Triple #12188
middle ConfidenceKnowledge triple
NPM1
Protein coding genes
Level 1
→
mutation
Gene mutation relationship
→
tryptophan_disruption
Abnormal protein structure
Level 2
Original triple： NPM1 mutations#create#a nuclear export signal and disrupt tryptophans
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | not_specified |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Pathogenesis |
Other Info
| PMID: | 19005479 ↗ |
| Knowledge Particle: | KP3 |
| Value Leadboard: | 6 |
| Gene Symbol: | NPM1 |
| Disease: | Acute myeloid leukemia |