like_cells
(Cell morphology)
Original: Encapsulated follicular neoplasm#consisted of#spindle-like to polygonal cells with elongated to round-shaped nuclei and prominent nucleoli
#14136
middle Confidence
Subject:
Primary_pancreatic_lymphomas
(Tumor diseases)
→
differential_diagnosis_includes
→
Object:
florid_chronic_pancreatitis
(Inflammatory diseases)
Original: Differential diagnoses of primary pancreatic lymphomas#include#secondary lymphoma/ pancreatic endocrine neoplasm/ and florid chronic pancreatitis
#14135
middle Confidence
Subject:
Primary_pancreatic_lymphomas
(Tumor diseases)
→
differential_diagnosis_includes
→
Object:
pancreatic_endocrine_neoplasm
(Tumor diseases)
Original: Differential diagnoses of primary pancreatic lymphomas#include#secondary lymphoma/ pancreatic endocrine neoplasm/ and florid chronic pancreatitis
#14134
middle Confidence
Subject:
Primary_pancreatic_lymphomas
(Tumor diseases)
→
differential_diagnosis_includes
→
Object:
secondary_lymphoma
(Tumor diseases)
Original: Differential diagnoses of primary pancreatic lymphomas#include#secondary lymphoma/ pancreatic endocrine neoplasm/ and florid chronic pancreatitis
#14127
middle Confidence
Subject:
overcall_of_suspicious_cases
(Diagnostic Phenomenon)
→
was_attributed_to
→
Object:
pinpoint_nucleoli
(Nucleolus)
Original: Overcall of suspicious cases#was attributed to#pseudopapillae/ syncytial sheets/ nuclear grooves/ and pinpoint nucleoli
#14126
middle Confidence
Subject:
overcall_of_suspicious_cases
(Diagnostic Phenomenon)
→
was_attributed_to
→
Object:
nuclear_grooves
(Nuclear structure)
Original: Overcall of suspicious cases#was attributed to#pseudopapillae/ syncytial sheets/ nuclear grooves/ and pinpoint nucleoli
#14125
middle Confidence
Subject:
overcall_of_suspicious_cases
(Diagnostic Phenomenon)
→
was_attributed_to
→
Object:
pseudopapillae
(Organizational Structure)
Original: Overcall of suspicious cases#was attributed to#pseudopapillae/ syncytial sheets/ nuclear grooves/ and pinpoint nucleoli
#14124
middle Confidence
Subject:
Morphological_analysis
(Morphological analysis)
→
was_performed_on
→
Object:
histology
(Technology Platform)
Original: Morphological analysis#was performed on#imprint cytology and histology in yolk sac tumor patients
#14123
middle Confidence
Subject:
Morphological_analysis
(Morphological analysis)
→
was_performed_on
→
Object:
imprint_cytology
(Technology Platform)
Original: Morphological analysis#was performed on#imprint cytology and histology in yolk sac tumor patients
#14119
middle Confidence
Subject:
computed_tomography
(Imaging Technology)
→
revealed
→
Object:
multiple_ossification_foci
(Imaging findings)
Original: computed tomography#revealed#multiple ossification foci within the lesion
#14095
middle Confidence
Subject:
apocrine_carcinomas_of_the_breast
(Breast cancer)
→
are_characterized_by
→
Object:
cells_with_abundant_eosinophilic_cytoplasm_and_nuclei_with_often_prominent_nucleoli
(Cell morphology)
Original: apocrine carcinomas of the breast#are characterized by#cells with abundant eosinophilic cytoplasm and nuclei with often prominent nucleoli
#14065
middle Confidence
Subject:
morphologic_criteria
(Morphological criteria)
→
distinguishes
→
Object:
SCA
(Tumor type)
Original: morphologic criteria#distinguish#reactive mesothelial cells/ SBT/ and SCA
#14064
middle Confidence
Subject:
morphologic_criteria
(Morphological criteria)
→
distinguishes
→
Object:
SBT
(Tumor type)
Original: morphologic criteria#distinguish#reactive mesothelial cells/ SBT/ and SCA
#14063
middle Confidence
Subject:
morphologic_criteria
(Morphological criteria)
→
distinguishes
→
Object:
reactive_mesothelial_cells
(Cell Type)
Original: morphologic criteria#distinguish#reactive mesothelial cells/ SBT/ and SCA
#14049
middle Confidence
Subject:
Lip_biopsy
(Biopsy specimen)
→
reveals
→
Object:
acinar-like_arrangement_of_epithelioid_cells
(Epithelial cells arranged in acinar pattern)
Original: Lip biopsy#revealed#tubulo-glandular and acinar-like arrangements of epithelioid cells
#14048
middle Confidence
Subject:
Lip_biopsy
(Biopsy specimen)
→
reveals
→
Object:
tubulo-glandular_arrangement_of_epithelioid_cells
(Tubular glands lined with epithelial cells)
Original: Lip biopsy#revealed#tubulo-glandular and acinar-like arrangements of epithelioid cells
#14041
middle Confidence
Subject:
chromocentres
(Nuclear structure)
→
aids_in
→
Object:
diagnosis_of_follicular_carcinoma
(Disease diagnosis)
Original: Increased nuclear size/ nucleoli/ and chromocentres#aid in#diagnosis of follicular carcinoma
#14040
middle Confidence
Subject:
nucleoli
(Nuclear structure)
→
aids_in
→
Object:
diagnosis_of_follicular_carcinoma
(Disease diagnosis)
Original: Increased nuclear size/ nucleoli/ and chromocentres#aid in#diagnosis of follicular carcinoma
#14039
middle Confidence
Subject:
increased_nuclear_size
(Nuclear morphology)
→
aids_in
→
Object:
diagnosis_of_follicular_carcinoma
(Disease diagnosis)
Original: Increased nuclear size/ nucleoli/ and chromocentres#aid in#diagnosis of follicular carcinoma
#14019
middle Confidence
Subject:
Immunohistochemical_study
(Diagnostic Methods)
→
supports
→
Object:
Hepatic_YST_diagnosis
(Diagnosis conclusion)
Original: Diagnosis of hepatic YST#was made by#cytologic/ histologic/ and immunohistochemical studies
#14018
middle Confidence
Subject:
CAM_5.2
(Cytokeratin)
→
supports
→
Object:
YST_diagnosis
(Diagnosis conclusion)
Original: Alpha-fetoprotein/ cytokeratin AE1/AE3/ and CAM 5.2#are#useful in supporting the diagnosis
#14017
middle Confidence
Subject:
Cytokeratin_AE1/AE3
(Cytokeratin)
→
supports
→
Object:
YST_diagnosis
(Diagnosis conclusion)
Original: Alpha-fetoprotein/ cytokeratin AE1/AE3/ and CAM 5.2#are#useful in supporting the diagnosis
#14016
middle Confidence
Subject:
Alpha-fetoprotein
(Tumor markers)
→
supports
→
Object:
YST_diagnosis
(Diagnosis conclusion)
Original: Alpha-fetoprotein/ cytokeratin AE1/AE3/ and CAM 5.2#are#useful in supporting the diagnosis
#13974
middle Confidence
Subject:
case
(Case)
→
classified_as
→
Object:
leiomyosarcoma
(Tumor subtype)
Original: cases#classified as#49 leiomyoma/ 51 leiomyosarcoma/ and 2 leiomyoblastoma
#13973
middle Confidence
Subject:
case
(Case)
→
classified_as
→
Object:
leiomyoma
(Tumor subtype)
Original: cases#classified as#49 leiomyoma/ 51 leiomyosarcoma/ and 2 leiomyoblastoma
#13972
middle Confidence
Subject:
low_grade_TC
(Tumor type)
→
is_distinguished_from
→
Object:
carcinoma
(Tumor type)
Original: low-grade TC#distinguished from#ACT/ SCLC/ or carcinoma by nuclear features/ chromatin patterns/ and nucleoli
#13971
middle Confidence
Subject:
low_grade_TC
(Tumor type)
→
is_distinguished_from
→
Object:
SCLC
(Tumor type)
Original: low-grade TC#distinguished from#ACT/ SCLC/ or carcinoma by nuclear features/ chromatin patterns/ and nucleoli
#13970
middle Confidence
Subject:
low_grade_TC
(Tumor type)
→
is_distinguished_from
→
Object:
ACT
(Tumor type)
Original: low-grade TC#distinguished from#ACT/ SCLC/ or carcinoma by nuclear features/ chromatin patterns/ and nucleoli
#13890
middle Confidence
Subject:
pulmonary_mass
(Tumor type)
→
contains
→
Object:
abundant_eosinophilic_cytoplasm
(Cell morphology)
Original: Computed tomography#revealed#a pulmonary mass with vacuolar tumor cells and abundant eosinophilic cytoplasm
#13889
middle Confidence
Subject:
pulmonary_mass
(Tumor type)
→
contains
→
Object:
vacuolar_tumor_cells
(Cell Type)
Original: Computed tomography#revealed#a pulmonary mass with vacuolar tumor cells and abundant eosinophilic cytoplasm
#13882
middle Confidence
Subject:
study
(Research)
→
established
→
Object:
cytological_features_of_giant_cell_carcinoma
(Cytological characteristics)
Original: study#established#cytological features of pulmonary pleomorphic carcinoma and giant cell carcinoma
#13881
middle Confidence
Subject:
study
(Research)
→
established
→
Object:
cytological_features_of_pulmonary_pleomorphic_carcinoma
(Cytological characteristics)
Original: study#established#cytological features of pulmonary pleomorphic carcinoma and giant cell carcinoma
#13784
middle Confidence
Subject:
papanicolaou-stained_smears
(Pathological staining samples)
→
exhibits
→
Object:
cytoplasmic_vacuolization
(Cell morphology)
Original: Papanicolaou-stained smears#exhibited#conspicuous nucleoli/ multinucleation/ and cytoplasmic vacuolization
#13783
middle Confidence
Subject:
papanicolaou-stained_smears
(Pathological staining samples)
→
exhibits
→
Object:
multinucleation
(Cell morphology)
Original: Papanicolaou-stained smears#exhibited#conspicuous nucleoli/ multinucleation/ and cytoplasmic vacuolization
#13782
middle Confidence
Subject:
papanicolaou-stained_smears
(Pathological staining samples)
→
exhibits
→
Object:
conspicuous_nucleoli
(Cell morphology)
Original: Papanicolaou-stained smears#exhibited#conspicuous nucleoli/ multinucleation/ and cytoplasmic vacuolization
#13781
middle Confidence
Subject:
cytologic_appearance_of_PM
(Cytological phenotype)
→
allows
→
Object:
exclusion_of_malignancy
(Disease phenotype)
Original: The cytologic appearance of PM#allows#exclusion of malignancy
#13780
middle Confidence
Subject:
diagnosis_of_CIN2
(Clinical diagnosis)
→
is_associated_with
→
Object:
high_grade_squamous_intraepithelial_lesions
(Disease phenotype)
Original: Diagnosis of CIN2#is associated with#high-grade squamous intraepithelial lesions
#13737
middle Confidence
Subject:
cytological_criteria
(Diagnostic criteria)
→
are_based_on
→
Object:
nuclear_staining_variation
(Cell morphological characteristics)
Original: cytological criteria#are based on#nuclear size/ chromatin dispersion/ prominence of nucleoli/ hyperchromasia/ and nuclear staining variation
#13736
middle Confidence
Subject:
cytological_criteria
(Diagnostic criteria)
→
are_based_on
→
Object:
hyperchromasia
(Cell morphological characteristics)
Original: cytological criteria#are based on#nuclear size/ chromatin dispersion/ prominence of nucleoli/ hyperchromasia/ and nuclear staining variation
#13735
middle Confidence
Subject:
cytological_criteria
(Diagnostic criteria)
→
are_based_on
→
Object:
prominence_of_nucleoli
(Cell morphological characteristics)
Original: cytological criteria#are based on#nuclear size/ chromatin dispersion/ prominence of nucleoli/ hyperchromasia/ and nuclear staining variation
#13734
middle Confidence
Subject:
cytological_criteria
(Diagnostic criteria)
→
are_based_on
→
Object:
chromatin_dispersion
(Cell morphological characteristics)
Original: cytological criteria#are based on#nuclear size/ chromatin dispersion/ prominence of nucleoli/ hyperchromasia/ and nuclear staining variation
#13733
middle Confidence
Subject:
cytological_criteria
(Diagnostic criteria)
→
are_based_on
→
Object:
nuclear_size
(Cell morphological characteristics)
Original: cytological criteria#are based on#nuclear size/ chromatin dispersion/ prominence of nucleoli/ hyperchromasia/ and nuclear staining variation
#13717
middle Confidence
Subject:
Needle_core_biopsy
(Histological procedures)
→
revealed
→
Object:
pleomorphic_neoplastic_cells
(Tumor cells)
Original: Needle core biopsy#revealed#pleomorphic neoplastic cells
#13716
middle Confidence
Subject:
Cytologic_criteria
(Diagnostic criteria)
→
helped_identify
→
Object:
features_significant_for_pleomorphic_spindle_cell_neoplasms
(Diagnosis-related features)
Original: Cytologic criteria#helped identify#features significant for pleomorphic spindle cell neoplasms
#13715
middle Confidence
Subject:
standardized_model
(Diagnostic Model)
→
is_used_for
→
Object:
diagnosis_of_cervical_carcinoma_in_situ
(Diagnostic behavior)
Original: standardized model#is used for#diagnosing cervical carcinoma in situ
#13679
middle Confidence
Subject:
BLBC
(Breast cancer molecular subtypes)
→
is_evaluated_for
→
Object:
nucleolar_appearance
(Cell nucleolus characteristics)
Original: BLBC#is evaluated for#cytomorphological features including nucleolar appearance
#13678
middle Confidence
Subject:
BLBC
(Breast cancer molecular subtypes)
→
is_evaluated_for
→
Object:
cytomorphological_features
(Cell morphology)
Original: BLBC#is evaluated for#cytomorphological features including nucleolar appearance
#13603
middle Confidence
Subject:
peripheral_neuroblastic_tumors
(Tumor type)
→
qualified_as
→
Object:
large_cell_neuroblastoma
(Tumor type)
Original: 7 out of 92 peripheral neuroblastic tumors#qualified as#large cell neuroblastomas
#13567
middle Confidence
Subject:
cyto-pattern
(Cytological morphological characteristics)
→
correlates_with
→
Object:
histological_pattern
(Histological features)
Original: cyto-patterns#correlated with#histological patterns and outcomes
#13566
middle Confidence
Subject:
primary_FNA
(Cytological sampling techniques)
→
is_used_for
→
Object:
diagnosis_of_pseudosarcomas
(Disease diagnosis)
Original: primary FNA#is used for#diagnosis of pseudosarcomas with clinical follow-up
#13497
middle Confidence
Subject:
needle_aspiration_cytology
(Diagnostic techniques)
→
is_reviewed_in
→
Object:
malignant_lymphoma_of_the_thyroid
(Malignant tumors)
Original: needle aspiration cytology#is reviewed in#five cases of malignant lymphoma of the thyroid
#13496
middle Confidence
Subject:
variant_of_atrophy
(Pathological changes)
→
is_frequently_confused_with
→
Object:
well_differentiated_adenocarcinoma_of_prostate
(Tumor tissue)
Original: variant of atrophy#is frequently confused with#well-differentiated adenocarcinoma of the prostate
#13474
middle Confidence
Subject:
tumor
(Tumor tissue)
→
shows
→
Object:
large_areas_of_chondroid_metaplasia
(Histological characteristics)
Original: tumor#showed#large areas of chondroid metaplasia
#13473
middle Confidence
Subject:
tumors
(Tumor tissue)
→
consist_of
→
Object:
sheets_of_large_atypical_cells_with_multilobated_nuclei_and_prominent_nucleoli
(Cell morphology)
Original: tumors#consisted of#sheets of large atypical cells with multilobated nuclei and prominent nucleoli
#13432
middle Confidence
Subject:
cellular_atypism
(Cellular atypia)
→
is_basis_for
→
Object:
diagnosis_of_malignancy
(Malignant tumor diagnosis)
Original: Malignancy#was diagnosed based on#cellular atypism
#13422
middle Confidence
Subject:
diagnosis_of_CNS_metastases
(Diagnosis conclusion)
→
has_been_determined_by
→
Object:
histologic_methods
(Histological detection technology)
Original: Diagnosis of central nervous system metastases#has been determined#by histologic methods
#13421
middle Confidence
Subject:
transrectal_FNA_of_prostate
(Cytological detection technology)
→
produced
→
Object:
samples_with_malignant_cells
(Tumor cell samples)
Original: Transrectal FNA of the prostate#produced#samples including malignant cells
#13387
middle Confidence
Subject:
immunohistochemical_study
(Detection Technology)
→
demonstrated
→
Object:
loss_of_myoepithelial_differentiation
(Differentiation phenotype)
Original: Immunohistochemical study#demonstrated#loss of myoepithelial differentiation/ overexpression of p53/ and high proliferative index by Ki-67
#13386
middle Confidence
Subject:
high-grade_carcinoma_cells
(Tumor cells)
→
show
→
Object:
active_mitosis
(Cellular Processes)
Original: high-grade carcinoma cells#showed#increased nuclear-cytoplasmic ratio/ prominent eosinophilic nucleoli/ and active mitosis
#13374
middle Confidence
Subject:
fine-needle_aspiration_biopsy
(Histological diagnosis)
→
showed
→
Object:
psammoma_bodies
(Organizational Structure)
Original: fine-needle aspiration biopsy#showed#epithelial cells with wide cytoplasm and psammoma bodies
#13373
middle Confidence
Subject:
fine-needle_aspiration_biopsy
(Histological diagnosis)
→
showed
→
Object:
epithelial_cells_with_wide_cytoplasm
(Cell morphology)
Original: fine-needle aspiration biopsy#showed#epithelial cells with wide cytoplasm and psammoma bodies
#13369
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_positive_for
→
Object:
neuron-specific_enolase
(Neuron-specific enzyme)
Original: tumor cells#were positive for#neuron-specific enolase
#13365
middle Confidence
Subject:
fine_needle_aspiration_cytology
(Diagnostic techniques)
→
diagnoses
→
Object:
small_cell_neuroendocrine_carcinoma_of_the_breast
(Disease name)
Original: fine-needle aspiration cytology#diagnoses#small cell neuroendocrine carcinoma of the breast
#13363
middle Confidence
Subject:
histopathologic_examination
(Pathological examination)
→
identifies
→
Object:
DFSP
(Tumor)
Original: histopathologic examination#identifies#DFSP
#13310
middle Confidence
Subject:
primary_mediastinal_seminoma
(Tumor tissue)
→
assessed_for
→
Object:
chromosome_12p_abnormalities
(Genetic variation)
Original: Primary mediastinal seminoma#was assessed for#chromosome 12p abnormalities
#13247
middle Confidence
Subject:
Cytologic_smears
(Cytology smear)
→
were_rescrutinized_to_establish
→
Object:
criteria_for_recurrence_of_tumor
(Diagnostic criteria)
Original: Cytologic smears#were rescrutinized to establish#criteria for recurrence of tumor
#13245
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
contain
→
Object:
irregular_round-shaped_nuclei_with_prominent_nucleoli_and_eosinophilic_granular_cytoplasm
(Nuclear morphology)
Original: Tumor cells#contained#irregular round-shaped nuclei with prominent nucleoli and eosinophilic granular cytoplasm
#13244
middle Confidence
Subject:
clinical_features
(Clinical manifestations)
→
need_to_be_distinguished_from
→
Object:
malignant_tumors
(Tumor type)
Original: Clinical features#need to be#distinguished from benign diseases or other malignant tumors
#13235
middle Confidence
Subject:
PCNA_stained_nuclei_percentage
(Cell proliferation markers)
→
showed
→
Object:
upregulated_in_carcinoma_group
(Disease phenotype)
Original: AgNOR parameters and PCNA-stained nuclei percentage#showed#highest values in carcinoma group
#13234
middle Confidence
Subject:
AgNOR_parameters
(Molecular markers)
→
showed
→
Object:
upregulated_in_carcinoma_group
(Disease phenotype)
Original: AgNOR parameters and PCNA-stained nuclei percentage#showed#highest values in carcinoma group
#13208
middle Confidence
Subject:
Tumor
(Tumor diseases)
→
shows
→
Object:
pedunculated_polyp_with_thin_stalk
(Tumor morphological characteristics)
Original: Tumors#were#pedunculated polyps with thin stalks
#13206
middle Confidence
Subject:
patients
(patient)
→
presented_with
→
Object:
painless_thyroid_mass
(Clinical symptoms)
Original: Patients#presented with#painless thyroid mass
#13205
middle Confidence
Subject:
Isochromosome_12p
(Chromosomal abnormalities)
→
is_helpful_for
→
Object:
diagnosis
(Diagnostic behavior)
Original: Isochromosome 12p#can be helpful for#diagnosis
#13197
middle Confidence
Subject:
T-CLL_peripheral_blood_specimen
(Clinical samples)
→
shows
→
Object:
small_mature_lymphocytes_with_irregular_nuclear_margin
(Cell morphology)
Original: T-CLL peripheral blood specimen#showed#small lymphocytes with mature appearance and irregular nuclear margin
#13185
middle Confidence
Subject:
Metastatic_epithelioid_hemangioendothelioma
(Tumor type)
→
was_diagnosed_in
→
Object:
pleural_effusion
(Disease manifestations)
Original: Metastatic epithelioid hemangioendothelioma#was diagnosed in#a pleural effusion
#13184
middle Confidence
Subject:
Fine-needle_aspiration
(Detection Technology)
→
revealed
→
Object:
plasmacytoid_cells
(Cell Type)
Original: Fine-needle aspiration#revealed#epithelioid and plasmacytoid cells with elongated nuclei and fine chromatin
#13183
middle Confidence
Subject:
Fine-needle_aspiration
(Detection Technology)
→
revealed
→
Object:
epithelioid_cells
(Cell Type)
Original: Fine-needle aspiration#revealed#epithelioid and plasmacytoid cells with elongated nuclei and fine chromatin
#13182
middle Confidence
Subject:
FNA_cytology
(Detection Technology)
→
revealed
→
Object:
plasmacytoid_cells
(Cell Type)
Original: FNA cytology#revealed#plasmacytoid cells with nucleoli/ intranuclear inclusions/ and mitotic figures
#13181
middle Confidence
Subject:
interdigitating_cell_processes
(Cellular substructure)
→
is_demonstrated_by
→
Object:
ultrastructural_analysis
(Detection Technology)
Original: Diagnosis#was confirmed by#immunoreactivity with CD21 and CD35 and ultrastructural demonstration of interdigitating cell processes
#13180
middle Confidence
Subject:
CD35
(Membrane receptor protein)
→
is_detected_by
→
Object:
immunoreactivity
(Detection Technology)
Original: Diagnosis#was confirmed by#immunoreactivity with CD21 and CD35 and ultrastructural demonstration of interdigitating cell processes
#13179
middle Confidence
Subject:
CD21
(Membrane receptor protein)
→
is_detected_by
→
Object:
immunoreactivity
(Detection Technology)
Original: Diagnosis#was confirmed by#immunoreactivity with CD21 and CD35 and ultrastructural demonstration of interdigitating cell processes
#13124
middle Confidence
Subject:
NRG1_rearrangement
(Gene rearrangement)
→
is_present_in
→
Object:
sarcoma
(Tumor)
Original: NRG1 rearrangements#are present in#sarcomas
#13123
middle Confidence
Subject:
distinct_cytomorphology
(Cell morphology)
→
resembles
→
Object:
primary_tumor_histologic_features
(Histological characteristics)
Original: Metastatic tumors in CSF#demonstrated#distinct cytomorphology reminiscent of primary tumor histologic features
#13122
middle Confidence
Subject:
metastatic_tumor_cell
(Tumor cells)
→
shows
→
Object:
distinct_cytomorphology
(Cell morphology)
Original: Metastatic tumors in CSF#demonstrated#distinct cytomorphology reminiscent of primary tumor histologic features
#13116
middle Confidence
Subject:
clear-cell_sarcoma
(Tumor type)
→
is_a
→
Object:
homogeneous_entity_among_soft_tissue_sarcomas
(Tumor subtype)
Original: Clear-cell sarcoma#is a#homogeneous entity among soft tissue sarcomas
#13105
middle Confidence
Subject:
Basaloid_cells
(Tumor cells)
→
contain
→
Object:
intermediate_cells
(Cell morphology)
Original: Basaloid cells#have#central areas of eosinophilic ghost shadow cells and intermediate cells
#13104
middle Confidence
Subject:
Basaloid_cells
(Tumor cells)
→
contain
→
Object:
central_eosinophilic_ghost_shadow_cells
(Cell morphology)
Original: Basaloid cells#have#central areas of eosinophilic ghost shadow cells and intermediate cells
#13103
middle Confidence
Subject:
Cells
(cell)
→
display
→
Object:
conspicuous_nucleoli
(Nuclear morphology)
Original: Cells#have#conspicuous nucleoli
#13102
middle Confidence
Subject:
Sarcomatous_tumor_cells
(Tumor cells)
→
display
→
Object:
relatively_scant_cytoplasm
(Cell morphology)
Original: Sarcomatous tumor cells#have#coarse chromatin and relatively scant cytoplasm
#13101
middle Confidence
Subject:
Sarcomatous_tumor_cells
(Tumor cells)
→
display
→
Object:
coarse_chromatin
(Nuclear morphology)
Original: Sarcomatous tumor cells#have#coarse chromatin and relatively scant cytoplasm
#13100
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
display
→
Object:
inconspicuous_nucleoli
(Nuclear morphology)
Original: Tumor cells#have#fine powdery chromatin and inconspicuous nucleoli
#13099
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
display
→
Object:
fine_powdery_chromatin
(Nuclear morphology)
Original: Tumor cells#have#fine powdery chromatin and inconspicuous nucleoli
#13052
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
identified_as
→
Object:
poorly_differentiated_small_cells
(Cell morphology)
Original: 10 cases#were identified as#poorly differentiated small cells
#13051
middle Confidence
Subject:
initial_symptom
(First symptoms)
→
is
→
Object:
dysphagia
(Clinical symptoms)
Original: Initial symptom#is#a rapidly growing painless or tender mass with restricted mouth opening and dysphagia
#13050
middle Confidence
Subject:
initial_symptom
(First symptoms)
→
is
→
Object:
restricted_mouth_opening
(Clinical symptoms)
Original: Initial symptom#is#a rapidly growing painless or tender mass with restricted mouth opening and dysphagia
#13049
middle Confidence
Subject:
initial_symptom
(First symptoms)
→
is
→
Object:
rapidly_growing_mass
(Clinical symptoms)
Original: Initial symptom#is#a rapidly growing painless or tender mass with restricted mouth opening and dysphagia
#13048
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
display
→
Object:
small_nucleoli
(Cell morphology)
Original: LBC preparation#showed#isolated tumor cells with small nucleoli
#13047
middle Confidence
Subject:
plasmacytoid_malignant_cells
(Tumor cells)
→
display
→
Object:
prominent_nucleoli
(Cell morphology)
Original: Cytopathologic examination#revealed#large undifferentiated plasmacytoid malignant cells with prominent nucleoli
#13018
middle Confidence
Subject:
Immunohistochemical stain
(Detection Methods)
→
includes
→
Object:
keratin 5/6
(Cytoskeletal proteins)
Original: Immunohistochemical stains#include#estrogen receptor/ progesterone receptor/ HER2/ AR/ endothelial growth factor receptor/ and keratin 5/6
#13017
middle Confidence
Subject:
Immunohistochemical stain
(Detection Methods)
→
includes
→
Object:
endothelial growth factor receptor
(Receptor protein)
Original: Immunohistochemical stains#include#estrogen receptor/ progesterone receptor/ HER2/ AR/ endothelial growth factor receptor/ and keratin 5/6
#13016
middle Confidence
Subject:
Immunohistochemical stain
(Detection Methods)
→
includes
→
Object:
androgen receptor
(Receptor protein)
Original: Immunohistochemical stains#include#estrogen receptor/ progesterone receptor/ HER2/ AR/ endothelial growth factor receptor/ and keratin 5/6
#13015
middle Confidence
Subject:
Woman
(patient)
→
is_diagnosed_with
→
Object:
Invasive lobular carcinoma
(Tumor)
Original: Women#are diagnosed with#invasive lobular carcinoma with histiocytoid features
#13014
middle Confidence
Subject:
Germ cell
(Germ cells)
→
shows_marker
→
Object:
Neoplastic germ cell marker
(Tumor markers)
Original: Germ cells#appear as#seminoma cells and stain positively for markers of neoplastic germ cells
#13012
middle Confidence
Subject:
primary_pulmonary_PNETs
(Tumor)
→
are_reported_with
→
Object:
immunohistochemical_features
(Immunohistochemical characteristics)
Original: six primary pulmonary primitive neuroectodermal tumors (PNETs)#are reported with#clinicopathological and immunohistochemical features
#13011
middle Confidence
Subject:
primary_pulmonary_PNETs
(Tumor)
→
are_reported_with
→
Object:
clinicopathological_features
(Clinical characteristics)
Original: six primary pulmonary primitive neuroectodermal tumors (PNETs)#are reported with#clinicopathological and immunohistochemical features
#13010
middle Confidence
Subject:
neoplasm
(Tumor)
→
resembles
→
Object:
small_cell_carcinoma_of_hypercalcemic_type
(Tumor subtype)
Original: neoplasm#is associated with#hypercalcemia and resembles small cell carcinoma of hypercalcemic type
#13009
middle Confidence
Subject:
neoplasm
(Tumor)
→
is_associated_with
→
Object:
hypercalcemia
(Metabolic abnormalities)
Original: neoplasm#is associated with#hypercalcemia and resembles small cell carcinoma of hypercalcemic type
#12986
middle Confidence
Subject:
FNA_of_neck_mass
(Cytology)
→
can_lead_to
→
Object:
misinterpretation_of_findings
(Misdiagnosis)
Original: FNA of neck mass#can lead to#misinterpretation of findings
#12985
middle Confidence
Subject:
diagnostic_imaging
(Imaging Technology)
→
shows
→
Object:
diffuse_pleural_thickening
(Imaging phenotype)
Original: diagnostic imaging#shows#variably calcified/ pleural-based masses and/or diffuse pleural thickening
#12984
middle Confidence
Subject:
diagnostic_imaging
(Imaging Technology)
→
shows
→
Object:
calculated_pleural_based_masses
(Imaging phenotype)
Original: diagnostic imaging#shows#variably calcified/ pleural-based masses and/or diffuse pleural thickening
#12983
middle Confidence
Subject:
familiarity_with_glomus_tumors
(Medical knowledge)
→
may_allow
→
Object:
accurate_preoperative_diagnosis
(Diagnosis conclusion)
Original: familiarity with glomus tumors and procurement of adequate material#may allow#accurate preoperative diagnosis
#12978
middle Confidence
Subject:
clear_cell_sarcoma
(Tumor type)
→
described_by
→
Object:
immunohistochemical_features
(Immunohistochemical characteristics)
Original: clear cell sarcoma cases#were described by#clinicopathologic/ ultrastructural/ and immunohistochemical features
#12977
middle Confidence
Subject:
clear_cell_sarcoma
(Tumor type)
→
described_by
→
Object:
ultrastructural_features
(Ultrastructural characteristics)
Original: clear cell sarcoma cases#were described by#clinicopathologic/ ultrastructural/ and immunohistochemical features
#12976
middle Confidence
Subject:
clear_cell_sarcoma
(Tumor type)
→
described_by
→
Object:
clinicopathologic_features
(Clinicopathological characteristics)
Original: clear cell sarcoma cases#were described by#clinicopathologic/ ultrastructural/ and immunohistochemical features
#12972
middle Confidence
Subject:
endometrial_cytology
(Cytology)
→
reveals
→
Object:
scattered_nonepithelial_cells
(Cytopathological characteristics)
Original: Endometrial cytology#revealed#adenocarcinoma cell clusters and scattered nonepithelial cells
#12971
middle Confidence
Subject:
endometrial_cytology
(Cytology)
→
reveals
→
Object:
adenocarcinoma_cell_clusters
(Cytopathological characteristics)
Original: Endometrial cytology#revealed#adenocarcinoma cell clusters and scattered nonepithelial cells
#12924
middle Confidence
Subject:
histopathology
(Technical methods)
→
revealed
→
Object:
solid_nests_of_tumor_cells_with_foamy_cytoplasm
(Organizational Structure)
Original: Histopathology#revealed#solid nests of tumor cells containing foamy cytoplasm and enlarged round nuclei with prominent nucleoli
#12923
middle Confidence
Subject:
ultrastructural_analysis
(Technical methods)
→
disclosed
→
Object:
features_similar_to_hepatocellular_carcinoma
(Tumor type)
Original: Ultrastructural analysis#disclosed#features similar to hepatocellular carcinoma
#12922
middle Confidence
Subject:
hepatoid_component_of_tumor
(Tumor composition)
→
characterized_by
→
Object:
discrete_masses_of_large_polyhedral_cells
(Cell structure)
Original: Hepatoid component of tumors#was characterized by#discrete masses/ nests/ and broad bands of large polyhedral cells with central nuclei and prominent nucleoli
#12921
middle Confidence
Subject:
adenocarcinoma_component
(Tumor composition)
→
had
→
Object:
tubule_growth_of_basophilic_cells
(Organizational Structure)
Original: Adenocarcinoma component#had#tubules or nested growth of basophilic cells
#12920
middle Confidence
Subject:
EBV-positive_inflammatory_FDC_sarcoma
(Tumor diseases)
→
is_characterized_by
→
Object:
gene_rearrangement
(Gene rearrangement)
Original: EBV-positive inflammatory FDC sarcoma#is characterized by#clinicopathological features/ histomorphology/ immunophenotype/ and gene rearrangement
#12919
middle Confidence
Subject:
EBV-positive_inflammatory_FDC_sarcoma
(Tumor diseases)
→
is_characterized_by
→
Object:
immunophenotype
(Immunophenotype)
Original: EBV-positive inflammatory FDC sarcoma#is characterized by#clinicopathological features/ histomorphology/ immunophenotype/ and gene rearrangement
#12918
middle Confidence
Subject:
EBV-positive_inflammatory_FDC_sarcoma
(Tumor diseases)
→
is_characterized_by
→
Object:
histomorphology
(Pathological morphological features)
Original: EBV-positive inflammatory FDC sarcoma#is characterized by#clinicopathological features/ histomorphology/ immunophenotype/ and gene rearrangement
#12917
middle Confidence
Subject:
EBV-positive_inflammatory_FDC_sarcoma
(Tumor diseases)
→
is_characterized_by
→
Object:
clinicopathological_features
(Clinicopathological characteristics)
Original: EBV-positive inflammatory FDC sarcoma#is characterized by#clinicopathological features/ histomorphology/ immunophenotype/ and gene rearrangement
#12870
middle Confidence
Subject:
duodenum
(organ)
→
is
→
Object:
most_common_site_for_extracolonic_adenomas_in_FAP_patients
(Disease distribution characteristics)
Original: duodenum#is#most common site for extracolonic adenomas in FAP patients
#12869
middle Confidence
Subject:
diagnosis_of_neuroblastoma
(Diagnostic Process)
→
should_be_possible_with
→
Object:
clinical_parameters
(Clinical parameters)
Original: diagnosis of neuroblastoma#should be possible with#morphologic methods and clinical parameters
#12868
middle Confidence
Subject:
diagnosis_of_neuroblastoma
(Diagnostic Process)
→
should_be_possible_with
→
Object:
morphologic_methods
(Diagnostic Methods)
Original: diagnosis of neuroblastoma#should be possible with#morphologic methods and clinical parameters
#12865
middle Confidence
Subject:
Biopsies
(Tissue samples)
→
are_obtained_for
→
Object:
Immunohistochemistry
(Immunohistochemical analysis)
Original: Biopsies#were obtained for#histomorphology and immunohistochemistry
#12864
middle Confidence
Subject:
Biopsies
(Tissue samples)
→
are_obtained_for
→
Object:
histomorphology
(Histomorphometric analysis)
Original: Biopsies#were obtained for#histomorphology and immunohistochemistry
#12839
middle Confidence
Subject:
silver_staining_analysis
(Molecular analysis technology)
→
may_help_distinguish
→
Object:
malignant_prostatic_tumors
(Malignant tumors)
Original: analysis of silver staining-positive material#may help distinguish between#benign and malignant prostatic tumors
#12838
middle Confidence
Subject:
silver_staining_analysis
(Molecular analysis technology)
→
may_help_distinguish
→
Object:
benign_prostatic_tumors
(Benign tumors)
Original: analysis of silver staining-positive material#may help distinguish between#benign and malignant prostatic tumors
#12797
middle Confidence
Subject:
scoring_system
(Rating system)
→
showed
→
Object:
positive_correlation_between_FNA_and_biopsy
(Diagnostic relevance)
Original: A scoring system#showed#a positive correlation between fine needle aspirates and paired excision biopsy specimens
#12795
middle Confidence
Subject:
Grade_III_carcinomas
(Tumor grade)
→
are
→
Object:
undifferentiated
(Disease phenotype)
Original: Grade III carcinomas#are#undifferentiated
#12794
middle Confidence
Subject:
Grade_IIb_carcinomas
(Tumor grade)
→
corresponds_to
→
Object:
poorly_differentiated_tumors
(Disease phenotype)
Original: Grade IIb carcinomas#correspond to#poorly differentiated tumors
#12793
middle Confidence
Subject:
Grade_Ia
(Tumor grade)
→
corresponds_to
→
Object:
highly_differentiated_glandular_carcinomas
(Disease phenotype)
Original: Grade Ia#corresponds to#highly differentiated glandular carcinomas
#12779
middle Confidence
Subject:
metanephric_adenoma
(Tumor type)
→
difficult_to_differentiate_from
→
Object:
Wilms_tumor
(Tumor type)
Original: Differentiating MA from WT#can be#difficult based on cytologic features
#12778
middle Confidence
Subject:
CD20
(Differentiation antigen)
→
is_used_for
→
Object:
immunocytochemical_staining_in_NHL
(Immunohistochemistry)
Original: CD3 and CD20 antibodies#are used for#immunocytochemical staining in NHL cases
#12777
middle Confidence
Subject:
CD3
(Differentiation antigen)
→
is_used_for
→
Object:
immunocytochemical_staining_in_NHL
(Immunohistochemistry)
Original: CD3 and CD20 antibodies#are used for#immunocytochemical staining in NHL cases
#12771
middle Confidence
Subject:
Brush_biopsy
(Pathology Detection Technology)
→
can_identify
→
Object:
syncytiotrophoblastic_cells
(Cell Type)
Original: Brush biopsy#can identify#cyto- and syncytiotrophoblastic cells
#12770
middle Confidence
Subject:
Brush_biopsy
(Pathology Detection Technology)
→
can_identify
→
Object:
cytotrophoblastic_cells
(Cell Type)
Original: Brush biopsy#can identify#cyto- and syncytiotrophoblastic cells
#12769
middle Confidence
Subject:
Esophageal_brushing
(Pathology Detection Technology)
→
revealed
→
Object:
prominent_nucleoli
(Nuclear characteristics)
Original: Esophageal brushing#revealed#malignant cells with large nuclei and prominent nucleoli
#12768
middle Confidence
Subject:
Esophageal_brushing
(Pathology Detection Technology)
→
revealed
→
Object:
malignant_cells_with_large_nuclei
(Cytopathological features)
Original: Esophageal brushing#revealed#malignant cells with large nuclei and prominent nucleoli
#12764
middle Confidence
Subject:
electron_microscopy
(Detection Technology)
→
revealed
→
Object:
glycogen_particles
(Ultrastructure)
Original: Electron microscopy#revealed#large convoluted nucleoli/ annulated lamellae/ and glycogen particles
#12763
middle Confidence
Subject:
electron_microscopy
(Detection Technology)
→
revealed
→
Object:
annulated_lamellae
(Ultrastructure)
Original: Electron microscopy#revealed#large convoluted nucleoli/ annulated lamellae/ and glycogen particles
#12762
middle Confidence
Subject:
electron_microscopy
(Detection Technology)
→
revealed
→
Object:
large_convoluted_nucleoli
(Ultrastructure)
Original: Electron microscopy#revealed#large convoluted nucleoli/ annulated lamellae/ and glycogen particles
#12761
middle Confidence
Subject:
tumor_cells
(cell)
→
exhibited
→
Object:
large_bizarre_nucleoli
(Nuclear abnormalities)
Original: Cells#exhibited#distinctive anisokaryosis and large/ sometimes bizarre/ nucleoli
#12760
middle Confidence
Subject:
tumor_cells
(cell)
→
exhibited
→
Object:
anisokaryosis
(Nuclear abnormalities)
Original: Cells#exhibited#distinctive anisokaryosis and large/ sometimes bizarre/ nucleoli
#12759
middle Confidence
Subject:
retraction_clefting
(Organizational structure)
→
was_observed_in
→
Object:
malignant_specimens
(Pathological samples)
Original: Retraction clefting#was observed in#38.6% of malignant specimens
#12758
middle Confidence
Subject:
glomerulations
(Organizational structure)
→
were_observed_in
→
Object:
malignant_specimens
(Pathological samples)
Original: Glomerulations#were observed in#15.3% of malignant specimens
#12757
middle Confidence
Subject:
collagenous_micronodules
(Organizational structure)
→
were_observed_in
→
Object:
malignant_specimens
(Pathological samples)
Original: Collagenous micronodules#were observed in#2% of malignant specimens
#12756
middle Confidence
Subject:
blue-tinged_mucinous_secretions
(Morphological characteristics of secretions)
→
were_observed_in
→
Object:
malignant_specimens
(Disease phenotype)
Original: Blue-tinged mucinous secretions#were observed in#52% of malignant specimens
#12755
middle Confidence
Subject:
multiple_nucleoli
(Nuclear morphology)
→
were_observed_in
→
Object:
malignant_specimens
(Disease phenotype)
Original: Multiple nucleoli#were observed in#64% of malignant specimens
#12754
middle Confidence
Subject:
marginated_nucleoli
(Nuclear morphology)
→
were_observed_in
→
Object:
benign_specimens
(Disease phenotype)
Original: Marginated nucleoli#were observed in#7% of benign specimens
#12753
middle Confidence
Subject:
marginated_nucleoli
(Nuclear morphology)
→
were_observed_in
→
Object:
malignant_specimens
(Disease phenotype)
Original: Marginated nucleoli#were observed in#88% of malignant specimens
#12752
middle Confidence
Subject:
prominent_nucleoli
(Nuclear morphology)
→
were_observed_in
→
Object:
benign_specimens
(Disease phenotype)
Original: Prominent nucleoli#were observed in#25% of benign specimens
#12751
middle Confidence
Subject:
prominent_nucleoli
(Nuclear morphology)
→
were_observed_in
→
Object:
malignant_specimens
(Disease phenotype)
Original: Prominent nucleoli#were observed in#94% of malignant specimens
#12736
middle Confidence
Subject:
FNAC_of_the_nodule
(Cytological examination method)
→
showed
→
Object:
loosely_cohesive_groups_of_cuboidal_tumor_cells_with_specific_cytologic_features
(Cell morphology)
Original: FNAC of the nodule#showed#loosely cohesive groups of cuboidal tumor cells with specific cytologic features
#12734
middle Confidence
Subject:
IL-1R
(Cytokine receptors)
→
is_proposed_as
→
Object:
tumor_marker
(Biomarkers)
Original: positivity for CD127/IL-1R#is proposed as#markers of this tumor
#12733
middle Confidence
Subject:
CD127
(Cytokine receptors)
→
is_proposed_as
→
Object:
tumor_marker
(Biomarkers)
Original: positivity for CD127/IL-1R#is proposed as#markers of this tumor
#12710
middle Confidence
Subject:
UBTF
(Transcription Factors)
→
is_sensitive_alternative_to
→
Object:
AgNOR_staining
(Dyeing technology)
Original: UBF staining#is#a sensitive alternative to AgNOR staining for detecting ribosomal activity in malignant tissues
#12708
middle Confidence
Subject:
UBTF
(Transcription Factors)
→
is_sensitive_alternative_to
→
Object:
AgNOR_staining
(Dyeing technology)
Original: UBF staining#is#a sensitive alternative to AgNOR staining for detecting ribosomal activity in malignant tissues
#12521
middle Confidence
Subject:
Animal-type_melanoma
(Tumor type)
→
is_categorized_as
→
Object:
melanocytic_tumor
(Tumor type)
Original: These tumors#have been categorized under#epithelioid blue nevus/ PEM/ and animal-type melanoma
#12520
middle Confidence
Subject:
Pigmented_epithelioid_melanocytoma
(Tumor type)
→
is_categorized_as
→
Object:
melanocytic_tumor
(Tumor type)
Original: These tumors#have been categorized under#epithelioid blue nevus/ PEM/ and animal-type melanoma
#12519
middle Confidence
Subject:
Epithelioid_blue_nevus
(Tumor type)
→
is_categorized_as
→
Object:
melanocytic_tumor
(Tumor type)
Original: These tumors#have been categorized under#epithelioid blue nevus/ PEM/ and animal-type melanoma
#12494
middle Confidence
Subject:
AgNOR_count
(Molecular markers)
→
is_proposed_as
→
Object:
method_for_evaluating_cell_replication
(Detection Methods)
Original: AgNOR count#is proposed as#a method for evaluating cell replication in human tumors
#12016
middle Confidence
Subject:
calpain_3_variant
(Protein variants)
→
is_downregulated_in
→
Object:
metastatic_melanoma_cells
(cancer cell)
Original: Calpain 3 variants#are downregulated in#vertical growth phase melanoma and metastatic melanoma cells
#12015
middle Confidence
Subject:
calpain_3_variant
(Protein variants)
→
is_downregulated_in
→
Object:
vertical_growth_phase_melanoma_cells
(cancer cell)
Original: Calpain 3 variants#are downregulated in#vertical growth phase melanoma and metastatic melanoma cells
#11992
middle Confidence
Subject:
BUD
(Cell proliferation markers)
→
labelling_index_evaluated_in
→
Object:
tumor_xenograft
(Tumor xenografts)
Original: Labelling indices of proliferation markers MIB1/ PCNA/ and BrdU#were evaluated in#tumor xenografts
#11991
middle Confidence
Subject:
PCNA
(Cell proliferation markers)
→
labelling_index_evaluated_in
→
Object:
tumor_xenograft
(Tumor xenografts)
Original: Labelling indices of proliferation markers MIB1/ PCNA/ and BrdU#were evaluated in#tumor xenografts
#11990
middle Confidence
Subject:
MIB1
(Cell proliferation markers)
→
labelling_index_evaluated_in
→
Object:
tumor_xenograft
(Tumor xenografts)
Original: Labelling indices of proliferation markers MIB1/ PCNA/ and BrdU#were evaluated in#tumor xenografts
#11943
middle Confidence
Subject:
Ag-NORs_counts
(Molecular markers)
→
are_measured_in
→
Object:
hepatocellular_carcinoma
(Hepatocellular carcinoma)
Original: Ag-NORs counts#are measured in#hepatocellular carcinoma (HCC)
#11908
middle Confidence
Subject:
intranuclear_dots
(endosome)
→
are_stained_with
→
Object:
silver_colloid_technique
(Silver colloid staining)
Original: Intranuclear dots representing nucleolar-associated proteins#are stained with#silver colloid technique in reactive and malignant pleural effusions
#11907
middle Confidence
Subject:
Silver_staining
(Silver staining)
→
did_not_detect
→
Object:
increase_in_active_NOR_number
(Increased number of active NORs)
Original: Silver staining#did not detect#an increase in the number of active NORs in cells of patients with malignant diseases
#11902
middle Confidence
Subject:
Silver_stained_AgNOR
(Silver staining AgNOR)
→
is_used_for
→
Object:
diagnostic_purpose
(Diagnostic Uses)
Original: Silver stained argyrophilic nucleolar organizer regions (AgNOR)#are used for#diagnostic and prognostic purposes
#11897
middle Confidence
Subject:
AgNOR_analysis
(Molecular analysis)
→
diagnoses
→
Object:
malignant_cells_in_serous_effusions
(Malignant cells)
Original: AgNOR analysis#diagnoses#malignant cells in serous effusions
#11891
middle Confidence
Subject:
NOR_activity
(Molecular analysis indicators)
→
is_studied_in
→
Object:
bone_marrow_cells_from_ANLL_patients
(Cell Type)
Original: NOR activity#is studied in#bone marrow cells from ALL and ANLL patients
#11890
middle Confidence
Subject:
NOR_activity
(Molecular analysis indicators)
→
is_studied_in
→
Object:
bone_marrow_cells_from_ALL_patients
(Cell Type)
Original: NOR activity#is studied in#bone marrow cells from ALL and ANLL patients
#11889
middle Confidence
Subject:
NOR_counts
(Molecular analysis indicators)
→
does_not_offer
→
Object:
histological_discrimination
(Pathological classification)
Original: NOR counts#do not offer#histological discrimination between endometrial and endocervical carcinomas
#11888
middle Confidence
Subject:
NOR_counts
(Molecular analysis indicators)
→
does_not_offer
→
Object:
histological_discrimination
(Pathological classification)
Original: NOR counts#do not offer#histological discrimination between endometrial and endocervical carcinomas
#11868
middle Confidence
Subject:
Nucleolar_organizer_regions
(Nucleolar organizer region)
→
are_evaluated_in
→
Object:
Thyroid_lesions
(disease)
Original: MIB-1 immunoreactivity and nucleolar organizer regions#are evaluated in#nonneoplastic and neoplastic thyroid lesions
#11867
middle Confidence
Subject:
MIB-1
(Proliferation-related proteins)
→
is_evaluated_in
→
Object:
Thyroid_lesions
(disease)
Original: MIB-1 immunoreactivity and nucleolar organizer regions#are evaluated in#nonneoplastic and neoplastic thyroid lesions
#11865
middle Confidence
Subject:
Cervical_cells
(Cell Type)
→
are_divided_into
→
Object:
Squamous_carcinoma
(disease)
Original: Cervical biopsies#were divided into#normal cervix/ HPVIO/ HPVIA/ and squamous carcinoma groups
#11864
middle Confidence
Subject:
Cervical_cells
(Cell Type)
→
are_divided_into
→
Object:
HPVIA
(organize)
Original: Cervical biopsies#were divided into#normal cervix/ HPVIO/ HPVIA/ and squamous carcinoma groups
#11863
middle Confidence
Subject:
Cervical_cells
(Cell Type)
→
are_divided_into
→
Object:
HPVIO
(organize)
Original: Cervical biopsies#were divided into#normal cervix/ HPVIO/ HPVIA/ and squamous carcinoma groups
#11862
middle Confidence
Subject:
Cervical_cells
(Cell Type)
→
are_divided_into
→
Object:
Normal_cervix
(organize)
Original: Cervical biopsies#were divided into#normal cervix/ HPVIO/ HPVIA/ and squamous carcinoma groups
#11861
middle Confidence
Subject:
Cohesive_cell_clusters
(Cell morphology)
→
help_in_diagnosing
→
Object:
BSC
(disease)
Original: Cohesive cell clusters#help in diagnosing#BSC on cytology specimens
#11830
middle Confidence
Subject:
AgNOR_proteins
(Nucleolar Organizing Region-associated Protein)
→
are_analyzed_in
→
Object:
basal_cell_carcinoma
(Basal cell carcinoma)
Original: AgNOR proteins#are analyzed in#squamous cell carcinoma (SCC)/ basal cell carcinoma (BCC)/ normal skin
#11829
middle Confidence
Subject:
AgNOR_proteins
(Nucleolar Organizing Region-associated Protein)
→
are_analyzed_in
→
Object:
squamous_cell_carcinoma
(Squamous cell carcinoma)
Original: AgNOR proteins#are analyzed in#squamous cell carcinoma (SCC)/ basal cell carcinoma (BCC)/ normal skin
#11811
middle Confidence
Subject:
AgNORs
(Nucleolar organizer region-associated protein)
→
assist_in
→
Object:
distinction_between_benign_and_malignant_breast_lesions
(Disease classification)
Original: Silver binding nucleolar organizer regions (AgNORs)#assist in#distinction between benign and malignant breast lesions
#11803
middle Confidence
Subject:
clinicopathological_parameters
(Clinical pathological parameters)
→
correlate_with
→
Object:
tumor_subtypes
(Tumor subtype)
Original: Clinicopathological parameters#correlate with#tumor subtypes in hepatic angiomyolipoma (HAML)
#11754
middle Confidence
Subject:
MKI67
(Cell proliferation marker proteins)
→
is_used_in
→
Object:
diagnosis_of_recurrent_meningiomas
(Tumor diagnostic markers)
Original: Ki67 labelling index/ AgNOR/ and DNA Feulgen staining#were used in#studying recurrent and atypical meningiomas
#11741
middle Confidence
Subject:
AgNOR_count
(Nucleolar organizer region-associated)
→
increases_with
→
Object:
carcinoma_grade
(Disease classification)
Original: AgNOR count#increased with#increasing grade of carcinoma
#11734
middle Confidence
Subject:
histopathological_diagnosis
(Histopathological diagnosis)
→
was_investigated_for
→
Object:
intraepithelial_squamous_lesions
(intraepithelial squamous lesion)
Original: 34 cases of intraepithelial squamous lesions#were investigated for#cytological and histopathological diagnosis
#11733
middle Confidence
Subject:
cytological_diagnosis
(Cytological diagnosis)
→
was_investigated_for
→
Object:
intraepithelial_squamous_lesions
(intraepithelial squamous lesion)
Original: 34 cases of intraepithelial squamous lesions#were investigated for#cytological and histopathological diagnosis
#11732
middle Confidence
Subject:
Adenoid_cystic_carcinoma
(Malignant tumors)
→
was_examined_in
→
Object:
histopathological_analysis
(Pathological analysis)
Original: Pleomorphic adenoma (PA) and adenoid cystic carcinoma (ACC)#were examined in#27 cases
#11731
middle Confidence
Subject:
Pleomorphic_adenoma
(Benign tumors)
→
was_examined_in
→
Object:
histopathological_analysis
(Pathological analysis)
Original: Pleomorphic adenoma (PA) and adenoid cystic carcinoma (ACC)#were examined in#27 cases
#11728
middle Confidence
Subject:
follicular_carcinoma
(Tumor type)
→
shows_difference_in
→
Object:
AgNOR_count
(Number of molecular modifications)
Original: Follicular adenomas and carcinomas#show#differences in nuclear volume and AgNOR counts
#11727
middle Confidence
Subject:
follicular_carcinoma
(Tumor type)
→
shows_difference_in
→
Object:
nuclear_volume
(Nuclear morphology)
Original: Follicular adenomas and carcinomas#show#differences in nuclear volume and AgNOR counts
#11726
middle Confidence
Subject:
follicular_adenoma
(Tumor type)
→
shows_difference_in
→
Object:
AgNOR_count
(Number of molecular modifications)
Original: Follicular adenomas and carcinomas#show#differences in nuclear volume and AgNOR counts
#11725
middle Confidence
Subject:
follicular_adenoma
(Tumor type)
→
shows_difference_in
→
Object:
nuclear_volume
(Nuclear morphology)
Original: Follicular adenomas and carcinomas#show#differences in nuclear volume and AgNOR counts
#11724
middle Confidence
Subject:
cell_proliferation_assessment
(Cellular process analysis)
→
is_useful_for
→
Object:
differential_diagnosis_of_IKA
(Diagnostic Process)
Original: Cell proliferation assessment#is useful for#differential diagnosis of WDSCC and IKA
#11723
middle Confidence
Subject:
cell_proliferation_assessment
(Cellular process analysis)
→
is_useful_for
→
Object:
differential_diagnosis_of_WDSCC
(Diagnostic Process)
Original: Cell proliferation assessment#is useful for#differential diagnosis of WDSCC and IKA
#11692
middle Confidence
Subject:
AgNOR
(Nucleolar organizing region-associated molecule)
→
is_expressed_in
→
Object:
neoplastic_lesions
(Lesion type)
Original: PCNA/ AgNOR/ oncogenes/ and tumor suppressor gene p53#are expressed in#preneoplastic and neoplastic lesions of rat and human livers
#11691
middle Confidence
Subject:
AgNOR
(Nucleolar organizing region-associated molecule)
→
is_expressed_in
→
Object:
preneoplastic_lesions
(Lesion type)
Original: PCNA/ AgNOR/ oncogenes/ and tumor suppressor gene p53#are expressed in#preneoplastic and neoplastic lesions of rat and human livers
#11689
middle Confidence
Subject:
NOR_staining_technique
(Dyeing technology)
→
is_applied_to
→
Object:
brain_tumor_biopsy_smears
(Tissue samples)
Original: NOR staining technique#is applied to#brain tumor biopsy smears
#11671
middle Confidence
Subject:
Ki-67_protein_immunoexpression
(Cell cycle proteins)
→
was_quantified_in
→
Object:
UA_tissue
(Disease Organization)
Original: AgNORs and Ki-67 protein immunoexpression#were quantified in#OKC/ DC/ and UA to evaluate metabolism and epithelial cell proliferation
#11670
middle Confidence
Subject:
Ki-67_protein_immunoexpression
(Cell cycle proteins)
→
was_quantified_in
→
Object:
DC_tissue
(Disease Organization)
Original: AgNORs and Ki-67 protein immunoexpression#were quantified in#OKC/ DC/ and UA to evaluate metabolism and epithelial cell proliferation
#11669
middle Confidence
Subject:
Ki-67_protein_immunoexpression
(Cell cycle proteins)
→
was_quantified_in
→
Object:
OKC_tissue
(Disease Organization)
Original: AgNORs and Ki-67 protein immunoexpression#were quantified in#OKC/ DC/ and UA to evaluate metabolism and epithelial cell proliferation
#11668
middle Confidence
Subject:
AgNORs
(Molecular markers)
→
were_quantified_in
→
Object:
UA_tissue
(Disease Organization)
Original: AgNORs and Ki-67 protein immunoexpression#were quantified in#OKC/ DC/ and UA to evaluate metabolism and epithelial cell proliferation
#11667
middle Confidence
Subject:
AgNORs
(Molecular markers)
→
were_quantified_in
→
Object:
DC_tissue
(Disease Organization)
Original: AgNORs and Ki-67 protein immunoexpression#were quantified in#OKC/ DC/ and UA to evaluate metabolism and epithelial cell proliferation
#11666
middle Confidence
Subject:
AgNORs
(Molecular markers)
→
were_quantified_in
→
Object:
OKC_tissue
(Disease Organization)
Original: AgNORs and Ki-67 protein immunoexpression#were quantified in#OKC/ DC/ and UA to evaluate metabolism and epithelial cell proliferation
#11664
middle Confidence
Subject:
ASC-H_case
(Clinical Cases)
→
showed
→
Object:
atrophy
(Tissue atrophy)
Original: ASC-H cases#showed#HSIL/ LSIL/ squamous metaplasia/ reactive changes/ benign glandular lesions/ and atrophy
#11663
middle Confidence
Subject:
ASC-H_case
(Clinical Cases)
→
showed
→
Object:
benign_glandular_lesion
(Benign glandular lesions)
Original: ASC-H cases#showed#HSIL/ LSIL/ squamous metaplasia/ reactive changes/ benign glandular lesions/ and atrophy
#11662
middle Confidence
Subject:
ASC-H_case
(Clinical Cases)
→
showed
→
Object:
reactive_changes
(Tissue reactive changes)
Original: ASC-H cases#showed#HSIL/ LSIL/ squamous metaplasia/ reactive changes/ benign glandular lesions/ and atrophy
#11661
middle Confidence
Subject:
ASC-H_case
(Clinical Cases)
→
showed
→
Object:
squamous_metaplasia
(Histopathological changes)
Original: ASC-H cases#showed#HSIL/ LSIL/ squamous metaplasia/ reactive changes/ benign glandular lesions/ and atrophy
#11660
middle Confidence
Subject:
ASC-H_case
(Clinical Cases)
→
showed
→
Object:
LSIL
(Disease phenotype)
Original: ASC-H cases#showed#HSIL/ LSIL/ squamous metaplasia/ reactive changes/ benign glandular lesions/ and atrophy
#11646
middle Confidence
Subject:
prostatic_intraepithelial_neoplasia
(Prostatic intraepithelial neoplasia)
→
correlates_with
→
Object:
cytological_feature_changes
(Changes in cytological features)
Original: Qualitative and quantitative features of prostatic intra-epithelial neoplasia#correlate with#changes in architectural and cytological features
#11645
middle Confidence
Subject:
prostatic_intraepithelial_neoplasia
(Prostatic intraepithelial neoplasia)
→
correlates_with
→
Object:
architectural_feature_changes
(Organizational structure changes)
Original: Qualitative and quantitative features of prostatic intra-epithelial neoplasia#correlate with#changes in architectural and cytological features
#11642
middle Confidence
Subject:
nucleolar_antigen
(Nuclear antigen)
→
is_reported_in
→
Object:
human_cancer
(Tumor)
Original: Nucleolar antigen#was reported in#a broad range of human cancers
#11641
middle Confidence
Subject:
nucleolar_immunofluorescence
(Immunofluorescence signal)
→
is_observed_in
→
Object:
hematological_neoplasm
(Tumor)
Original: Nucleolar immunofluorescence#was observed in#human adenocarcinomas/ squamous cell carcinomas/ sarcomas/ hematological neoplasms/ and other malignant tumors
#11640
middle Confidence
Subject:
nucleolar_immunofluorescence
(Immunofluorescence signal)
→
is_observed_in
→
Object:
sarcoma
(Tumor)
Original: Nucleolar immunofluorescence#was observed in#human adenocarcinomas/ squamous cell carcinomas/ sarcomas/ hematological neoplasms/ and other malignant tumors
#11639
middle Confidence
Subject:
nucleolar_immunofluorescence
(Immunofluorescence signal)
→
is_observed_in
→
Object:
squamous_cell_carcinoma
(Tumor)
Original: Nucleolar immunofluorescence#was observed in#human adenocarcinomas/ squamous cell carcinomas/ sarcomas/ hematological neoplasms/ and other malignant tumors
#11638
middle Confidence
Subject:
nucleolar_immunofluorescence
(Immunofluorescence signal)
→
is_observed_in
→
Object:
adenocarcinoma
(Tumor)
Original: Nucleolar immunofluorescence#was observed in#human adenocarcinomas/ squamous cell carcinomas/ sarcomas/ hematological neoplasms/ and other malignant tumors
#11623
middle Confidence
Subject:
immunostaining_with_trypsin
(Molecular detection technology)
→
helps_in
→
Object:
differentiating_ACCs
(Tumor Diagnosis)
Original: Immunostaining with trypsin/chymotrypsin#helps in#differentiating ACCs
#11622
middle Confidence
Subject:
fine-needle_aspiration_findings
(Diagnosis)
→
are_reported_for
→
Object:
basaloid_squamous_cell_carcinoma
(Tumor diseases)
Original: fine-needle aspiration findings#are reported for#16 cases of basaloid squamous cell carcinoma
#11616
middle Confidence
Subject:
Primary_cutaneous_diffuse_large_B-cell_lymphoma_leg_type
(Tumor)
→
mimics
→
Object:
subcutaneous_panniculitis-like_T-cell_lymphoma
(Tumor)
Original: Primary cutaneous diffuse large B-cell lymphoma/ leg type#mimics#subcutaneous panniculitis-like T-cell lymphoma
#11615
middle Confidence
Subject:
rectal_bleeding
(Clinical symptoms)
→
should_lead_to
→
Object:
malignant_melanoma_evaluation
(Diagnostic behavior)
Original: Patients with rectal bleeding#should undergo#malignant melanoma evaluation
#11580
middle Confidence
Subject:
nephrogenic_adenoma
(Adenoma)
→
is_reviewed_for
→
Object:
diagnostic_criteria
(Diagnostic criteria)
Original: nephrogenic adenoma#is reviewed for#diagnostic criteria and malignant mimics
#11569
middle Confidence
Subject:
Immunohistochemical_stains
(Diagnostic techniques)
→
were_applied_to_exclude
→
Object:
lymphoma
(Tumor)
Original: Immunohistochemical stains#were applied to exclude#common sinonasal undifferentiated neoplasms
#11568
middle Confidence
Subject:
Immunohistochemical_stains
(Diagnostic techniques)
→
were_applied_to_exclude
→
Object:
Ewing_sarcoma
(Tumor)
Original: Immunohistochemical stains#were applied to exclude#common sinonasal undifferentiated neoplasms
#11567
middle Confidence
Subject:
Immunohistochemical_stains
(Diagnostic techniques)
→
were_applied_to_exclude
→
Object:
rhabdomyosarcoma
(Tumor)
Original: Immunohistochemical stains#were applied to exclude#common sinonasal undifferentiated neoplasms
#11566
middle Confidence
Subject:
Immunohistochemical_stains
(Diagnostic techniques)
→
were_applied_to_exclude
→
Object:
melanoma
(Tumor)
Original: Immunohistochemical stains#were applied to exclude#common sinonasal undifferentiated neoplasms
#11565
middle Confidence
Subject:
Immunohistochemical_stains
(Diagnostic techniques)
→
were_applied_to_exclude
→
Object:
sinonasal_undifferentiated_carcinoma
(Tumor)
Original: Immunohistochemical stains#were applied to exclude#common sinonasal undifferentiated neoplasms
#11548
middle Confidence
Subject:
MYC
(Transcription Factors)
→
is_elevated_in
→
Object:
Diffuse_large_cell_lymphoma
(Tumor type)
Original: Diffuse large cell lymphomas#have#higher proliferative index evidenced by elevated PCNA/ c-myc p62/ and AgNOR scores
#11547
middle Confidence
Subject:
PCNA
(DNA polymerase accessory factors)
→
is_elevated_in
→
Object:
Diffuse_large_cell_lymphoma
(Tumor type)
Original: Diffuse large cell lymphomas#have#higher proliferative index evidenced by elevated PCNA/ c-myc p62/ and AgNOR scores
#11544
middle Confidence
Subject:
new_biomarkers
(Biomarkers)
→
supports
→
Object:
early_clinical_diagnosis
(Diagnostic Process)
Original: Screening new biomarkers#supports#early clinical diagnosis and targeted therapy of ccRCC
#11471
middle Confidence
Subject:
AgNOR_staining
(AgNOR staining)
→
distinguishes
→
Object:
malignant_lesions
(Malignant lesions)
Original: staining of AgNORs#distinguishes#benign and malignant lesions
#11470
middle Confidence
Subject:
AgNOR_staining
(AgNOR staining)
→
distinguishes
→
Object:
benign_lesions
(Benign lesions)
Original: staining of AgNORs#distinguishes#benign and malignant lesions
#11461
middle Confidence
Subject:
osteolytic_lesion
(Pathological characteristics)
→
causes
→
Object:
lingual_cortical_plate_perforation
(Anatomical lesions)
Original: osteolytic lesion#caused#buccal and lingual cortical plate perforation
#11460
middle Confidence
Subject:
osteolytic_lesion
(Pathological characteristics)
→
causes
→
Object:
buccal_cortical_plate_perforation
(Anatomical lesions)
Original: osteolytic lesion#caused#buccal and lingual cortical plate perforation
#11457
middle Confidence
Subject:
Histologic_examination
(Histological examination)
→
showed
→
Object:
diffuse_transmural_infiltration_of_malignant_cells
(Histological manifestations)
Original: Histologic examination#showed#diffuse transmural infiltration of malignant cells
#11451
middle Confidence
Subject:
Aspiration_cytology
(Cytological techniques)
→
was_performed_in
→
Object:
OGC_case
(Case)
Original: Aspiration cytology#was performed in#a case of OGC
#11424
middle Confidence
Subject:
HHV8_negative_effusion_based_lymphoma
(Disease Type)
→
overlaps_with
→
Object:
primary_effusion_lymphoma
(Disease Type)
Original: HHV8-negative effusion-based lymphoma#overlaps with#primary effusion lymphoma
#11419
middle Confidence
Subject:
Parameters
(Diagnostic parameters)
→
distinguish
→
Object:
small_cell_carcinoma_of_pulmonary_origin
(Disease Type)
Original: Parameters#distinguish#small cell malignancies from small cell carcinoma of pulmonary origin
#11418
middle Confidence
Subject:
Parameters
(Diagnostic parameters)
→
distinguish
→
Object:
small_cell_malignancies
(Disease Type)
Original: Parameters#distinguish#small cell malignancies from small cell carcinoma of pulmonary origin
#11416
middle Confidence
Subject:
biopsies_from_men_with_maldescended_testes
(Tissue samples)
→
contain
→
Object:
MGCT
(Tumor stage)
Original: Biopsies from men with maldescended testes#contain#intratubular germ cell neoplasia (IGCN) and MGCT in 1.8% of cases
#11415
middle Confidence
Subject:
biopsies_from_men_with_maldescended_testes
(Tissue samples)
→
contain
→
Object:
intratubular_germ_cell_neoplasia
(Tumor diseases)
Original: Biopsies from men with maldescended testes#contain#intratubular germ cell neoplasia (IGCN) and MGCT in 1.8% of cases
#11388
middle Confidence
Subject:
specific_features
(Cell structure characteristics)
→
correlate_with
→
Object:
pathological_aspects_of_adrenals
(Histopathological characteristics)
Original: specific features#correlate with#pathological aspects of adrenals
#11377
middle Confidence
Subject:
eosinophilic_granular_bodies
(Cell structure)
→
is_ancillary_sign_of
→
Object:
DNT
(Tumor type)
Original: The presence of eosinophilic granular bodies#was#an ancillary sign of DNT
#11353
middle Confidence
Subject:
MMCA
(Molecular diagnostic technology)
→
may_become
→
Object:
diagnostic_tool_for_neoplastic_changes_in_oral_smears
(Diagnostic Tools)
Original: MMCA#may become#a sensitive and highly specific diagnostic tool for neoplastic changes in oral smears
#11351
middle Confidence
Subject:
number_of_nucleoli_per_nucleus
(Number of nucleoli)
→
correlates_with
→
Object:
histopathological_groups
(Pathological classification)
Original: number of nucleoli per nucleus#correlates with#different histopathological groups
#11333
middle Confidence
Subject:
adenocarcinoma_in_situ
(Adenocarcinoma in situ)
→
studied_using
→
Object:
electron_microscopy
(Electron microscopy analysis)
Original: Adenocarcinoma in situ and microinvasive adenocarcinoma#studied using#cytology/ morphometry/ and electron microscopy
#11332
middle Confidence
Subject:
adenocarcinoma_in_situ
(Adenocarcinoma in situ)
→
studied_using
→
Object:
morphometry
(Morphometrics)
Original: Adenocarcinoma in situ and microinvasive adenocarcinoma#studied using#cytology/ morphometry/ and electron microscopy
#11331
middle Confidence
Subject:
adenocarcinoma_in_situ
(Adenocarcinoma in situ)
→
studied_using
→
Object:
Cytology
(Cytological analysis)
Original: Adenocarcinoma in situ and microinvasive adenocarcinoma#studied using#cytology/ morphometry/ and electron microscopy
#11309
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Fine needle aspiration biopsy)
→
was_performed_on
→
Object:
breast_carcinoma
(disease)
Original: Fine needle aspiration biopsy#was performed on#breast carcinoma during pregnancy and lactation
#11308
middle Confidence
Subject:
immunohistochemical_staining
(Molecular detection technology)
→
shows
→
Object:
negative_melanoma_marker_staining
(Molecular markers)
Original: immunohistochemical staining#showed#positive staining for cytokeratin and negative staining for melanoma markers
#11307
middle Confidence
Subject:
immunohistochemical_staining
(Molecular detection technology)
→
shows
→
Object:
positive_cytokeratin_staining
(Molecular markers)
Original: immunohistochemical staining#showed#positive staining for cytokeratin and negative staining for melanoma markers
#11306
middle Confidence
Subject:
tubular_or_ductal_pattern
(Histological structure)
→
is_observed_rarely_in
→
Object:
triple_negative_breast_cancer
(Tumor type)
Original: Tubular/ductal pattern#is observed rarely in#TNBCs
#11299
middle Confidence
Subject:
histological_specimen
(Histological specimens)
→
confirms
→
Object:
cytological_suspicion
(Diagnostic Process)
Original: Gross and histological specimens#confirmed#cytological suspicion
#11298
middle Confidence
Subject:
gross_specimen
(Histological specimens)
→
confirms
→
Object:
cytological_suspicion
(Diagnostic Process)
Original: Gross and histological specimens#confirmed#cytological suspicion
#11295
middle Confidence
Subject:
atypical_spermatogonia
(Germ cells)
→
are_relatively_frequent_in
→
Object:
vicinity_of_seminomas
(Organizational Distribution)
Original: Atypical spermatogonia#are relatively frequent in#the vicinity of testicular teratomas or seminomas
#11294
middle Confidence
Subject:
atypical_spermatogonia
(Germ cells)
→
are_relatively_frequent_in
→
Object:
vicinity_of_testicular_teratomas
(Organizational Distribution)
Original: Atypical spermatogonia#are relatively frequent in#the vicinity of testicular teratomas or seminomas
#11293
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_negative_for
→
Object:
S-100_protein
(Protein expression)
Original: Tumour cells#were negative for#smooth muscle actin/ desmin/ alpha-sarcomeric actin/ factor VIIIR: Ag/ and S-100 protein
#11292
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_negative_for
→
Object:
factor_VIIIR_Ag
(Protein expression)
Original: Tumour cells#were negative for#smooth muscle actin/ desmin/ alpha-sarcomeric actin/ factor VIIIR: Ag/ and S-100 protein
#11291
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_negative_for
→
Object:
alpha-sarcomeric_actin
(Protein expression)
Original: Tumour cells#were negative for#smooth muscle actin/ desmin/ alpha-sarcomeric actin/ factor VIIIR: Ag/ and S-100 protein
#11290
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_negative_for
→
Object:
desmin
(Protein expression)
Original: Tumour cells#were negative for#smooth muscle actin/ desmin/ alpha-sarcomeric actin/ factor VIIIR: Ag/ and S-100 protein
#11289
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_negative_for
→
Object:
smooth_muscle_actin
(Protein expression)
Original: Tumour cells#were negative for#smooth muscle actin/ desmin/ alpha-sarcomeric actin/ factor VIIIR: Ag/ and S-100 protein
#11288
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
showed
→
Object:
CD34_positivity
(Protein expression)
Original: Tumour cells#showed#positivity only for vimentin and CD34
#11287
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
showed
→
Object:
vimentin_positivity
(Protein expression)
Original: Tumour cells#showed#positivity only for vimentin and CD34
#11284
middle Confidence
Subject:
Medullary_breast_carcinoma
(Tumor tissue)
→
is_reported_with
→
Object:
histological_confirmation
(Histological evidence)
Original: Medullary breast carcinoma#is reported with#cytological features and histological confirmation
#11283
middle Confidence
Subject:
Medullary_breast_carcinoma
(Tumor tissue)
→
is_reported_with
→
Object:
cytological_features
(Cell morphology)
Original: Medullary breast carcinoma#is reported with#cytological features and histological confirmation
#11267
middle Confidence
Subject:
adenocarcinoma_endometrial_type
(Tumor tissue type)
→
was_initially_reported_as
→
Object:
endometrial_adenocarcinoma
(Disease diagnosis)
Original: Six out of the eight cases#were initially reported as#adenocarcinoma/ endometrial type
#11265
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
vimentin
(Cytoskeletal proteins)
Original: Tumor cells#were positive for#cytokeratins (CAM5.2 and AE1/AE3)/ CD31/ factor VIII-related antigen/ and vimentin
#11264
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
factor_VIII_related_antigen
(Vascular-associated protein)
Original: Tumor cells#were positive for#cytokeratins (CAM5.2 and AE1/AE3)/ CD31/ factor VIII-related antigen/ and vimentin
#11263
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
CD31
(Cell adhesion molecules)
Original: Tumor cells#were positive for#cytokeratins (CAM5.2 and AE1/AE3)/ CD31/ factor VIII-related antigen/ and vimentin
#11262
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
cytokeratins_AE1_AE3
(Cytoskeletal proteins)
Original: Tumor cells#were positive for#cytokeratins (CAM5.2 and AE1/AE3)/ CD31/ factor VIII-related antigen/ and vimentin
#11261
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_positive_for
→
Object:
cytokeratins_CAM5.2
(Cytoskeletal proteins)
Original: Tumor cells#were positive for#cytokeratins (CAM5.2 and AE1/AE3)/ CD31/ factor VIII-related antigen/ and vimentin
#11256
middle Confidence
Subject:
trucut_biopsy
(Tissue biopsy)
→
was_suspicious_of
→
Object:
soft_tissue_sarcoma
(Tumor type)
Original: Trucut biopsy#was suspicious of#soft tissue sarcoma
#11245
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
show
→
Object:
keratin_positivity
(Molecular markers)
Original: neoplastic cells#show#keratin positivity
#11233
middle Confidence
Subject:
cells_of_urothelial_neoplasms
(Tumor cells)
→
differ_morphologically_from
→
Object:
normal_elements
(Normal cells)
Original: cells of urothelial neoplasms#differ morphologically#from normal elements
#11229
middle Confidence
Subject:
simple_atrophy
(Histopathological phenotype)
→
shows
→
Object:
inconspicuous_nuclei
(Nuclear structure)
Original: simple atrophy#shows#inconspicuous nuclei
#11228
middle Confidence
Subject:
simple_atrophy
(Histopathological phenotype)
→
shows
→
Object:
minimal_cytoplasm
(Cytoplasmic structure)
Original: simple atrophy#shows#minimal cytoplasm
#11227
middle Confidence
Subject:
simple_atrophy
(Histopathological phenotype)
→
shows
→
Object:
intermediate_to_large_sized_glands
(Glandular structure)
Original: simple atrophy#shows#intermediate- to large-sized glands
#11226
middle Confidence
Subject:
lymphomatoid_papulosis
(Tumor type)
→
characterized_by
→
Object:
spontaneous_regression
(Clinical phenotype)
Original: lymphomatoid papulosis (LyP)#is characterized by#recurrent crops of papules/nodules up to 2 cm that undergo spontaneous regression
#11225
middle Confidence
Subject:
lymphomatoid_papulosis
(Tumor type)
→
characterized_by
→
Object:
recurrent_papules_or_nodes
(Clinical phenotype)
Original: lymphomatoid papulosis (LyP)#is characterized by#recurrent crops of papules/nodules up to 2 cm that undergo spontaneous regression
#11205
middle Confidence
Subject:
PAX8
(Transcription Factors)
→
is_diffusely_expressed_in
→
Object:
mucinous_follicular_carcinoma_cells
(Tumor cells)
Original: Mucinous follicular carcinoma#displayed#diffuse expression of thyroglobulin/ TTF-1/ CD56/ PAX-8
#11204
middle Confidence
Subject:
CD56
(Cell surface molecules)
→
is_diffusely_expressed_in
→
Object:
mucinous_follicular_carcinoma_cells
(Tumor cells)
Original: Mucinous follicular carcinoma#displayed#diffuse expression of thyroglobulin/ TTF-1/ CD56/ PAX-8
#11203
middle Confidence
Subject:
TTF-1
(Transcription Factors)
→
is_diffusely_expressed_in
→
Object:
mucinous_follicular_carcinoma_cells
(Tumor cells)
Original: Mucinous follicular carcinoma#displayed#diffuse expression of thyroglobulin/ TTF-1/ CD56/ PAX-8
#11202
middle Confidence
Subject:
Thyroglobulin
(Secretory proteins)
→
is_diffusely_expressed_in
→
Object:
mucinous_follicular_carcinoma_cells
(Tumor cells)
Original: Mucinous follicular carcinoma#displayed#diffuse expression of thyroglobulin/ TTF-1/ CD56/ PAX-8
#11201
middle Confidence
Subject:
CD23
(Cell surface molecules)
→
is_negative_in
→
Object:
DLBCL_tumor_cells
(Tumor cells)
Original: Five DLBCL cases#were positive for#CD5/ CD20/ surface immunoglobulin/ and negative for CD23
#11200
middle Confidence
Subject:
surface_immunoglobulin
(Immunoglobulins)
→
is_positive_in
→
Object:
DLBCL_tumor_cells
(Tumor cells)
Original: Five DLBCL cases#were positive for#CD5/ CD20/ surface immunoglobulin/ and negative for CD23
#11199
middle Confidence
Subject:
CD20
(Cell surface molecules)
→
is_positive_in
→
Object:
DLBCL_tumor_cells
(Tumor cells)
Original: Five DLBCL cases#were positive for#CD5/ CD20/ surface immunoglobulin/ and negative for CD23
#11198
middle Confidence
Subject:
CD5
(Cell surface molecules)
→
is_positive_in
→
Object:
DLBCL_tumor_cells
(Tumor cells)
Original: Five DLBCL cases#were positive for#CD5/ CD20/ surface immunoglobulin/ and negative for CD23
#11197
middle Confidence
Subject:
IGH/CCND1_rearrangement
(Chromosome rearrangement)
→
is_absent_in
→
Object:
tumor_sample
(Tumor samples)
Original: Three cases#were unclassifiable due to#lack of cyclin D1 expression and IGH/CCND1 rearrangement
#11196
middle Confidence
Subject:
cyclin_D1
(Cell cycle proteins)
→
lacks_expression
→
Object:
tumor_sample
(Tumor samples)
Original: Three cases#were unclassifiable due to#lack of cyclin D1 expression and IGH/CCND1 rearrangement
#11177
middle Confidence
Subject:
computed_tomogram
(Imaging Technology)
→
reveals
→
Object:
surrounding_soft_tissue_mass
(Tumor volume)
Original: Chest X-ray and computed tomogram#revealed#osteolysis and a surrounding soft tissue mass in the sixth right rib
#11176
middle Confidence
Subject:
computed_tomogram
(Imaging Technology)
→
reveals
→
Object:
osteolysis
(Bone destruction)
Original: Chest X-ray and computed tomogram#revealed#osteolysis and a surrounding soft tissue mass in the sixth right rib
#11175
middle Confidence
Subject:
chest_X-ray
(Imaging Technology)
→
reveals
→
Object:
osteolysis
(Bone destruction)
Original: Chest X-ray and computed tomogram#revealed#osteolysis and a surrounding soft tissue mass in the sixth right rib
#11172
middle Confidence
Subject:
Japanese_man
(Individual)
→
diagnosed_with
→
Object:
bone_metastasis
(disease)
Original: Japanese man#was diagnosed with#metastasis to the bones
#11145
middle Confidence
Subject:
histopathological_analysis
(Histological analysis)
→
shows
→
Object:
diffuse_myxoid_stroma_admixed_with_scant_collagen_fibrils
(Histological characteristics)
Original: Histopathological analysis#showed#a diffuse myxoid stroma admixed with scant collagen fibrils
#11133
middle Confidence
Subject:
silver_colloidal_staining_method
(Staining method)
→
distinguishes
→
Object:
malignant_thyroid_nodules
(Malignant nodules)
Original: silver colloidal staining method#distinguishes#non-neoplastic/ benign/ and malignant thyroid nodules
#11132
middle Confidence
Subject:
silver_colloidal_staining_method
(Staining method)
→
distinguishes
→
Object:
benign_thyroid_nodules
(Benign nodules)
Original: silver colloidal staining method#distinguishes#non-neoplastic/ benign/ and malignant thyroid nodules
#11131
middle Confidence
Subject:
silver_colloidal_staining_method
(Staining method)
→
distinguishes
→
Object:
non_neoplastic_thyroid_nodules
(Benign nodules)
Original: silver colloidal staining method#distinguishes#non-neoplastic/ benign/ and malignant thyroid nodules
#11130
middle Confidence
Subject:
Cytopathologists
(Medical professionals)
→
should_consider
→
Object:
malignant_melanoma
(disease)
Original: cytopathologists#should consider#malignant melanoma in spindle cell neoplasms of the mediastinum
#11046
middle Confidence
Subject:
Cytopathologist
(Medical professionals)
→
reviewed
→
Object:
Papanicolaou_stained_fine_needle_aspiration_specimen
(Tissue samples)
Original: Cytopathologists#reviewed#Papanicolaou-stained fine needle aspiration specimens
#10987
middle Confidence
Subject:
Multiple nucleoli
(Cell nucleolus morphology)
→
are_used_for
→
Object:
discrimination in cytological analysis
(Diagnostic Methods)
Original: Multiple nucleoli#are used for#discrimination in cytological analysis
#10986
middle Confidence
Subject:
Nuclear size variation
(Changes in nuclear size)
→
is_associated_with
→
Object:
cholangiocarcinoma
(Tumor)
Original: Nuclear size variation#is associated with#cholangiocarcinoma
#10985
middle Confidence
Subject:
Cytological atypia
(Abnormal cell morphology)
→
is_positive_for
→
Object:
carcinoembryonic antigen
(Tumor markers)
Original: Cytological atypia#is positive for#carcinoembryonic antigen
#10959
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_arranged_in
→
Object:
tubular_and_acinar_structures
(Cell structure characteristics)
Original: neoplastic cells#were arranged in#tubular and acinar structures
#10958
middle Confidence
Subject:
tumor
(Tumor tissue)
→
shows
→
Object:
well-demarcated_nodular_multilobular_mass
(Tumor morphological characteristics)
Original: tumor#showed#a well-demarcated/ nodular/ multilobular mass
#10956
middle Confidence
Subject:
bronchial_brushing_smears
(Cytology specimens)
→
revealed
→
Object:
large_clusters_of_neoplastic_cells
(Tumor cell clusters)
Original: bronchial brushing smears#revealed#large clusters of neoplastic cells with scant cytoplasm
#10954
middle Confidence
Subject:
tumor_cell_nuclei
(Nucleus)
→
showed
→
Object:
mitotic_figures_of_10_per_50_HPF
(Cell proliferation markers)
Original: Tumor cell nuclei#showed#absence of nucleoli and mitotic figures of 10 per 50 high power fields
#10933
middle Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
involves
→
Object:
carcinomas_with_oncocytic_differentiation
(Tumor type)
Original: differential diagnosis#involves#renal adenocarcinoma and carcinomas with oncocytic differentiation
#10932
middle Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
involves
→
Object:
renal_adenocarcinoma
(Tumor type)
Original: differential diagnosis#involves#renal adenocarcinoma and carcinomas with oncocytic differentiation
#10931
middle Confidence
Subject:
fine-needle_aspiration
(Diagnostic techniques)
→
was_performed_for
→
Object:
histologic_evaluation
(Histological evaluation)
Original: fine-needle aspiration#was performed for#cytologic and histologic evaluation
#10930
middle Confidence
Subject:
fine-needle_aspiration
(Diagnostic techniques)
→
was_performed_for
→
Object:
cytologic_evaluation
(Cytological evaluation)
Original: fine-needle aspiration#was performed for#cytologic and histologic evaluation
#10928
middle Confidence
Subject:
Low-grade_Apocrine_Intraductal_Carcinoma
(Tumor)
→
is_a
→
Object:
salivary_gland_tumor
(Tumor)
Original: Low-grade Apocrine Intraductal Carcinoma#is a#salivary gland tumor
#10866
middle Confidence
Subject:
patient
(patient)
→
has
→
Object:
Waldenstroms_macroglobulinemia
(Tumor type)
Original: patients#had#T-CLL/ T-PLL/ B-CLL/ B-PLL/ non-T-non-B-CLL/ Waldenstr?m's macroglobulinemia
#10865
middle Confidence
Subject:
patient
(patient)
→
has
→
Object:
non-T-non-B-CLL
(Tumor type)
Original: patients#had#T-CLL/ T-PLL/ B-CLL/ B-PLL/ non-T-non-B-CLL/ Waldenstr?m's macroglobulinemia
#10864
middle Confidence
Subject:
patient
(patient)
→
has
→
Object:
B-PLL
(Tumor type)
Original: patients#had#T-CLL/ T-PLL/ B-CLL/ B-PLL/ non-T-non-B-CLL/ Waldenstr?m's macroglobulinemia
#10863
middle Confidence
Subject:
patient
(patient)
→
has
→
Object:
B-CLL
(Tumor type)
Original: patients#had#T-CLL/ T-PLL/ B-CLL/ B-PLL/ non-T-non-B-CLL/ Waldenstr?m's macroglobulinemia
#10862
middle Confidence
Subject:
patient
(patient)
→
has
→
Object:
T-PLL
(Tumor type)
Original: patients#had#T-CLL/ T-PLL/ B-CLL/ B-PLL/ non-T-non-B-CLL/ Waldenstr?m's macroglobulinemia
#10861
middle Confidence
Subject:
patient
(patient)
→
has
→
Object:
T-CLL
(Tumor type)
Original: patients#had#T-CLL/ T-PLL/ B-CLL/ B-PLL/ non-T-non-B-CLL/ Waldenstr?m's macroglobulinemia
#10837
middle Confidence
Subject:
Sarcomatous_tumor_cells
(Tumor cells)
→
appear_as
→
Object:
single_cells
(Cell morphology)
Original: Sarcomatous tumor cells#form#small aggregates or appear alone
#10836
middle Confidence
Subject:
Sarcomatous_tumor_cells
(Tumor cells)
→
form
→
Object:
small_aggregates
(Cell morphology)
Original: Sarcomatous tumor cells#form#small aggregates or appear alone
#10825
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_described_as
→
Object:
small_to_medium_sized_round_to_spindle_shaped_cells_with_hyperchromatic_nuclei_and_inconspicuous_nucleoli
(Cell morphology)
Original: tumor cells#are described as#small to medium-sized round to spindle-shaped cells with hyperchromatic nuclei and inconspicuous nucleoli
#10824
middle Confidence
Subject:
prostatic_carcinomas
(Malignant tumors)
→
are_associated_with
→
Object:
prominent_large_eosinophilic_nucleoli_in_malignant_cells
(Cell nucleolus characteristics)
Original: prostatic carcinomas#are associated with#prominent large eosinophilic nucleoli in malignant cells
#10823
middle Confidence
Subject:
prominent_nucleoli_in_undifferentiated_neuroblasts
(Cell nucleolus characteristics)
→
correlate_with
→
Object:
clinical_groups
(Disease classification)
Original: prominent nucleoli in undifferentiated neuroblasts#correlate with#clinical groups
#10777
middle Confidence
Subject:
LINC01572
(lncRNA)
→
is_highly_expressed_in
→
Object:
tumor_tissue
(Tumor tissue)
Original: LINC01572#is highly expressed in#tumor tissue of NSCLC patients
#10669
middle Confidence
Subject:
CAPN3_variant
(Protein variants)
→
is_identified_in
→
Object:
human_melanoma_cells
(cancer cell)
Original: Muscle calpain 3 variants#are identified in#human melanoma cells
#10665
middle Confidence
Subject:
HMNA_positive_cells
(Cell population)
→
are_present_in
→
Object:
bone_marrow_of_acute_leukemia_patients
(Bone marrow tissue)
Original: HMNA-positive cells#are present in#bone marrow of acute leukemia patients
#10652
middle Confidence
Subject:
immunohistochemical_markers
(Molecular detection markers)
→
display
→
Object:
negative_or_weak_or_focal_staining
(Molecular test results)
Original: immunohistochemical markers#display#negative/ weak/ or focal staining in poorly differentiated PAC
#10617
middle Confidence
Subject:
histochemical_methods
(Histochemical methods)
→
are_used_for
→
Object:
thyroid_tumor_diagnosis
(Diagnostic Process)
Original: Stereological and histochemical methods#are used for#thyroid tumor diagnosis
#10616
middle Confidence
Subject:
stereological_methods
(Histological methods)
→
are_used_for
→
Object:
thyroid_tumor_diagnosis
(Diagnostic Process)
Original: Stereological and histochemical methods#are used for#thyroid tumor diagnosis
#10608
middle Confidence
Subject:
AgNOR_activity
(Molecular activity)
→
is_lower_in
→
Object:
benign_tumors
(Tumor type)
Original: AgNOR activity#is higher in#carcinomas compared to benign tumors/ chronic nasopharyngitis/ and normal nasopharyngeal tissues
#10594
middle Confidence
Subject:
tumors_with_unfavorable_prognosis
(Tumor tissue)
→
exhibit
→
Object:
thermographically_suspect_results
(Abnormal imaging findings)
Original: Tumors with unfavorable prognosis#preferentially exhibit#thermographically suspect results
#10566
middle Confidence
Subject:
immunostaining_with_anti-ALK1_antibody
(Immunohistochemistry)
→
shows
→
Object:
granular_cytoplasmic_staining_pattern
(Protein localization phenotype)
Original: immunostaining with anti-anaplastic lymphoma kinase (ALK) antibody/ ALK1#showed#finely granular cytoplasmic staining pattern
#10542
middle Confidence
Subject:
Fine_needle_aspiration
(Diagnostic techniques)
→
was_performed_during
→
Object:
most_recent_recurrence
(Disease process)
Original: Fine needle aspiration (FNA)#was performed during#the most recent recurrence
#10529
middle Confidence
Subject:
pancreatic_mass
(Tumor tissue)
→
resembles
→
Object:
neuroendocrine_tumors
(Tumor diseases)
Original: Pancreatic mass#is#large/ round/ demarcated/ and resembles neuroendocrine tumors
#10528
middle Confidence
Subject:
pleural_neoplasm
(Tumor tissue)
→
is_composed_of
→
Object:
small_cell_carcinoma
(Tumor diseases)
Original: pleural neoplasm#is composed of#malignant epithelial mesothelioma/ small- to medium-sized cells/ and small cell carcinoma
#10527
middle Confidence
Subject:
pleural_neoplasm
(Tumor tissue)
→
is_composed_of
→
Object:
small_to_medium_sized_cells
(Cell Type)
Original: pleural neoplasm#is composed of#malignant epithelial mesothelioma/ small- to medium-sized cells/ and small cell carcinoma
#10526
middle Confidence
Subject:
pleural_neoplasm
(Tumor tissue)
→
is_composed_of
→
Object:
malignant_epithelial_mesothelioma
(Tumor diseases)
Original: pleural neoplasm#is composed of#malignant epithelial mesothelioma/ small- to medium-sized cells/ and small cell carcinoma
#10525
middle Confidence
Subject:
fine-needle_aspiration_cytology
(Diagnostic techniques)
→
is_compared_for
→
Object:
small_cell_carcinoma
(Tumor diseases)
Original: fine-needle aspiration cytology#is compared for#basaloid squamous cell carcinoma and small cell carcinoma
#10524
middle Confidence
Subject:
fine-needle_aspiration_cytology
(Diagnostic techniques)
→
is_compared_for
→
Object:
basaloid_squamous_cell_carcinoma
(Tumor diseases)
Original: fine-needle aspiration cytology#is compared for#basaloid squamous cell carcinoma and small cell carcinoma
#10523
middle Confidence
Subject:
tumor
(Tumor tissue)
→
is_composed_of
→
Object:
clear_cells
(Cell Type)
Original: tumor#is composed of#clear cells in sheets or small nests
#10522
middle Confidence
Subject:
cystoscopic_biopsy
(Diagnostic Operations)
→
reveals
→
Object:
clear_cells
(Cell Type)
Original: cystoscopic biopsy#revealed#a mixed spindle cell and clear cell neoplasm with focal pigmentation
#10521
middle Confidence
Subject:
cystoscopic_biopsy
(Diagnostic Operations)
→
reveals
→
Object:
spindle_cells
(Cell Type)
Original: cystoscopic biopsy#revealed#a mixed spindle cell and clear cell neoplasm with focal pigmentation
#10514
middle Confidence
Subject:
histological_follow-up
(Diagnostic techniques)
→
showed
→
Object:
focal_high-grade_dysplasia
(Pathological characteristics)
Original: histological follow-ups#showed#intraductal papillary mucinous neoplasm with focal high-grade dysplasia
#10513
middle Confidence
Subject:
histological_follow-up
(Diagnostic techniques)
→
showed
→
Object:
intraductal_papillary_mucinous_neoplasm
(Tumor)
Original: histological follow-ups#showed#intraductal papillary mucinous neoplasm with focal high-grade dysplasia
#10508
middle Confidence
Subject:
patient
(patient)
→
presented_with
→
Object:
urinary_tract_infection
(Clinical symptoms)
Original: patient#presented with#persistent hematuria and urinary tract infections unresponsive to treatment
#10507
middle Confidence
Subject:
patient
(patient)
→
presented_with
→
Object:
persistent_hematuria
(Clinical symptoms)
Original: patient#presented with#persistent hematuria and urinary tract infections unresponsive to treatment
#10494
middle Confidence
Subject:
Fine-needle_aspiration
(Clinical operation)
→
is_performed_with
→
Object:
Serology
(Serologic testing)
Original: Fine-needle aspiration#is performed with#microbial culture/ biopsy/ radiographs/ exploratory laparotomy/ histopathology/ immunohistochemistry/ hematology/ and serology
#10493
middle Confidence
Subject:
Fine-needle_aspiration
(Clinical operation)
→
is_performed_with
→
Object:
Hematology
(Blood tests)
Original: Fine-needle aspiration#is performed with#microbial culture/ biopsy/ radiographs/ exploratory laparotomy/ histopathology/ immunohistochemistry/ hematology/ and serology
#10492
middle Confidence
Subject:
Fine-needle_aspiration
(Clinical operation)
→
is_performed_with
→
Object:
Immunohistochemistry
(Immunohistochemistry)
Original: Fine-needle aspiration#is performed with#microbial culture/ biopsy/ radiographs/ exploratory laparotomy/ histopathology/ immunohistochemistry/ hematology/ and serology
#10491
middle Confidence
Subject:
Fine-needle_aspiration
(Clinical operation)
→
is_performed_with
→
Object:
histopathology
(Histopathology)
Original: Fine-needle aspiration#is performed with#microbial culture/ biopsy/ radiographs/ exploratory laparotomy/ histopathology/ immunohistochemistry/ hematology/ and serology
#10490
middle Confidence
Subject:
Fine-needle_aspiration
(Clinical operation)
→
is_performed_with
→
Object:
exploratory_laparotomy
(Surgical procedures)
Original: Fine-needle aspiration#is performed with#microbial culture/ biopsy/ radiographs/ exploratory laparotomy/ histopathology/ immunohistochemistry/ hematology/ and serology
#10489
middle Confidence
Subject:
Fine-needle_aspiration
(Clinical operation)
→
is_performed_with
→
Object:
radiographs
(Imaging tests)
Original: Fine-needle aspiration#is performed with#microbial culture/ biopsy/ radiographs/ exploratory laparotomy/ histopathology/ immunohistochemistry/ hematology/ and serology
#10488
middle Confidence
Subject:
Fine-needle_aspiration
(Clinical operation)
→
is_performed_with
→
Object:
biopsy
(Histological examination)
Original: Fine-needle aspiration#is performed with#microbial culture/ biopsy/ radiographs/ exploratory laparotomy/ histopathology/ immunohistochemistry/ hematology/ and serology
#10487
middle Confidence
Subject:
Fine-needle_aspiration
(Clinical operation)
→
is_performed_with
→
Object:
microbial_culture
(Microbiological testing)
Original: Fine-needle aspiration#is performed with#microbial culture/ biopsy/ radiographs/ exploratory laparotomy/ histopathology/ immunohistochemistry/ hematology/ and serology
#10471
middle Confidence
Subject:
Tumor
(Tumor type)
→
is_characterized_by
→
Object:
cytoplasmic_inclusions
(Cell morphology)
Original: The tumor#is composed of#sheets of large polyhedra or round cells with eccentric round nuclei/ prominent nucleoli/ and cytoplasmic inclusions
#10470
middle Confidence
Subject:
Tumor
(Tumor type)
→
is_characterized_by
→
Object:
prominent_nucleoli
(Cell morphology)
Original: The tumor#is composed of#sheets of large polyhedra or round cells with eccentric round nuclei/ prominent nucleoli/ and cytoplasmic inclusions
#10469
middle Confidence
Subject:
Tumor
(Tumor type)
→
is_characterized_by
→
Object:
eccentric_round_nuclei
(Cell morphology)
Original: The tumor#is composed of#sheets of large polyhedra or round cells with eccentric round nuclei/ prominent nucleoli/ and cytoplasmic inclusions
#10468
middle Confidence
Subject:
Tumor
(Tumor type)
→
is_composed_of
→
Object:
sheets_of_large_round_cells
(Cell structure)
Original: The tumor#is composed of#sheets of large polyhedra or round cells with eccentric round nuclei/ prominent nucleoli/ and cytoplasmic inclusions
#10467
middle Confidence
Subject:
Tumor
(Tumor type)
→
is_composed_of
→
Object:
sheets_of_large_polyhedral_cells
(Cell structure)
Original: The tumor#is composed of#sheets of large polyhedra or round cells with eccentric round nuclei/ prominent nucleoli/ and cytoplasmic inclusions
#10466
middle Confidence
Subject:
Pancreatic_neoplasms_with_acinar_differentiation
(Tumor type)
→
include
→
Object:
pancreatoblastoma
(Tumor type)
Original: Pancreatic neoplasms with acinar differentiation#include#acinar cell carcinoma/ mixed carcinomas with acinar components/ cystic acinar lesions/ and pancreatoblastoma
#10465
middle Confidence
Subject:
Pancreatic_neoplasms_with_acinar_differentiation
(Tumor type)
→
include
→
Object:
cystic_acinar_lesions
(Tumor type)
Original: Pancreatic neoplasms with acinar differentiation#include#acinar cell carcinoma/ mixed carcinomas with acinar components/ cystic acinar lesions/ and pancreatoblastoma
#10464
middle Confidence
Subject:
Pancreatic_neoplasms_with_acinar_differentiation
(Tumor type)
→
include
→
Object:
mixed_carcinomas_with_acinar_components
(Tumor type)
Original: Pancreatic neoplasms with acinar differentiation#include#acinar cell carcinoma/ mixed carcinomas with acinar components/ cystic acinar lesions/ and pancreatoblastoma
#10463
middle Confidence
Subject:
Pancreatic_neoplasms_with_acinar_differentiation
(Tumor type)
→
include
→
Object:
acinar_cell_carcinoma
(Tumor type)
Original: Pancreatic neoplasms with acinar differentiation#include#acinar cell carcinoma/ mixed carcinomas with acinar components/ cystic acinar lesions/ and pancreatoblastoma
#10462
middle Confidence
Subject:
Pancreatic_acinar_lesions
(Tumor type)
→
encompass
→
Object:
benign_reactive_processes
(Benign lesions)
Original: Pancreatic acinar lesions#encompass#a broad spectrum of malignant tumors and benign reactive processes
#10461
middle Confidence
Subject:
Pancreatic_acinar_lesions
(Tumor type)
→
encompass
→
Object:
malignant_tumors
(Tumor type)
Original: Pancreatic acinar lesions#encompass#a broad spectrum of malignant tumors and benign reactive processes
#10460
middle Confidence
Subject:
Tumors
(Tumor type)
→
are_characterized_by
→
Object:
nuclei_surrounded_by_desmoplastic_stroma
(Cell morphology)
Original: Tumors#are composed of#cords and nests of eosinophilic cells with nuclei surrounded by desmoplastic stroma
#10459
middle Confidence
Subject:
Tumors
(Tumor type)
→
are_composed_of
→
Object:
nests_of_eosinophilic_cells
(Cell structure)
Original: Tumors#are composed of#cords and nests of eosinophilic cells with nuclei surrounded by desmoplastic stroma
#10458
middle Confidence
Subject:
Tumors
(Tumor type)
→
are_composed_of
→
Object:
cords_of_eosinophilic_cells
(Cell structure)
Original: Tumors#are composed of#cords and nests of eosinophilic cells with nuclei surrounded by desmoplastic stroma
#10457
middle Confidence
Subject:
Atypical_seminoma
(Tumor type)
→
is_characterized_by
→
Object:
vesicular_nuclei
(Cell morphology)
Original: Atypical seminoma#presents as#fragile large cells with scanty cytoplasm and vesicular nuclei
#10456
middle Confidence
Subject:
Atypical_seminoma
(Tumor type)
→
is_characterized_by
→
Object:
scanty_cytoplasm
(Cell morphology)
Original: Atypical seminoma#presents as#fragile large cells with scanty cytoplasm and vesicular nuclei
#10455
middle Confidence
Subject:
Malignant_fibrous_histiocytoma
(Tumor type)
→
is_characterized_by
→
Object:
histiocytic_cells
(Cell Type)
Original: Malignant fibrous histiocytoma#is defined as#a malignant primary bone tumor with fibrogenic and histiocytic cells
#10454
middle Confidence
Subject:
Malignant_fibrous_histiocytoma
(Tumor type)
→
is_characterized_by
→
Object:
fibrogenic_cells
(Cell Type)
Original: Malignant fibrous histiocytoma#is defined as#a malignant primary bone tumor with fibrogenic and histiocytic cells
#10443
middle Confidence
Subject:
tumor
(Tumor tissue)
→
is_distinguished_from
→
Object:
metastatic_adenocarcinoma
(Tumor tissue)
Original: distinguishing this tumor#from#papillary carcinoma of thyroid and metastatic adenocarcinoma
#10442
middle Confidence
Subject:
tumor
(Tumor tissue)
→
is_distinguished_from
→
Object:
papillary_carcinoma_of_thyroid
(Tumor tissue)
Original: distinguishing this tumor#from#papillary carcinoma of thyroid and metastatic adenocarcinoma
#10441
middle Confidence
Subject:
plump_epithelioid_cytomorphology
(Cell morphology)
→
is_helpful_in_distinguishing
→
Object:
cellular_DFs
(Tumor tissue)
Original: presence of plump to epithelioid cytomorphology#is helpful in distinguishing#fascicular CNT from cellular DFs
#10440
middle Confidence
Subject:
plump_epithelioid_cytomorphology
(Cell morphology)
→
is_helpful_in_distinguishing
→
Object:
fascicular_CNT
(Tumor tissue)
Original: presence of plump to epithelioid cytomorphology#is helpful in distinguishing#fascicular CNT from cellular DFs
#10413
middle Confidence
Subject:
clinical_evolution
(Clinical Progress)
→
was_more_typical_of
→
Object:
carcinoma
(Disease classification)
Original: Clinical evolution#was more typical of#carcinoma
#10408
middle Confidence
Subject:
IHC
(Immunohistochemistry)
→
was_performed_for
→
Object:
racemase_(PIN4)
(Protein complex)
Original: IHC#was performed for#p63/ high molecular weight cytokeratin/ and racemase (PIN4)
#10407
middle Confidence
Subject:
IHC
(Immunohistochemistry)
→
was_performed_for
→
Object:
high_molecular_weight_cytokeratin
(protein)
Original: IHC#was performed for#p63/ high molecular weight cytokeratin/ and racemase (PIN4)
#10406
middle Confidence
Subject:
IHC
(Immunohistochemistry)
→
was_performed_for
→
Object:
p63
(protein)
Original: IHC#was performed for#p63/ high molecular weight cytokeratin/ and racemase (PIN4)
#10394
middle Confidence
Subject:
a_65-year-old_man
(Patient characteristics)
→
presented_with
→
Object:
severe_anemia
(symptom)
Original: 65-year-old man#presented with#anorexia and severe anemia
#10393
middle Confidence
Subject:
a_65-year-old_man
(Patient characteristics)
→
presented_with
→
Object:
anorexia
(symptom)
Original: 65-year-old man#presented with#anorexia and severe anemia
#10391
middle Confidence
Subject:
Myxoma
(Tumor type)
→
is_seen_in
→
Object:
skin
(organ)
Original: Myxoma#is seen in#the heart and skin
#10390
middle Confidence
Subject:
Myxoma
(Tumor type)
→
is_seen_in
→
Object:
heart
(organ)
Original: Myxoma#is seen in#the heart and skin
#10385
middle Confidence
Subject:
MiB1_positivity
(Protein expression)
→
is_limited_to
→
Object:
small_and_medium_sized_inconspicuous_cells
(Cell Type)
Original: Positivity for MiB1#was limited to#small- and medium-sized/ inconspicuous cells
#10384
middle Confidence
Subject:
Atypical_cutaneous_fibrous_histiocytoma
(Tumor type)
→
is_characterized_by
→
Object:
striking_atypia_resembling_atypical_fibroxanthoma
(Morphological characteristics)
Original: Atypical cutaneous fibrous histiocytoma#is characterized by#striking atypia resembling atypical fibroxanthoma
#10383
middle Confidence
Subject:
primary_ALCL
(Tumor type)
→
can_mimic
→
Object:
other_pathologies
(Disease Type)
Original: primary ALCL#can mimic#glial neoplasms and other pathologies
#10382
middle Confidence
Subject:
primary_ALCL
(Tumor type)
→
can_mimic
→
Object:
glial_neoplasms
(Tumor type)
Original: primary ALCL#can mimic#glial neoplasms and other pathologies
#10378
middle Confidence
Subject:
histologic_examination
(Pathology testing)
→
showed
→
Object:
lack_of_squamous_differentiation
(Tumor pathological characteristics)
Original: Histologic examination#showed#extensive intraepithelial growth of cancer cells without glandular or squamous differentiation
#10377
middle Confidence
Subject:
histologic_examination
(Pathology testing)
→
showed
→
Object:
lack_of_glandular_differentiation
(Tumor pathological characteristics)
Original: Histologic examination#showed#extensive intraepithelial growth of cancer cells without glandular or squamous differentiation
#10376
middle Confidence
Subject:
histologic_examination
(Pathology testing)
→
showed
→
Object:
extensive_intraepithelial_growth_of_cancer_cells
(Tumor pathological characteristics)
Original: Histologic examination#showed#extensive intraepithelial growth of cancer cells without glandular or squamous differentiation
#10375
middle Confidence
Subject:
thyroid_nodule_FNA
(Cytology)
→
showed
→
Object:
inconspicuous_nucleoli
(Cell morphology)
Original: FNA of the thyroid nodule#showed#a cellular smear with spindle-shaped cells and inconspicuous nucleoli
#10374
middle Confidence
Subject:
thyroid_nodule_FNA
(Cytology)
→
showed
→
Object:
cellular_smear_with_spindle-shaped_cells
(Cell morphology)
Original: FNA of the thyroid nodule#showed#a cellular smear with spindle-shaped cells and inconspicuous nucleoli
#10373
middle Confidence
Subject:
diagnosis
(Diagnostic behavior)
→
depends_on
→
Object:
histopathological_evaluation
(Pathological evaluation)
Original: Correct diagnosis#depends on#pathologist awareness and histopathological evaluation
#10372
middle Confidence
Subject:
glial_fibrillary_acidic_protein
(protein)
→
immunostaining_result
→
Object:
negative
(Negative signs)
Original: Following antibodies#gave#negative results: desmin/ actins/ S-100 protein/ pancytokeratin/ epithelial membrane antigen/ chromogranin A/ neurofilament protein/ myelinic basic protein/ glial fibrillary acidic protein
#10371
middle Confidence
Subject:
myelin_basic_protein
(protein)
→
immunostaining_result
→
Object:
negative
(Negative signs)
Original: Following antibodies#gave#negative results: desmin/ actins/ S-100 protein/ pancytokeratin/ epithelial membrane antigen/ chromogranin A/ neurofilament protein/ myelinic basic protein/ glial fibrillary acidic protein
#10370
middle Confidence
Subject:
neurofilament_protein
(protein)
→
immunostaining_result
→
Object:
negative
(Negative signs)
Original: Following antibodies#gave#negative results: desmin/ actins/ S-100 protein/ pancytokeratin/ epithelial membrane antigen/ chromogranin A/ neurofilament protein/ myelinic basic protein/ glial fibrillary acidic protein
#10369
middle Confidence
Subject:
chromogranin_A
(protein)
→
immunostaining_result
→
Object:
negative
(Negative signs)
Original: Following antibodies#gave#negative results: desmin/ actins/ S-100 protein/ pancytokeratin/ epithelial membrane antigen/ chromogranin A/ neurofilament protein/ myelinic basic protein/ glial fibrillary acidic protein
#10368
middle Confidence
Subject:
epithelial_membrane_antigen
(protein)
→
immunostaining_result
→
Object:
negative
(Negative signs)
Original: Following antibodies#gave#negative results: desmin/ actins/ S-100 protein/ pancytokeratin/ epithelial membrane antigen/ chromogranin A/ neurofilament protein/ myelinic basic protein/ glial fibrillary acidic protein
#10367
middle Confidence
Subject:
pancytokeratin
(protein)
→
immunostaining_result
→
Object:
negative
(Negative signs)
Original: Following antibodies#gave#negative results: desmin/ actins/ S-100 protein/ pancytokeratin/ epithelial membrane antigen/ chromogranin A/ neurofilament protein/ myelinic basic protein/ glial fibrillary acidic protein
#10366
middle Confidence
Subject:
S-100_protein
(protein)
→
immunostaining_result
→
Object:
negative
(Negative signs)
Original: Following antibodies#gave#negative results: desmin/ actins/ S-100 protein/ pancytokeratin/ epithelial membrane antigen/ chromogranin A/ neurofilament protein/ myelinic basic protein/ glial fibrillary acidic protein
#10365
middle Confidence
Subject:
actins
(protein)
→
immunostaining_result
→
Object:
negative
(Negative signs)
Original: Following antibodies#gave#negative results: desmin/ actins/ S-100 protein/ pancytokeratin/ epithelial membrane antigen/ chromogranin A/ neurofilament protein/ myelinic basic protein/ glial fibrillary acidic protein
#10364
middle Confidence
Subject:
desmin
(protein)
→
immunostaining_result
→
Object:
negative
(Negative signs)
Original: Following antibodies#gave#negative results: desmin/ actins/ S-100 protein/ pancytokeratin/ epithelial membrane antigen/ chromogranin A/ neurofilament protein/ myelinic basic protein/ glial fibrillary acidic protein
#10363
middle Confidence
Subject:
immunohistochemical_staining_pattern
(Immunohistochemical pattern)
→
is_similar_to
→
Object:
conventional_cellular_neurothekeomas
(Benign tumors)
Original: immunohistochemical staining pattern#is similar to#conventional cellular neurothekeomas
#10339
middle Confidence
Subject:
in_situ_hybridization_for_EBER1
(Molecular detection technology)
→
demonstrated
→
Object:
EBV_in_tumor_cells
(Viral infection)
Original: In situ hybridization for EBER1 message#demonstrated#EBV in tumor cells
#10338
middle Confidence
Subject:
S100B
(Calcium Binding Protein)
→
is_negative_in
→
Object:
tumor_cells
(Tumor cells)
Original: Tumor cells#were negative for#keratin 7 and S100 protein
#10337
middle Confidence
Subject:
KRT7
(Keratin)
→
is_negative_in
→
Object:
tumor_cells
(Tumor cells)
Original: Tumor cells#were negative for#keratin 7 and S100 protein
#10336
middle Confidence
Subject:
neuroendocrine_markers
(Neuroendocrine markers)
→
is_positive_in
→
Object:
tumor_cells
(Tumor cells)
Original: Tumor cells#displayed#positivity for keratin 20 and neuroendocrine markers
#10335
middle Confidence
Subject:
KRT20
(Keratin)
→
is_positive_in
→
Object:
tumor_cells
(Tumor cells)
Original: Tumor cells#displayed#positivity for keratin 20 and neuroendocrine markers
#10290
middle Confidence
Subject:
diagnostic_pathological_features
(Diagnostic pathological features)
→
are_investigated_in
→
Object:
endometrial_carcinomas_in_women_under_40
(Endometrial cancer (women < 40 years old))
Original: study#investigates#diagnostic pathological features of endometrial carcinomas in women under 40 years of age
#10122
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
exhibit
→
Object:
reduced_cytoplasmic_organelles
(Reduced organelles)
Original: neoplastic cells#exhibit#reduced cytoplasmic organelles
#10110
middle Confidence
Subject:
Micronucleus_test
(Molecular detection methods)
→
detects
→
Object:
metanuclear_aberrations
(Cell abnormalities)
Original: Micronucleus test#finds#micronucleated cells and metanuclear aberrations
#10109
middle Confidence
Subject:
Micronucleus_test
(Molecular detection methods)
→
detects
→
Object:
micronucleated_cells
(Cell abnormalities)
Original: Micronucleus test#finds#micronucleated cells and metanuclear aberrations
#9899
middle Confidence
Subject:
AgNORs
(Molecular markers)
→
was_assessed_in
→
Object:
keratosis
(Keratosis)
Original: Expression of PCNA/ ck16/ and AgNORs#was assessed in#normal oral mucosa/ lichen planus/ and keratosis
#9898
middle Confidence
Subject:
AgNORs
(Molecular markers)
→
was_assessed_in
→
Object:
lichen_planus
(Inflammatory diseases)
Original: Expression of PCNA/ ck16/ and AgNORs#was assessed in#normal oral mucosa/ lichen planus/ and keratosis
#9897
middle Confidence
Subject:
AgNORs
(Molecular markers)
→
was_assessed_in
→
Object:
normal_oral_mucosa
(Normal tissue)
Original: Expression of PCNA/ ck16/ and AgNORs#was assessed in#normal oral mucosa/ lichen planus/ and keratosis
#9896
middle Confidence
Subject:
PCNA
(Proliferation-related proteins)
→
was_assessed_in
→
Object:
keratosis
(Keratosis)
Original: Expression of PCNA/ ck16/ and AgNORs#was assessed in#normal oral mucosa/ lichen planus/ and keratosis
#9895
middle Confidence
Subject:
PCNA
(Proliferation-related proteins)
→
was_assessed_in
→
Object:
lichen_planus
(Inflammatory diseases)
Original: Expression of PCNA/ ck16/ and AgNORs#was assessed in#normal oral mucosa/ lichen planus/ and keratosis
#9894
middle Confidence
Subject:
PCNA
(Proliferation-related proteins)
→
was_assessed_in
→
Object:
normal_oral_mucosa
(Normal tissue)
Original: Expression of PCNA/ ck16/ and AgNORs#was assessed in#normal oral mucosa/ lichen planus/ and keratosis
#9893
middle Confidence
Subject:
AgNOR_staining
(Dyeing technology)
→
was_employed_in
→
Object:
endometrium_specimens
(Tissue specimens)
Original: AgNOR staining#was employed in#endometrium specimens
#9799
middle Confidence
Subject:
nucleolar_organizer_regions
(Nucleolar organizer region)
→
are_analyzed_in
→
Object:
small_cell_melanoma
(Disease phenotype)
Original: Nucleolar organizer regions (NORs)#are analyzed in#small cell (nevoid) melanoma
#9798
middle Confidence
Subject:
Argyrophil_stain_for_NORs
(Silver staining analysis)
→
is_applied_to
→
Object:
benign_breast_tumors
(Benign breast tumors)
Original: Argyrophil stain for NORs#is applied to#malignant and benign breast tumors
#9797
middle Confidence
Subject:
Argyrophil_stain_for_NORs
(Silver staining analysis)
→
is_applied_to
→
Object:
malignant_breast_tumors
(Malignant breast tumor)
Original: Argyrophil stain for NORs#is applied to#malignant and benign breast tumors
#9795
middle Confidence
Subject:
nucleolar_organizer_regions
(Nucleolar organizer region)
→
are_evaluated_in
→
Object:
cervical_intraepithelial_neoplasia
(Disease phenotype)
Original: Nucleolar organizer regions (NORs)#are evaluated in#cervical intraepithelial neoplasia
#9638
middle Confidence
Subject:
Endoscopic_retrograde_cholangiography
(Imaging tests)
→
disclosed
→
Object:
irregular_narrowing_of_common_biliary_duct
(Abnormal tissue morphology)
Original: Endoscopic retrograde cholangiography#disclosed#an irregular narrowing of the common biliary duct
#9627
middle Confidence
Subject:
60-year-old_female
(Patient characteristics)
→
was_diagnosed_with
→
Object:
Malignant_melanotic_nerve_sheath_tumor_(MMNST)
(Tumor)
Original: 60-year-old female#was diagnosed with#Malignant melanotic nerve sheath tumor (MMNST)
#9625
middle Confidence
Subject:
Computed_tomography-guided_biopsy
(Imaging Technology)
→
was_performed_on
→
Object:
intramuscular_paraspinal_mass
(Anatomy)
Original: Computed tomography-guided biopsy#was performed on#retroperitoneal abdominal and intramuscular paraspinal masses
#9624
middle Confidence
Subject:
Computed_tomography-guided_biopsy
(Imaging Technology)
→
was_performed_on
→
Object:
retroperitoneal_abdominal_mass
(Anatomy)
Original: Computed tomography-guided biopsy#was performed on#retroperitoneal abdominal and intramuscular paraspinal masses
#9504
middle Confidence
Subject:
pathological_diagnosis
(Diagnostic techniques)
→
is_discussed_in
→
Object:
tumor
(Disease phenotype)
Original: Clinicopathological features and pathological diagnosis#are discussed in#this tumor
#9503
middle Confidence
Subject:
clinicopathological_feature
(Clinical characteristics)
→
is_discussed_in
→
Object:
tumor
(Disease phenotype)
Original: Clinicopathological features and pathological diagnosis#are discussed in#this tumor
#9498
middle Confidence
Subject:
smear_from_fine_needle_aspiration_biopsy
(Histological samples)
→
shows
→
Object:
small_round_cell
(Cell Type)
Original: Smears prepared from fine needle aspiration biopsy#were#moderately cellular with small/ round cells arranged singly and in loosely cohesive clusters
#9497
middle Confidence
Subject:
smear_from_fine_needle_aspiration_biopsy
(Histological samples)
→
shows
→
Object:
moderate_cellularity
(Organizational characteristics)
Original: Smears prepared from fine needle aspiration biopsy#were#moderately cellular with small/ round cells arranged singly and in loosely cohesive clusters
#9479
middle Confidence
Subject:
Immunohistochemical_study
(Diagnostic techniques)
→
was_negative_for
→
Object:
S-100_protein
(Cytoskeletal proteins)
Original: Pan-keratins/ actin/ desmin/ CD34/ CD10/ and S-100 protein#were negative in#the immunohistochemical study
#9478
middle Confidence
Subject:
Immunohistochemical_study
(Diagnostic techniques)
→
was_negative_for
→
Object:
CD10
(Cell surface antigens)
Original: Pan-keratins/ actin/ desmin/ CD34/ CD10/ and S-100 protein#were negative in#the immunohistochemical study
#9477
middle Confidence
Subject:
Immunohistochemical_study
(Diagnostic techniques)
→
was_negative_for
→
Object:
CD34
(Cell surface antigens)
Original: Pan-keratins/ actin/ desmin/ CD34/ CD10/ and S-100 protein#were negative in#the immunohistochemical study
#9476
middle Confidence
Subject:
Immunohistochemical_study
(Diagnostic techniques)
→
was_negative_for
→
Object:
desmin
(Cytoskeletal proteins)
Original: Pan-keratins/ actin/ desmin/ CD34/ CD10/ and S-100 protein#were negative in#the immunohistochemical study
#9475
middle Confidence
Subject:
Immunohistochemical_study
(Diagnostic techniques)
→
was_negative_for
→
Object:
actin
(Cytoskeletal proteins)
Original: Pan-keratins/ actin/ desmin/ CD34/ CD10/ and S-100 protein#were negative in#the immunohistochemical study
#9474
middle Confidence
Subject:
Immunohistochemical_study
(Diagnostic techniques)
→
was_negative_for
→
Object:
Pan-keratins
(Cytoskeletal proteins)
Original: Pan-keratins/ actin/ desmin/ CD34/ CD10/ and S-100 protein#were negative in#the immunohistochemical study
#9473
middle Confidence
Subject:
Immunohistochemical_study
(Diagnostic techniques)
→
showed_positivity_for
→
Object:
factor_XIIIa
(Coagulation factors)
Original: Immunohistochemical study#showed positivity for#vimentin and factor XIIIa
#9472
middle Confidence
Subject:
Immunohistochemical_study
(Diagnostic techniques)
→
showed_positivity_for
→
Object:
vimentin
(Cytoskeletal proteins)
Original: Immunohistochemical study#showed positivity for#vimentin and factor XIIIa
#9446
middle Confidence
Subject:
Thoracoscopy
(Detection Methods)
→
revealed
→
Object:
diffuse_nodular_thickening_of_left_parietal_pleura
(Histological manifestations)
Original: Thoracoscopy#revealed#diffuse nodular thickening of the left parietal pleura
#9445
middle Confidence
Subject:
Computed_tomogram
(Imaging tests)
→
showed
→
Object:
7.5-cm_pleural_mass
(Imaging findings)
Original: Computed tomogram#showed#a left pleural effusion and a 7.5-cm pleural mass
#9444
middle Confidence
Subject:
Computed_tomogram
(Imaging tests)
→
showed
→
Object:
left_pleural_effusion
(Imaging findings)
Original: Computed tomogram#showed#a left pleural effusion and a 7.5-cm pleural mass
#9421
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
contain
→
Object:
eosinophilic_cytoplasm
(Cytoplasmic structure)
Original: tumor cells#contain#well-defined nucleoli and eosinophilic cytoplasm
#9420
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
contain
→
Object:
well-defined_nucleoli
(Nuclear structure)
Original: tumor cells#contain#well-defined nucleoli and eosinophilic cytoplasm
#9417
middle Confidence
Subject:
large_polygonal_cells
(Tumor cells)
→
contain
→
Object:
prominent_nucleoli
(Nuclear structure)
Original: large polygonal cells#contain#prominent nucleoli
#9416
middle Confidence
Subject:
cutaneous_ENKLN_cells
(Tumor cells)
→
contain
→
Object:
inconspicuous_nucleoli
(Nuclear structure)
Original: cells in cutaneous ENKLN#contain#inconspicuous nucleoli
#9415
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibit
→
Object:
prominent_nucleoli
(Nuclear structure)
Original: tumor cells#exhibit#vesicular nuclei and prominent nucleoli
#9414
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
exhibit
→
Object:
vesicular_nuclei
(Nuclear structure)
Original: tumor cells#exhibit#vesicular nuclei and prominent nucleoli
#9413
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
contain
→
Object:
non-prominent_nucleoli
(Nuclear structure)
Original: tumor cells#contain#stippled chromatin and non-prominent nucleoli
#9412
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
contain
→
Object:
stippled_chromatin
(Nuclear structure)
Original: tumor cells#contain#stippled chromatin and non-prominent nucleoli
#9392
middle Confidence
Subject:
histopathological_examination
(Histopathological examination)
→
showed
→
Object:
sheets_of_epithelioid_cells
(Cell morphology)
Original: Histopathological examination#showed#islands and sheets of spindle and epithelioid cells with little intervening stroma
#9391
middle Confidence
Subject:
histopathological_examination
(Histopathological examination)
→
showed
→
Object:
islands_of_spindle_cells
(Cell morphology)
Original: Histopathological examination#showed#islands and sheets of spindle and epithelioid cells with little intervening stroma
#9385
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_composed_of
→
Object:
monotonous_signet-ring_cells_with_fine_chromatin
(Cell morphology)
Original: tumor cells#were composed of#monotonous-appearing signet-ring cells with fine chromatin/ variably conspicuous nucleoli/ brisk mitotic figures/ and spotty necrosis
#9384
middle Confidence
Subject:
cytomorphologic_features
(Cell morphology)
→
included
→
Object:
large_tumor_cells_with_high_nuclear_to_cytoplasmic_ratios
(Cell morphology)
Original: cytomorphologic features#included#large tumor cells with high nuclear to cytoplasmic ratios/ vesicular chromatin/ and prominent nucleoli
#9383
middle Confidence
Subject:
differential_diagnosis_of_PHE_of_bone
(Diagnostic Process)
→
includes
→
Object:
epithelioid_sarcoma
(Epithelioid sarcoma)
Original: differential diagnosis of PHE of bone#includes#osteoblastoma/ epithelioid angiosarcoma/ metastatic carcinoma/ metastatic rhabdomyosarcoma/ and epithelioid sarcoma
#9382
middle Confidence
Subject:
differential_diagnosis_of_PHE_of_bone
(Diagnostic Process)
→
includes
→
Object:
metastatic_rhabdomyosarcoma
(Rhabdomyosarcoma)
Original: differential diagnosis of PHE of bone#includes#osteoblastoma/ epithelioid angiosarcoma/ metastatic carcinoma/ metastatic rhabdomyosarcoma/ and epithelioid sarcoma
#9381
middle Confidence
Subject:
differential_diagnosis_of_PHE_of_bone
(Diagnostic Process)
→
includes
→
Object:
metastatic_carcinoma
(Metastatic cancer)
Original: differential diagnosis of PHE of bone#includes#osteoblastoma/ epithelioid angiosarcoma/ metastatic carcinoma/ metastatic rhabdomyosarcoma/ and epithelioid sarcoma
#9380
middle Confidence
Subject:
differential_diagnosis_of_PHE_of_bone
(Diagnostic Process)
→
includes
→
Object:
epithelioid_angiosarcoma
(Angiosarcoma)
Original: differential diagnosis of PHE of bone#includes#osteoblastoma/ epithelioid angiosarcoma/ metastatic carcinoma/ metastatic rhabdomyosarcoma/ and epithelioid sarcoma
#9379
middle Confidence
Subject:
differential_diagnosis_of_PHE_of_bone
(Diagnostic Process)
→
includes
→
Object:
osteoblastoma
(Bone tumors)
Original: differential diagnosis of PHE of bone#includes#osteoblastoma/ epithelioid angiosarcoma/ metastatic carcinoma/ metastatic rhabdomyosarcoma/ and epithelioid sarcoma
#9368
middle Confidence
Subject:
Histologic_grading
(Diagnostic Methods)
→
was_done_on
→
Object:
partially_resected_specimens
(Surgical specimens)
Original: Histologic grading#was done on#mastectomy or partially resected specimens
#9367
middle Confidence
Subject:
Histologic_grading
(Diagnostic Methods)
→
was_done_on
→
Object:
mastectomy_specimens
(Surgical specimens)
Original: Histologic grading#was done on#mastectomy or partially resected specimens
#9361
middle Confidence
Subject:
Immunohistochemical_studies
(Detection Technology)
→
showed
→
Object:
positive_staining_of_keratin
(protein)
Original: Immunohistochemical studies#showed#positive staining of neuron-specific enolase (NSE) and keratin
#9360
middle Confidence
Subject:
Immunohistochemical_studies
(Detection Technology)
→
showed
→
Object:
positive_staining_of_NSE
(protein)
Original: Immunohistochemical studies#showed#positive staining of neuron-specific enolase (NSE) and keratin
#9348
middle Confidence
Subject:
Vascular_invasion
(Vascular invasion)
→
is_present_at
→
Object:
diagnosis
(Diagnostic Events)
Original: Vascular invasion#is present#at diagnosis
#9340
middle Confidence
Subject:
epithelioid_rhabdoid_cells
(Tumor cells)
→
have
→
Object:
prominent_nucleoli
(Nuclear structure)
Original: tumor#consisted of#epithelioid rhabdoid cells with vesicular nuclei and prominent nucleoli
#9339
middle Confidence
Subject:
epithelioid_rhabdoid_cells
(Tumor cells)
→
have
→
Object:
vesicular_nuclei
(Nuclear structure)
Original: tumor#consisted of#epithelioid rhabdoid cells with vesicular nuclei and prominent nucleoli
#9338
middle Confidence
Subject:
tumor
(Tumor)
→
consists_of
→
Object:
epithelioid_rhabdoid_cells
(Tumor cells)
Original: tumor#consisted of#epithelioid rhabdoid cells with vesicular nuclei and prominent nucleoli
#9337
middle Confidence
Subject:
tumor
(Tumor)
→
has
→
Object:
prominent_nucleoli
(Nuclear structure)
Original: tumor#had#a pseudo-alveolar pattern with large pleomorphic epithelioid cells and prominent nucleoli
#9336
middle Confidence
Subject:
tumor
(Tumor)
→
has
→
Object:
large_pleomorphic_epithelioid_cells
(Tumor cells)
Original: tumor#had#a pseudo-alveolar pattern with large pleomorphic epithelioid cells and prominent nucleoli
#9335
middle Confidence
Subject:
tumor
(Tumor)
→
has
→
Object:
pseudo-alveolar_pattern
(Organizational Structure)
Original: tumor#had#a pseudo-alveolar pattern with large pleomorphic epithelioid cells and prominent nucleoli
#9334
middle Confidence
Subject:
tumors
(Tumor)
→
show
→
Object:
solid_cell_nests
(Cell structure)
Original: tumors#showed#solid cell nests
#9333
middle Confidence
Subject:
rhabdoid_cells
(Tumor cells)
→
are_composed_of
→
Object:
glassy_eosinophilic_cytoplasm
(Cytoplasmic structure)
Original: rhabdoid cells#are composed of#eccentric nuclei/ prominent nucleoli/ and glassy eosinophilic cytoplasm
#9332
middle Confidence
Subject:
rhabdoid_cells
(Tumor cells)
→
are_composed_of
→
Object:
prominent_nucleoli
(Nuclear structure)
Original: rhabdoid cells#are composed of#eccentric nuclei/ prominent nucleoli/ and glassy eosinophilic cytoplasm
#9331
middle Confidence
Subject:
rhabdoid_cells
(Tumor cells)
→
are_composed_of
→
Object:
eccentric_nuclei
(Nuclear structure)
Original: rhabdoid cells#are composed of#eccentric nuclei/ prominent nucleoli/ and glassy eosinophilic cytoplasm
#9330
middle Confidence
Subject:
large_polygonal_cells
(Tumor cells)
→
have
→
Object:
prominent_nucleoli
(Nuclear structure)
Original: large polygonal cells#had#eccentrically placed irregular/ round-to-ovoid nuclei with occasional prominent nucleoli
#9329
middle Confidence
Subject:
large_polygonal_cells
(Tumor cells)
→
have
→
Object:
round_to_ovoid_nuclei
(Nuclear structure)
Original: large polygonal cells#had#eccentrically placed irregular/ round-to-ovoid nuclei with occasional prominent nucleoli
#9328
middle Confidence
Subject:
large_polygonal_cells
(Tumor cells)
→
have
→
Object:
eccentrically_placed_irregular_nuclei
(Nuclear structure)
Original: large polygonal cells#had#eccentrically placed irregular/ round-to-ovoid nuclei with occasional prominent nucleoli
#9327
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
have
→
Object:
large_nucleoli
(Nuclear structure)
Original: tumor cells#had#large nucleoli
#9282
middle Confidence
Subject:
Tumors
(Tumor)
→
presented_as
→
Object:
necrotizing_mass
(Tumor phenotype)
Original: Tumors#presented as#solitary/ painful/ tender/ necrotizing masses
#9281
middle Confidence
Subject:
Tumors
(Tumor)
→
presented_as
→
Object:
tender_mass
(Tumor phenotype)
Original: Tumors#presented as#solitary/ painful/ tender/ necrotizing masses
#9280
middle Confidence
Subject:
Tumors
(Tumor)
→
presented_as
→
Object:
painful_mass
(Tumor phenotype)
Original: Tumors#presented as#solitary/ painful/ tender/ necrotizing masses
#9279
middle Confidence
Subject:
Tumors
(Tumor)
→
presented_as
→
Object:
solitary_mass
(Tumor phenotype)
Original: Tumors#presented as#solitary/ painful/ tender/ necrotizing masses
#9207
middle Confidence
Subject:
frequency_of_diagnostic_features
(Diagnostic characteristic frequency)
→
is_analyzed_in
→
Object:
prostate_needle_biopsy_specimens
(Tissue samples)
Original: frequency of diagnostic features#is analyzed in#18-gauge prostate needle biopsy specimens
#9206
middle Confidence
Subject:
cytological_criteria
(Cytological criteria)
→
evaluate
→
Object:
cytoplasmic_changes
(Pathological characteristics)
Original: cytological criteria#evaluate#nuclear and nucleolar enlargement/ hyperchromasia/ and cytoplasmic changes
#9205
middle Confidence
Subject:
cytological_criteria
(Cytological criteria)
→
evaluate
→
Object:
hyperchromasia
(Pathological characteristics)
Original: cytological criteria#evaluate#nuclear and nucleolar enlargement/ hyperchromasia/ and cytoplasmic changes
#9204
middle Confidence
Subject:
cytological_criteria
(Cytological criteria)
→
evaluate
→
Object:
nucleolar_enlargement
(Pathological characteristics)
Original: cytological criteria#evaluate#nuclear and nucleolar enlargement/ hyperchromasia/ and cytoplasmic changes
#9203
middle Confidence
Subject:
cytological_criteria
(Cytological criteria)
→
evaluate
→
Object:
nuclear_enlargement
(Pathological characteristics)
Original: cytological criteria#evaluate#nuclear and nucleolar enlargement/ hyperchromasia/ and cytoplasmic changes
#9202
middle Confidence
Subject:
multinucleate_cells
(Multinucleated cells)
→
were_present_in
→
Object:
tumor
(Tumor)
Original: mitotic figures and multinucleate cells#were present in#most fields
#9201
middle Confidence
Subject:
mitotic_figures
(Mitotic figures)
→
were_present_in
→
Object:
tumor
(Tumor)
Original: mitotic figures and multinucleate cells#were present in#most fields
#9200
middle Confidence
Subject:
parameters
(Diagnostic parameters)
→
were_evaluated_in
→
Object:
high-grade_prostatic_intraepithelial_neoplasia
(Pathological characteristics)
Original: parameters#were evaluated in#mimickers of cancer on needle biopsy
#9199
middle Confidence
Subject:
parameters
(Diagnostic parameters)
→
were_evaluated_in
→
Object:
acute_inflammation
(Pathological characteristics)
Original: parameters#were evaluated in#mimickers of cancer on needle biopsy
#9198
middle Confidence
Subject:
parameters
(Diagnostic parameters)
→
were_evaluated_in
→
Object:
adenosis
(Pathological characteristics)
Original: parameters#were evaluated in#mimickers of cancer on needle biopsy
#9197
middle Confidence
Subject:
parameters
(Diagnostic parameters)
→
were_evaluated_in
→
Object:
fully_developed_atrophy
(Pathological characteristics)
Original: parameters#were evaluated in#mimickers of cancer on needle biopsy
#9196
middle Confidence
Subject:
parameters
(Diagnostic parameters)
→
were_evaluated_in
→
Object:
partial_atrophy
(Pathological characteristics)
Original: parameters#were evaluated in#mimickers of cancer on needle biopsy
#9192
middle Confidence
Subject:
prostate_cancers
(Tumor type)
→
were_evaluated_for
→
Object:
presence_of_apoptotic_bodies
(Apoptosis characteristics)
Original: prostate cancers#were evaluated for#number and location of nucleoli/ presence of mitotic figures and apoptotic bodies
#9191
middle Confidence
Subject:
prostate_cancers
(Tumor type)
→
were_evaluated_for
→
Object:
presence_of_mitotic_figures
(Cell division characteristics)
Original: prostate cancers#were evaluated for#number and location of nucleoli/ presence of mitotic figures and apoptotic bodies
#9190
middle Confidence
Subject:
prostate_cancers
(Tumor type)
→
were_evaluated_for
→
Object:
location_of_nucleoli
(Nuclear characteristics)
Original: prostate cancers#were evaluated for#number and location of nucleoli/ presence of mitotic figures and apoptotic bodies
#9189
middle Confidence
Subject:
prostate_cancers
(Tumor type)
→
were_evaluated_for
→
Object:
number_of_nucleoli
(Nuclear characteristics)
Original: prostate cancers#were evaluated for#number and location of nucleoli/ presence of mitotic figures and apoptotic bodies
#9188
middle Confidence
Subject:
metastases
(Tumor type)
→
has_lower_percentage_of
→
Object:
marginated_nucleoli
(Nuclear characteristics)
Original: percentage of marginated nucleoli#was much higher in#glioblastomas than in metastases
#9187
middle Confidence
Subject:
Glioblastomas
(Tumor type)
→
has_higher_percentage_of
→
Object:
marginated_nucleoli
(Nuclear characteristics)
Original: percentage of marginated nucleoli#was much higher in#glioblastomas than in metastases
#9186
middle Confidence
Subject:
anaplastic_astrocytomas
(Tumor type)
→
has
→
Object:
marginated_nucleoli
(Nuclear characteristics)
Original: glioblastomas#had#marginated nucleoli more frequently than anaplastic astrocytomas
#9185
middle Confidence
Subject:
Glioblastomas
(Tumor type)
→
has
→
Object:
marginated_nucleoli
(Nuclear characteristics)
Original: glioblastomas#had#marginated nucleoli more frequently than anaplastic astrocytomas
#9184
middle Confidence
Subject:
patients
(patient)
→
presented_with
→
Object:
skin_lesions
(Clinical symptoms)
Original: patients#presented with#enlargement of superficial lymph nodes/ with skin lesions in 2 patients
#9183
middle Confidence
Subject:
patients
(patient)
→
presented_with
→
Object:
enlargement_of_lymph_nodes
(Clinical symptoms)
Original: patients#presented with#enlargement of superficial lymph nodes/ with skin lesions in 2 patients
#9148
middle Confidence
Subject:
specific_features
(Histological/cytological features)
→
help_avoid
→
Object:
false_negative_interpretation
(Diagnostic Error)
Original: specific features#may help#avoid false-negative interpretation
#9117
middle Confidence
Subject:
smears_from_AIS
(Cytosmear)
→
showed
→
Object:
crowded_sheets
(Densely packed cells)
Original: Smears from AIS#showed#characteristic cytology with glandular rosettes/ palisading/ and crowded sheets
#9116
middle Confidence
Subject:
smears_from_AIS
(Cytosmear)
→
showed
→
Object:
Palisading
(Cell Arrangement)
Original: Smears from AIS#showed#characteristic cytology with glandular rosettes/ palisading/ and crowded sheets
#9115
middle Confidence
Subject:
smears_from_AIS
(Cytosmear)
→
showed
→
Object:
glandular_rosettes
(Glandular structure)
Original: Smears from AIS#showed#characteristic cytology with glandular rosettes/ palisading/ and crowded sheets
#9101
middle Confidence
Subject:
dysplasia
(Disease phenotype)
→
revealed
→
Object:
small_clusters_of_haphazardly_oriented_cells
(Cell morphology phenotype)
Original: dysplasia in BC samples#revealed#small clusters of haphazardly oriented/ mildly pleomorphic cells
#9091
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
suggested
→
Object:
regressing_atypical_histiocytosis
(disease)
Original: cytologic features#suggested#Hodgkin's lymphoma/ lymphomatoid papulosis/ large-cell non-Hodgkin's lymphoma/ regressing atypical histiocytosis
#9090
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
suggested
→
Object:
large-cell_non-Hodgkin's_lymphoma
(disease)
Original: cytologic features#suggested#Hodgkin's lymphoma/ lymphomatoid papulosis/ large-cell non-Hodgkin's lymphoma/ regressing atypical histiocytosis
#9089
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
suggested
→
Object:
lymphomatoid_papulosis
(disease)
Original: cytologic features#suggested#Hodgkin's lymphoma/ lymphomatoid papulosis/ large-cell non-Hodgkin's lymphoma/ regressing atypical histiocytosis
#9088
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
suggested
→
Object:
Hodgkin's_lymphoma
(disease)
Original: cytologic features#suggested#Hodgkin's lymphoma/ lymphomatoid papulosis/ large-cell non-Hodgkin's lymphoma/ regressing atypical histiocytosis
#9085
middle Confidence
Subject:
70-year-old_female
(Patient characteristics)
→
presented_with
→
Object:
mass_occluding_external_auditory_canal
(Clinical symptoms)
Original: A 70-year-old female#presented with#a mass occluding the external auditory canal
#9070
middle Confidence
Subject:
Atypical_spindle_cells
(Cell morphology)
→
shows_positive_marker
→
Object:
CD34
(Cell surface molecules)
Original: Small fragments#contained#atypical spindle cells around slit-like spaces positive for CD31 and CD34
#9069
middle Confidence
Subject:
Atypical_spindle_cells
(Cell morphology)
→
shows_positive_marker
→
Object:
CD31
(Cell surface molecules)
Original: Small fragments#contained#atypical spindle cells around slit-like spaces positive for CD31 and CD34
#9068
middle Confidence
Subject:
KIT
(Receptor tyrosine kinases)
→
shows_strong_immunoreaction_in
→
Object:
Extrapulmonary_small_cell_carcinoma
(Tumor diseases)
Original: Strong immunoreactions#were seen for#CD56 and c-kit
#9067
middle Confidence
Subject:
CD56
(Cell surface molecules)
→
shows_strong_immunoreaction_in
→
Object:
Extrapulmonary_small_cell_carcinoma
(Tumor diseases)
Original: Strong immunoreactions#were seen for#CD56 and c-kit
#9066
middle Confidence
Subject:
Smears
(Cytology samples)
→
revealed
→
Object:
cells_of_intermediate_size_with_round-to-irregular_nuclear_outline
(Cell morphology)
Original: Smears#revealed#cells of intermediate size with round-to-irregular nuclear outline
#9065
middle Confidence
Subject:
FNA_smears
(Diagnostic techniques)
→
demonstrated
→
Object:
low-to-moderate_cellularity
(Cytological characteristics)
Original: FNA smears#demonstrated#low-to-moderate cellularity and tumor cells with eccentrically located nuclei
#9044
middle Confidence
Subject:
small cell carcinoma
(Tumor type)
→
is_distinguished_from
→
Object:
poorly differentiated prostate carcinoma
(Tumor type)
Original: small-cell carcinoma#is distinguished from#poorly differentiated prostate carcinoma by cell size/ finely stippled chromatin/ inconspicuous nucleoli
#9035
middle Confidence
Subject:
recurrent parotid tumor
(Tumor type)
→
presents_with
→
Object:
swelling
(Clinical symptoms)
Original: 55-year-old female#presented with#a swelling in the right parotid region
#9022
middle Confidence
Subject:
multinucleated_giant_cells
(Tumor cells)
→
were_frequently_observed_in
→
Object:
tumor
(Tumor)
Original: Multinucleated giant cells#were frequently observed in#tumor
#9021
middle Confidence
Subject:
ulcerofungating_mass
(Tumor phenotype)
→
was_observed_in
→
Object:
high_body
(Anatomical location)
Original: Ulcerofungating mass#was observed in#high body
#9020
middle Confidence
Subject:
55-year-old_man
(Patient characteristics)
→
presented_with
→
Object:
anemia
(symptom)
Original: A 55-year-old man#presented with#melena and anemia
#9019
middle Confidence
Subject:
55-year-old_man
(Patient characteristics)
→
presented_with
→
Object:
melena
(symptom)
Original: A 55-year-old man#presented with#melena and anemia
#9018
middle Confidence
Subject:
Genotypic_analysis
(Molecular detection technology)
→
reveals
→
Object:
germline_configuration
(Genetic configuration)
Original: Genotypic analysis#revealed#a germline configuration
#9009
middle Confidence
Subject:
resected_mass
(Clinical specimens)
→
was_marked_by
→
Object:
prominent_nucleoli
(Cell nucleolus characteristics)
Original: Resected mass#was marked by#sheets of cells with large nuclei and prominent nucleoli
#9008
middle Confidence
Subject:
resected_mass
(Clinical specimens)
→
was_marked_by
→
Object:
large_nuclei
(Nuclear characteristics)
Original: Resected mass#was marked by#sheets of cells with large nuclei and prominent nucleoli
#9007
middle Confidence
Subject:
resected_mass
(Clinical specimens)
→
was_marked_by
→
Object:
sheets_of_cells
(Cell morphology)
Original: Resected mass#was marked by#sheets of cells with large nuclei and prominent nucleoli
#9006
middle Confidence
Subject:
smears
(Cytosmear)
→
showed
→
Object:
mild_pleomorphism
(Cell morphology)
Original: Smears#showed#predominantly dispersed tumor cells with mild pleomorphism
#9005
middle Confidence
Subject:
smears
(Cytosmear)
→
showed
→
Object:
predominantly_dispersed_tumor_cells
(Cytological characteristics)
Original: Smears#showed#predominantly dispersed tumor cells with mild pleomorphism
#9004
middle Confidence
Subject:
patient
(patient)
→
consulted_for
→
Object:
acute_urinary_retention
(Clinical symptoms)
Original: The patient#consulted hospital for#acute urinary retention
#9003
middle Confidence
Subject:
86-year-old_man
(Patient characteristics)
→
presented_with
→
Object:
enlarged_left_inguinal_lymph_nodes
(Clinical symptoms)
Original: An 86-year-old man#presented with#enlarged left inguinal lymph nodes
#8992
middle Confidence
Subject:
pancreatic_neuroendocrine_tumor
(disease)
→
is_characterized_by
→
Object:
occasional_inconspicuous_nucleoli
(Cell morphology)
Original: pancreatic neuroendocrine tumor#is characterized by#fine/ evenly dispersed nuclear chromatin with occasional inconspicuous nucleoli
#8991
middle Confidence
Subject:
pancreatic_neuroendocrine_tumor
(disease)
→
is_characterized_by
→
Object:
fine_evenly_dispersed_nuclear_chromatin
(Cell morphology)
Original: pancreatic neuroendocrine tumor#is characterized by#fine/ evenly dispersed nuclear chromatin with occasional inconspicuous nucleoli
#8990
middle Confidence
Subject:
solid_undifferentiated_carcinoma
(Histological subtype)
→
is_major_microscopic_pattern_in
→
Object:
prostatic_carcinoma
(disease)
Original: Solid undifferentiated carcinoma#was the major microscopic pattern in#prostatic carcinomas
#8979
middle Confidence
Subject:
Mitosis
(Cytological characteristics)
→
are_found_in
→
Object:
all_cases
(Case characteristics)
Original: Necrosis and/or mitosis#are found#in all cases
#8978
middle Confidence
Subject:
Necrosis
(Cytological characteristics)
→
are_found_in
→
Object:
all_cases
(Case characteristics)
Original: Necrosis and/or mitosis#are found#in all cases
#8976
middle Confidence
Subject:
monolayered_clusters
(Cell morphology)
→
are_present_in
→
Object:
cytological_analysis
(Diagnostic techniques)
Original: Monolayered clusters#are present#in cytological analysis
#8937
middle Confidence
Subject:
morphologic_features
(Pathological morphological features)
→
help_in
→
Object:
detecting_uterine_leiomyomas
(Disease diagnosis)
Original: Morphologic features#help in#detecting HLRCC in uterine leiomyomas
#8936
middle Confidence
Subject:
morphologic_features
(Pathological morphological features)
→
help_in
→
Object:
detecting_HLRCC
(Disease diagnosis)
Original: Morphologic features#help in#detecting HLRCC in uterine leiomyomas
#8928
middle Confidence
Subject:
mediastinal_germ_cell_tumor
(Tumor type)
→
combined
→
Object:
immunohistochemical_profile_of_embryonal_carcinoma
(Immunophenotype)
Original: A mediastinal germ cell tumor#combined#the histologic pattern of seminoma with the immunohistochemical profile of embryonal carcinoma
#8927
middle Confidence
Subject:
mediastinal_germ_cell_tumor
(Tumor type)
→
combined
→
Object:
histologic_pattern_of_seminoma
(Histological morphology)
Original: A mediastinal germ cell tumor#combined#the histologic pattern of seminoma with the immunohistochemical profile of embryonal carcinoma
#8910
middle Confidence
Subject:
tumor_cell
(Tumor cells)
→
is_suspected_of_being
→
Object:
poorly_differentiated_adenocarcinoma_cell
(Tumor cell type)
Original: Tumor cells#were suspected of being#poorly differentiated adenocarcinoma cells
#8878
middle Confidence
Subject:
Tumor_histopathology
(Histological characteristics)
→
consists_of
→
Object:
Cystic_pattern
(Histological morphology)
Original: Histopathology of this tumor#consists of#papillary and cystic patterns
#8877
middle Confidence
Subject:
Tumor_histopathology
(Histological characteristics)
→
consists_of
→
Object:
Papillary_pattern
(Histological morphology)
Original: Histopathology of this tumor#consists of#papillary and cystic patterns
#8861
middle Confidence
Subject:
ACD-associated_RCC
(Tumor)
→
is_characterized_by
→
Object:
oncocytic_cytoplasm
(Histological characteristics)
Original: The tumor#is characterized by#a microcystic pattern and eosinophilic or oncocytic cytoplasm
#8860
middle Confidence
Subject:
ACD-associated_RCC
(Tumor)
→
is_characterized_by
→
Object:
eosinophilic_cytoplasm
(Histological characteristics)
Original: The tumor#is characterized by#a microcystic pattern and eosinophilic or oncocytic cytoplasm
#8859
middle Confidence
Subject:
ACD-associated_RCC
(Tumor)
→
is_characterized_by
→
Object:
microcystic_pattern
(Histological characteristics)
Original: The tumor#is characterized by#a microcystic pattern and eosinophilic or oncocytic cytoplasm
#8858
middle Confidence
Subject:
benign_tumor
(Tumor)
→
is_positive_for
→
Object:
S-100_protein
(Calcium Binding Protein)
Original: The benign tumor#is positive for#vimentin and S-100 protein
#8857
middle Confidence
Subject:
benign_tumor
(Tumor)
→
is_positive_for
→
Object:
vimentin
(Intermediate filament protein)
Original: The benign tumor#is positive for#vimentin and S-100 protein
#8856
middle Confidence
Subject:
intercellular_space
(Intercellular space)
→
is_positive_for
→
Object:
collagen_type_IV
(Collagen)
Original: The intercellular space#is positive for#laminin and collagen type IV
#8855
middle Confidence
Subject:
intercellular_space
(Intercellular space)
→
is_positive_for
→
Object:
laminin
(Extracellular matrix proteins)
Original: The intercellular space#is positive for#laminin and collagen type IV
#8854
middle Confidence
Subject:
malignant_tumor
(Tumor)
→
is_characterized_by
→
Object:
abundant_mitoses
(Histological characteristics)
Original: The malignant tumor#is characterized by#nuclear atypia/ necrosis/ and abundant mitoses
#8853
middle Confidence
Subject:
malignant_tumor
(Tumor)
→
is_characterized_by
→
Object:
Necrosis
(Histological characteristics)
Original: The malignant tumor#is characterized by#nuclear atypia/ necrosis/ and abundant mitoses
#8852
middle Confidence
Subject:
malignant_tumor
(Tumor)
→
is_characterized_by
→
Object:
nuclear_atypia
(Histological characteristics)
Original: The malignant tumor#is characterized by#nuclear atypia/ necrosis/ and abundant mitoses
#8838
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_negative_for
→
Object:
vimentin
(Cytoskeletal proteins)
Original: neoplastic cells#are negative for#vimentin
#8837
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
are_positive_for
→
Object:
cytokeratin
(Cytoskeletal proteins)
Original: neoplastic cells#are positive for#cytokeratin
#8788
middle Confidence
Subject:
aggressive_management
(Treatment strategies)
→
results_in
→
Object:
increased_detection_of_extracranial_metastases
(Diagnosis)
Original: early diagnosis and aggressive management#will result in#increased detection of extracranial metastases
#8787
middle Confidence
Subject:
early_diagnosis
(Diagnostic strategy)
→
results_in
→
Object:
increased_detection_of_extracranial_metastases
(Diagnosis)
Original: early diagnosis and aggressive management#will result in#increased detection of extracranial metastases
#8779
middle Confidence
Subject:
Ki-67
(Cell proliferation markers)
→
expression_level
→
Object:
less_than_1_percent
(Expression level)
Original: Ki-67 labeling#was less than#1%
#8767
middle Confidence
Subject:
Immunohistochemistry
(Immunohistochemistry)
→
avoids
→
Object:
false_positive_diagnosis_of_AC
(Diagnostic Error)
Original: Cytohistology/immunohistochemistry#avoided#false-positive diagnosis of AIS or AC
#8766
middle Confidence
Subject:
Cytohistology
(Cytopathology)
→
avoids
→
Object:
false_positive_diagnosis_of_AIS
(Diagnostic Error)
Original: Cytohistology/immunohistochemistry#avoided#false-positive diagnosis of AIS or AC
#8765
middle Confidence
Subject:
overlapping_atypical_glandular_cell_groups
(Cell morphology)
→
present_on
→
Object:
ThinPrep_slide
(Cytology slides)
Original: Overlapping atypical glandular cell groups#were present#on 2 ThinPrep slides
#8764
middle Confidence
Subject:
oral_squamous_cell_carcinoma
(Solid Tumors)
→
included_in
→
Object:
differential_diagnosis
(Diagnostic Process)
Original: Differential diagnosis#includes#adenoid cystic/ mucoepidermoid/ neuroendocrine/ adenosquamous/ and conventional oral squamous cell carcinoma
#8763
middle Confidence
Subject:
adenosquamous_carcinoma
(Solid Tumors)
→
included_in
→
Object:
differential_diagnosis
(Diagnostic Process)
Original: Differential diagnosis#includes#adenoid cystic/ mucoepidermoid/ neuroendocrine/ adenosquamous/ and conventional oral squamous cell carcinoma
#8762
middle Confidence
Subject:
neuroendocrine_carcinoma
(Solid Tumors)
→
included_in
→
Object:
differential_diagnosis
(Diagnostic Process)
Original: Differential diagnosis#includes#adenoid cystic/ mucoepidermoid/ neuroendocrine/ adenosquamous/ and conventional oral squamous cell carcinoma
#8761
middle Confidence
Subject:
mucoepidermoid_carcinoma
(Solid Tumors)
→
included_in
→
Object:
differential_diagnosis
(Diagnostic Process)
Original: Differential diagnosis#includes#adenoid cystic/ mucoepidermoid/ neuroendocrine/ adenosquamous/ and conventional oral squamous cell carcinoma
#8760
middle Confidence
Subject:
adenoid_cystic_carcinoma
(Solid Tumors)
→
included_in
→
Object:
differential_diagnosis
(Diagnostic Process)
Original: Differential diagnosis#includes#adenoid cystic/ mucoepidermoid/ neuroendocrine/ adenosquamous/ and conventional oral squamous cell carcinoma
#8759
middle Confidence
Subject:
right-sided_pleural_effusion
(Imaging findings)
→
was_shown_on
→
Object:
chest_x-ray
(Imaging tools)
Original: Chest X-ray#showed#mediastinal widening with nonhomogenous opacity mainly in the periphery of right upper and mid zone with right-sided pleural effusion
#8758
middle Confidence
Subject:
nonhomogenous_opacity
(Imaging findings)
→
was_shown_on
→
Object:
chest_x-ray
(Imaging tools)
Original: Chest X-ray#showed#mediastinal widening with nonhomogenous opacity mainly in the periphery of right upper and mid zone with right-sided pleural effusion
#8757
middle Confidence
Subject:
mediastinal_widening
(Imaging findings)
→
was_shown_on
→
Object:
chest_x-ray
(Imaging tools)
Original: Chest X-ray#showed#mediastinal widening with nonhomogenous opacity mainly in the periphery of right upper and mid zone with right-sided pleural effusion
#8745
middle Confidence
Subject:
FNA_biopsy
(Cytology)
→
combined_with
→
Object:
ultrastructural_studies
(Ultrastructural analysis)
Original: FNA biopsy#combined with#immunocytochemical and ultrastructural studies
#8744
middle Confidence
Subject:
FNA_biopsy
(Cytology)
→
combined_with
→
Object:
immunocytochemical_studies
(Immunocytochemical analysis)
Original: FNA biopsy#combined with#immunocytochemical and ultrastructural studies
#8743
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
reacted_negatively_with
→
Object:
CD68
(Macrophage markers)
Original: Tumor cells#reacted negatively with#AE1/ cytokeratin19/ carcinoembryonic antigen/ alpha-fetoprotein/ Factor VIII/ CD31/ CD68
#8742
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
reacted_negatively_with
→
Object:
CD31
(Endothelial cell markers)
Original: Tumor cells#reacted negatively with#AE1/ cytokeratin19/ carcinoembryonic antigen/ alpha-fetoprotein/ Factor VIII/ CD31/ CD68
#8741
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
reacted_negatively_with
→
Object:
Factor_VIII
(Coagulation factors)
Original: Tumor cells#reacted negatively with#AE1/ cytokeratin19/ carcinoembryonic antigen/ alpha-fetoprotein/ Factor VIII/ CD31/ CD68
#8740
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
reacted_negatively_with
→
Object:
alpha_fetoprotein
(Tumor markers)
Original: Tumor cells#reacted negatively with#AE1/ cytokeratin19/ carcinoembryonic antigen/ alpha-fetoprotein/ Factor VIII/ CD31/ CD68
#8739
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
reacted_negatively_with
→
Object:
carcinoembryonic_antigen
(Tumor markers)
Original: Tumor cells#reacted negatively with#AE1/ cytokeratin19/ carcinoembryonic antigen/ alpha-fetoprotein/ Factor VIII/ CD31/ CD68
#8738
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
reacted_negatively_with
→
Object:
cytokeratin19
(Cytokeratin)
Original: Tumor cells#reacted negatively with#AE1/ cytokeratin19/ carcinoembryonic antigen/ alpha-fetoprotein/ Factor VIII/ CD31/ CD68
#8737
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
reacted_negatively_with
→
Object:
AE1
(Cytokeratin Antibodies)
Original: Tumor cells#reacted negatively with#AE1/ cytokeratin19/ carcinoembryonic antigen/ alpha-fetoprotein/ Factor VIII/ CD31/ CD68
#8736
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
reacted_positively_with
→
Object:
Vimentin
(Cytoskeletal proteins)
Original: Tumor cells#reacted positively with#AE3 and Vimentin
#8735
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
reacted_positively_with
→
Object:
AE3
(Cytokeratin Antibodies)
Original: Tumor cells#reacted positively with#AE3 and Vimentin
#8720
middle Confidence
Subject:
Cultures
(Cell culture)
→
produced
→
Object:
carbohydrate_antigen_125
(Tumor markers)
Original: Cultures#produced#carcinoembryonic antigen (27.4 ng/mL)/ carbohydrate antigen 19-9 (210 U/mL)/ carbohydrate antigen 125 (526 U/mL)
#8719
middle Confidence
Subject:
Cultures
(Cell culture)
→
produced
→
Object:
carbohydrate_antigen_19-9
(Tumor markers)
Original: Cultures#produced#carcinoembryonic antigen (27.4 ng/mL)/ carbohydrate antigen 19-9 (210 U/mL)/ carbohydrate antigen 125 (526 U/mL)
#8718
middle Confidence
Subject:
Cultures
(Cell culture)
→
produced
→
Object:
carcinoembryonic_antigen
(Tumor markers)
Original: Cultures#produced#carcinoembryonic antigen (27.4 ng/mL)/ carbohydrate antigen 19-9 (210 U/mL)/ carbohydrate antigen 125 (526 U/mL)
#8717
middle Confidence
Subject:
Pleomorphic_cells
(Cell Type)
→
showed
→
Object:
strong_immunoreactivity_for_HMB-45
(Immune markers)
Original: Pleomorphic cells#showed#strong immunoreactivity for Melan-A and HMB-45
#8716
middle Confidence
Subject:
Pleomorphic_cells
(Cell Type)
→
showed
→
Object:
strong_immunoreactivity_for_Melan-A
(Immune markers)
Original: Pleomorphic cells#showed#strong immunoreactivity for Melan-A and HMB-45
#8688
middle Confidence
Subject:
diagnostic material
(Diagnostic Materials)
→
comes_from
→
Object:
cytological samples in lung cancer patients
(Sample Type)
Original: diagnostic material#often comes from#biopsy or cytological samples in lung cancer patients
#8687
middle Confidence
Subject:
diagnostic material
(Diagnostic Materials)
→
comes_from
→
Object:
biopsy samples in lung cancer patients
(Sample Type)
Original: diagnostic material#often comes from#biopsy or cytological samples in lung cancer patients
#8684
middle Confidence
Subject:
diffuse large B-cell lymphoma
(Tumor type)
→
is_diagnosed_in
→
Object:
patient with Crohn's disease symptoms
(Patient characteristics)
Original: diffuse large B-cell lymphoma#is diagnosed in#a patient with Crohn's disease symptoms
#8683
middle Confidence
Subject:
tumors with Gleason score lower than 6
(Tumor grade)
→
causes
→
Object:
greater diagnostic problems
(Difficulty in diagnosis)
Original: tumors with Gleason score lower than 6#cause#greater diagnostic problems
#8671
middle Confidence
Subject:
Pituitary samples
(Tissue samples)
→
showed
→
Object:
p53 immunolabelling
(Protein markers)
Original: Pituitary samples#showed#brisk mitotic activity/ high Ki-67/ and p53 immunolabelling
#8670
middle Confidence
Subject:
Pituitary samples
(Tissue samples)
→
showed
→
Object:
high Ki-67
(Protein markers)
Original: Pituitary samples#showed#brisk mitotic activity/ high Ki-67/ and p53 immunolabelling
#8668
middle Confidence
Subject:
Computed_tomography_scan
(Medical imaging technology)
→
revealed
→
Object:
hypervascular_masses_on_anterior_peritoneum
(Imaging findings)
Original: Computed tomography scan#revealed#multiple hypervascular masses on the liver surface/ pelvic cavity/ and anterior peritoneum
#8667
middle Confidence
Subject:
Computed_tomography_scan
(Medical imaging technology)
→
revealed
→
Object:
hypervascular_masses_on_pelvic_cavity
(Imaging findings)
Original: Computed tomography scan#revealed#multiple hypervascular masses on the liver surface/ pelvic cavity/ and anterior peritoneum
#8666
middle Confidence
Subject:
Computed_tomography_scan
(Medical imaging technology)
→
revealed
→
Object:
hypervascular_masses_on_liver_surface
(Imaging findings)
Original: Computed tomography scan#revealed#multiple hypervascular masses on the liver surface/ pelvic cavity/ and anterior peritoneum
#8649
middle Confidence
Subject:
tumor
(Tumor)
→
shows
→
Object:
diffuse_arrangement_of_large_epithelial_cells
(Tumor cell arrangement characteristics)
Original: tumor#shows#a diffuse arrangement of large/ closely packed epithelial cells
#8581
middle Confidence
Subject:
Endometrial_hyperplasias
(Disease phenotype)
→
presented
→
Object:
greatest_difficulties_in_interpretation
(Difficulties in diagnosis)
Original: Endometrial hyperplasias#presented#greatest difficulties in interpretation
#8553
middle Confidence
Subject:
PAH
(Histopathological phenotype)
→
is_distinct_from
→
Object:
simple_atrophy
(Histopathological phenotype)
Original: PAH#is distinct from#simple atrophy
#8524
middle Confidence
Subject:
colloid_nodule
(Benign nodules)
→
shares_morphologic_features_with
→
Object:
follicular_variant_of_papillary_carcinoma
(Malignant tumors)
Original: The cytologic differential diagnosis of colloid nodule (CN) and follicular variant of papillary carcinoma (FVPC)#is#difficult with common morphologic features
#8510
middle Confidence
Subject:
FNA_of_mass
(Cytology samples)
→
shows
→
Object:
low_to_hypercellular_smears
(Cytological characteristics)
Original: FNA of the mass#showed#low to hypercellular smears composed of some amorphous pink to bluish material
#8509
middle Confidence
Subject:
MO
(disease)
→
is_suspected_by
→
Object:
soft_tissue_mass
(Clinical symptoms)
Original: Nine patients#presented with#a chief complaint of soft tissue mass with clinically suspected MO
#8508
middle Confidence
Subject:
cytologic_examination
(Diagnostic Methods)
→
reveals
→
Object:
loosely_cohesive_clusters_of_large_cells
(Cell morphology)
Original: Cytologic examination#revealed#loosely cohesive clusters of large cells possessing round to oval nuclei with no or minimal atypia
#8507
middle Confidence
Subject:
FNA_specimen
(Cytology samples)
→
is_compared_with
→
Object:
FNA_specimen
(Cytology samples)
Original: Thirty FNA specimens of histologically proven TCV#were compared with#32 FNA specimens of histologically proven UV-PTC
#8506
middle Confidence
Subject:
distinct_cell_borders
(Cell morphology)
→
are_present_in
→
Object:
adenocarcinoma
(Tumor type)
Original: distinct cell borders#are present in#9 cases
#8505
middle Confidence
Subject:
epithelioid_cells
(Cell Type)
→
aggregated_in
→
Object:
solid_nests
(Organizational Structure)
Original: neoplasm#shows#epithelioid cells with prominent nucleoli aggregated in solid nests
#8504
middle Confidence
Subject:
epithelioid_cells
(Cell Type)
→
show
→
Object:
prominent_nucleoli
(Nuclear characteristics)
Original: neoplasm#shows#epithelioid cells with prominent nucleoli aggregated in solid nests
#8496
middle Confidence
Subject:
Nipple_scraping_cytological_smear
(Cytology specimens)
→
contains
→
Object:
single_epithelial_cells
(Single epithelial cell)
Original: Nipple scraping cytological smears#are characterised by#a bloody background with epithelial cells arranged in clusters or singularly
#8495
middle Confidence
Subject:
Nipple_scraping_cytological_smear
(Cytology specimens)
→
contains
→
Object:
epithelial_cell_clusters
(Epithelial cell mass)
Original: Nipple scraping cytological smears#are characterised by#a bloody background with epithelial cells arranged in clusters or singularly
#8494
middle Confidence
Subject:
Nipple_scraping_cytological_smear
(Cytology specimens)
→
characterized_by
→
Object:
bloody_background
(Bloody Background)
Original: Nipple scraping cytological smears#are characterised by#a bloody background with epithelial cells arranged in clusters or singularly
#8486
middle Confidence
Subject:
Cytology
(Cytological characteristics)
→
is_described_for
→
Object:
poorly_differentiated_hemangiosarcoma
(Tumor type)
Original: Cytology#is described for#well-differentiated and poorly differentiated hemangiosarcoma
#8485
middle Confidence
Subject:
Cytology
(Cytological characteristics)
→
is_described_for
→
Object:
well-differentiated_hemangiosarcoma
(Tumor type)
Original: Cytology#is described for#well-differentiated and poorly differentiated hemangiosarcoma
#8430
middle Confidence
Subject:
villous_adenoma_of_ampullary_region
(Tumor tissue)
→
displays
→
Object:
distinctive_morphologic_pattern
(Morphological characteristics)
Original: villous adenoma of the ampullary region#has#distinctive morphologic pattern
#8429
middle Confidence
Subject:
alpha-fetoprotein
(Tumor markers)
→
is_positive_in
→
Object:
tumor_cells
(Tumor cells)
Original: Cells#were positive for#alpha-fetoprotein
#8416
middle Confidence
Subject:
histology
(Histology)
→
reveals
→
Object:
ultrastructural_changes
(Cell ultrastructure)
Original: Histology#reveals#findings corresponding to cytologic changes
#8415
middle Confidence
Subject:
histology
(Histology)
→
reveals
→
Object:
cytologic_changes
(Cell phenotype)
Original: Histology#reveals#findings corresponding to cytologic changes
#8320
middle Confidence
Subject:
Malignant_esophageal_epithelial_tumor
(Malignant esophageal epithelial tumor)
→
lacks
→
Object:
definite_microscopic_features_of_neuroendocrine_differentiation
(Histological characteristics)
Original: Malignant esophageal epithelial tumor#lacks#definite microscopic features of squamous/ glandular/ or neuroendocrine differentiation
#8319
middle Confidence
Subject:
Malignant_esophageal_epithelial_tumor
(Malignant esophageal epithelial tumor)
→
lacks
→
Object:
definite_microscopic_features_of_glandular_differentiation
(Histological characteristics)
Original: Malignant esophageal epithelial tumor#lacks#definite microscopic features of squamous/ glandular/ or neuroendocrine differentiation
#8318
middle Confidence
Subject:
Malignant_esophageal_epithelial_tumor
(Malignant esophageal epithelial tumor)
→
lacks
→
Object:
definite_microscopic_features_of_squamous_differentiation
(Histological characteristics)
Original: Malignant esophageal epithelial tumor#lacks#definite microscopic features of squamous/ glandular/ or neuroendocrine differentiation
#8317
middle Confidence
Subject:
Patient
(patient)
→
was_diagnosed_with
→
Object:
high-grade_infiltrating_ductal_carcinoma
(Breast cancer subtypes)
Original: One patient#was diagnosed with#medullary carcinoma/ while another had high-grade infiltrating ductal carcinoma
#8316
middle Confidence
Subject:
Patient
(patient)
→
was_diagnosed_with
→
Object:
medullary_carcinoma
(Breast cancer subtypes)
Original: One patient#was diagnosed with#medullary carcinoma/ while another had high-grade infiltrating ductal carcinoma
#8315
middle Confidence
Subject:
Latent_membrane_protein
(Membrane Protein)
→
is_positive_in
→
Object:
RS-like_immunoblastic_large_cells
(Tumor cell subtype)
Original: Latent membrane protein#was positive in#a minority of RS-like immunoblastic large cells
#8314
middle Confidence
Subject:
Uterine_cellular_samples
(Uterine cell sample)
→
provide_information_regarding
→
Object:
extent_of_neoplasm
(Tumor extent)
Original: Malignancy in uterine cellular samples#provides information regarding#the extent of the neoplasm
#8226
middle Confidence
Subject:
granulocytic_sarcoma
(Myeloid sarcoma)
→
was_diagnosed_as
→
Object:
final_diagnosis
(Diagnosis conclusion)
Original: granulocytic sarcoma#was diagnosed as#final diagnosis
#8221
middle Confidence
Subject:
disc_herniation
(Herniated disc)
→
was_suspected_at
→
Object:
L5
(Anatomical location)
Original: disc herniation#was suspected at#L5 and S
#8187
middle Confidence
Subject:
initial_immunohistochemical_workup
(Experimental testing)
→
was_negative_for
→
Object:
p63
(Transcription Factors)
Original: initial immunohistochemical workup#was negative for#cytokeratin (AE1/AE3)/ EMA/ p63
#8186
middle Confidence
Subject:
initial_immunohistochemical_workup
(Experimental testing)
→
was_negative_for
→
Object:
EMA
(Epithelial membrane antigen)
Original: initial immunohistochemical workup#was negative for#cytokeratin (AE1/AE3)/ EMA/ p63
#8185
middle Confidence
Subject:
initial_immunohistochemical_workup
(Experimental testing)
→
was_negative_for
→
Object:
cytokeratin_AE1_AE3
(Cytokeratin)
Original: initial immunohistochemical workup#was negative for#cytokeratin (AE1/AE3)/ EMA/ p63
#8184
middle Confidence
Subject:
initial_immunohistochemical_workup
(Experimental testing)
→
showed
→
Object:
CD34_positivity
(Protein expression status)
Original: initial immunohistochemical workup#showed#CD34 positivity
#8183
middle Confidence
Subject:
cytology_slides
(Cytology slides)
→
were_prepared_using
→
Object:
liquid_based_preparation
(Preparation method)
Original: cytology slides#were prepared using#conventional smear and liquid-based preparations
#8182
middle Confidence
Subject:
cytology_slides
(Cytology slides)
→
were_prepared_using
→
Object:
conventional_smear
(Preparation method)
Original: cytology slides#were prepared using#conventional smear and liquid-based preparations
#8181
middle Confidence
Subject:
cytological_samples
(Cytology samples)
→
were_obtained_from
→
Object:
patients_with_GEA
(Patient population)
Original: 18 cytological samples#were obtained from#14 patients with GEA
#8174
middle Confidence
Subject:
H-FLAC
(Tumor subtype)
→
shows
→
Object:
prominent_nucleoli
(Cell nucleolus characteristics)
Original: H-FLAC#was distinguished from#L-FLAC by disorganized glands/ large vesicular nuclei/ prominent nucleoli/ and overexpression of p53 protein
#8173
middle Confidence
Subject:
H-FLAC
(Tumor subtype)
→
shows
→
Object:
large_vesicular_nuclei
(Nuclear characteristics)
Original: H-FLAC#was distinguished from#L-FLAC by disorganized glands/ large vesicular nuclei/ prominent nucleoli/ and overexpression of p53 protein
#8172
middle Confidence
Subject:
H-FLAC
(Tumor subtype)
→
shows
→
Object:
disorganized_glands
(Histological characteristics)
Original: H-FLAC#was distinguished from#L-FLAC by disorganized glands/ large vesicular nuclei/ prominent nucleoli/ and overexpression of p53 protein
#8171
middle Confidence
Subject:
L-FLAC
(Tumor subtype)
→
shows
→
Object:
neuroendocrine_differentiation
(Neuroendocrine differentiation)
Original: H-FLAC and L-FLAC#have#complex glandular structures resembling fetal lung and neuroendocrine differentiation
#8170
middle Confidence
Subject:
H-FLAC
(Tumor subtype)
→
shows
→
Object:
neuroendocrine_differentiation
(Neuroendocrine differentiation)
Original: H-FLAC and L-FLAC#have#complex glandular structures resembling fetal lung and neuroendocrine differentiation
#8169
middle Confidence
Subject:
L-FLAC
(Tumor subtype)
→
shows
→
Object:
complex_glandular_structures
(Histological characteristics)
Original: H-FLAC and L-FLAC#have#complex glandular structures resembling fetal lung and neuroendocrine differentiation
#8168
middle Confidence
Subject:
H-FLAC
(Tumor subtype)
→
shows
→
Object:
complex_glandular_structures
(Histological characteristics)
Original: H-FLAC and L-FLAC#have#complex glandular structures resembling fetal lung and neuroendocrine differentiation
#8165
middle Confidence
Subject:
FNA_cytology
(Detection Technology)
→
revealed
→
Object:
tumor_giant_cells
(Cell morphology)
Original: FNA cytology#revealed#pleomorphic oval cells with prominent nucleoli/ spindle cells/ tumor giant cells/ and a chondromyxoid background
#8164
middle Confidence
Subject:
FNA_cytology
(Detection Technology)
→
revealed
→
Object:
spindle_cells
(Cell morphology)
Original: FNA cytology#revealed#pleomorphic oval cells with prominent nucleoli/ spindle cells/ tumor giant cells/ and a chondromyxoid background
#8163
middle Confidence
Subject:
FNA_cytology
(Detection Technology)
→
revealed
→
Object:
pleomorphic_oval_cells
(Cell morphology)
Original: FNA cytology#revealed#pleomorphic oval cells with prominent nucleoli/ spindle cells/ tumor giant cells/ and a chondromyxoid background
#8162
middle Confidence
Subject:
cytopathology_of_pericardial_effusion
(Cytological analysis)
→
showed
→
Object:
monotonous_cells
(Cell morphology)
Original: Cytopathology of pericardial effusion#showed#monotonous cells with oval-spindle vesicular nuclei and inconspicuous nucleoli
#8161
middle Confidence
Subject:
stromal_proliferation
(Cellular Processes)
→
features
→
Object:
medium_size_cells
(Cell morphology)
Original: Microscopy#revealed#stromal proliferation with medium size cells/ monomorphic shape/ and prominent nucleoli
#8160
middle Confidence
Subject:
microscopy
(Detection Technology)
→
revealed
→
Object:
stromal_proliferation
(Cellular Processes)
Original: Microscopy#revealed#stromal proliferation with medium size cells/ monomorphic shape/ and prominent nucleoli
#8135
middle Confidence
Subject:
Morphological_analysis
(Morphological analysis)
→
was_performed_on
→
Object:
yolk_sac_tumor_patients
(patient)
Original: Morphological analysis#was performed on#imprint cytology and histology in yolk sac tumor patients
#8131
middle Confidence
Subject:
Neoplastic_follicular_cell_nuclei
(Nucleus)
→
were_divided_into
→
Object:
hyperlobation
(Nuclear structure)
Original: Neoplastic follicular cell nuclei#were divided into#grooves/ pseudoinclusions/ and hyperlobation consistent with papillary thyroid carcinoma
#8130
middle Confidence
Subject:
Neoplastic_follicular_cell_nuclei
(Nucleus)
→
were_divided_into
→
Object:
pseudoinclusions
(Nuclear structure)
Original: Neoplastic follicular cell nuclei#were divided into#grooves/ pseudoinclusions/ and hyperlobation consistent with papillary thyroid carcinoma
#8129
middle Confidence
Subject:
Neoplastic_follicular_cell_nuclei
(Nucleus)
→
were_divided_into
→
Object:
grooves
(Nuclear structure)
Original: Neoplastic follicular cell nuclei#were divided into#grooves/ pseudoinclusions/ and hyperlobation consistent with papillary thyroid carcinoma
#8073
middle Confidence
Subject:
RM
(Cell Type)
→
are_identified_as
→
Object:
groups_of_small_cells_with_minimal_nuclear_atypia_overlap_and_irregular_borders
(Cell phenotype)
Original: RM#are identified as#groups of small cells with minimal nuclear atypia/ overlap/ and irregular borders
#8072
middle Confidence
Subject:
nuclear-to-cytoplasmic_ratio
(Morphological characteristics)
→
are_evaluated_in
→
Object:
peritoneal_fluids
(Biological samples)
Original: papillae presence and size/ intercellular windows/ and nuclear-to-cytoplasmic ratios#are evaluated in#peritoneal fluids
#8071
middle Confidence
Subject:
intercellular_windows
(Morphological characteristics)
→
are_evaluated_in
→
Object:
peritoneal_fluids
(Biological samples)
Original: papillae presence and size/ intercellular windows/ and nuclear-to-cytoplasmic ratios#are evaluated in#peritoneal fluids
#8070
middle Confidence
Subject:
papillae_presence_and_size
(Morphological characteristics)
→
are_evaluated_in
→
Object:
peritoneal_fluids
(Biological samples)
Original: papillae presence and size/ intercellular windows/ and nuclear-to-cytoplasmic ratios#are evaluated in#peritoneal fluids
#8064
middle Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
must_include
→
Object:
cutaneous_metastasis_of_lymphoepithelioma
(Metastatic tumors)
Original: Differential diagnosis#must include#malignant lymphomas/ Merkel cell tumour/ squamous cell carcinoma/ cutaneous metastasis of lymphoepithelioma
#8063
middle Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
must_include
→
Object:
squamous_cell_carcinoma
(Tumor diseases)
Original: Differential diagnosis#must include#malignant lymphomas/ Merkel cell tumour/ squamous cell carcinoma/ cutaneous metastasis of lymphoepithelioma
#8062
middle Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
must_include
→
Object:
Merkel_cell_tumour
(Tumor diseases)
Original: Differential diagnosis#must include#malignant lymphomas/ Merkel cell tumour/ squamous cell carcinoma/ cutaneous metastasis of lymphoepithelioma
#8061
middle Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
must_include
→
Object:
malignant_lymphoma
(Tumor diseases)
Original: Differential diagnosis#must include#malignant lymphomas/ Merkel cell tumour/ squamous cell carcinoma/ cutaneous metastasis of lymphoepithelioma
#8052
middle Confidence
Subject:
AgNOR_clusters
(Nuclear structure)
→
are_absent_in
→
Object:
carcinomas
(Malignant tumors)
Original: AgNOR clusters#are centrally located in#colloid goitre but absent in carcinomas
#8051
middle Confidence
Subject:
AgNOR_clusters
(Nuclear structure)
→
are_centrally_located_in
→
Object:
colloid_goitre
(Benign thyroid disease)
Original: AgNOR clusters#are centrally located in#colloid goitre but absent in carcinomas
#8050
middle Confidence
Subject:
histologically_confirmed_aspirated_samples
(Histological samples)
→
are_classified_into
→
Object:
thyroid_lesions
(disease)
Original: histologically confirmed aspirated samples#are classified into#thyroid lesions cytologically
#8005
middle Confidence
Subject:
Liver_biopsy
(Diagnostic Methods)
→
confirms
→
Object:
FNA_diagnosis
(Diagnosis conclusion)
Original: Liver biopsy#was consistent with#the FNA diagnosis
#8004
middle Confidence
Subject:
Histologic_study
(Diagnostic Methods)
→
supports
→
Object:
Hepatic_YST_diagnosis
(Diagnosis conclusion)
Original: Diagnosis of hepatic YST#was made by#cytologic/ histologic/ and immunohistochemical studies
#8003
middle Confidence
Subject:
Cytologic_study
(Diagnostic Methods)
→
supports
→
Object:
Hepatic_YST_diagnosis
(Diagnosis conclusion)
Original: Diagnosis of hepatic YST#was made by#cytologic/ histologic/ and immunohistochemical studies
#8002
middle Confidence
Subject:
abdominal_ultrasound
(Imaging tests)
→
raised
→
Object:
suspicion_of_malignancy_involving_descending_colon
(Diagnosis conclusion)
Original: Abdominal US and CT#raised#the suspicion of a malignancy involving the descending colon
#8000
middle Confidence
Subject:
leiomyosarcoma
(Tumor subtype)
→
characterized_by
→
Object:
invasion_to_adjacent_normal_tissue
(Tissue invasion)
Original: leiomyosarcoma#characterized by#cellular atypia/ more mitotic cells/ and invasion to adjacent normal tissue
#7999
middle Confidence
Subject:
leiomyosarcoma
(Tumor subtype)
→
characterized_by
→
Object:
increased_mitotic_cells
(Cell characteristics)
Original: leiomyosarcoma#characterized by#cellular atypia/ more mitotic cells/ and invasion to adjacent normal tissue
#7998
middle Confidence
Subject:
leiomyosarcoma
(Tumor subtype)
→
characterized_by
→
Object:
cellular_atypia
(Cell characteristics)
Original: leiomyosarcoma#characterized by#cellular atypia/ more mitotic cells/ and invasion to adjacent normal tissue
#7941
middle Confidence
Subject:
squamous_cell_carcinoma_of_thymus
(Tumor type)
→
should_be_separated_from
→
Object:
ordinary_thymoma_of_epithelial_type
(Tumor type)
Original: Squamous cell carcinoma of the thymus#should be separated from#ordinary thymoma of the epithelial type
#7940
middle Confidence
Subject:
FNAC_smears
(Cytology samples)
→
are_derived_from
→
Object:
grade_1_breast_carcinoma
(Tumor grade)
Original: FNAC smears#are derived from#494 histologically confirmed grade 1 breast carcinomas
#7926
middle Confidence
Subject:
HLRCC_tumors
(Tumor)
→
are_characterized_by
→
Object:
large_nucleus_with_prominent_nucleolus_and_clear_halo
(Nuclear phenotype)
Original: HLRCC tumors#are characterized by#large nucleus with prominent nucleolus surrounded by clear halo
#7924
middle Confidence
Subject:
HLRCC_syndrome
(Hereditary cancer syndromes)
→
is_characterized_by
→
Object:
renal_tumors
(Kidney tumors)
Original: HLRCC syndrome#is characterized by#cutaneous and uterine leiomyomas and renal tumors
#7923
middle Confidence
Subject:
HLRCC_syndrome
(Hereditary cancer syndromes)
→
is_characterized_by
→
Object:
uterine_leiomyomas
(Uterine leiomyoma)
Original: HLRCC syndrome#is characterized by#cutaneous and uterine leiomyomas and renal tumors
#7922
middle Confidence
Subject:
HLRCC_syndrome
(Hereditary cancer syndromes)
→
is_characterized_by
→
Object:
cutaneous_leiomyomas
(Skin leiomyoma)
Original: HLRCC syndrome#is characterized by#cutaneous and uterine leiomyomas and renal tumors
#7834
middle Confidence
Subject:
Differentiation_of_ALK+LBCL
(Tumor classification)
→
distinguishes_from
→
Object:
other_lymphoma_subtypes
(disease)
Original: Differentiation of ALK+LBCL#from#metastatic carcinoma and other lymphoma subtypes
#7833
middle Confidence
Subject:
Differentiation_of_ALK+LBCL
(Tumor classification)
→
distinguishes_from
→
Object:
metastatic_carcinoma
(disease)
Original: Differentiation of ALK+LBCL#from#metastatic carcinoma and other lymphoma subtypes
#7832
middle Confidence
Subject:
Aspiration_cytology_findings
(Cytological manifestations)
→
observed_in
→
Object:
ALK-positive_large_B-cell_lymphoma
(disease)
Original: Aspiration cytology findings#were observed in#a case of ALK-positive large B-cell lymphoma
#7831
middle Confidence
Subject:
clinical_data
(Clinical Data)
→
supports
→
Object:
Pemphigus_vulgaris
(disease)
Original: Cytological findings#can be correlated with#clinical data for suspected PV diagnosis
#7830
middle Confidence
Subject:
Cytological_findings
(Cytological manifestations)
→
correlates_with
→
Object:
clinical_data
(Clinical Data)
Original: Cytological findings#can be correlated with#clinical data for suspected PV diagnosis
#7803
middle Confidence
Subject:
bladder_washings
(Pathological samples)
→
shows
→
Object:
scattered_dyscohesive_cells_with_plasmacytoid_appearance
(Cell morphology)
Original: Bladder washings#showed#scattered dyscohesive cells with plasmacytoid appearance
#7802
middle Confidence
Subject:
AMM_case
(Case)
→
displays
→
Object:
intranuclear_cytoplasmic_inclusions
(Cell morphology)
Original: The AMM case#displayed#numerous mitotic figures and intranuclear cytoplasmic inclusions
#7801
middle Confidence
Subject:
AMM_case
(Case)
→
displays
→
Object:
numerous_mitotic_figures
(Cell division phenotype)
Original: The AMM case#displayed#numerous mitotic figures and intranuclear cytoplasmic inclusions
#7796
middle Confidence
Subject:
BCH_diagnosis
(Clinical diagnosis)
→
is_aided_by
→
Object:
pseudocribriform_glands
(Histological morphology)
Original: BCH diagnosis#is aided by#solid nests and pseudocribriform glands
#7795
middle Confidence
Subject:
BCH_diagnosis
(Clinical diagnosis)
→
is_aided_by
→
Object:
solid_nests
(Histological morphology)
Original: BCH diagnosis#is aided by#solid nests and pseudocribriform glands
#7792
middle Confidence
Subject:
basal_cell_hyperplasia
(Histopathological features)
→
is_recognized_in
→
Object:
transurethral_resection_specimens
(Tissue samples)
Original: BCH#is recognized in#transurethral resection specimens
#7791
middle Confidence
Subject:
peritoneal_fluids
(Body fluid samples)
→
contained
→
Object:
neoplastic_cells
(Tumor cells)
Original: Peritoneal fluids#contained#neoplastic cells
#7688
middle Confidence
Subject:
PBL
(Tumor)
→
should_be_included_in
→
Object:
differential_diagnosis_of_oral_mass_lesions
(Differential diagnosis of diseases)
Original: PBL#should be included in#the differential diagnosis of oral mass lesions
#7687
middle Confidence
Subject:
Histopathological_and_immunohistochemical_characteristics
(Pathological and immunohistochemical characteristics)
→
diagnosed_as
→
Object:
PBL
(Tumor)
Original: Histopathological and immunohistochemical characteristics#diagnosed as#PBL
#7668
middle Confidence
Subject:
anisonucleosis
(Nuclear characteristics)
→
shows_association_with
→
Object:
diagnosis_of_CIS
(Diagnostic behavior)
Original: chromatin clumping and anisonucleosis#showed#association with diagnosis of CIS
#7667
middle Confidence
Subject:
chromatin_clumping
(Nuclear characteristics)
→
shows_association_with
→
Object:
diagnosis_of_CIS
(Diagnostic behavior)
Original: chromatin clumping and anisonucleosis#showed#association with diagnosis of CIS
#7666
middle Confidence
Subject:
Cytotechnologist
(Technical Staff)
→
screens
→
Object:
cytopathologic_signs_on_slides
(Cytopathological features)
Original: cytotechnologist#screened#slides for cytopathologic signs
#7661
middle Confidence
Subject:
tumor
(Tumor)
→
has
→
Object:
rhabdoid_features
(Cell morphology)
Original: tumor#has#rhabdoid features
#7655
middle Confidence
Subject:
biopsy
(Biopsy)
→
showed
→
Object:
cohesive_clusters_of_cells_with_prominent_nucleoli
(Cell structure)
Original: biopsy#showed#lymphoid cells and cohesive clusters of cells with prominent nucleoli
#7654
middle Confidence
Subject:
biopsy
(Biopsy)
→
showed
→
Object:
lymphoid_cells
(Immune cells)
Original: biopsy#showed#lymphoid cells and cohesive clusters of cells with prominent nucleoli
#7621
middle Confidence
Subject:
colorectal_mixed_hyperplastic_adenomatous_polyps
(Mixed colorectal hyperplastic adenomatous polyps)
→
exhibited
→
Object:
architectural_features_of_hyperplastic_polyp
(Tissue morphology)
Original: colorectal mixed hyperplastic adenomatous polyps#exhibited#architectural features of hyperplastic polyp
#7620
middle Confidence
Subject:
atypical_cells
(Cell Type)
→
are_characterized_by
→
Object:
prominent_nucleoli
(Cell nucleolus characteristics)
Original: atypical cells#are characterized by#vesicular nuclei and prominent nucleoli
#7619
middle Confidence
Subject:
atypical_cells
(Cell Type)
→
are_characterized_by
→
Object:
vesicular_nuclei
(Nuclear characteristics)
Original: atypical cells#are characterized by#vesicular nuclei and prominent nucleoli
#7618
middle Confidence
Subject:
cuboidal_cells
(Cell Type)
→
show
→
Object:
prominent_nucleoli
(Cell nucleolus characteristics)
Original: cuboidal cells#show#cytologic atypia with enlarged vesicular nuclei and prominent nucleoli
#7617
middle Confidence
Subject:
cuboidal_cells
(Cell Type)
→
show
→
Object:
enlarged_vesicular_nuclei
(Nuclear characteristics)
Original: cuboidal cells#show#cytologic atypia with enlarged vesicular nuclei and prominent nucleoli
#7616
middle Confidence
Subject:
cuboidal_cells
(Cell Type)
→
show
→
Object:
cytologic_atypia
(Cytological atypia)
Original: cuboidal cells#show#cytologic atypia with enlarged vesicular nuclei and prominent nucleoli
#7583
middle Confidence
Subject:
mucinous_adenocarcinoma
(Tumor type)
→
is_characterized_by
→
Object:
neoplastic_cells_floating
(Cell morphology)
Original: mucinous adenocarcinoma#is characterized by#large pools of mucoid material with neoplastic cells floating
#7582
middle Confidence
Subject:
mucinous_adenocarcinoma
(Tumor type)
→
is_characterized_by
→
Object:
large_pools_of_mucoid_material
(Histological characteristics)
Original: mucinous adenocarcinoma#is characterized by#large pools of mucoid material with neoplastic cells floating
#7479
middle Confidence
Subject:
partial_atrophy
(Pathological changes)
→
is_defined_as
→
Object:
benign_prostate_glands_with_scant_cytoplasm
(Benign tissue)
Original: partial atrophy#is defined as#benign prostate glands with scant cytoplasm
#7478
middle Confidence
Subject:
partial_atrophy
(Pathological changes)
→
is_diagnostic_pitfall_for
→
Object:
surgical_pathologists
(Clinical Pathologist)
Original: partial atrophy in prostate needle cores#is another#diagnostic pitfall for surgical pathologists
#7470
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
possess
→
Object:
large_nuclei_with_moderately_distinct_nucleoli
(Cell morphology)
Original: tumor cells#possessed#large nuclei with moderately distinct nucleoli
#7469
middle Confidence
Subject:
FNA
(Histological samples)
→
reveals
→
Object:
bland_cells_with_pale_cytoplasm_and_small_nucleoli
(Cell morphology)
Original: FNA#revealed#bland cells with pale cytoplasm and small nucleoli
#7457
middle Confidence
Subject:
cytomorphologic_findings
(Cytological findings)
→
correlated_with
→
Object:
adenoid_cystic_pattern
(Histological subtype)
Original: cytomorphologic findings#correlated with#adenoid cystic pattern in histology
#7456
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
characterized_by
→
Object:
scant_cytoplasm
(Cytoplasmic characteristics)
Original: bronchial brushing smears#revealed#large clusters of neoplastic cells with scant cytoplasm
#7453
middle Confidence
Subject:
histological_biopsy_sample
(Tissue specimens)
→
revealed
→
Object:
large_polygonal_cells
(Tumor cell morphology)
Original: Histological biopsy sample#revealed#tumor cells with solid growth pattern/ necrotic materials/ and large polygonal cells
#7452
middle Confidence
Subject:
histological_biopsy_sample
(Tissue specimens)
→
revealed
→
Object:
necrotic_materials
(Tissue necrosis components)
Original: Histological biopsy sample#revealed#tumor cells with solid growth pattern/ necrotic materials/ and large polygonal cells
#7451
middle Confidence
Subject:
histological_biopsy_sample
(Tissue specimens)
→
revealed
→
Object:
tumor_cells_with_solid_growth_pattern
(Tumor cell phenotype)
Original: Histological biopsy sample#revealed#tumor cells with solid growth pattern/ necrotic materials/ and large polygonal cells
#7435
middle Confidence
Subject:
Papanicolaou_smear
(Diagnostic techniques)
→
demonstrated
→
Object:
neoplastic_components
(Tumor cell components)
Original: The Papanicolaou smear#demonstrated#2 distinct neoplastic components
#7434
middle Confidence
Subject:
PLCIS
(Pathological diagnosis entity)
→
is_defined_as
→
Object:
dyscohesive_cells_with_acinar_expansion_and_nuclear_pleomorphism
(Cell morphology)
Original: PLCIS#is defined as#dyscohesive cells with acinar expansion and nuclear pleomorphism
#7433
middle Confidence
Subject:
squash_cytology
(Cytological detection technology)
→
showed
→
Object:
uniform_tumor_cells_in_clusters_or_sheets
(Tumor cell morphology)
Original: Squash cytology#showed#uniform tumor cells in clusters or sheets
#7432
middle Confidence
Subject:
FNA_cytology
(Cytological detection technology)
→
is_presented_with
→
Object:
endoscopic_features
(Endoscopic features)
Original: The FNA cytologic findings#are presented#along with histologic/ immunohistochemical and endoscopic features
#7431
middle Confidence
Subject:
FNA_cytology
(Cytological detection technology)
→
is_presented_with
→
Object:
immunohistochemical_features
(Immunohistochemical characteristics)
Original: The FNA cytologic findings#are presented#along with histologic/ immunohistochemical and endoscopic features
#7430
middle Confidence
Subject:
FNA_cytology
(Cytological detection technology)
→
is_presented_with
→
Object:
histologic_features
(Histological characteristics)
Original: The FNA cytologic findings#are presented#along with histologic/ immunohistochemical and endoscopic features
#7429
middle Confidence
Subject:
fine_needle_aspiration_cytology
(Diagnostic techniques)
→
was_suspicious_for
→
Object:
malignancy
(Disease phenotype)
Original: Fine needle aspiration cytology#was#undiagnostic but suspicious for malignancy
#7428
middle Confidence
Subject:
fine_needle_aspiration_cytology
(Diagnostic techniques)
→
was
→
Object:
undiagnostic_result
(Diagnosis conclusion)
Original: Fine needle aspiration cytology#was#undiagnostic but suspicious for malignancy
#7398
middle Confidence
Subject:
CS
(Cytological methods)
→
compared_to
→
Object:
perinucleolar_halo
(Nuclear morphology)
Original: Compared to C-S#the incidences of trabecular and hobnail patterns/ collagenous stroma/ naked capillaries/ intercellular spaces/ convoluted nuclei/ eosinophilic nucleoli/ and perinucleolar halo#were increased
#7397
middle Confidence
Subject:
CS
(Cytological methods)
→
compared_to
→
Object:
eosinophilic_nucleoli
(Nuclear morphology)
Original: Compared to C-S#the incidences of trabecular and hobnail patterns/ collagenous stroma/ naked capillaries/ intercellular spaces/ convoluted nuclei/ eosinophilic nucleoli/ and perinucleolar halo#were increased
#7396
middle Confidence
Subject:
CS
(Cytological methods)
→
compared_to
→
Object:
convoluted_nuclei
(Nuclear morphology)
Original: Compared to C-S#the incidences of trabecular and hobnail patterns/ collagenous stroma/ naked capillaries/ intercellular spaces/ convoluted nuclei/ eosinophilic nucleoli/ and perinucleolar halo#were increased
#7395
middle Confidence
Subject:
CS
(Cytological methods)
→
compared_to
→
Object:
intercellular_spaces
(Histological characteristics)
Original: Compared to C-S#the incidences of trabecular and hobnail patterns/ collagenous stroma/ naked capillaries/ intercellular spaces/ convoluted nuclei/ eosinophilic nucleoli/ and perinucleolar halo#were increased
#7394
middle Confidence
Subject:
CS
(Cytological methods)
→
compared_to
→
Object:
naked_capillaries
(Histological characteristics)
Original: Compared to C-S#the incidences of trabecular and hobnail patterns/ collagenous stroma/ naked capillaries/ intercellular spaces/ convoluted nuclei/ eosinophilic nucleoli/ and perinucleolar halo#were increased
#7393
middle Confidence
Subject:
CS
(Cytological methods)
→
compared_to
→
Object:
collagenous_stroma
(Histological characteristics)
Original: Compared to C-S#the incidences of trabecular and hobnail patterns/ collagenous stroma/ naked capillaries/ intercellular spaces/ convoluted nuclei/ eosinophilic nucleoli/ and perinucleolar halo#were increased
#7392
middle Confidence
Subject:
CS
(Cytological methods)
→
compared_to
→
Object:
hobnail_pattern
(Histological characteristics)
Original: Compared to C-S#the incidences of trabecular and hobnail patterns/ collagenous stroma/ naked capillaries/ intercellular spaces/ convoluted nuclei/ eosinophilic nucleoli/ and perinucleolar halo#were increased
#7391
middle Confidence
Subject:
CS
(Cytological methods)
→
compared_to
→
Object:
trabecular_pattern
(Histological characteristics)
Original: Compared to C-S#the incidences of trabecular and hobnail patterns/ collagenous stroma/ naked capillaries/ intercellular spaces/ convoluted nuclei/ eosinophilic nucleoli/ and perinucleolar halo#were increased
#7389
middle Confidence
Subject:
endometrial_cells
(Glandular epithelial cells)
→
display
→
Object:
nucleoli
(Cell morphology)
Original: nuclear hyperchromasia/ pleomorphism/ and nucleoli in normal endometrial cells#are#more obvious in cervical LBC preparations than in conventional smears
#7388
middle Confidence
Subject:
endometrial_cells
(Glandular epithelial cells)
→
display
→
Object:
Pleomorphism
(Cell morphology)
Original: nuclear hyperchromasia/ pleomorphism/ and nucleoli in normal endometrial cells#are#more obvious in cervical LBC preparations than in conventional smears
#7387
middle Confidence
Subject:
endometrial_cells
(Glandular epithelial cells)
→
display
→
Object:
nuclear_hyperchromasia
(Cell morphology)
Original: nuclear hyperchromasia/ pleomorphism/ and nucleoli in normal endometrial cells#are#more obvious in cervical LBC preparations than in conventional smears
#7386
middle Confidence
Subject:
high-grade_carcinoma_cells
(Tumor cells)
→
show
→
Object:
prominent_eosinophilic_nucleoli
(Cell morphology)
Original: high-grade carcinoma cells#showed#increased nuclear-cytoplasmic ratio/ prominent eosinophilic nucleoli/ and active mitosis
#7385
middle Confidence
Subject:
high-grade_carcinoma_cells
(Tumor cells)
→
show
→
Object:
increased_nuclear_cytoplasmic_ratio
(Cell morphology)
Original: high-grade carcinoma cells#showed#increased nuclear-cytoplasmic ratio/ prominent eosinophilic nucleoli/ and active mitosis
#7363
middle Confidence
Subject:
smears
(Test samples)
→
displayed
→
Object:
prominent_nucleoli
(Cytological characteristics)
Original: smears#displayed#large cells with granular cytoplasm and prominent nucleoli
#7362
middle Confidence
Subject:
smears
(Test samples)
→
displayed
→
Object:
large_cells_with_granular_cytoplasm
(Cytological characteristics)
Original: smears#displayed#large cells with granular cytoplasm and prominent nucleoli
#7361
middle Confidence
Subject:
bronchial_brushing_cytology_specimens
(Test samples)
→
contained
→
Object:
malignant_cells_with_hyperchromatic_nuclei
(Cytological characteristics)
Original: bronchial brushing cytology specimens#contained#malignant cells with hyperchromatic nuclei
#7360
middle Confidence
Subject:
fine_needle_aspiration_biopsy
(Diagnostic techniques)
→
revealed
→
Object:
plasma_cells
(Immune cells)
Original: fine-needle aspiration biopsy#revealed#clusters of plasma cells
#7251
middle Confidence
Subject:
GIST
(Tumor)
→
correlation_with
→
Object:
immunocytochemical_staining
(Immunocytochemistry)
Original: Case of GIST#was reported for#correlation of imaging and cytologic features with immunocytochemical staining
#7250
middle Confidence
Subject:
GIST
(Tumor)
→
correlation_with
→
Object:
cytologic_features
(Cytological characteristics)
Original: Case of GIST#was reported for#correlation of imaging and cytologic features with immunocytochemical staining
#7249
middle Confidence
Subject:
GIST
(Tumor)
→
correlation_with
→
Object:
imaging_features
(Imaging features)
Original: Case of GIST#was reported for#correlation of imaging and cytologic features with immunocytochemical staining
#7228
middle Confidence
Subject:
cell_nuclei
(Nucleus)
→
appear
→
Object:
enlarged_or_pleomorphic_or_bizarre
(Nuclear characteristics)
Original: Rare cell nuclei#appear#enlarged/ pleomorphic/ or bizarre
#7227
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
have
→
Object:
conspicuous_nucleoli
(Nuclear characteristics)
Original: Tumor cells#have#conspicuous nucleoli
#7226
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_present_in
→
Object:
syncytial_groups_with_pleomorphic_nuclei
(Organizational structure characteristics)
Original: Tumor cells#were present in#syncytial groups with pleomorphic nuclei
#7225
middle Confidence
Subject:
rhabdoid_morphologic_features
(Tumor morphological characteristics)
→
were_not_identified
→
Object:
classic_type
(Tumor subtype)
Original: Classic rhabdoid morphologic features#were not#identified
#7201
middle Confidence
Subject:
pelvic_endometriosis
(disease)
→
diagnosed_by
→
Object:
touch_imprint_cytology
(Diagnostic techniques)
Original: Pelvic endometriosis#was diagnosed#on touch imprint cytology
#7199
middle Confidence
Subject:
metastatic_cells
(Tumor cells)
→
diagnosed_as
→
Object:
pheochromocytoma
(Tumor type)
Original: A diagnosis of pheochromocytoma with multiple metastases#was made#based on gross and histologic findings
#7198
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
diagnosed_as
→
Object:
neuroendocrine_neoplasia
(Tumor type)
Original: The cytopathologic interpretation#was#neuroendocrine neoplasia/ either metastatic or multicentric
#7197
middle Confidence
Subject:
anaplastic_carcinoma
(Tumor type)
→
reviewed_by
→
Object:
cytologic_evaluation_by_FNA
(Diagnostic techniques)
Original: Four pure insular carcinomas (IC) and one IC with focal anaplastic carcinoma (AC)#were reviewed#using cytologic evaluation by fine-needle aspiration (FNA)
#7196
middle Confidence
Subject:
insular_carcinoma
(Tumor type)
→
reviewed_by
→
Object:
cytologic_evaluation_by_FNA
(Diagnostic techniques)
Original: Four pure insular carcinomas (IC) and one IC with focal anaplastic carcinoma (AC)#were reviewed#using cytologic evaluation by fine-needle aspiration (FNA)
#7193
middle Confidence
Subject:
plasmacytoid_cells
(Cell Type)
→
are_characterized_by
→
Object:
inconspicuous_nucleoli
(Nucleolus not obvious)
Original: Fine-needle aspiration#revealed#epithelioid and plasmacytoid cells with elongated nuclei and fine chromatin
#7192
middle Confidence
Subject:
epithelioid_cells
(Cell Type)
→
are_characterized_by
→
Object:
fine_chromatin
(Chromatin characteristics)
Original: Fine-needle aspiration#revealed#epithelioid and plasmacytoid cells with elongated nuclei and fine chromatin
#7191
middle Confidence
Subject:
epithelioid_cells
(Cell Type)
→
are_characterized_by
→
Object:
elongated_nuclei
(Nuclear characteristics)
Original: Fine-needle aspiration#revealed#epithelioid and plasmacytoid cells with elongated nuclei and fine chromatin
#7190
middle Confidence
Subject:
Retropharyngeal_lymph_node_neoplasm
(Tumor type)
→
is_characterized_by
→
Object:
Necrosis
(Necrosis)
Original: FNA cytology#revealed#plasmacytoid cells with nucleoli/ intranuclear inclusions/ and mitotic figures
#7189
middle Confidence
Subject:
plasmacytoid_cells
(Cell Type)
→
are_characterized_by
→
Object:
mitotic_figures
(Mitotic figures)
Original: FNA cytology#revealed#plasmacytoid cells with nucleoli/ intranuclear inclusions/ and mitotic figures
#7188
middle Confidence
Subject:
plasmacytoid_cells
(Cell Type)
→
are_characterized_by
→
Object:
intranuclear_inclusions
(Intranuclear inclusion bodies)
Original: FNA cytology#revealed#plasmacytoid cells with nucleoli/ intranuclear inclusions/ and mitotic figures
#7187
middle Confidence
Subject:
plasmacytoid_cells
(Cell Type)
→
are_characterized_by
→
Object:
nucleoli
(Nucleolus)
Original: FNA cytology#revealed#plasmacytoid cells with nucleoli/ intranuclear inclusions/ and mitotic figures
#7186
middle Confidence
Subject:
Atypical large lymphoid cells
(Tumor cells)
→
are_characterized_by
→
Object:
obvious_mitotic_figures
(Mitotic figures)
Original: Atypical large lymphoid cells#are located in#small blood vessels and capillary lumen with little cytoplasm/ hyperchromasia/ prominent nucleoli/ and obvious mitotic figures
#7185
middle Confidence
Subject:
Atypical large lymphoid cells
(Tumor cells)
→
are_characterized_by
→
Object:
prominent_nucleoli
(Nucleolus is obvious)
Original: Atypical large lymphoid cells#are located in#small blood vessels and capillary lumen with little cytoplasm/ hyperchromasia/ prominent nucleoli/ and obvious mitotic figures
#7184
middle Confidence
Subject:
Atypical large lymphoid cells
(Tumor cells)
→
are_characterized_by
→
Object:
hyperchromasia
(Dark chromatin)
Original: Atypical large lymphoid cells#are located in#small blood vessels and capillary lumen with little cytoplasm/ hyperchromasia/ prominent nucleoli/ and obvious mitotic figures
#7183
middle Confidence
Subject:
Atypical large lymphoid cells
(Tumor cells)
→
are_characterized_by
→
Object:
little_cytoplasm
(Cytoplasmic characteristics)
Original: Atypical large lymphoid cells#are located in#small blood vessels and capillary lumen with little cytoplasm/ hyperchromasia/ prominent nucleoli/ and obvious mitotic figures
#7182
middle Confidence
Subject:
Atypical large lymphoid cells
(Tumor cells)
→
are_located_in
→
Object:
small_blood_vessels
(Vascular structure)
Original: Atypical large lymphoid cells#are located in#small blood vessels and capillary lumen with little cytoplasm/ hyperchromasia/ prominent nucleoli/ and obvious mitotic figures
#7181
middle Confidence
Subject:
Malignancy
(Disease phenotype)
→
is_evidenced_by
→
Object:
prominent_nucleoli
(Nucleolus is obvious)
Original: Malignancy#is evidenced by#increased mitotic rate/ necrosis/ nuclear atypia/ pleomorphism/ hyperchromasia/ and prominent nucleoli
#7180
middle Confidence
Subject:
Malignancy
(Disease phenotype)
→
is_evidenced_by
→
Object:
hyperchromasia
(Dark chromatin)
Original: Malignancy#is evidenced by#increased mitotic rate/ necrosis/ nuclear atypia/ pleomorphism/ hyperchromasia/ and prominent nucleoli
#7179
middle Confidence
Subject:
Malignancy
(Disease phenotype)
→
is_evidenced_by
→
Object:
Pleomorphism
(Cell polymorphism)
Original: Malignancy#is evidenced by#increased mitotic rate/ necrosis/ nuclear atypia/ pleomorphism/ hyperchromasia/ and prominent nucleoli
#7178
middle Confidence
Subject:
Malignancy
(Disease phenotype)
→
is_evidenced_by
→
Object:
nuclear_atypia
(Nuclear abnormalities)
Original: Malignancy#is evidenced by#increased mitotic rate/ necrosis/ nuclear atypia/ pleomorphism/ hyperchromasia/ and prominent nucleoli
#7177
middle Confidence
Subject:
Malignancy
(Disease phenotype)
→
is_evidenced_by
→
Object:
Necrosis
(Cell death characteristics)
Original: Malignancy#is evidenced by#increased mitotic rate/ necrosis/ nuclear atypia/ pleomorphism/ hyperchromasia/ and prominent nucleoli
#7176
middle Confidence
Subject:
Malignancy
(Disease phenotype)
→
is_evidenced_by
→
Object:
increased_mitotic_rate
(Cell proliferation characteristics)
Original: Malignancy#is evidenced by#increased mitotic rate/ necrosis/ nuclear atypia/ pleomorphism/ hyperchromasia/ and prominent nucleoli
#7175
middle Confidence
Subject:
Tumors
(Tumor tissue)
→
could_be_mistaken_for
→
Object:
melanoma
(Tumor type)
Original: Tumors#could be mistaken for#carcinoma/ sarcoma/ or melanoma due to cohesive growth and sharp interface with fibrous stroma
#7174
middle Confidence
Subject:
Tumors
(Tumor tissue)
→
could_be_mistaken_for
→
Object:
sarcoma
(Tumor type)
Original: Tumors#could be mistaken for#carcinoma/ sarcoma/ or melanoma due to cohesive growth and sharp interface with fibrous stroma
#7173
middle Confidence
Subject:
Tumors
(Tumor tissue)
→
could_be_mistaken_for
→
Object:
carcinoma
(Tumor type)
Original: Tumors#could be mistaken for#carcinoma/ sarcoma/ or melanoma due to cohesive growth and sharp interface with fibrous stroma
#7148
middle Confidence
Subject:
fine_needle_aspiration
(Diagnostic techniques)
→
shows
→
Object:
clusters_of_epithelial_cells_with_inconspicuous_nucleoli
(Cell structure)
Original: Fine needle aspiration#shows#clusters of epithelial cells with clear cytoplasm and inconspicuous nucleoli
#7147
middle Confidence
Subject:
fine_needle_aspiration
(Diagnostic techniques)
→
shows
→
Object:
clusters_of_epithelial_cells_with_clear_cytoplasm
(Cell structure)
Original: Fine needle aspiration#shows#clusters of epithelial cells with clear cytoplasm and inconspicuous nucleoli
#7146
middle Confidence
Subject:
small_glands_between_larger_benign_glands
(Organizational Structure)
→
are_seen_in
→
Object:
carcinoma
(Tumor type)
Original: Small glands between larger benign glands#are seen in#80% of carcinomas
#7112
middle Confidence
Subject:
Cells
(cell)
→
display
→
Object:
oval_shape
(Cell morphology)
Original: Cells#are#semiround or oval
#7111
middle Confidence
Subject:
Cells
(cell)
→
display
→
Object:
semiround_shape
(Cell morphology)
Original: Cells#are#semiround or oval
#7011
middle Confidence
Subject:
Patient
(patient)
→
is_examined_by
→
Object:
Immunohistochemical stain
(Detection Methods)
Original: Patients#are investigated through#hematoxylin and eosin-stained slides and immunohistochemical stains
#7010
middle Confidence
Subject:
Patient
(patient)
→
is_examined_by
→
Object:
hematoxylin and eosin-stained slide
(Detection Methods)
Original: Patients#are investigated through#hematoxylin and eosin-stained slides and immunohistochemical stains
#6979
middle Confidence
Subject:
cytologic_findings
(Cytological characteristics)
→
are_presented_for
→
Object:
Ewings_sarcoma
(Tumor)
Original: cytologic findings#are presented for#Ewing's sarcoma in fine needle aspiration biopsies
#6978
middle Confidence
Subject:
FNA_cytology
(Pathological technology)
→
was_performed_on
→
Object:
penile_nodules
(Lump)
Original: Fine-needle aspiration (FNA) cytology#was performed on#penile nodules
#6977
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
form
→
Object:
sheets_between_collagen_bundles
(Organizational structure characteristics)
Original: neoplastic cells#form#clusters and sheets between collagen bundles
#6976
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
form
→
Object:
clusters_between_collagen_bundles
(Organizational structure characteristics)
Original: neoplastic cells#form#clusters and sheets between collagen bundles
#6975
middle Confidence
Subject:
tumor
(Tumor)
→
is_classified_as
→
Object:
poorly_granulated
(Tumor subtype)
Original: tumor#is classified as#poorly granulated with nuclear atypia and multinucleated cells
#6974
middle Confidence
Subject:
tumor
(Tumor)
→
is_characterized_by
→
Object:
malignant_cells_with_prominent_nucleoli
(Cell morphology)
Original: tumor#is characterized by#malignant cells with granular cytoplasm/ vesicular nuclei/ and prominent nucleoli
#6973
middle Confidence
Subject:
tumor
(Tumor)
→
is_characterized_by
→
Object:
malignant_cells_with_vesicular_nuclei
(Cell morphology)
Original: tumor#is characterized by#malignant cells with granular cytoplasm/ vesicular nuclei/ and prominent nucleoli
#6972
middle Confidence
Subject:
tumor
(Tumor)
→
is_characterized_by
→
Object:
malignant_cells_with_granular_cytoplasm
(Cell morphology)
Original: tumor#is characterized by#malignant cells with granular cytoplasm/ vesicular nuclei/ and prominent nucleoli
#6949
middle Confidence
Subject:
polygonal_neoplastic_cells
(Tumor cells)
→
contain
→
Object:
prominent_nucleoli
(Cell nucleolus characteristics)
Original: polygonal neoplastic cells#contain#prominent nucleoli
#6948
middle Confidence
Subject:
malignant_melanoma
(Malignant tumors)
→
is_composed_of
→
Object:
rhabdoid_cells
(Cell Type)
Original: malignant melanoma#is composed of#rhabdoid cells
#6947
middle Confidence
Subject:
chondrosarcoma
(Malignant tumors)
→
is_associated_with
→
Object:
prominent_nucleoli
(Cell nucleolus characteristics)
Original: chondrosarcoma#is associated with#prominent nucleoli
#6946
middle Confidence
Subject:
prostatic_carcinomas
(Malignant tumors)
→
present_with
→
Object:
multiple_histologic_patterns
(Histological phenotype)
Original: prostatic carcinomas#present with#multiple histologic patterns
#6945
middle Confidence
Subject:
nuclear_size
(Nuclear morphology)
→
correlates_with
→
Object:
clinical_groups
(Disease classification)
Original: nuclear size#correlates with#clinical groups
#6942
middle Confidence
Subject:
patients
(patient)
→
present_with
→
Object:
shortness_of_breath
(symptom)
Original: patients#present with#chest pain/ cough/ and shortness of breath
#6941
middle Confidence
Subject:
patients
(patient)
→
present_with
→
Object:
cough
(symptom)
Original: patients#present with#chest pain/ cough/ and shortness of breath
#6940
middle Confidence
Subject:
patients
(patient)
→
present_with
→
Object:
chest_pain
(symptom)
Original: patients#present with#chest pain/ cough/ and shortness of breath
#6939
middle Confidence
Subject:
FNA
(Cytology)
→
did_not_make
→
Object:
definitive_diagnosis
(Diagnosis conclusion)
Original: FNA#did not make#a definitive diagnosis
#6924
middle Confidence
Subject:
FNA_cytologic_smears
(Cytology smear)
→
showed
→
Object:
large_polygonal_tumor_cells
(Cell Type)
Original: FNA cytologic smears#showed#large polygonal tumor cells with granular or vacuolated eosinophilic cytoplasm and eccentric nuclei with one distinct nucleolus
#6898
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_positive_for
→
Object:
estrogen_receptor
(Nuclear receptors)
Original: Tumors#were positive for#vimentin/ epithelial membrane antigen/ and estrogen receptor
#6897
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_positive_for
→
Object:
epithelial_membrane_antigen
(Membrane antigen)
Original: Tumors#were positive for#vimentin/ epithelial membrane antigen/ and estrogen receptor
#6896
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
were_positive_for
→
Object:
vimentin
(Cytoskeletal proteins)
Original: Tumors#were positive for#vimentin/ epithelial membrane antigen/ and estrogen receptor
#6895
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
showed_positivity_with
→
Object:
CAM_5.2_antibody
(Antibody)
Original: Neoplastic cells#showed positivity with#CAM 5.2 antibodies
#6878
middle Confidence
Subject:
mixed_mullerian_tumor
(Tumor type)
→
must_be_differentiated_from
→
Object:
Müllerian_carcinofibroma
(Tumor type)
Original: Mixed Müllerian tumor#must be differentiated from#malignant mixed Müllerian tumor and Müllerian carcinofibroma
#6877
middle Confidence
Subject:
mixed_mullerian_tumor
(Tumor type)
→
must_be_differentiated_from
→
Object:
Müllerian_carcinosarcoma
(Tumor type)
Original: Mixed Müllerian tumor#must be differentiated from#malignant mixed Müllerian tumor and Müllerian carcinofibroma
#6876
middle Confidence
Subject:
mixed_mullerian_tumor
(Tumor type)
→
must_be_differentiated_from
→
Object:
malignant_mixed_Müllerian_tumor
(Tumor type)
Original: Mixed Müllerian tumor#must be differentiated from#malignant mixed Müllerian tumor and Müllerian carcinofibroma
#6839
middle Confidence
Subject:
gland_like_space
(Organizational Structure)
→
contained
→
Object:
mucin
(Molecular components)
Original: Gland-like spaces#contained#mucin occasionally
#6831
middle Confidence
Subject:
feline_ONB
(Tumor diseases)
→
is_reported_with
→
Object:
immunohistochemical_features
(Immunohistochemical characteristics)
Original: feline ONB#is reported with#cytological/ histological/ and immunohistochemical features
#6830
middle Confidence
Subject:
feline_ONB
(Tumor diseases)
→
is_reported_with
→
Object:
histological_features
(Histological characteristics)
Original: feline ONB#is reported with#cytological/ histological/ and immunohistochemical features
#6829
middle Confidence
Subject:
feline_ONB
(Tumor diseases)
→
is_reported_with
→
Object:
cytological_features
(Cytological characteristics)
Original: feline ONB#is reported with#cytological/ histological/ and immunohistochemical features
#6809
middle Confidence
Subject:
patients
(patient)
→
presented_with
→
Object:
shortness_of_breath
(Clinical symptoms)
Original: patients#presented with#chest pain and shortness of breath
#6808
middle Confidence
Subject:
patients
(patient)
→
presented_with
→
Object:
chest_pain
(Clinical symptoms)
Original: patients#presented with#chest pain and shortness of breath
#6807
middle Confidence
Subject:
adenomas
(Tumor type)
→
are
→
Object:
tubulovillous
(Histological type)
Original: adenomas#are#tubular/ villous/ or tubulovillous
#6806
middle Confidence
Subject:
adenomas
(Tumor type)
→
are
→
Object:
villous
(Histological type)
Original: adenomas#are#tubular/ villous/ or tubulovillous
#6805
middle Confidence
Subject:
adenomas
(Tumor type)
→
are
→
Object:
tubular
(Histological type)
Original: adenomas#are#tubular/ villous/ or tubulovillous
#6804
middle Confidence
Subject:
pleural_fluid_cytology
(Cytology)
→
revealed
→
Object:
nuclear_pleomorphism
(Cell morphology)
Original: pleural fluid cytology#revealed#abundant papillary clusters with nuclear pleomorphism
#6803
middle Confidence
Subject:
pleural_fluid_cytology
(Cytology)
→
revealed
→
Object:
abundant_papillary_clusters
(Cell morphology)
Original: pleural fluid cytology#revealed#abundant papillary clusters with nuclear pleomorphism
#6802
middle Confidence
Subject:
neurosecretory_granules
(Subcellular structure)
→
are_recognized_in
→
Object:
tumors_via_electron_microscopy
(Tumor structure)
Original: neurosecretory granules#are recognized in#tumors via electron microscopy
#6794
middle Confidence
Subject:
Biopsy_examination
(Histological examination)
→
shows
→
Object:
nests_of_tumor_mass_in_lamina_and_muscularis_mucosae
(Tumor tissue structure)
Original: Biopsy examination#showed#nests of tumor mass in lamina and muscularis mucosae
#6793
middle Confidence
Subject:
MPNT_cases
(Tumor Cases)
→
differ_from
→
Object:
typical_Ewing's_sarcoma
(Tumor phenotype)
Original: MPNT cases#differed from#typical Ewing's sarcoma in cytological features
#6686
middle Confidence
Subject:
cellular_smears
(Cytosmear)
→
showed
→
Object:
cells_with_abundant_poorly_defined_fragile_cytoplasm_bare_nuclei_anisonucleosis_salt_and_pepper_chromatin_variable_nucleoli_and_few_ganglion_cell_like_cells
(Cell morphology)
Original: Cellular smears#showed#cells with abundant/ poorly defined fragile cytoplasm/ bare nuclei/ anisonucleosis/ "salt and pepper" chromatin/ variable nucleoli/ and few ganglion cell-like cells
#6685
middle Confidence
Subject:
malignant_cells
(Tumor cells)
→
exhibited
→
Object:
paranuclear_dense_inclusions
(Pericytotic inclusion bodies)
Original: malignant cells#exhibited#vesicular nuclei/ prominent nucleoli/ and paranuclear dense inclusions
#6684
middle Confidence
Subject:
malignant_cells
(Tumor cells)
→
exhibited
→
Object:
prominent_nucleoli
(Nucleolar morphology)
Original: malignant cells#exhibited#vesicular nuclei/ prominent nucleoli/ and paranuclear dense inclusions
#6683
middle Confidence
Subject:
malignant_cells
(Tumor cells)
→
exhibited
→
Object:
vesicular_nuclei
(Nuclear morphology)
Original: malignant cells#exhibited#vesicular nuclei/ prominent nucleoli/ and paranuclear dense inclusions
#6460
middle Confidence
Subject:
TP53
(Transcription Factors)
→
shows_upregulated_AgNOR_quantities_in
→
Object:
leukemia_cells
(Tumor cells)
Original: AgNOR quantities#differ significantly between#healthy donors and p53-positive leukemia cells
#6322
middle Confidence
Subject:
adrenal_glands
(organ)
→
exhibit
→
Object:
ultrastructural_pathology_in_Cushing's_syndrome
(Disease phenotype)
Original: adrenal glands#exhibit#ultrastructural pathology in Cushing's syndrome
#6287
middle Confidence
Subject:
calpain_3_splicing_variant
(Protein variants)
→
is_identified_in
→
Object:
melanoma_cell_lines
(Cancer cell lines)
Original: Novel splicing variants of calpain 3#are identified in#melanoma cell lines
#6286
middle Confidence
Subject:
predictive_value
(Diagnostic value)
→
is_investigated_in
→
Object:
leukemic_lymphocytes
(Cell Type)
Original: Nucleolar morphology#is investigated for#predictive value in leukemic lymphocytes
#6285
middle Confidence
Subject:
Nucleolar_morphology
(Cellular substructure)
→
is_investigated_for
→
Object:
predictive_value
(Diagnostic value)
Original: Nucleolar morphology#is investigated for#predictive value in leukemic lymphocytes
#6231
middle Confidence
Subject:
lacunarity
(Fractal characteristics)
→
shows
→
Object:
difference_between_benign_and_malignant_cases
(Tumor phenotype differences)
Original: lacunarity#shows#a significant difference between benign and malignant cases
#6173
middle Confidence
Subject:
variation_in_nuclear_size
(Nuclear morphology)
→
distinguishes
→
Object:
AAH_pattern
(Lesion type)
Original: variation in nuclear size#distinguishes#three patterns in carcinoma and AAH
#6172
middle Confidence
Subject:
variation_in_nuclear_size
(Nuclear morphology)
→
distinguishes
→
Object:
carcinoma_pattern
(Tumor type)
Original: variation in nuclear size#distinguishes#three patterns in carcinoma and AAH
#6171
middle Confidence
Subject:
observer
(Observer)
→
evaluates
→
Object:
diagnostic_criteria_for_AAH
(Diagnostic criteria)
Original: Seven observers#evaluate#diagnostic criteria for separating AAH from carcinoma
#6164
middle Confidence
Subject:
small_cell_carcinoma
(Tumor pathology type)
→
misdiagnosed_as
→
Object:
nonprostatic_origin
(Disease phenotype)
Original: carcinoid-like lesions and small cell carcinomas#were misdiagnosed as#nonprostatic origin based on immunoreactivity
#6163
middle Confidence
Subject:
carcinoid-like_lesion
(Tumor pathology type)
→
misdiagnosed_as
→
Object:
nonprostatic_origin
(Disease phenotype)
Original: carcinoid-like lesions and small cell carcinomas#were misdiagnosed as#nonprostatic origin based on immunoreactivity
#6160
middle Confidence
Subject:
polymorphous_low-grade_adenocarcinoma
(Malignant tumors)
→
analyzed_by
→
Object:
AgNOR_technique
(Molecular detection technology)
Original: adenoid cystic carcinomas and polymorphous low-grade adenocarcinomas#were examined by#the silver-staining nucleolar organizer regions (AgNOR) technique
#6159
middle Confidence
Subject:
adenoid_cystic_carcinoma
(Malignant tumors)
→
analyzed_by
→
Object:
AgNOR_technique
(Molecular detection technology)
Original: adenoid cystic carcinomas and polymorphous low-grade adenocarcinomas#were examined by#the silver-staining nucleolar organizer regions (AgNOR) technique
#6151
middle Confidence
Subject:
non-Hodgkin's_lymphoma
(Malignant tumors)
→
analyzed_by
→
Object:
AgNOR_method
(Molecular detection technology)
Original: non-Hodgkin's lymphomas#have been studied by#the argyrophil (AgNOR) method for nuclear organizer regions
#6123
middle Confidence
Subject:
Nucleolar_Organizer_Regions
(Chromatin domain)
→
are_studied_as
→
Object:
predictability_factors
(Predictors)
Original: Nucleolar Organizer Regions (NORs)#are studied as#predictability factors
#6058
middle Confidence
Subject:
5'ETS/45S_CISH
(45S_rRNA_CISH detection)
→
was_performed_on
→
Object:
high-grade_PIN
(High-grade prostatic intraepithelial neoplasia)
Original: 5'ETS/45S CISH#was performed on#prostate carcinomas/ high-grade PIN/ and benign prostatic tissues
#6057
middle Confidence
Subject:
5'ETS/45S_CISH
(45S_rRNA_CISH detection)
→
was_performed_on
→
Object:
prostate_carcinoma
(Prostate cancer)
Original: 5'ETS/45S CISH#was performed on#prostate carcinomas/ high-grade PIN/ and benign prostatic tissues
#6056
middle Confidence
Subject:
western_pathologists
(Pathology Specialist)
→
diagnose
→
Object:
high-grade_dysplasia
(High-grade intraepithelial neoplasia)
Original: Western pathologists#diagnose#carcinoma in situ and high-grade dysplasia differently in colorectal adenomas
#6055
middle Confidence
Subject:
western_pathologists
(Pathology Specialist)
→
diagnose
→
Object:
carcinoma_in_situ
(Carcinoma in situ)
Original: Western pathologists#diagnose#carcinoma in situ and high-grade dysplasia differently in colorectal adenomas
#6054
middle Confidence
Subject:
AgNOR_staining
(Silver staining of the nucleolar organizer region)
→
indicates
→
Object:
malignant_potential
(Malignant Potential)
Original: AgNOR staining#indicates#cell proliferation and malignant potential of lesions
#6053
middle Confidence
Subject:
AgNOR_staining
(Silver staining of the nucleolar organizer region)
→
indicates
→
Object:
cell_proliferation
(Cell proliferation)
Original: AgNOR staining#indicates#cell proliferation and malignant potential of lesions
#6047
middle Confidence
Subject:
DNA_Feulgen_staining
(DNA staining techniques)
→
is_used_in
→
Object:
diagnosis_of_recurrent_meningiomas
(Tumor diagnostic markers)
Original: Ki67 labelling index/ AgNOR/ and DNA Feulgen staining#were used in#studying recurrent and atypical meningiomas
#6046
middle Confidence
Subject:
AgNOR
(Nucleolar organizer region-associated silver staining)
→
is_used_in
→
Object:
diagnosis_of_recurrent_meningiomas
(Tumor diagnostic markers)
Original: Ki67 labelling index/ AgNOR/ and DNA Feulgen staining#were used in#studying recurrent and atypical meningiomas
#6015
middle Confidence
Subject:
PCNA
(Proliferating cell nuclear antigen)
→
assessed_in
→
Object:
medullary_thyroid_carcinoma
(disease)
Original: AgNORs and PCNA#assessed in#nodular C cell hyperplasia and early MTC
#6014
middle Confidence
Subject:
AgNOR
(Nucleolar organizer region-associated)
→
assessed_in
→
Object:
medullary_thyroid_carcinoma
(disease)
Original: AgNORs and PCNA#assessed in#nodular C cell hyperplasia and early MTC
#6012
middle Confidence
Subject:
AgNOR_volume
(Nucleolar organizer region-associated)
→
increased_in
→
Object:
borderline_adenoma
(Tissue lesions)
Original: AgNOR volumes#increased in#border-line adenoma compared to benign adenoma
#6011
middle Confidence
Subject:
DNA_instability
(Genomic instability)
→
increased_in
→
Object:
borderline_adenoma
(Tissue lesions)
Original: DNA-instability#increased in#border-line adenoma to invasive overt cancer
#6010
middle Confidence
Subject:
AgNOR
(Nucleolar organizer region-associated)
→
estimated_as
→
Object:
malignancy_marker
(Diagnostic markers)
Original: PCNA index and AgNORs#estimated as#markers of malignancy
#6009
middle Confidence
Subject:
PCNA_index
(Proliferating cell nuclear antigen)
→
estimated_as
→
Object:
malignancy_marker
(Diagnostic markers)
Original: PCNA index and AgNORs#estimated as#markers of malignancy
#6008
middle Confidence
Subject:
AgNOR_staining
(Dyeing technology)
→
applied_to
→
Object:
bladder_cancer
(disease)
Original: AgNOR staining#applied to#cell imprint preparations in bladder cancer
#6007
middle Confidence
Subject:
AgNOR_staining
(Dyeing technology)
→
applied_to
→
Object:
cell_imprint_preparations
(Cytology samples)
Original: AgNOR staining#applied to#cell imprint preparations in bladder cancer
#6006
middle Confidence
Subject:
AgNOR_size
(Nucleolar organizer region-associated)
→
decreases_with
→
Object:
carcinoma_grade
(Disease classification)
Original: AgNOR size#became smaller with#increasing grade of carcinoma
#5995
middle Confidence
Subject:
AgNORs
(Nuclear structure markers)
→
differentiations
→
Object:
malignant_bladder_lesions
(Disease phenotype)
Original: AgNORs#differentiate between#benign/ borderline/ and malignant bladder lesions
#5994
middle Confidence
Subject:
AgNORs
(Nuclear structure markers)
→
differentiations
→
Object:
borderline_bladder_lesions
(Disease phenotype)
Original: AgNORs#differentiate between#benign/ borderline/ and malignant bladder lesions
#5993
middle Confidence
Subject:
AgNORs
(Nuclear structure markers)
→
differentiations
→
Object:
benign_bladder_lesions
(Disease phenotype)
Original: AgNORs#differentiate between#benign/ borderline/ and malignant bladder lesions
#5992
middle Confidence
Subject:
AgNOR_count
(Number of molecular modifications)
→
was_studied_in
→
Object:
inflammatory_pseudotumor
(Benign lesions)
Original: Expression of PCNA and AgNORs count#was studied in#primary lung cancer and inflammatory pseudotumor
#5991
middle Confidence
Subject:
AgNOR_count
(Number of molecular modifications)
→
was_studied_in
→
Object:
lung_cancer
(Tumor type)
Original: Expression of PCNA and AgNORs count#was studied in#primary lung cancer and inflammatory pseudotumor
#5990
middle Confidence
Subject:
PCNA_expression
(Protein expression)
→
was_studied_in
→
Object:
inflammatory_pseudotumor
(Benign lesions)
Original: Expression of PCNA and AgNORs count#was studied in#primary lung cancer and inflammatory pseudotumor
#5989
middle Confidence
Subject:
PCNA_expression
(Protein expression)
→
was_studied_in
→
Object:
lung_cancer
(Tumor type)
Original: Expression of PCNA and AgNORs count#was studied in#primary lung cancer and inflammatory pseudotumor
#5988
middle Confidence
Subject:
AgNOR_counting_per_nucleus
(Molecular detection methods)
→
is_more_valid_than
→
Object:
average_nuclear_volume_measurement
(Morphometric methods)
Original: Counting Ag-NORs per nucleus#is more valid/ accurate/ and economical than#measuring average nuclear volume
#5970
middle Confidence
Subject:
monoclonal_antibodies_to_IL2R
(Monoclonal antibodies)
→
stains
→
Object:
IL2R
(Cytokine receptors)
Original: Human solid tumors#are stained with#monoclonal antibodies to IL-2 and its receptor subunits
#5969
middle Confidence
Subject:
monoclonal_antibodies_to_IL2
(Monoclonal antibodies)
→
stains
→
Object:
IL2
(Cytokines)
Original: Human solid tumors#are stained with#monoclonal antibodies to IL-2 and its receptor subunits
#5955
middle Confidence
Subject:
AgNOR_activity
(Molecular activity)
→
is_lower_in
→
Object:
chronic_nasopharyngitis
(Inflammation)
Original: AgNOR activity#is higher in#carcinomas compared to benign tumors/ chronic nasopharyngitis/ and normal nasopharyngeal tissues
#5930
middle Confidence
Subject:
malignant_follicular_tumors
(Malignant follicular tumor)
→
are_compared_for
→
Object:
cytologic_diagnosis
(Cytological diagnosis)
Original: benign and malignant follicular tumors#are compared for#cytologic diagnosis
#5929
middle Confidence
Subject:
benign_follicular_tumors
(Benign follicular tumor)
→
are_compared_for
→
Object:
cytologic_diagnosis
(Cytological diagnosis)
Original: benign and malignant follicular tumors#are compared for#cytologic diagnosis
#5927
middle Confidence
Subject:
AgNORs
(Silver-stained nucleolar organizer region)
→
are_observed_in
→
Object:
adenomatoid_odontogenic_tumors
(Tumor tissue)
Original: AgNORs#are observed in#ameloblastomas and adenomatoid odontogenic tumors
#5926
middle Confidence
Subject:
AgNORs
(Silver-stained nucleolar organizer region)
→
are_observed_in
→
Object:
ameloblastoma
(Tumor tissue)
Original: AgNORs#are observed in#ameloblastomas and adenomatoid odontogenic tumors
#5921
middle Confidence
Subject:
AgNOR_staining_technique
(Molecular detection technology)
→
facilitates
→
Object:
pathologic_differential_diagnosis
(Diagnostic Methods)
Original: AgNOR staining technique#facilitates#pathologic differential diagnosis of breast tumors and NHL
#5874
middle Confidence
Subject:
Ag-NOR_proteins
(Silver staining related proteins)
→
are_used_to_distinguish
→
Object:
malignant_tumors
(Malignant tumors)
Original: Ag-NOR proteins#are used to distinguish#benign from malignant tumors
#5873
middle Confidence
Subject:
Ag-NOR_proteins
(Silver staining related proteins)
→
are_used_to_distinguish
→
Object:
benign_tumors
(Benign tumors)
Original: Ag-NOR proteins#are used to distinguish#benign from malignant tumors
#5872
middle Confidence
Subject:
nucleoli_of_cancer_cells
(Nucleolus)
→
are_positively_stained_by
→
Object:
p120_monoclonal_antibody
(Monoclonal antibodies)
Original: nucleoli of cancer cells#are positively stained by#p120 monoclonal antibody
#5863
middle Confidence
Subject:
normal_breast_specimen
(Normal tissue)
→
is_identified_as
→
Object:
negative_for_nucleolar_fluorescence
(Test results)
Original: Normal breast specimens#were identified as#negative for nucleolar fluorescence
#5862
middle Confidence
Subject:
nucleolar_immunofluorescence
(Immunofluorescence signal)
→
is_not_found_in
→
Object:
inflammatory_disease
(Inflammatory diseases)
Original: Nucleolar immunofluorescence#was not found in#most normal tissue/ benign adenomas/ hyperplastic tissues/ and inflammatory diseases
#5861
middle Confidence
Subject:
nucleolar_immunofluorescence
(Immunofluorescence signal)
→
is_not_found_in
→
Object:
hyperplastic_tissue
(Hyperplastic tissue)
Original: Nucleolar immunofluorescence#was not found in#most normal tissue/ benign adenomas/ hyperplastic tissues/ and inflammatory diseases
#5860
middle Confidence
Subject:
nucleolar_immunofluorescence
(Immunofluorescence signal)
→
is_not_found_in
→
Object:
benign_adenoma
(Benign tumors)
Original: Nucleolar immunofluorescence#was not found in#most normal tissue/ benign adenomas/ hyperplastic tissues/ and inflammatory diseases
#5859
middle Confidence
Subject:
nucleolar_immunofluorescence
(Immunofluorescence signal)
→
is_not_found_in
→
Object:
normal_tissue
(Normal tissue)
Original: Nucleolar immunofluorescence#was not found in#most normal tissue/ benign adenomas/ hyperplastic tissues/ and inflammatory diseases
#5843
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
CK20
(Cell markers)
Original: tumor cells#are negative for#pan-CK (KL1)/ CK7/ CK14/ CK16/ and CK20
#5842
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
CK16
(Cell markers)
Original: tumor cells#are negative for#pan-CK (KL1)/ CK7/ CK14/ CK16/ and CK20
#5841
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
CK14
(Cell markers)
Original: tumor cells#are negative for#pan-CK (KL1)/ CK7/ CK14/ CK16/ and CK20
#5840
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
CK7
(Cell markers)
Original: tumor cells#are negative for#pan-CK (KL1)/ CK7/ CK14/ CK16/ and CK20
#5839
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_negative_for
→
Object:
pan-CK(KL1)
(Cell markers)
Original: tumor cells#are negative for#pan-CK (KL1)/ CK7/ CK14/ CK16/ and CK20
#5785
middle Confidence
Subject:
Immunohistochemistry
(Histological detection method)
→
shows
→
Object:
epithelial_membrane_antigen
(Protein markers)
Original: immunohistochemistry#shows#vimentin/ wide spectrum keratin/ and epithelial membrane antigen as the most consistent antigenic phenotypes
#5784
middle Confidence
Subject:
Immunohistochemistry
(Histological detection method)
→
shows
→
Object:
wide_spectrum_keratin
(Protein markers)
Original: immunohistochemistry#shows#vimentin/ wide spectrum keratin/ and epithelial membrane antigen as the most consistent antigenic phenotypes
#5783
middle Confidence
Subject:
Immunohistochemistry
(Histological detection method)
→
shows
→
Object:
vimentin
(Protein markers)
Original: immunohistochemistry#shows#vimentin/ wide spectrum keratin/ and epithelial membrane antigen as the most consistent antigenic phenotypes
#5775
middle Confidence
Subject:
Atrophic_cancer
(Tumor tissue)
→
is_associated_with
→
Object:
luminal_eosinophilic_proteinaceous_secretions
(Secretions)
Original: Atrophic cancer#is associated with#luminal eosinophilic proteinaceous secretions
#5773
middle Confidence
Subject:
Prostatic_adenocarcinoma
(Tumor tissue)
→
is_defined_as
→
Object:
malignant_acini_resembling_atrophy
(Organizational form)
Original: Prostatic adenocarcinoma#was defined as#malignant acini resembling atrophy
#5761
middle Confidence
Subject:
cytological_criteria
(Diagnostic criteria)
→
reveal
→
Object:
overlap_between_benign_and_malignant_cases
(Disease phenotype)
Original: Cytological criteria#reveal#significant overlap between benign and malignant cases
#5757
middle Confidence
Subject:
cells
(cell)
→
stained_positive_for
→
Object:
keratin
(protein)
Original: Cells#stained positive for#keratin
#5750
middle Confidence
Subject:
Cytologic_features_of_BC
(Cytological characteristics)
→
includes
→
Object:
scant_cytoplasm
(Scarce cytoplasm)
Original: Cytologic features of BC and BSQCC#included#palisading/ crush artifact/ hyperchromasia/ focal nuclear molding/ nucleoli/ scant cytoplasm
#5749
middle Confidence
Subject:
Cytologic_features_of_BC
(Cytological characteristics)
→
includes
→
Object:
nucleoli
(Nucleolus)
Original: Cytologic features of BC and BSQCC#included#palisading/ crush artifact/ hyperchromasia/ focal nuclear molding/ nucleoli/ scant cytoplasm
#5748
middle Confidence
Subject:
Cytologic_features_of_BC
(Cytological characteristics)
→
includes
→
Object:
focal_nuclear_molding
(Focal nuclear plasticity)
Original: Cytologic features of BC and BSQCC#included#palisading/ crush artifact/ hyperchromasia/ focal nuclear molding/ nucleoli/ scant cytoplasm
#5747
middle Confidence
Subject:
Cytologic_features_of_BC
(Cytological characteristics)
→
includes
→
Object:
hyperchromasia
(Dark chromatin)
Original: Cytologic features of BC and BSQCC#included#palisading/ crush artifact/ hyperchromasia/ focal nuclear molding/ nucleoli/ scant cytoplasm
#5746
middle Confidence
Subject:
Cytologic_features_of_BC
(Cytological characteristics)
→
includes
→
Object:
crush_artifact
(Cell damage characteristics)
Original: Cytologic features of BC and BSQCC#included#palisading/ crush artifact/ hyperchromasia/ focal nuclear molding/ nucleoli/ scant cytoplasm
#5745
middle Confidence
Subject:
Cytologic_features_of_BC
(Cytological characteristics)
→
includes
→
Object:
Palisading
(Cell arrangement characteristics)
Original: Cytologic features of BC and BSQCC#included#palisading/ crush artifact/ hyperchromasia/ focal nuclear molding/ nucleoli/ scant cytoplasm
#5744
middle Confidence
Subject:
Ductal_component_in_ApEMCa
(Glandular duct components)
→
shows
→
Object:
androgen_receptor_immunoreactivity
(Androgen receptor immunoreactivity)
Original: Ductal component in ApEMCa#was distinguished from#OEMCa by apical snouts/ intracytoplasmic vacuoles/ nuclear pleomorphism/ prominent nucleoli/ and androgen receptor immunoreactivity
#5743
middle Confidence
Subject:
Ductal_component_in_ApEMCa
(Glandular duct components)
→
shows
→
Object:
prominent_nucleoli
(Nucleolus is obvious)
Original: Ductal component in ApEMCa#was distinguished from#OEMCa by apical snouts/ intracytoplasmic vacuoles/ nuclear pleomorphism/ prominent nucleoli/ and androgen receptor immunoreactivity
#5742
middle Confidence
Subject:
Ductal_component_in_ApEMCa
(Glandular duct components)
→
shows
→
Object:
nuclear_pleomorphism
(Nuclear atypia)
Original: Ductal component in ApEMCa#was distinguished from#OEMCa by apical snouts/ intracytoplasmic vacuoles/ nuclear pleomorphism/ prominent nucleoli/ and androgen receptor immunoreactivity
#5741
middle Confidence
Subject:
Ductal_component_in_ApEMCa
(Glandular duct components)
→
shows
→
Object:
intracytoplasmic_vacuoles
(Cell structure characteristics)
Original: Ductal component in ApEMCa#was distinguished from#OEMCa by apical snouts/ intracytoplasmic vacuoles/ nuclear pleomorphism/ prominent nucleoli/ and androgen receptor immunoreactivity
#5740
middle Confidence
Subject:
Ductal_component_in_ApEMCa
(Glandular duct components)
→
shows
→
Object:
apical_snouts
(Cell structure characteristics)
Original: Ductal component in ApEMCa#was distinguished from#OEMCa by apical snouts/ intracytoplasmic vacuoles/ nuclear pleomorphism/ prominent nucleoli/ and androgen receptor immunoreactivity
#5739
middle Confidence
Subject:
Ductal_component_in_ApEMCa
(Glandular duct components)
→
is_distinguished_from
→
Object:
OEMCa
(Ovarian endometrioid carcinoma)
Original: Ductal component in ApEMCa#was distinguished from#OEMCa by apical snouts/ intracytoplasmic vacuoles/ nuclear pleomorphism/ prominent nucleoli/ and androgen receptor immunoreactivity
#5738
middle Confidence
Subject:
Lesion
(Tumor lesions)
→
shows_negativity_for
→
Object:
CAM_5.2
(Cytokeratin markers)
Original: Lesion#showed negativity for#CAM 5.2
#5699
middle Confidence
Subject:
nucleolar_organizer_regions
(Nucleolar organizer region)
→
quantified_in
→
Object:
lymph_node_metastasis
(Tumor metastasis)
Original: Expression of nucleolar organizer regions (NORs)#was quantified in#tumors and lymph node metastasis
#5698
middle Confidence
Subject:
nucleolar_organizer_regions
(Nucleolar organizer region)
→
quantified_in
→
Object:
tumors
(Tumor tissue)
Original: Expression of nucleolar organizer regions (NORs)#was quantified in#tumors and lymph node metastasis
#5697
middle Confidence
Subject:
nucleolar_organizer_regions
(Nucleolar organizer region)
→
were_quantified_in
→
Object:
transitional_bladder_cancer
(Disease phenotype)
Original: Nucleolar organizer regions#were quantified in#transitional bladder cancer using silver staining
#5680
middle Confidence
Subject:
nucleoli
(Nuclear structure)
→
showed_apparent_difference_in
→
Object:
endometrial_carcinoma
(disease)
Original: There#was an apparent difference in#size and irregularity of nucleoli between atypical hyperplasia and endometrial carcinoma
#5679
middle Confidence
Subject:
nucleoli
(Nuclear structure)
→
showed_apparent_difference_in
→
Object:
atypical_hyperplasia
(Pathological conditions)
Original: There#was an apparent difference in#size and irregularity of nucleoli between atypical hyperplasia and endometrial carcinoma
#5667
middle Confidence
Subject:
external_examination
(Physical examination)
→
showed
→
Object:
tan_colored_nodule_with_ulcer
(Clinical symptoms)
Original: external examination#showed#a tan-colored nodule with an overlying crust-covered ulcer on the left lower eyelid
#5666
middle Confidence
Subject:
granulocytic_sarcoma
(Tumor type)
→
is_composed_of
→
Object:
immature_leukemic_cells
(Tumor cells)
Original: Granulocytic sarcoma#is composed of#immature leukemic cells
#5665
middle Confidence
Subject:
Rhabdoid_tumor
(Tumor type)
→
has_phenotypic_features
→
Object:
poorly_differentiated_malignancy
(Disease phenotype)
Original: Rhabdoid tumor#has phenotypic features#in 10 poorly differentiated malignancies of the gastrointestinal tract
#5605
middle Confidence
Subject:
plasmacytoid_cells
(Cell Type)
→
exhibit
→
Object:
nuclear_grooves
(Cell morphology)
Original: Plasmacytoid cells#exhibit#dense blue cytoplasm/ perinuclear vacuoles/ and nuclear grooves
#5604
middle Confidence
Subject:
plasmacytoid_cells
(Cell Type)
→
exhibit
→
Object:
perinuclear_vacuoles
(Cell morphology)
Original: Plasmacytoid cells#exhibit#dense blue cytoplasm/ perinuclear vacuoles/ and nuclear grooves
#5603
middle Confidence
Subject:
plasmacytoid_cells
(Cell Type)
→
exhibit
→
Object:
dense_blue_cytoplasm
(Cell morphology)
Original: Plasmacytoid cells#exhibit#dense blue cytoplasm/ perinuclear vacuoles/ and nuclear grooves
#5602
middle Confidence
Subject:
benign_tumor_cells
(Tumor cells)
→
showed
→
Object:
lack_of_mitoses
(Cell morphology)
Original: Benign tumors#showed#abundant naked nuclei/ cytoplasm/ and lack of mitoses
#5601
middle Confidence
Subject:
benign_tumor_cells
(Tumor cells)
→
showed
→
Object:
Cytoplasm
(Cell morphology)
Original: Benign tumors#showed#abundant naked nuclei/ cytoplasm/ and lack of mitoses
#5600
middle Confidence
Subject:
benign_tumor_cells
(Tumor cells)
→
showed
→
Object:
abundant_naked_nuclei
(Cell morphology)
Original: Benign tumors#showed#abundant naked nuclei/ cytoplasm/ and lack of mitoses
#5599
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
exhibit
→
Object:
abundant_cytoplasm
(Cell morphology)
Original: Tumor cells#exhibit#vesicular nuclei/ nucleoli/ and abundant cytoplasm
#5598
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
exhibit
→
Object:
nucleoli
(Cell morphology)
Original: Tumor cells#exhibit#vesicular nuclei/ nucleoli/ and abundant cytoplasm
#5597
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
exhibit
→
Object:
vesicular_nuclei
(Cell morphology)
Original: Tumor cells#exhibit#vesicular nuclei/ nucleoli/ and abundant cytoplasm
#5596
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_arranged_in
→
Object:
irregular_aggregates
(Cell morphology)
Original: Tumor cells#are arranged in#solid or irregular aggregates
#5595
middle Confidence
Subject:
Tumor_cells
(Tumor cells)
→
are_arranged_in
→
Object:
solid_aggregates
(Cell morphology)
Original: Tumor cells#are arranged in#solid or irregular aggregates
#5591
middle Confidence
Subject:
Neoplastic_cells
(Tumor cells)
→
are_characterized_by
→
Object:
clear_nucleolus
(Cell morphology)
Original: Neoplastic cells#are characterized as#pleomorphic cells with eosinophilic cytoplasm and clear nucleolus
#5590
middle Confidence
Subject:
Neoplastic_cells
(Tumor cells)
→
are_characterized_by
→
Object:
eosinophilic_cytoplasm
(Cell morphology)
Original: Neoplastic cells#are characterized as#pleomorphic cells with eosinophilic cytoplasm and clear nucleolus
#5589
middle Confidence
Subject:
Neoplastic_cells
(Tumor cells)
→
are_characterized_as
→
Object:
pleomorphic_cells
(Cell morphology)
Original: Neoplastic cells#are characterized as#pleomorphic cells with eosinophilic cytoplasm and clear nucleolus
#5587
middle Confidence
Subject:
diagnosis_of_metastatic_Leydig_cell_tumor
(diagnosis)
→
can_be_made_by
→
Object:
Immunohistochemistry
(Molecular analysis)
Original: Diagnosis of metastatic Leydig cell tumor#can be made by#reviewing history/ cytomorphologic features/ and immunohistochemistry
#5586
middle Confidence
Subject:
diagnosis_of_metastatic_Leydig_cell_tumor
(diagnosis)
→
can_be_made_by
→
Object:
cytomorphologic_features
(Cell morphology)
Original: Diagnosis of metastatic Leydig cell tumor#can be made by#reviewing history/ cytomorphologic features/ and immunohistochemistry
#5585
middle Confidence
Subject:
diagnosis_of_metastatic_Leydig_cell_tumor
(diagnosis)
→
can_be_made_by
→
Object:
reviewing_history
(Clinical operation)
Original: Diagnosis of metastatic Leydig cell tumor#can be made by#reviewing history/ cytomorphologic features/ and immunohistochemistry
#5576
middle Confidence
Subject:
exocrine_pancreatic_tumors
(Tumor type)
→
are_of
→
Object:
ductal_origin
(Organization Source)
Original: Most exocrine pancreatic tumors#are of#ductal origin
#5556
middle Confidence
Subject:
nestin
(Intermediate filament protein)
→
stained_negative_in
→
Object:
melanocytes
(Pigment cells)
Original: Melanocytes#stained negative for#nestin
#5555
middle Confidence
Subject:
HMB-45
(melanin-related antigen)
→
stained_negative_in
→
Object:
melanocytes
(Pigment cells)
Original: Melanocytes#stained negative for#HMB-45
#5554
middle Confidence
Subject:
p16
(Cyclin inhibitors)
→
stained_positive_in
→
Object:
melanocytes
(Pigment cells)
Original: Melanocytes#stained positive for#p16
#5551
middle Confidence
Subject:
superior_vena_cava_syndrome
(Disease phenotype)
→
had_features_of
→
Object:
right-sided_pleural_effusion
(symptom)
Original: Patient#had features of#superior vena cava syndrome with right-sided pleural effusion
#5544
middle Confidence
Subject:
histological_findings
(Histological findings)
→
show
→
Object:
meningeal_melanocytoma
(Tumor type)
Original: Histological findings#showed#a meningeal melanocytoma
#5543
middle Confidence
Subject:
findings
(Diagnostic Findings)
→
are_consistent_with
→
Object:
rhabdomyosarcoma
(Tumor type)
Original: Findings#are consistent with#a primitive sarcoma/ probably rhabdomyosarcoma
#5542
middle Confidence
Subject:
findings
(Diagnostic Findings)
→
are_consistent_with
→
Object:
primitive_sarcoma
(Tumor type)
Original: Findings#are consistent with#a primitive sarcoma/ probably rhabdomyosarcoma
#5541
middle Confidence
Subject:
cells
(cell)
→
are_positive_for
→
Object:
actin
(Cytoskeletal proteins)
Original: Cells#were positive for#vimentin and variably desmin and actin
#5540
middle Confidence
Subject:
cells
(cell)
→
are_positive_for
→
Object:
desmin
(Cytoskeletal proteins)
Original: Cells#were positive for#vimentin and variably desmin and actin
#5539
middle Confidence
Subject:
cells
(cell)
→
are_positive_for
→
Object:
vimentin
(Cytoskeletal proteins)
Original: Cells#were positive for#vimentin and variably desmin and actin
#5538
middle Confidence
Subject:
cytologic_atypia
(Cytological atypia)
→
may_result_in
→
Object:
misdiagnosis_of_pulmonary_adenocarcinoma
(Diagnostic Error)
Original: Cytologic atypia#may result in#misdiagnosis of pulmonary adenocarcinoma
#5523
middle Confidence
Subject:
cytologic_features
(Cytological characteristics)
→
were_studied_in
→
Object:
clear_cell_sarcoma
(Tumor)
Original: cytologic features#were studied#in clear cell sarcoma
#5522
middle Confidence
Subject:
cytologic_diagnosis
(Cytological diagnosis)
→
is_based_on
→
Object:
pleomorphic_cells
(Cell phenotype)
Original: cytologic diagnosis#was made#on the basis of abundant cellularity and pleomorphic cells
#5521
middle Confidence
Subject:
cytologic_diagnosis
(Cytological diagnosis)
→
is_based_on
→
Object:
abundant_cellularity
(Cell phenotype)
Original: cytologic diagnosis#was made#on the basis of abundant cellularity and pleomorphic cells
#5506
middle Confidence
Subject:
Cytology
(cytology)
→
reflects
→
Object:
premalignant_lesions
(Preneoplastic lesions)
Original: Cytology#reflects#histologic and ultrastructural changes in premalignant lesions
#5505
middle Confidence
Subject:
Cytology
(cytology)
→
reflects
→
Object:
ultrastructural_changes
(Cell ultrastructure)
Original: Cytology#reflects#histologic and ultrastructural changes in premalignant lesions
#5504
middle Confidence
Subject:
Cytology
(cytology)
→
reflects
→
Object:
histologic_changes
(Histology)
Original: Cytology#reflects#histologic and ultrastructural changes in premalignant lesions
#5408
middle Confidence
Subject:
CIS_pickup_rate
(Epidemiological indicators)
→
is_approximately
→
Object:
1_per_1000_smears
(Epidemiological data)
Original: CIS pick-up rate#is approximately#1 per 1/000 smears
#5407
middle Confidence
Subject:
diagnostic_rules
(Diagnostic rules)
→
are_derived_from
→
Object:
case_control_study_of_cervical_intraepithelial_carcinoma_in_situ
(Clinical Research)
Original: rules#are derived from#case-control study of cervical intraepithelial carcinoma in situ
#5404
middle Confidence
Subject:
nuclear_cytomorphological_features
(Nuclear morphology)
→
were_compared_between
→
Object:
HR_negative_HER2_positive_invasive_breast_cancer
(Disease classification)
Original: nuclear cytomorphological features#were compared between#HR+/HER2- and HR-/HER2+ invasive breast cancer groups
#5403
middle Confidence
Subject:
nuclear_cytomorphological_features
(Nuclear morphology)
→
were_compared_between
→
Object:
HR_positive_HER2_negative_invasive_breast_cancer
(Disease classification)
Original: nuclear cytomorphological features#were compared between#HR+/HER2- and HR-/HER2+ invasive breast cancer groups
#5363
middle Confidence
Subject:
acini
(Acinar structure)
→
composed_of
→
Object:
cells_with_pleomorphic_nuclei
(Nuclear atypia)
Original: Tumors#consisted of#acini composed of cells with pleomorphic nuclei/ loose chromatin/ evident nucleoli/ and lightly eosinophilic cytoplasm
#5362
middle Confidence
Subject:
tumors
(Tumor tissue)
→
consisted_of
→
Object:
acini
(Acinar structure)
Original: Tumors#consisted of#acini composed of cells with pleomorphic nuclei/ loose chromatin/ evident nucleoli/ and lightly eosinophilic cytoplasm
#5358
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
contain
→
Object:
large_round_or_ovoid_nuclei_with_prominent_nucleoli
(Nuclear morphology)
Original: Tumor cells#contain#large/ round/ or ovoid nuclei with prominent nucleoli
#5357
middle Confidence
Subject:
small_cells
(Tumor cells)
→
display
→
Object:
nucleoli
(Cell morphology)
Original: core biopsy imprints#showed#hypercellular smears with small cells with hyperchromatic/ round nuclei and occasional nucleoli
#5356
middle Confidence
Subject:
small_cells
(Tumor cells)
→
display
→
Object:
hyperchromatic_round_nuclei
(Cell morphology)
Original: core biopsy imprints#showed#hypercellular smears with small cells with hyperchromatic/ round nuclei and occasional nucleoli
#5355
middle Confidence
Subject:
malignant_cells
(Tumor cells)
→
display
→
Object:
prominent_nucleoli
(Cell morphology)
Original: FNAB cytology smears#showed#single and small groups of polyhedral malignant cells with granular cytoplasm/ anisokaryosis/ and prominent nucleoli
#5354
middle Confidence
Subject:
malignant_cells
(Tumor cells)
→
display
→
Object:
anisokaryosis
(Cell morphology)
Original: FNAB cytology smears#showed#single and small groups of polyhedral malignant cells with granular cytoplasm/ anisokaryosis/ and prominent nucleoli
#5353
middle Confidence
Subject:
malignant_cells
(Tumor cells)
→
display
→
Object:
granular_cytoplasm
(Cell morphology)
Original: FNAB cytology smears#showed#single and small groups of polyhedral malignant cells with granular cytoplasm/ anisokaryosis/ and prominent nucleoli
#5352
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
display
→
Object:
pleomorphic_sheets
(Cell morphology)
Original: Histologic examination#showed#sheets of pleomorphic tumor cells occupying more than one low-power field
#5292
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_difficult_to_distinguish_from
→
Object:
histiocytes
(Immune cells)
Original: Dispersed tumor cells#are difficult to distinguish from#histiocytes
#5288
middle Confidence
Subject:
diagnosis_of_lymphoepithelioma_like_carcinoma
(diagnosis)
→
is_based_on
→
Object:
microscopic_findings
(Histological manifestations)
Original: The diagnosis of lymphoepithelioma-like carcinoma#is based on#microscopic findings
#5284
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_weakly_labelled_for
→
Object:
epithelial_membrane_antigen
(Cell membrane antigen)
Original: Neoplastic cells#were weakly labelled for#chromogranin A/ synaptophysin/ Wilms' tumour 1 protein/ neuron-specific enolase/ pan-cytokeratin AE1/AE3/ and epithelial membrane antigen
#5283
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_weakly_labelled_for
→
Object:
pan_cytokeratin_AE1_AE3
(Cytoskeletal proteins)
Original: Neoplastic cells#were weakly labelled for#chromogranin A/ synaptophysin/ Wilms' tumour 1 protein/ neuron-specific enolase/ pan-cytokeratin AE1/AE3/ and epithelial membrane antigen
#5282
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_weakly_labelled_for
→
Object:
neuron_specific_enolase
(Enzymes)
Original: Neoplastic cells#were weakly labelled for#chromogranin A/ synaptophysin/ Wilms' tumour 1 protein/ neuron-specific enolase/ pan-cytokeratin AE1/AE3/ and epithelial membrane antigen
#5281
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_weakly_labelled_for
→
Object:
Wilms_tumour_1_protein
(Transcription Factors)
Original: Neoplastic cells#were weakly labelled for#chromogranin A/ synaptophysin/ Wilms' tumour 1 protein/ neuron-specific enolase/ pan-cytokeratin AE1/AE3/ and epithelial membrane antigen
#5280
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_weakly_labelled_for
→
Object:
synaptophysin
(Synaptic proteins)
Original: Neoplastic cells#were weakly labelled for#chromogranin A/ synaptophysin/ Wilms' tumour 1 protein/ neuron-specific enolase/ pan-cytokeratin AE1/AE3/ and epithelial membrane antigen
#5279
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_weakly_labelled_for
→
Object:
chromogranin_A
(Secretory proteins)
Original: Neoplastic cells#were weakly labelled for#chromogranin A/ synaptophysin/ Wilms' tumour 1 protein/ neuron-specific enolase/ pan-cytokeratin AE1/AE3/ and epithelial membrane antigen
#5278
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
were_moderately_positive_for
→
Object:
vimentin
(Cytoskeletal proteins)
Original: Neoplastic cells#were moderately positive for#vimentin
#5237
middle Confidence
Subject:
grading_system_for_breast_cancer
(Rating system)
→
is_feasible_for
→
Object:
routine_diagnostic_basis
(Diagnostic Process)
Original: Grading system for breast cancer#is feasible for#routine diagnostic basis
#5219
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
are_characterized_by
→
Object:
rounded_or_oval_shape_with_single_nucleus_and_prominent_nucleoli
(Cell morphology)
Original: Tumor cells#are characterized by#rounded or oval shape with a single nucleus and prominent nucleoli
#5193
middle Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
contain
→
Object:
prominent_nucleoli
(Nuclear characteristics)
Original: neoplastic cells#contain#prominent nucleoli
#5192
middle Confidence
Subject:
tumor
(Tumor)
→
shows
→
Object:
multinucleated_cells
(Multinucleated cells)
Original: tumor#is classified as#poorly granulated with nuclear atypia and multinucleated cells
#5191
middle Confidence
Subject:
tumor
(Tumor)
→
shows
→
Object:
nuclear_atypia
(Nuclear atypia)
Original: tumor#is classified as#poorly granulated with nuclear atypia and multinucleated cells
#5190
middle Confidence
Subject:
nuclei
(Nucleus)
→
show
→
Object:
inconspicuous_nucleoli
(Nucleolar characteristics)
Original: nuclei#show#granular chromatin/ grooves/ nuclear molding/ and inconspicuous nucleoli
#5189
middle Confidence
Subject:
nuclei
(Nucleus)
→
show
→
Object:
nuclear_molding
(Nuclear morphology)
Original: nuclei#show#granular chromatin/ grooves/ nuclear molding/ and inconspicuous nucleoli
#5188
middle Confidence
Subject:
nuclei
(Nucleus)
→
show
→
Object:
grooves
(Nuclear structural characteristics)
Original: nuclei#show#granular chromatin/ grooves/ nuclear molding/ and inconspicuous nucleoli
#5187
middle Confidence
Subject:
nuclei
(Nucleus)
→
show
→
Object:
granular_chromatin
(Nuclear chromatin characteristics)
Original: nuclei#show#granular chromatin/ grooves/ nuclear molding/ and inconspicuous nucleoli
#5186
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
show
→
Object:
follicle_like_structures
(Cell structure characteristics)
Original: tumor cells#show#giant cells/ signet ring cells/ clear cells/ intranuclear pseudoinclusions/ and follicle-like structures
#5185
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
show
→
Object:
intranuclear_pseudoinclusions
(Nuclear characteristics)
Original: tumor cells#show#giant cells/ signet ring cells/ clear cells/ intranuclear pseudoinclusions/ and follicle-like structures
#5184
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
show
→
Object:
clear_cells
(Cell subtype)
Original: tumor cells#show#giant cells/ signet ring cells/ clear cells/ intranuclear pseudoinclusions/ and follicle-like structures
#5183
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
show
→
Object:
signet_ring_cells
(Cell subtype)
Original: tumor cells#show#giant cells/ signet ring cells/ clear cells/ intranuclear pseudoinclusions/ and follicle-like structures
#5182
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
show
→
Object:
giant_cells
(Cell subtype)
Original: tumor cells#show#giant cells/ signet ring cells/ clear cells/ intranuclear pseudoinclusions/ and follicle-like structures
#5181
middle Confidence
Subject:
tumor_cells
(Tumor cells)
→
contain
→
Object:
prominent_nucleoli
(Nuclear characteristics)
Original: tumor cells#contain#prominent nucleoli
#5180
middle Confidence
Subject:
skin_metastasis
(Metastatic lesions)
→
shows
→
Object:
dermal_invasion
(Pathological process)
Original: skin metastasis#shows#superficial dissemination and dermal invasion
#5179
middle Confidence
Subject:
skin_metastasis
(Metastatic lesions)
→
shows
→
Object:
superficial_dissemination
(Pathological process)
Original: skin metastasis#shows#superficial dissemination and dermal invasion
#5144
middle Confidence
Subject:
metastatic_cervical_adenocarcinoma
(Tumor type)
→
exhibits
→
Object:
isolated_arrangement
(Histological morphology)
Original: metastatic cervical adenocarcinoma#exhibits#sheetlike or isolated arrangement
#5143
middle Confidence
Subject:
metastatic_cervical_adenocarcinoma
(Tumor type)
→
exhibits
→
Object:
sheetlike_arrangement
(Histological morphology)
Original: metastatic cervical adenocarcinoma#exhibits#sheetlike or isolated arrangement
#5119
middle Confidence
Subject:
thyroid_cold_nodule_aspirates
(Clinical samples)
→
includes
→
Object:
thyroid_cancers
(cancer)
Original: thyroid cold nodule aspirates#included#198 histologically benign/ 7 atypical adenomas/ and 52 cancers
#5118
middle Confidence
Subject:
thyroid_cold_nodule_aspirates
(Clinical samples)
→
includes
→
Object:
atypical_adenomas
(Atypical adenoma)
Original: thyroid cold nodule aspirates#included#198 histologically benign/ 7 atypical adenomas/ and 52 cancers
#5117
middle Confidence
Subject:
thyroid_cold_nodule_aspirates
(Clinical samples)
→
includes
→
Object:
histologically_benign_nodules
(Benign nodules)
Original: thyroid cold nodule aspirates#included#198 histologically benign/ 7 atypical adenomas/ and 52 cancers
#5098
middle Confidence
Subject:
small_nucleoli
(Nuclear morphology)
→
indicate
→
Object:
benign_lesion
(Disease phenotype)
Original: Many nuclei with discernible small nucleoli#indicate#a benign lesion
#5097
middle Confidence
Subject:
prominent_nucleoli
(Nuclear morphology)
→
is_not_diagnostic_of
→
Object:
malignancy
(Disease phenotype)
Original: Presence of prominent nucleoli#is not diagnostic of#malignancy
#5087
middle Confidence
Subject:
AgNOR_values
(Molecular markers)
→
are_compared_with
→
Object:
3H-dT_LI
(Molecular markers)
Original: AgNOR values#are compared with#BrdUrd and 3[H]dT LIs
#5086
middle Confidence
Subject:
AgNOR_values
(Molecular markers)
→
are_compared_with
→
Object:
BrdUrd_LI
(Molecular markers)
Original: AgNOR values#are compared with#BrdUrd and 3[H]dT LIs
#5030
middle Confidence
Subject:
FNA_of_CFA
(Cytology)
→
can_lead_to
→
Object:
erroneous_interpretation
(Diagnostic bias)
Original: FNA of CFA#can lead to#erroneous or indeterminate interpretation due to proliferative and/or hyperplastic changes of ductal epithelium
#5029
middle Confidence
Subject:
silver_staining_of_AgNORs
(Chromosomal marker testing)
→
is_evaluated_for
→
Object:
preoperative_diagnosis_of_follicular_lesions
(Diagnostic Purpose)
Original: Silver staining of nucleolar organizer regions (AgNORs)#is evaluated for#preoperative diagnosis of follicular lesions in the thyroid
#5015
middle Confidence
Subject:
Ki-67
(Cell proliferation markers)
→
analyzed_in
→
Object:
cervix_smear_with_atypical_cells
(Cytology samples)
Original: AgNORs and Ki-67 antigens expression#analyzed in#cervix and cervical canal smears with atypical cells
#5014
middle Confidence
Subject:
AgNOR
(Nucleolar organizer region-associated)
→
analyzed_in
→
Object:
cervix_smear_with_atypical_cells
(Cytology samples)
Original: AgNORs and Ki-67 antigens expression#analyzed in#cervix and cervical canal smears with atypical cells
#4981
middle Confidence
Subject:
cytologic_atypia
(Cytological abnormalities)
→
correlates_with
→
Object:
finding_of_more_serious_lesion_on_excision
(Disease phenotype)
Original: Cytologic atypia#correlates with#finding of a more serious lesion on excision
#4978
middle Confidence
Subject:
AgNOR
(Molecular markers)
→
revealed_using
→
Object:
colloid_silver_staining_technique
(Detection Methods)
Original: AgNOR#was revealed using#colloid silver staining technique in liver biopsy specimens
#4966
middle Confidence
Subject:
rhabdoid_tumor_cells
(Tumor cells)
→
include
→
Object:
inclusion_bodies_of_fibrillary_material
(Cell structure)
Original: Rhabdoid tumor cells#include#intracytoplasmatic hyaline globules/ large prominent nucleoli/ and inclusion bodies made up of whorls of fibrillary material
#4965
middle Confidence
Subject:
rhabdoid_tumor_cells
(Tumor cells)
→
include
→
Object:
large_prominent_nucleoli
(Cell structure)
Original: Rhabdoid tumor cells#include#intracytoplasmatic hyaline globules/ large prominent nucleoli/ and inclusion bodies made up of whorls of fibrillary material
#4964
middle Confidence
Subject:
rhabdoid_tumor_cells
(Tumor cells)
→
include
→
Object:
intracytoplasmatic_hyaline_globules
(Cell structure)
Original: Rhabdoid tumor cells#include#intracytoplasmatic hyaline globules/ large prominent nucleoli/ and inclusion bodies made up of whorls of fibrillary material
#4938
middle Confidence
Subject:
Granulosa_cell_tumors
(Thecoma)
→
has_ultrastructural_features_of
→
Object:
granulosa_cells
(Theca cells)
Original: Ultrastructural features of granulosa cell tumors#are presented#
#4894
middle Confidence
Subject:
Synaptophysin
(Synaptic vesicle protein)
→
shows_sparse_immunoreaction_in
→
Object:
Extrapulmonary_small_cell_carcinoma
(Tumor diseases)
Original: Sparse immunoreaction#was seen for#synaptophysin
#4886
middle Confidence
Subject:
skin_biopsy
(Organization and collection method)
→
reveals
→
Object:
dermal_neoplasm_composed_of_epithelioid_cells
(Tumor morphological characteristics)
Original: Skin biopsy#revealed#a dermal and subcutaneous neoplasm composed of spindle and epithelioid cells
#4885
middle Confidence
Subject:
skin_biopsy
(Organization and collection method)
→
reveals
→
Object:
dermal_neoplasm_composed_of_spindle_cells
(Tumor morphological characteristics)
Original: Skin biopsy#revealed#a dermal and subcutaneous neoplasm composed of spindle and epithelioid cells
#4879
middle Confidence
Subject:
pulmonary_wedge_aspiration_cytology
(Pathological technology)
→
is_performed_on
→
Object:
pulmonary_artery
(Vascular structure)
Original: Pulmonary wedge aspiration cytology#was performed#on pulmonary artery during catheterization
#4874
middle Confidence
Subject:
metastatic_malignant_melanoma
(Metastatic tumors)
→
was_present_in
→
Object:
neo-bladder_urine
(Body fluid specimens)
Original: Metastatic malignant melanoma#was present in#neo-bladder urine
#4816
middle Confidence
Subject:
acini
(Acinar structure)
→
composed_of
→
Object:
cells_with_lightly_eosinophilic_cytoplasm
(Cytoplasmic eosinophilic)
Original: Tumors#consisted of#acini composed of cells with pleomorphic nuclei/ loose chromatin/ evident nucleoli/ and lightly eosinophilic cytoplasm
#4815
middle Confidence
Subject:
acini
(Acinar structure)
→
composed_of
→
Object:
cells_with_evident_nucleoli
(Nucleolus)
Original: Tumors#consisted of#acini composed of cells with pleomorphic nuclei/ loose chromatin/ evident nucleoli/ and lightly eosinophilic cytoplasm
#4814
middle Confidence
Subject:
acini
(Acinar structure)
→
composed_of
→
Object:
cells_with_loose_chromatin
(Sparse chromatin)
Original: Tumors#consisted of#acini composed of cells with pleomorphic nuclei/ loose chromatin/ evident nucleoli/ and lightly eosinophilic cytoplasm
#4813
middle Confidence
Subject:
tumor_cell_nuclei
(Nucleus)
→
were_characterized_by
→
Object:
clear_nuclear_membranes
(Nuclear structure)
Original: Tumor cell nuclei#were#large and round with clear nuclear membranes
#4812
middle Confidence
Subject:
tumor_cell_nuclei
(Nucleus)
→
were_characterized_by
→
Object:
large_and_round_shape
(Nuclear morphology)
Original: Tumor cell nuclei#were#large and round with clear nuclear membranes
#4811
middle Confidence
Subject:
malignant_cells
(Tumor cells)
→
Sorry, I have no idea what this is.
→
Object:
tumor_mass
(Tumor tissue)
Original: Malignant cells#occupied#approximately 70% of the mass
#4788
middle Confidence
Subject:
68-year-old_woman
(Patient characteristics)
→
had_been_diagnosed_with
→
Object:
0-IIa_type_adenocarcinoma
(Tumor diseases)
Original: 68-year-old woman#had been diagnosed with#0-IIa type adenocarcinoma
#4775
middle Confidence
Subject:
melanocytic_tumor
(Tumor type)
→
presents_as
→
Object:
black_nodules
(Clinical phenotype)
Original: These tumors#presented as#dark brown/black papules and nodules
#4774
middle Confidence
Subject:
melanocytic_tumor
(Tumor type)
→
presents_as
→
Object:
dark_brown_papules
(Clinical phenotype)
Original: These tumors#presented as#dark brown/black papules and nodules
#4765
middle Confidence
Subject:
nucleolar_type_proportion
(Cellular substructure characteristics)
→
is_analyzed_in
→
Object:
pathologic_lymphocyte_population
(Cell Type)
Original: Proportion of nucleolar types#is analyzed in#pathologic lymphocyte population
#4723
middle Confidence
Subject:
T-cell_lineage_lymphoma
(Tumor)
→
should_be_considered_if
→
Object:
rapid_progression_of_low-grade_B-cell_lymphoma
(Clinical manifestations of tumor)
Original: T-cell lineage lymphoma#should be considered if#low-grade B-cell lymphomas rapidly progress
#4656
middle Confidence
Subject:
smears
(Sample Type)
→
showed
→
Object:
vascular_cores
(Cell morphology)
Original: smears#showed#abundant papillary clusters with vascular cores
#4655
middle Confidence
Subject:
smears
(Sample Type)
→
showed
→
Object:
abundant_papillary_clusters
(Cell morphology)
Original: smears#showed#abundant papillary clusters with vascular cores
#4640
middle Confidence
Subject:
MYC
(Proto-oncogene)
→
shows_normal_result_in
→
Object:
FISH_test
(Molecular detection methods)
Original: FISH#showed#normal results for 9p21 (CDKN2A) and 8q24 (MYC)
#4639
middle Confidence
Subject:
CDKN2A
(Tumor suppressor genes)
→
shows_normal_result_in
→
Object:
FISH_test
(Molecular detection methods)
Original: FISH#showed#normal results for 9p21 (CDKN2A) and 8q24 (MYC)
#4624
middle Confidence
Subject:
Diagnosis_of_adenocarcinoma
(Diagnosis conclusion)
→
was_substantiated_by
→
Object:
signet_ring_cells
(Histological characteristics)
Original: Diagnosis of adenocarcinoma#was substantiated by#gland-like clusters of columnar epithelial cells and "signet-ring" cells
#4623
middle Confidence
Subject:
Diagnosis_of_adenocarcinoma
(Diagnosis conclusion)
→
was_substantiated_by
→
Object:
gland_like_clusters_of_columnar_epithelial_cells
(Histological characteristics)
Original: Diagnosis of adenocarcinoma#was substantiated by#gland-like clusters of columnar epithelial cells and "signet-ring" cells
#4594
middle Confidence
Subject:
tumor_cell_nuclei
(Nucleus)
→
showed
→
Object:
absence_of_nucleoli
(Nuclear structure)
Original: Tumor cell nuclei#showed#absence of nucleoli and mitotic figures of 10 per 50 high power fields
#4572
middle Confidence
Subject:
cytologic_findings
(Cytological findings)
→
correlated_with
→
Object:
clinicopathologic_variables
(Clinical pathological variables)
Original: Cytologic findings#correlated with#clinicopathologic variables
#4571
middle Confidence
Subject:
appearance_of_nucleoli
(Cell nucleolus morphology)
→
helps_in
→
Object:
diagnosis_of_small_cell_carcinoma
(Tumor type diagnosis)
Original: Appearance of nucleoli#helps in#diagnosis of lymphoma or small cell carcinoma by LM
#4570
middle Confidence
Subject:
appearance_of_nucleoli
(Cell nucleolus morphology)
→
helps_in
→
Object:
diagnosis_of_lymphoma
(Tumor type diagnosis)
Original: Appearance of nucleoli#helps in#diagnosis of lymphoma or small cell carcinoma by LM
#4569
middle Confidence
Subject:
nuclear_structure_of_tumor_cells
(Nuclear structure)
→
differentiations
→
Object:
small_cell_carcinoma
(Tumor type)
Original: Nuclear structure of tumor cells#differentiates#lymphoma from small cell carcinoma
#4568
middle Confidence
Subject:
nuclear_structure_of_tumor_cells
(Nuclear structure)
→
differentiations
→
Object:
lymphoma
(Tumor type)
Original: Nuclear structure of tumor cells#differentiates#lymphoma from small cell carcinoma
#4565
middle Confidence
Subject:
ultrastructural_peculiarities
(Cell structure characteristics)
→
serve_as
→
Object:
identifiers_of_tumor_malignity
(Diagnostic markers)
Original: Ultrastructural peculiarities#serve as#identifiers of tumor malignity and functional status
#4560
middle Confidence
Subject:
recurrent_cementoblastoma
(Tumor diseases)
→
poses
→
Object:
diagnostic_challenges
(Difficulties in diagnosis)
Original: Recurrent cementoblastoma#poses#diagnostic challenges due to cytological atypia and large size
#4536
middle Confidence
Subject:
cytological_criteria
(Diagnostic criteria)
→
refers_to
→
Object:
morphological_features_of_thyroid_cells
(Cell morphology)
Original: Cytological criteria#referred to#morphological features of thyroid cells and associated elements
#4481
middle Confidence
Subject:
nuclear_DNA_content
(Nuclear DNA content)
→
is_evaluated_in
→
Object:
bladder_TCC
(Disease phenotype)
Original: AgNOR/ nuclear DNA content/ and mean nuclear area (MNA)#are evaluated in#ureteropelvic and bladder TCCs
#4480
middle Confidence
Subject:
nuclear_DNA_content
(Nuclear DNA content)
→
is_evaluated_in
→
Object:
ureteropelvic_TCC
(Disease phenotype)
Original: AgNOR/ nuclear DNA content/ and mean nuclear area (MNA)#are evaluated in#ureteropelvic and bladder TCCs
#4479
middle Confidence
Subject:
AgNOR
(Nuclear structure markers)
→
is_evaluated_in
→
Object:
bladder_TCC
(Disease phenotype)
Original: AgNOR/ nuclear DNA content/ and mean nuclear area (MNA)#are evaluated in#ureteropelvic and bladder TCCs
#4478
middle Confidence
Subject:
AgNOR
(Nuclear structure markers)
→
is_evaluated_in
→
Object:
ureteropelvic_TCC
(Disease phenotype)
Original: AgNOR/ nuclear DNA content/ and mean nuclear area (MNA)#are evaluated in#ureteropelvic and bladder TCCs
#4467
low Confidence
Subject:
tumor
(Tumor)
→
was
→
Object:
primary_esophageal_carcinoma
(Esophageal cancer)
Original: Tumor#was#a primary esophageal carcinoma with partial adenocarcinomatous differentiation and extensive intraepithelial Pagetoid growth
#4379
low Confidence
Subject:
Nuclei
(Nucleus)
→
are_accessory_features_for
→
Object:
cytologic_interpretation_of_melanoma
(Diagnostic Process)
Original: Eccentric placement of nuclei/ nucleoli/ and nuclear pseudoinclusions#are accessory features for#cytologic interpretation of melanoma
#4378
low Confidence
Subject:
Large_cells
(Cell morphology)
→
are_included_in
→
Object:
histopathology
(Histological characteristics)
Original: Histopathology#included#large/ vacuolated cells with foamy cytoplasm and conspicuous nucleoli
#4377
low Confidence
Subject:
Nuclei
(Nucleus)
→
exhibit
→
Object:
clearer_parachromatin
(Nuclear structural characteristics)
Original: Nuclei#exhibited#thicker membranes/ more prominent nucleoli/ and clearer parachromatin
#4376
low Confidence
Subject:
Nuclei
(Nucleus)
→
exhibit
→
Object:
more_prominent_nucleoli
(Nuclear structural characteristics)
Original: Nuclei#exhibited#thicker membranes/ more prominent nucleoli/ and clearer parachromatin
#4375
low Confidence
Subject:
Nuclei
(Nucleus)
→
exhibit
→
Object:
thicker_membranes
(Nuclear structural characteristics)
Original: Nuclei#exhibited#thicker membranes/ more prominent nucleoli/ and clearer parachromatin
#4374
low Confidence
Subject:
Hyperchromatic_nuclei
(Nucleus)
→
are_characterized_by
→
Object:
shallow_longitudinal_invaginations
(Nuclear structural characteristics)
Original: Hyperchromatic nuclei#characterized#shallow longitudinal invaginations
#4373
low Confidence
Subject:
Lesions
(Lesions)
→
were_reviewed_by
→
Object:
second_dermatopathologist
(Medical professionals)
Original: Lesions#were evaluated by#one dermatopathologist and reviewed by a second
#4372
low Confidence
Subject:
Lesions
(Lesions)
→
were_evaluated_by
→
Object:
one_dermatopathologist
(Medical professionals)
Original: Lesions#were evaluated by#one dermatopathologist and reviewed by a second
#4333
low Confidence
Subject:
38-year-old_female_patient
(Patient characteristics)
→
presented_with
→
Object:
headache
(Clinical symptoms)
Original: 38-year-old female patient#presented with#headache
#4308
low Confidence
Subject:
tumor
(Tumor)
→
represented
→
Object:
distinct_subtype_of_RCC_related_to_RO
(Tumor subtype)
Original: Two tumors#likely represent#a distinct subtype of RCC related to RO
#4266
middle Confidence
Subject:
nucleolar_organizers
(Nuclear structure markers)
→
were_studied_in
→
Object:
invasive_carcinomas
(Disease phenotype)
Original: nucleolar organizers (Ag-NORs)#were studied in#ocular limbic tumors
#4265
middle Confidence
Subject:
nucleolar_organizers
(Nuclear structure markers)
→
were_studied_in
→
Object:
intraepithelial_carcinoma
(Disease phenotype)
Original: nucleolar organizers (Ag-NORs)#were studied in#ocular limbic tumors
#4264
middle Confidence
Subject:
nucleolar_organizers
(Nuclear structure markers)
→
were_studied_in
→
Object:
Bowen_disease
(Disease phenotype)
Original: nucleolar organizers (Ag-NORs)#were studied in#ocular limbic tumors
#4263
middle Confidence
Subject:
nucleolar_organizers
(Nuclear structure markers)
→
were_studied_in
→
Object:
ocular_limbic_tumors
(Disease phenotype)
Original: nucleolar organizers (Ag-NORs)#were studied in#ocular limbic tumors
#4240
low Confidence
Subject:
Malignant_mediastinal_goiter
(Tumor)
→
underwent
→
Object:
preoperative_fine-needle_aspiration_biopsy
(Diagnostic techniques)
Original: A 44-yr-old man with a preoperative diagnosis of malignant mediastinal goiter#underwent#a preoperative fine-needle aspiration biopsy
#4239
low Confidence
Subject:
GCT_of_neurohypophysis
(Tumor)
→
is_considered_under
→
Object:
spindle_cell_oncocytoma
(Tumor)
Original: GCT of the neurohypophysis#is considered under#differential diagnosis with neoplasms or lesions of histiocytic origin/ pituitocytoma/ and spindle cell oncocytoma
#4238
low Confidence
Subject:
GCT_of_neurohypophysis
(Tumor)
→
is_considered_under
→
Object:
pituitocytoma
(Tumor)
Original: GCT of the neurohypophysis#is considered under#differential diagnosis with neoplasms or lesions of histiocytic origin/ pituitocytoma/ and spindle cell oncocytoma
#4237
low Confidence
Subject:
GCT_of_neurohypophysis
(Tumor)
→
is_considered_under
→
Object:
neoplasms_of_histiocytic_origin
(Tumor)
Original: GCT of the neurohypophysis#is considered under#differential diagnosis with neoplasms or lesions of histiocytic origin/ pituitocytoma/ and spindle cell oncocytoma
#4236
low Confidence
Subject:
GCT_of_neurohypophysis
(Tumor)
→
is_considered_under
→
Object:
differential_diagnosis
(Diagnostic Process)
Original: GCT of the neurohypophysis#is considered under#differential diagnosis with neoplasms or lesions of histiocytic origin/ pituitocytoma/ and spindle cell oncocytoma
#4230
low Confidence
Subject:
needle_core_biopsy_cases_with_invasive_carcinoma
(Case)
→
showed
→
Object:
apoptosis
(Apoptosis)
Original: Needle core biopsy cases with ductal carcinoma in situ or invasive carcinoma#showed#nucleoli with nuclear pleomorphism and individual cell necrosis/apoptosis
#4229
low Confidence
Subject:
needle_core_biopsy_cases_with_invasive_carcinoma
(Case)
→
showed
→
Object:
individual_cell_necrosis
(Cell Death)
Original: Needle core biopsy cases with ductal carcinoma in situ or invasive carcinoma#showed#nucleoli with nuclear pleomorphism and individual cell necrosis/apoptosis
#4228
low Confidence
Subject:
needle_core_biopsy_cases_with_invasive_carcinoma
(Case)
→
showed
→
Object:
nucleoli_with_nuclear_pleomorphism
(Cell morphology)
Original: Needle core biopsy cases with ductal carcinoma in situ or invasive carcinoma#showed#nucleoli with nuclear pleomorphism and individual cell necrosis/apoptosis
#4227
low Confidence
Subject:
needle_core_biopsy_cases_with_ductal_carcinoma_in_situ
(Case)
→
showed
→
Object:
apoptosis
(Apoptosis)
Original: Needle core biopsy cases with ductal carcinoma in situ or invasive carcinoma#showed#nucleoli with nuclear pleomorphism and individual cell necrosis/apoptosis
#4226
low Confidence
Subject:
needle_core_biopsy_cases_with_ductal_carcinoma_in_situ
(Case)
→
showed
→
Object:
individual_cell_necrosis
(Cell Death)
Original: Needle core biopsy cases with ductal carcinoma in situ or invasive carcinoma#showed#nucleoli with nuclear pleomorphism and individual cell necrosis/apoptosis
#4225
low Confidence
Subject:
needle_core_biopsy_cases_with_ductal_carcinoma_in_situ
(Case)
→
showed
→
Object:
nucleoli_with_nuclear_pleomorphism
(Cell morphology)
Original: Needle core biopsy cases with ductal carcinoma in situ or invasive carcinoma#showed#nucleoli with nuclear pleomorphism and individual cell necrosis/apoptosis
#4215
low Confidence
Subject:
granular_cell_tumor
(Tumor)
→
have_been_documented_as
→
Object:
malignant
(Disease phenotype)
Original: Rare cases of granular cell tumor#have been documented as#malignant
#4199
low Confidence
Subject:
crusting
(Clinical manifestations)
→
appeared_with
→
Object:
primary_cutaneous_diffuse_large_B-cell_lymphoma
(Tumor)
Original: Eleven nodules#appeared with#erythematous halo/ scaling/ erosion/ and crusting
#4198
low Confidence
Subject:
erosion
(Clinical manifestations)
→
appeared_with
→
Object:
primary_cutaneous_diffuse_large_B-cell_lymphoma
(Tumor)
Original: Eleven nodules#appeared with#erythematous halo/ scaling/ erosion/ and crusting
#4197
low Confidence
Subject:
scaling
(Clinical manifestations)
→
appeared_with
→
Object:
primary_cutaneous_diffuse_large_B-cell_lymphoma
(Tumor)
Original: Eleven nodules#appeared with#erythematous halo/ scaling/ erosion/ and crusting
#4196
low Confidence
Subject:
erythematous_halo
(Clinical manifestations)
→
appeared_with
→
Object:
primary_cutaneous_diffuse_large_B-cell_lymphoma
(Tumor)
Original: Eleven nodules#appeared with#erythematous halo/ scaling/ erosion/ and crusting
#4176
low Confidence
Subject:
Three_aspirates
(sample)
→
showed
→
Object:
very_scant_cellularity_with_rare_tumor_cells
(Cytological characteristics)
Original: Three aspirates#showed#very scant cellularity with rare tumor cells originally misinterpreted as lymphohistiocytic cells
#4175
low Confidence
Subject:
breast_neoplasm
(Tumor)
→
makes
→
Object:
diagnosis_difficult
(Difficulty in diagnosis)
Original: breast neoplasm#can make#diagnosis difficult
#4173
low Confidence
Subject:
73-year-old_patient
(Patient characteristics)
→
is_diagnosed_with
→
Object:
gastric_adenocarcinoma
(Gastric adenocarcinoma)
Original: 73-year-old patient#is diagnosed with#gastric adenocarcinoma
#4172
low Confidence
Subject:
34-year-old_woman
(Patient characteristics)
→
is_diagnosed_with
→
Object:
breast_AciCC
(Adenoid cystic carcinoma of the breast)
Original: 34-year-old woman#is diagnosed with#breast AciCC
#4171
low Confidence
Subject:
HOSE_cells
(Cell Type)
→
are_defined_as
→
Object:
baseline_features_important_to_pathologists_and_clinicians
(Cytological characteristics)
Original: HOSE cells#are defined as#baseline features important to pathologists and clinicians evaluating ovarian epithelial cancer
#4133
low Confidence
Subject:
nephrogenic_adenoma
(Adenoma)
→
is_reviewed_for
→
Object:
malignant_mimics
(Tumor)
Original: nephrogenic adenoma#is reviewed for#diagnostic criteria and malignant mimics
#4127
low Confidence
Subject:
radical_thymectomy
(Surgery)
→
revealed
→
Object:
stage_III_thymic_carcinoma_with_rhabdoid_component
(Solid Tumors)
Original: Radical thymectomy#revealed#stage III thymic carcinoma with rhabdoid component
#4051
low Confidence
Subject:
prominent_nucleoli
(Nucleolar morphology)
→
are_observed_in
→
Object:
benign_mimickers
(Benign phenotype)
Original: Prominent nucleoli#are observed in#prostatic carcinoma and benign mimickers
#3935
low Confidence
Subject:
inflammatory_pseudotumor
(disease)
→
occurs_in
→
Object:
Sorry, I have no idea what this means.
(organ)
Original: Inflammatory pseudotumor (IPT)#occurred in#the spleen of a 77-year-old woman
#3907
low Confidence
Subject:
remaining_features
(Feature Collection)
→
improved
→
Object:
diagnostic_performance
(Diagnostic capabilities)
Original: Results with remaining features#were#slightly better
#3897
low Confidence
Subject:
grayish_tan_fish-flesh_mass
(Tumor Entities)
→
was_present_in
→
Object:
pancreatic_tail
(Organ location)
Original: A well-defined grayish tan fish-flesh mass#was present in#the pancreatic tail
#3896
low Confidence
Subject:
65-year-old_woman
(Patient characteristics)
→
presented_with
→
Object:
chest_pain
(Clinical symptoms)
Original: 65-year-old woman#presented with#a 2-month history of abdominal and chest pain
#3895
low Confidence
Subject:
65-year-old_woman
(Patient characteristics)
→
presented_with
→
Object:
abdominal_pain
(Clinical symptoms)
Original: 65-year-old woman#presented with#a 2-month history of abdominal and chest pain
#3851
low Confidence
Subject:
A_64_year_old_man
(patient)
→
presented_with
→
Object:
lip_lesion_diagnosed_as_squamous_cell_carcinoma
(Disease phenotype)
Original: A 64-year-old man#presented with#a lip lesion clinically diagnosed as keratoacanthoma vs. squamous cell carcinoma
#3850
low Confidence
Subject:
A_64_year_old_man
(patient)
→
presented_with
→
Object:
lip_lesion_diagnosed_as_keratoacanthoma
(Disease phenotype)
Original: A 64-year-old man#presented with#a lip lesion clinically diagnosed as keratoacanthoma vs. squamous cell carcinoma
#3849
low Confidence
Subject:
metastatic_neuroendocrine_disease
(Tumor type)
→
should_prompt
→
Object:
careful_review_of_clinical_history
(Diagnostic Process)
Original: Multiple breast lesions#should prompt#careful review of the patient's clinical history
#3848
low Confidence
Subject:
breast_lesions
(Tumor type)
→
should_prompt
→
Object:
careful_review_of_clinical_history
(Diagnostic Process)
Original: Multiple breast lesions#should prompt#careful review of the patient's clinical history
#3847
low Confidence
Subject:
Oligodendroglialike_cells_of_DNT
(Tumor cells)
→
were_distinguished_from
→
Object:
oligodendrogliomas
(Tumor type)
Original: Oligodendroglialike cells of DNT#were distinguished from#oligodendrogliomas by larger nuclei with frequent nuclear indentation and multiple/ small nucleoli
#3818
low Confidence
Subject:
tumor
(Tumor)
→
resembles
→
Object:
haemangioma
(Benign tumors)
Original: tumor#resembled#a haemangioma clinically
#3777
low Confidence
Subject:
patient
(patient)
→
presented_with
→
Object:
erythema
(Disease phenotype)
Original: patient#presented with#an enlarging nevus on the right flank with surrounding erythema
#3776
low Confidence
Subject:
patient
(patient)
→
presented_with
→
Object:
enlarging_nevus
(Disease phenotype)
Original: patient#presented with#an enlarging nevus on the right flank with surrounding erythema
#3734
low Confidence
Subject:
adenocarcinoma
(Tumor diseases)
→
should_be_included_in
→
Object:
differential_diagnosis
(Diagnostic Process)
Original: Endodermal sinus tumor#should be included in#differential diagnosis when cytologic features resemble adenocarcinoma
#3733
low Confidence
Subject:
endodermal_sinus_tumor
(Tumor diseases)
→
should_be_included_in
→
Object:
differential_diagnosis
(Diagnostic Process)
Original: Endodermal sinus tumor#should be included in#differential diagnosis when cytologic features resemble adenocarcinoma
#3726
low Confidence
Subject:
electron_microscopy
(Technical methods)
→
revealed
→
Object:
absence_of_epithelial_cells
(Histological characteristics)
Original: electron microscopy#revealed#no epithelial cells in 82 malignant lymphomas except 2 cases
#3725
low Confidence
Subject:
adenoma_malignum
(Tumor type)
→
showed
→
Object:
cystic_dilation
(Histological characteristics)
Original: adenoma malignum#showed#a cumuliform pattern and cystic dilation
#3724
low Confidence
Subject:
adenoma_malignum
(Tumor type)
→
showed
→
Object:
cumuliform_pattern
(Histological characteristics)
Original: adenoma malignum#showed#a cumuliform pattern and cystic dilation
#3710
low Confidence
Subject:
familiarity_with_cytomorphology
(Diagnostic knowledge)
→
may_facilitate
→
Object:
detection_in_urine_cytology_specimens
(Diagnostic Process)
Original: Familiarity with cytomorphology#may facilitate#detection in urine cytology specimens
#3630
low Confidence
Subject:
atypical_features
(Cell morphology)
→
includes
→
Object:
occasional_mitotic_figures
(Cell division characteristics)
Original: Atypical features#include#occasional mitotic figures
#3629
low Confidence
Subject:
atypical_features
(Cell morphology)
→
includes
→
Object:
small_nucleoli
(Cell structure)
Original: Atypical features#include#small nucleoli
#3628
low Confidence
Subject:
atypical_features
(Cell morphology)
→
includes
→
Object:
increased_nucleo-cytoplasmic_ratio
(Cell morphology index)
Original: Atypical features#include#increased nucleo-cytoplasmic ratio
#3609
low Confidence
Subject:
Spindle (sarcomatoid) C-ALCL cases
(Tumor type)
→
were_presented_with
→
Object:
molecular data
(Molecular data)
Original: Spindle (sarcomatoid) C-ALCL cases#were presented with#comprehensive histopathologic/ immunophenotypic/ and molecular data
#3608
low Confidence
Subject:
Spindle (sarcomatoid) C-ALCL cases
(Tumor type)
→
were_presented_with
→
Object:
Immunophenotypic data
(Immunophenotyping data)
Original: Spindle (sarcomatoid) C-ALCL cases#were presented with#comprehensive histopathologic/ immunophenotypic/ and molecular data
#3607
low Confidence
Subject:
Spindle (sarcomatoid) C-ALCL cases
(Tumor type)
→
were_presented_with
→
Object:
histopathologic data
(Pathological data)
Original: Spindle (sarcomatoid) C-ALCL cases#were presented with#comprehensive histopathologic/ immunophenotypic/ and molecular data
#3606
low Confidence
Subject:
Pituitary samples
(Tissue samples)
→
showed
→
Object:
brisk mitotic activity
(Cellular Processes)
Original: Pituitary samples#showed#brisk mitotic activity/ high Ki-67/ and p53 immunolabelling
#3593
low Confidence
Subject:
osteogenic_sarcoma_chondroblastic_type
(Osteosarcoma subtypes)
→
was_interpreted_as
→
Object:
chondrosarcoma
(Chondrosarcoma)
Original: osteogenic sarcoma/ chondroblastic type#was interpreted as#chondrosarcoma
#3556
low Confidence
Subject:
cytologic_features_of_CCS
(Cytological characteristics)
→
were_described_in
→
Object:
exfoliative_specimens
(Test sample type)
Original: cytologic features of CCS#were described#in FNAB and exfoliative specimens
#3555
low Confidence
Subject:
cytologic_features_of_CCS
(Cytological characteristics)
→
were_described_in
→
Object:
FNAB_specimens
(Test sample type)
Original: cytologic features of CCS#were described#in FNAB and exfoliative specimens
#3554
low Confidence
Subject:
negative_cytology
(Cytology test results)
→
was_observed_in
→
Object:
13_of_78_cases
(Case statistics)
Original: 13/78 cases#showed#negative cytology
#3529
low Confidence
Subject:
Clinical_exam_findings
(Clinical manifestations)
→
include
→
Object:
ulcerated_lesions_larger_than_1cm_in_lower_extremities
(Disease phenotype)
Original: Clinical exam findings#included#raised/ ulcerated lesions larger than 1 cm in the lower extremities
#3528
low Confidence
Subject:
Clinical_exam_findings
(Clinical manifestations)
→
include
→
Object:
raised_lesions
(Disease phenotype)
Original: Clinical exam findings#included#raised/ ulcerated lesions larger than 1 cm in the lower extremities
#3527
low Confidence
Subject:
Cytoplasmic_vacuoles
(Cytoplasmic vacuoles)
→
are_evident_in
→
Object:
Wright's-stained_smears
(Staining samples)
Original: Erythrophagocytosis and cytoplasmic vacuoles#were evident in#Wright's-stained smears
#3526
low Confidence
Subject:
Erythrophagocytosis
(Cell phagocytosis)
→
is_evident_in
→
Object:
Wright's-stained_smears
(Staining samples)
Original: Erythrophagocytosis and cytoplasmic vacuoles#were evident in#Wright's-stained smears
#3525
low Confidence
Subject:
Single_nuclei
(Nucleus)
→
project_from
→
Object:
cell_groups_in_Papanicolaou-stained_smears
(Cell population)
Original: Single nuclei#projected from#cell groups in Papanicolaou-stained smears
#3524
low Confidence
Subject:
Aggregates_of_cells
(Cell aggregation)
→
predominate_in
→
Object:
aspirate_from_well-differentiated_tumor
(Tumor samples)
Original: Aggregates of two to ten cells#predominated in#aspirate from the well-differentiated tumor
#3490
low Confidence
Subject:
Differential_diagnosis
(Differential Diagnosis)
→
includes
→
Object:
metastasis_to_breast
(Transfer)
Original: Differential diagnosis#includes#high-grade ductal carcinoma/ lymphoma/ or metastasis to breast or intramammary lymph nodes
#3489
low Confidence
Subject:
Differential_diagnosis
(Differential Diagnosis)
→
includes
→
Object:
lymphoma
(Lymphoma)
Original: Differential diagnosis#includes#high-grade ductal carcinoma/ lymphoma/ or metastasis to breast or intramammary lymph nodes
#3488
low Confidence
Subject:
Differential_diagnosis
(Differential Diagnosis)
→
includes
→
Object:
high-grade_ductal_carcinoma
(Breast cancer subtypes)
Original: Differential diagnosis#includes#high-grade ductal carcinoma/ lymphoma/ or metastasis to breast or intramammary lymph nodes
#3476
low Confidence
Subject:
65-year-old_postmenopausal_Japanese_female
(Patient characteristics)
→
presented_with
→
Object:
abnormal_genital_bleeding
(symptom)
Original: 65-year-old postmenopausal Japanese female#presented with#abnormal genital bleeding
#3435
low Confidence
Subject:
disc_herniation
(Herniated disc)
→
was_suspected_at
→
Object:
S
(Anatomical location)
Original: disc herniation#was suspected at#L5 and S
#3434
low Confidence
Subject:
FDC
(Follicular dendritic cells)
→
recognized_by
→
Object:
other_features
(Cell characteristics)
Original: FDC#can be recognized by#distinct central nucleolus and other features
#3422
low Confidence
Subject:
small cell anaplastic carcinoma of the prostate
(Tumor type)
→
was_diagnosed_in
→
Object:
patient
(patient)
Original: Small cell anaplastic carcinoma of the prostate#was diagnosed in#a patient
#3401
low Confidence
Subject:
case
(Case)
→
classified_as
→
Object:
Leiomyoblastoma
(Tumor subtype)
Original: cases#classified as#49 leiomyoma/ 51 leiomyosarcoma/ and 2 leiomyoblastoma
#3262
low Confidence
Subject:
Nucleoli
(Nucleolus)
→
are_evaluated_for
→
Object:
Cytological criteria
(Diagnostic criteria)
Original: Nucleoli#are evaluated for#cytological criteria
#3243
low Confidence
Subject:
clues_for_recognizing_partial_atrophy
(Diagnostic Tips)
→
include
→
Object:
pale_cytoplasm
(Cell characteristics)
Original: clues#for recognizing partial atrophy include#scant cytoplasm/ crinkled nuclei/ pale cytoplasm
#3242
low Confidence
Subject:
clues_for_recognizing_partial_atrophy
(Diagnostic Tips)
→
include
→
Object:
crinkled_nuclei
(Cell characteristics)
Original: clues#for recognizing partial atrophy include#scant cytoplasm/ crinkled nuclei/ pale cytoplasm
#3241
low Confidence
Subject:
clues_for_recognizing_partial_atrophy
(Diagnostic Tips)
→
include
→
Object:
scant_cytoplasm
(Cell characteristics)
Original: clues#for recognizing partial atrophy include#scant cytoplasm/ crinkled nuclei/ pale cytoplasm
#3240
low Confidence
Subject:
basal_cells
(Basal cells)
→
are_not_identifiable_in
→
Object:
partial_atrophy_cases
(Case)
Original: basal cells#are not identifiable in#27.4% of cases
#3239
low Confidence
Subject:
irregular_nuclei
(Abnormal nuclear structure)
→
are_frequent_in
→
Object:
partial_atrophy_cases
(Case)
Original: irregular nuclei#are frequent in#23.5% of partial atrophy cases
#3153
low Confidence
Subject:
distinguishing_features
(Histological characteristics)
→
include
→
Object:
Necrosis
(Histological characteristics)
Original: distinguishing features#included#prominent nucleoli/ coarse chromatin/ mitosis/ necrosis
#3152
low Confidence
Subject:
distinguishing_features
(Histological characteristics)
→
include
→
Object:
Mitosis
(Cellular Processes)
Original: distinguishing features#included#prominent nucleoli/ coarse chromatin/ mitosis/ necrosis
#3151
low Confidence
Subject:
distinguishing_features
(Histological characteristics)
→
include
→
Object:
coarse_chromatin
(Nuclear characteristics)
Original: distinguishing features#included#prominent nucleoli/ coarse chromatin/ mitosis/ necrosis
#3150
low Confidence
Subject:
distinguishing_features
(Histological characteristics)
→
include
→
Object:
prominent_nucleoli
(Nuclear characteristics)
Original: distinguishing features#included#prominent nucleoli/ coarse chromatin/ mitosis/ necrosis
#3129
low Confidence
Subject:
non-GCB_phenotype
(Molecular subtypes)
→
is_observed_in
→
Object:
IVLBCL_case
(Case)
Original: 5 cases#are characterized by#1 GCB phenotype and 4 non-GCB phenotypes
#3128
low Confidence
Subject:
GCB_phenotype
(Molecular subtypes)
→
is_observed_in
→
Object:
IVLBCL_case
(Case)
Original: 5 cases#are characterized by#1 GCB phenotype and 4 non-GCB phenotypes
#3127
low Confidence
Subject:
Follicular_dendritic_cell_tumor
(Tumor type)
→
merits
→
Object:
wider_recognition_for_extranodal_occurrence
(Clinical manifestations)
Original: Follicular dendritic cell tumor#merits#wider recognition for extranodal occurrence and full morphological spectrum
#3113
low Confidence
Subject:
fine_needle_aspirates
(Diagnostic techniques)
→
were_examined_for
→
Object:
chromatin_granularity
(Chromatin characteristics)
Original: Fine needle aspirates#were examined for#necrosis/ nuclear/cytoplasmic ratio/ and chromatin granularity
#3112
low Confidence
Subject:
fine_needle_aspirates
(Diagnostic techniques)
→
were_examined_for
→
Object:
nuclear_cytoplasmic_ratio
(Nuclear characteristics)
Original: Fine needle aspirates#were examined for#necrosis/ nuclear/cytoplasmic ratio/ and chromatin granularity
#3111
low Confidence
Subject:
fine_needle_aspirates
(Diagnostic techniques)
→
were_examined_for
→
Object:
Necrosis
(Histopathological characteristics)
Original: Fine needle aspirates#were examined for#necrosis/ nuclear/cytoplasmic ratio/ and chromatin granularity
#3110
low Confidence
Subject:
neoplasm
(Tumor)
→
was_interpreted_as
→
Object:
primitive_neuroectodermal_tumor
(Tumor type)
Original: Neoplasm#was interpreted as#a mixed mesenchymal and primitive neuroectodermal tumor (PNET)
#3109
low Confidence
Subject:
neoplasm
(Tumor)
→
was_interpreted_as
→
Object:
mixed_mesenchymal_tumor
(Tumor type)
Original: Neoplasm#was interpreted as#a mixed mesenchymal and primitive neuroectodermal tumor (PNET)
#3105
low Confidence
Subject:
light_and_ultrastructural_features
(Morphological characteristics)
→
characterize
→
Object:
lymphoma
(Tumor type)
Original: EM specimens#were reviewed for#light and ultrastructural features of small cell carcinoma and lymphoma
#3104
low Confidence
Subject:
light_and_ultrastructural_features
(Morphological characteristics)
→
characterize
→
Object:
small_cell_carcinoma
(Tumor type)
Original: EM specimens#were reviewed for#light and ultrastructural features of small cell carcinoma and lymphoma
#3082
low Confidence
Subject:
renal_neoplasms
(Tumor type)
→
are_characterized_by
→
Object:
oncocytic_cytoplasm
(Cell morphology)
Original: Neoplasms#are characterized by#oncocytic cytoplasm/ intra-cytoplasmic vacuoles/ hyperchromatic nuclei/ and prominent nucleoli
#3081
low Confidence
Subject:
renal_neoplasms
(Tumor type)
→
are_reported_with
→
Object:
similar_histopathological_appearances
(Histological characteristics)
Original: Two renal neoplasms#are reported with#similar histopathological appearances
#3041
low Confidence
Subject:
fine_needle_aspiration_cytology
(Cytological techniques)
→
was_performed_for
→
Object:
diagnosis
(Diagnostic behavior)
Original: Fine needle aspiration cytology#was performed for#diagnosis
#2979
low Confidence
Subject:
Patients
(patient)
→
present_with
→
Object:
firm_painless_intramuscular_mass
(Clinical symptoms)
Original: Patients#present with#firm/ painless intramuscular mass
#2975
low Confidence
Subject:
craniopharyngiomas
(Tumor type)
→
included
→
Object:
clinical_features
(Clinical characteristics)
Original: Observations of craniopharyngiomas#included#morphological/ biochemical/ ultrastructural/ tissue culture and clinical features
#2973
low Confidence
Subject:
craniopharyngiomas
(Tumor type)
→
included
→
Object:
ultrastructural_features
(Ultrastructural characteristics)
Original: Observations of craniopharyngiomas#included#morphological/ biochemical/ ultrastructural/ tissue culture and clinical features
#2972
low Confidence
Subject:
craniopharyngiomas
(Tumor type)
→
included
→
Object:
biochemical_features
(Biochemical characteristics)
Original: Observations of craniopharyngiomas#included#morphological/ biochemical/ ultrastructural/ tissue culture and clinical features
#2971
low Confidence
Subject:
craniopharyngiomas
(Tumor type)
→
included
→
Object:
morphological_features
(Histological characteristics)
Original: Observations of craniopharyngiomas#included#morphological/ biochemical/ ultrastructural/ tissue culture and clinical features
#2895
low Confidence
Subject:
tumor_cells_in_lymph_nodes
(Tumor cells)
→
show
→
Object:
prominent_nucleoli
(Nuclear morphology)
Original: Tumor cells in lymph nodes#have#abundant cytoplasm/ large irregular nuclei/ and prominent nucleoli
#2683
low Confidence
Subject:
pancreatic_metastasis
(Metastatic phenotype)
→
reported_in
→
Object:
primary_gastric_melanoma
(Tumor)
Original: Case#reported as#primary gastric melanoma with pancreatic metastasis
#2682
low Confidence
Subject:
primary_gastric_melanoma
(Tumor)
→
reported_as
→
Object:
pancreatic_metastasis
(Metastatic phenotype)
Original: Case#reported as#primary gastric melanoma with pancreatic metastasis
#2655
low Confidence
Subject:
diagnosis
(Diagnostic behavior)
→
depends_on
→
Object:
pathologist_awareness
(Pathology knowledge)
Original: Correct diagnosis#depends on#pathologist awareness and histopathological evaluation
#2513
low Confidence
Subject:
77-year-old_woman
(Patient characteristics)
→
presented_with
→
Object:
lesion_on_left_lower_eyelid
(Clinical symptoms)
Original: 77-year-old woman#presented with#a 3-month history of a lesion on her left lower eyelid
#2509
low Confidence
Subject:
patient
(Patient characteristics)
→
presented_with
→
Object:
headache
(Clinical symptoms)
Original: a 36-yr-old woman#presented with#a 3-week history of headache
#2500
low Confidence
Subject:
Spindle_C-ALCL
(Tumor subtype)
→
represented
→
Object:
potential_mimicker_of_malignant_hematopoietic_tumors
(Tumor type)
Original: Spindle C-ALCL#represents#a potential mimicker of malignant mesenchymal or hematopoietic tumors in the skin
#2499
low Confidence
Subject:
Spindle_C-ALCL
(Tumor subtype)
→
represented
→
Object:
potential_mimicker_of_malignant_mesenchymal_tumors
(Tumor type)
Original: Spindle C-ALCL#represents#a potential mimicker of malignant mesenchymal or hematopoietic tumors in the skin
#2454
low Confidence
Subject:
bronchial_brush_cytology_material
(Technical Materials)
→
was_stained_with
→
Object:
neural_cell_adhesion_molecule_antibody
(Antibody)
Original: bronchial brush cytology material#was stained with#PGP9.5/ neuron-specific enolase/ and neural cell adhesion molecule antibodies
#2453
low Confidence
Subject:
bronchial_brush_cytology_material
(Technical Materials)
→
was_stained_with
→
Object:
neuron-specific_enolase_antibody
(Antibody)
Original: bronchial brush cytology material#was stained with#PGP9.5/ neuron-specific enolase/ and neural cell adhesion molecule antibodies
#2452
low Confidence
Subject:
bronchial_brush_cytology_material
(Technical Materials)
→
was_stained_with
→
Object:
PGP9.5_antibody
(Antibody)
Original: bronchial brush cytology material#was stained with#PGP9.5/ neuron-specific enolase/ and neural cell adhesion molecule antibodies
#2388
low Confidence
Subject:
fusiform_cells
(Cell Type)
→
contain
→
Object:
clear_cytoplasm
(Cell structure)
Original: polygonal or fusiform cells#contain#clear cytoplasm
#2387
low Confidence
Subject:
polygonal_cells
(Cell Type)
→
contain
→
Object:
clear_cytoplasm
(Cell structure)
Original: polygonal or fusiform cells#contain#clear cytoplasm
#2386
low Confidence
Subject:
FNA_cell_block_sections
(Tissue sections)
→
contain
→
Object:
fusiform_cells
(Cell Type)
Original: FNA cell block sections#contain#polygonal or fusiform cells
#2385
low Confidence
Subject:
FNA_cell_block_sections
(Tissue sections)
→
contain
→
Object:
polygonal_cells
(Cell Type)
Original: FNA cell block sections#contain#polygonal or fusiform cells
#2384
low Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
contain
→
Object:
eccentric_nucleus
(Nuclear characteristics)
Original: neoplastic cells#contain#an eccentric nucleus
#2383
low Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
contain
→
Object:
large_cytoplasmic_vacuole
(Cell structure)
Original: neoplastic cells#contain#a large cytoplasmic vacuole
#2382
low Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
show
→
Object:
diminished_plicae
(Cell ultrastructure)
Original: neoplastic cells#show#diminished surface microridges and plicae
#2381
low Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
show
→
Object:
diminished_surface_microridges
(Cell ultrastructure)
Original: neoplastic cells#show#diminished surface microridges and plicae
#2380
low Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
appear_as
→
Object:
rounded_distended_structures
(Cell morphology)
Original: neoplastic cells#appear as#rounded/ distended structures
#2379
low Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
contain
→
Object:
hyperchromatic_nuclei
(Nuclear characteristics)
Original: neoplastic cells#contain#hyperchromatic nuclei
#2378
low Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
contain
→
Object:
large_secretory_vacuoles
(Cell structure)
Original: neoplastic cells#contain#large secretory vacuoles
#2377
low Confidence
Subject:
primary_adenocarcinoma_of_urinary_bladder
(Tumor type)
→
included
→
Object:
ultrastructural_studies
(Ultrastructural examination)
Original: Case of primary adenocarcinoma of urinary bladder#included#histologic/ cytologic/ and ultrastructural studies
#2376
low Confidence
Subject:
primary_adenocarcinoma_of_urinary_bladder
(Tumor type)
→
included
→
Object:
cytologic_studies
(Cytology)
Original: Case of primary adenocarcinoma of urinary bladder#included#histologic/ cytologic/ and ultrastructural studies
#2375
low Confidence
Subject:
primary_adenocarcinoma_of_urinary_bladder
(Tumor type)
→
included
→
Object:
histologic_studies
(Histological examination)
Original: Case of primary adenocarcinoma of urinary bladder#included#histologic/ cytologic/ and ultrastructural studies
#2374
low Confidence
Subject:
Adenocarcinoma_of_urinary_bladder
(Tumor type)
→
was_analyzed_for
→
Object:
ultrastructural_features
(Ultrastructural characteristics)
Original: Adenocarcinoma of urinary bladder#was analyzed for#histologic/ cytologic/ and ultrastructural features
#2373
low Confidence
Subject:
Adenocarcinoma_of_urinary_bladder
(Tumor type)
→
was_analyzed_for
→
Object:
cytologic_features
(Cytological characteristics)
Original: Adenocarcinoma of urinary bladder#was analyzed for#histologic/ cytologic/ and ultrastructural features
#2372
low Confidence
Subject:
Adenocarcinoma_of_urinary_bladder
(Tumor type)
→
was_analyzed_for
→
Object:
histologic_features
(Histological characteristics)
Original: Adenocarcinoma of urinary bladder#was analyzed for#histologic/ cytologic/ and ultrastructural features
#2326
low Confidence
Subject:
differentiation_of_SBT_from_grade_1_SCA
(Diagnostic Process)
→
is_not_reliable
→
Object:
differential_diagnosis
(Diagnostic recommendations)
Original: Differentiation of SBT from grade 1 SCA#is not reliable#meriting a differential diagnosis
#2318
low Confidence
Subject:
extracutaneous_melanoma
(disease)
→
should_be_considered_in
→
Object:
undifferentiated_neoplasms_with_prominent_nucleoli
(Tumor morphological characteristics)
Original: Extracutaneous melanoma#should be considered in#undifferentiated neoplasms with prominent nucleoli
#2314
low Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
is_discussed_between
→
Object:
small_cell_neoplasms
(Tumor type)
Original: Differential diagnosis#is discussed between#Ewing's sarcoma and other small-cell neoplasms
#2313
low Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
is_discussed_between
→
Object:
ewings_sarcoma
(Tumor type)
Original: Differential diagnosis#is discussed between#Ewing's sarcoma and other small-cell neoplasms
#2273
low Confidence
Subject:
blue_tinged_mucinous_secretion
(Blue-stained mucous secretion)
→
is_not_identified_in
→
Object:
partial_atrophy
(Pathological changes)
Original: no intraluminal crystalloids or blue-tinged mucinous secretion#is identified in#partial atrophy
#2272
low Confidence
Subject:
intraluminal_crystalloids
(Glandular crystals)
→
are_not_identified_in
→
Object:
partial_atrophy
(Pathological changes)
Original: no intraluminal crystalloids or blue-tinged mucinous secretion#is identified in#partial atrophy
#2225
low Confidence
Subject:
linear_discriminant_analysis
(Analytical methods)
→
obtained
→
Object:
correct_classification
(Diagnosis)
Original: All parameters combined in linear discriminant analysis#obtained#correct classification in 48 out of 57 cases
#2219
low Confidence
Subject:
Eight_patients
(patient)
→
presented_with
→
Object:
primary_cutaneous_tumors
(Disease phenotype)
Original: Eight patients#presented with#primary cutaneous tumors at various sites
#2195
low Confidence
Subject:
Woman
(patient)
→
is_diagnosed_with
→
Object:
histiocytoid feature
(Histological characteristics)
Original: Women#are diagnosed with#invasive lobular carcinoma with histiocytoid features
#2175
low Confidence
Subject:
cytological_criteria
(Diagnostic criteria)
→
refers_to
→
Object:
associated_elements
(Related cell components)
Original: Cytological criteria#referred to#morphological features of thyroid cells and associated elements
#2075
low Confidence
Subject:
melanocytic_neoplasm
(Tumor tissue)
→
is_observed_in
→
Object:
skin_biopsy_specimen
(Tissue samples)
Original: Melanocytic neoplasms with prominent pigment synthesis#are observed in#skin and lymph node biopsy specimens
#2028
low Confidence
Subject:
centroblastic_lymphoma
(Tumor)
→
cannot_rule_out
→
Object:
T-cell_lymphoma
(Tumor)
Original: centroblastic lymphoma examples#cannot rule out#T-cell lymphoma
#2027
low Confidence
Subject:
nucleoli
(Nuclear structure)
→
should_be_taken_in_context_with
→
Object:
architectural_features
(Organizational structure characteristics)
Original: significance of nucleoli#should be taken in context with#cytologic and architectural features
#2026
low Confidence
Subject:
nucleoli
(Nuclear structure)
→
should_be_taken_in_context_with
→
Object:
cytologic_features
(Cell morphology)
Original: significance of nucleoli#should be taken in context with#cytologic and architectural features
#2016
low Confidence
Subject:
case
(Case)
→
was_misdiagnosed_as
→
Object:
anaplastic_carcinoma
(Tumor)
Original: Three cases#were misdiagnosed as#anaplastic carcinoma of the small-cell type
#2015
low Confidence
Subject:
case
(Case)
→
was_diagnosed_as
→
Object:
malignant_lymphoma
(Tumor)
Original: One case#was diagnosed as#malignant lymphoma
#2006
low Confidence
Subject:
pathologic_features
(Pathological characteristics)
→
correlated_with
→
Object:
excision_specimens
(Pathological samples)
Original: Pathologic features#were reviewed using#Page's criteria and correlated with excision specimens
#2005
low Confidence
Subject:
pathologic_features
(Pathological characteristics)
→
were_reviewed_using
→
Object:
Page_criteria
(Diagnostic criteria)
Original: Pathologic features#were reviewed using#Page's criteria and correlated with excision specimens
#2004
low Confidence
Subject:
patients_with_lobular_carcinoma_in_situ
(Patient population)
→
underwent
→
Object:
breast_excisions
(Surgical procedures)
Original: Patients with atypical ductal hyperplasia or lobular carcinoma in situ#underwent#breast excisions
#2003
low Confidence
Subject:
patients_with_atypical_ductal_hyperplasia
(Patient population)
→
underwent
→
Object:
breast_excisions
(Surgical procedures)
Original: Patients with atypical ductal hyperplasia or lobular carcinoma in situ#underwent#breast excisions
#1999
low Confidence
Subject:
differential_diagnosis_of_thyroid_GCT
(Diagnostic Process)
→
includes
→
Object:
follicular_cells
(Cell Type)
Original: differential diagnosis of thyroid GCT#includes#Hurthle cells/ macrophages/ follicular cells/ and cells of black thyroid syndrome
#1998
low Confidence
Subject:
differential_diagnosis_of_thyroid_GCT
(Diagnostic Process)
→
includes
→
Object:
macrophages
(Immune cells)
Original: differential diagnosis of thyroid GCT#includes#Hurthle cells/ macrophages/ follicular cells/ and cells of black thyroid syndrome
#1997
low Confidence
Subject:
differential_diagnosis_of_thyroid_GCT
(Diagnostic Process)
→
includes
→
Object:
Hurthle_cells
(Cell Type)
Original: differential diagnosis of thyroid GCT#includes#Hurthle cells/ macrophages/ follicular cells/ and cells of black thyroid syndrome
#1906
low Confidence
Subject:
CK7
(Keratin)
→
could_be_focally_stained
→
Object:
CK7_focal_staining
(Immunohistochemical markers)
Original: CD10 or CK7#could be#focally stained in some cases
#1905
low Confidence
Subject:
CD10
(Protease)
→
could_be_focally_stained
→
Object:
CD10_focal_staining
(Immunohistochemical markers)
Original: CD10 or CK7#could be#focally stained in some cases
#1896
low Confidence
Subject:
tumors_with_histologic_features
(Tumor)
→
should_not_be_included_under
→
Object:
typical_PLGA
(Adenomatous tumor)
Original: Tumors with these histologic features#should not be included under#typical PLGA
#1795
low Confidence
Subject:
distinguishing
(Diagnostic Process)
→
is
→
Object:
diagnostic_challenge
(Difficulties in diagnosis)
Original: Distinguishing among reactive mesothelial cells/ malignant mesothelioma/ and adenocarcinoma#is#a diagnostic challenge
#1587
low Confidence
Subject:
differentiation_of_tumor_tissue
(Tumor differentiation characteristics)
→
is_indicated_by
→
Object:
visible_nucleolus
(Nuclear morphology)
Original: Differentiation of tumor tissue#was indicated by#increasing cellular cytoplasm and cytoplasmic process development/ nuclear enlargement and visible nucleolus
#1586
low Confidence
Subject:
differentiation_of_tumor_tissue
(Tumor differentiation characteristics)
→
is_indicated_by
→
Object:
nuclear_enlargement
(Nuclear morphology)
Original: Differentiation of tumor tissue#was indicated by#increasing cellular cytoplasm and cytoplasmic process development/ nuclear enlargement and visible nucleolus
#1585
low Confidence
Subject:
differentiation_of_tumor_tissue
(Tumor differentiation characteristics)
→
is_indicated_by
→
Object:
cytoplasmic_process_development
(Cell morphology)
Original: Differentiation of tumor tissue#was indicated by#increasing cellular cytoplasm and cytoplasmic process development/ nuclear enlargement and visible nucleolus
#1584
low Confidence
Subject:
differentiation_of_tumor_tissue
(Tumor differentiation characteristics)
→
is_indicated_by
→
Object:
increasing_cellular_cytoplasm
(Cell morphology)
Original: Differentiation of tumor tissue#was indicated by#increasing cellular cytoplasm and cytoplasmic process development/ nuclear enlargement and visible nucleolus
#1515
low Confidence
Subject:
border_between_tub0_and_adenomatous_areas
(Pathological border)
→
could_not_be_identified_within
→
Object:
neoplastic_lesion
(Tumor lesions)
Original: Border between tub 0 and adenomatous areas#could not be identified#within neoplastic lesion
#1464
low Confidence
Subject:
colonic_primary
(Tumor diseases)
→
discovered_during
→
Object:
emergency_laparotomy
(Diagnostic and treatment procedures)
Original: Colonic primary#was discovered during#emergency laparotomy
#1383
low Confidence
Subject:
aspirate
(Cell samples)
→
is_characterized_by
→
Object:
epithelial_cells
(cell)
Original: The aspirate#is characterized by#flat cohesive sheets of epithelial cells with granular oncocytic cytoplasm and enlarged round nuclei
#1329
low Confidence
Subject:
FNAC_diagnosis
(Cytological diagnosis)
→
is_reported_in
→
Object:
rare_cases_of_spermatocytic_seminoma
(Case)
Original: FNAC diagnosis#is reported in#rare cases of spermatocytic seminoma
#1312
low Confidence
Subject:
female_18_years
(Patient characteristics)
→
was_admitted_with
→
Object:
weight_loss
(symptom)
Original: An 18 years female#was admitted with#right-sided chest pain/ dry cough/ low-grade fever/ and weight loss for last 1 month
#1311
low Confidence
Subject:
female_18_years
(Patient characteristics)
→
was_admitted_with
→
Object:
low-grade_fever
(symptom)
Original: An 18 years female#was admitted with#right-sided chest pain/ dry cough/ low-grade fever/ and weight loss for last 1 month
#1310
low Confidence
Subject:
female_18_years
(Patient characteristics)
→
was_admitted_with
→
Object:
dry_cough
(symptom)
Original: An 18 years female#was admitted with#right-sided chest pain/ dry cough/ low-grade fever/ and weight loss for last 1 month
#1309
low Confidence
Subject:
female_18_years
(Patient characteristics)
→
was_admitted_with
→
Object:
right-sided_chest_pain
(symptom)
Original: An 18 years female#was admitted with#right-sided chest pain/ dry cough/ low-grade fever/ and weight loss for last 1 month
#1266
low Confidence
Subject:
woman
(patient)
→
presents_with
→
Object:
weight_loss
(symptom)
Original: woman#presents with#upper abdominal pain and weight loss
#1265
low Confidence
Subject:
woman
(patient)
→
presents_with
→
Object:
upper_abdominal_pain
(symptom)
Original: woman#presents with#upper abdominal pain and weight loss
#1263
low Confidence
Subject:
figures
(Quantitative indicators)
→
may_be_used_to_evaluate
→
Object:
tumor_cell_differentiation
(Cell differentiation)
Original: Figures#may be used to evaluate#tumor cell differentiation in individual patients
#1245
low Confidence
Subject:
neoplastic_lesion
(Tumor lesions)
→
was_palpated_in
→
Object:
right_papilla
(Anatomical location)
Original: a neoplastic lesion#was palpated#in the right papilla
#1238
low Confidence
Subject:
Miniature_Horse
(Animal individuals)
→
was_diagnosed_with
→
Object:
malignant_abdominal_neoplasm
(Neoplastic diseases)
Original: Miniature Horse#was diagnosed with#a malignant abdominal neoplasm
#1220
low Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
included
→
Object:
granulocytic_sarcoma
(Disease phenotype)
Original: Differential diagnoses#included#inflammatory lesions/ small cell carcinoma/ endometrial stromal sarcoma/ granulocytic sarcoma
#1219
low Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
included
→
Object:
endometrial_stromal_sarcoma
(Disease phenotype)
Original: Differential diagnoses#included#inflammatory lesions/ small cell carcinoma/ endometrial stromal sarcoma/ granulocytic sarcoma
#1218
low Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
included
→
Object:
small_cell_carcinoma
(Disease phenotype)
Original: Differential diagnoses#included#inflammatory lesions/ small cell carcinoma/ endometrial stromal sarcoma/ granulocytic sarcoma
#1217
low Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
included
→
Object:
inflammatory_lesions
(Disease phenotype)
Original: Differential diagnoses#included#inflammatory lesions/ small cell carcinoma/ endometrial stromal sarcoma/ granulocytic sarcoma
#1033
low Confidence
Subject:
pathological_diagnosis
(Pathological diagnosis)
→
shares_characteristics_with
→
Object:
solid_tumor_in_the_cyst
(Tumor tissue)
Original: Pathological diagnosis#shared#characteristics with the solid tumor in the cyst
#1020
low Confidence
Subject:
prominent_nucleoli
(Nuclear morphology)
→
may_be
→
Object:
underdiagnosed
(Missed diagnosis)
Original: Prominent nucleoli in IM cells#may be#underdiagnosed
#998
low Confidence
Subject:
prominent_nucleoli
(Nuclear characteristics)
→
did_not_improve
→
Object:
discriminatory_power_of_binary_discriminant_model
(Diagnostic model performance)
Original: adding vacuolization/ anisocytosis/ prominent nucleoli/ and multinucleation#did not improve#discriminatory power of binary discriminant model
#841
low Confidence
Subject:
Understanding_IVLBCL
(Knowledge Acquisition)
→
would_help
→
Object:
pathologists_avoid_misdiagnoses
(Clinical diagnosis)
Original: Understanding IVLBCL#would help#pathologists avoid misdiagnoses
#758
low Confidence
Subject:
cytological_features
(Cytological characteristics)
→
distinguished_reliably
→
Object:
lobular_carcinoma
(Tumor type)
Original: No cytological features#distinguished reliably#ductal from lobular carcinoma
#757
low Confidence
Subject:
cytological_features
(Cytological characteristics)
→
distinguished_reliably
→
Object:
ductal_carcinoma
(Tumor type)
Original: No cytological features#distinguished reliably#ductal from lobular carcinoma
#617
low Confidence
Subject:
endometrial_curettage
(Diagnostic techniques)
→
performed
→
Object:
two_times_in_two_months
(Treatment process)
Original: two suction endometrial curettages#were performed#in a period of two months
#615
low Confidence
Subject:
thyroid_GCT
(Tumor diseases)
→
has_been_reported_in
→
Object:
four_cases
(Number of cases)
Original: thyroid GCT#has been reported in#four cases
#614
low Confidence
Subject:
Primary_intestinal_cytotoxic_natural_killer-like_T-cell_lymphoma
(Rare tumor subtypes)
→
is
→
Object:
rare_entity
(Disease phenotype)
Original: Primary intestinal cytotoxic natural killer-like T-cell lymphoma#is#a rare entity
#597
low Confidence
Subject:
endometrial_aspiration
(Diagnostic Methods)
→
was_performed_on
→
Object:
patient
(patient)
Original: Cervical smear and endometrial aspiration#were performed#on the patient
#596
low Confidence
Subject:
cervical_smear
(Diagnostic Methods)
→
was_performed_on
→
Object:
patient
(patient)
Original: Cervical smear and endometrial aspiration#were performed#on the patient
#495
low Confidence
Subject:
fine-needle_aspiration_biopsy
(Clinical testing technology)
→
describes
→
Object:
cytological_findings
(Cytological characteristics)
Original: We#describe#the cytological findings of a fine-needle aspiration biopsy (FNAB) from the right medial knee of a 45-yr-old woman
#487
low Confidence
Subject:
differential_diagnosis
(Diagnostic Process)
→
includes
→
Object:
neoplasms_with_clear_cells
(Tumor Entities)
Original: differential diagnosis#includes#neoplasms with clear cells that can involve the adrenal gland
#471
low Confidence
Subject:
cytologic_diagnosis
(Diagnostic Methods)
→
should_be_made
→
Object:
carefully
(Diagnostic recommendations)
Original: Cytologic diagnosis of metastatic cervical adenocarcinoma#should be made#carefully
#383
low Confidence
Subject:
44-year-old_man
(Patient characteristics)
→
had
→
Object:
myelolipoma
(Myelolipoma)
Original: A 44-year-old man#had#seminoma and myelolipoma in an undescended testis
#382
low Confidence
Subject:
44-year-old_man
(Patient characteristics)
→
had
→
Object:
seminoma
(Testicular tumors)
Original: A 44-year-old man#had#seminoma and myelolipoma in an undescended testis
#378
low Confidence
Subject:
nuclei
(Nucleus)
→
occupy
→
Object:
about_one_third_of_the_cell
(Cell structure ratio)
Original: nuclei#occupy#about one third of the cell
#377
low Confidence
Subject:
cytologic_appearance
(Cell morphology)
→
includes
→
Object:
slender_elongate_columnar_cells_arranged_in_clusters
(Morphological characteristics)
Original: Cytologic appearance#included#slender/ elongate columnar cells arranged in clusters
#376
low Confidence
Subject:
tumor_masses
(Tumor tissue)
→
are_composed_of
→
Object:
anisocytotic_cells_with_round_to_oval_nuclei_and_nucleoli
(Morphological characteristics)
Original: Masses#were composed of#anisocytotic cells with round to oval nuclei and nucleoli
#375
low Confidence
Subject:
neoplastic_cells
(Tumor cells)
→
have
→
Object:
hyperchromatic_nuclei_with_prominent_nucleoli
(Morphological characteristics)
Original: Neoplastic cells#had#hyperchromatic nuclei with prominent nucleoli
#374
low Confidence
Subject:
tumor_cells
(Tumor cells)
→
show
→
Object:
pleomorphic_features_with_large_nucleoli_and_irregular_thickening_membrane
(Morphological characteristics)
Original: Cells#showed#pleomorphic features with large nucleoli and irregular thickening membrane
#373
low Confidence
Subject:
tumor_mass
(Tumor tissue)
→
consists_of
→
Object:
large_polygonal_cells_with_high_nucleus_to_cytoplasm_ratio_and_prominent_nucleoli
(Morphological characteristics)
Original: Mass#consisted of#large polygonal cells with high nucleus-to-cytoplasm ratio and prominent nucleoli
#372
low Confidence
Subject:
tumor_cells
(Tumor cells)
→
show
→
Object:
primitive_round_to_oval_cell_morphology_with_prominent_nucleoli
(Morphological characteristics)
Original: Tumors#showed#primitive/ round to oval cell morphology with prominent nucleoli
#371
low Confidence
Subject:
lesion
(Tumor tissue)
→
is_composed_of
→
Object:
cords_of_large_polygonal_cells
(Cell morphology)
Original: Lesions#were composed of#sheets/ nests/ and cords of large polygonal cells
#370
low Confidence
Subject:
lesion
(Tumor tissue)
→
is_composed_of
→
Object:
nests_of_large_polygonal_cells
(Cell morphology)
Original: Lesions#were composed of#sheets/ nests/ and cords of large polygonal cells
#369
low Confidence
Subject:
lesion
(Tumor tissue)
→
is_composed_of
→
Object:
sheets_of_large_polygonal_cells
(Cell morphology)
Original: Lesions#were composed of#sheets/ nests/ and cords of large polygonal cells
#345
low Confidence
Subject:
no_features
(Morphological characteristics)
→
differentiated
→
Object:
grade_1_SCA
(Tumor type)
Original: No features#differentiated#SBT from grade 1 SCA
#344
low Confidence
Subject:
no_features
(Morphological characteristics)
→
differentiated
→
Object:
SBT
(Tumor type)
Original: No features#differentiated#SBT from grade 1 SCA
#287
low Confidence
Subject:
Skin_infiltration
(Clinical manifestations)
→
precedents
→
Object:
bone_marrow_evidence_of_AML
(Clinical testing)
Original: Skin infiltration#preceded#blood or bone marrow evidence of AML
#286
low Confidence
Subject:
Skin_infiltration
(Clinical manifestations)
→
precedents
→
Object:
blood_evidence_of_AML
(Clinical testing)
Original: Skin infiltration#preceded#blood or bone marrow evidence of AML
#280
low Confidence
Subject:
Cases
(Case)
→
show
→
Object:
intranuclear_cytoplasmic_inclusions
(Cell morphology)
Original: Cases#show#plasmacytoid cells/ bi/multinucleation/ and intranuclear cytoplasmic inclusions
#279
low Confidence
Subject:
Cases
(Case)
→
show
→
Object:
bi/multinucleation
(Cell morphology)
Original: Cases#show#plasmacytoid cells/ bi/multinucleation/ and intranuclear cytoplasmic inclusions
#278
low Confidence
Subject:
Cases
(Case)
→
show
→
Object:
plasmacytoid_cells
(Cell Type)
Original: Cases#show#plasmacytoid cells/ bi/multinucleation/ and intranuclear cytoplasmic inclusions
#210
low Confidence
Subject:
tumor
(Malignant tumors)
→
showed_no
→
Object:
prominent_nucleoli
(Cell nucleolus characteristics)
Original: tumor#showed no#prominent nucleoli
#192
low Confidence
Subject:
specimens_from_various_carcinoma_types
(Tumor specimens)
→
are_reviewed
→
Object:
carcinoma_types
(Tumor type)
Original: Specimens#from various carcinoma types#are reviewed
#191
low Confidence
Subject:
positive_cytology_cases
(Cytological diagnosis results)
→
are_reviewed_for
→
Object:
cytologic_features
(Cytological characteristics)
Original: Positive cytology cases#are reviewed for#cytologic features
#190
low Confidence
Subject:
cytological_variables
(Cytological characteristics)
→
are_reviewed_for
→
Object:
patients_with_suspicious_nodules
(patient)
Original: Cytological variables#are retrospectively reviewed for#patients with suspicious nodules
#111
low Confidence
Subject:
cytologic_features
(Cell morphology)
→
have_been_reported_in
→
Object:
disease
(disease)
Original: There#have been#a few reports of distant metastasis and cytologic features of the disease
#77
low Confidence
Subject:
immunohistochemical_study_of_Cyt
(Molecular testing)
→
revealed
→
Object:
not_helpful_in_differential_diagnosis_of_LM_from_LS
(Diagnosis conclusion)
Original: Immunohistochemical studies of Vim/ Des/ S100/ FN/ and Cyt#revealed#none of them was very helpful in the differential diagnosis of LM from LS
#76
low Confidence
Subject:
immunohistochemical_study_of_FN
(Molecular testing)
→
revealed
→
Object:
not_helpful_in_differential_diagnosis_of_LM_from_LS
(Diagnosis conclusion)
Original: Immunohistochemical studies of Vim/ Des/ S100/ FN/ and Cyt#revealed#none of them was very helpful in the differential diagnosis of LM from LS
#75
low Confidence
Subject:
immunohistochemical_study_of_S100
(Molecular testing)
→
revealed
→
Object:
not_helpful_in_differential_diagnosis_of_LM_from_LS
(Diagnosis conclusion)
Original: Immunohistochemical studies of Vim/ Des/ S100/ FN/ and Cyt#revealed#none of them was very helpful in the differential diagnosis of LM from LS
#74
low Confidence
Subject:
immunohistochemical_study_of_Des
(Molecular testing)
→
revealed
→
Object:
not_helpful_in_differential_diagnosis_of_LM_from_LS
(Diagnosis conclusion)
Original: Immunohistochemical studies of Vim/ Des/ S100/ FN/ and Cyt#revealed#none of them was very helpful in the differential diagnosis of LM from LS
#73
low Confidence
Subject:
immunohistochemical_study_of_Vim
(Molecular testing)
→
revealed
→
Object:
not_helpful_in_differential_diagnosis_of_LM_from_LS
(Diagnosis conclusion)
Original: Immunohistochemical studies of Vim/ Des/ S100/ FN/ and Cyt#revealed#none of them was very helpful in the differential diagnosis of LM from LS
#16
low Confidence
Subject:
retroperitoneal_biopsy
(Biopsy)
→
was_performed_on
→
Object:
patient
(patient)
Original: An orchidectomy and retroperitoneal biopsy#were performed#on the patient