Triple #12037
middle ConfidenceKnowledge triple
5-fluorouracil
Chemotherapy drugs
Level 11
→
induce
Positive regulatory relationship
→
changes_in_nuclear_AgNORs_pattern
Nucleolus-related structural changes
Level 4
Original triple： RNA inhibitors and 5-fluorouracil#induce#changes in nuclear AgNORs pattern in human breast cancer cells
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | In vitro assays/combination RNA inhibitors |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Response to treatment |
Other Info
| PMID: | 10381135 ↗ |
| Knowledge Particle: | KP2 |
| Value Leadboard: | 5 |
| Cell Type: | MCF-7/ HBC-4 |
| Disease: | Breast cancer |
| Treatment: | 5-fluorouracil |