Triple #12338
middle ConfidenceKnowledge triple
BRCA1
Tumor suppressor genes
Level 1
→
plays_role_in
Functional relationship
→
nucleolus
Cellular substructure
Level 6
Original triple： Tumor suppressors and proto-oncogenes#play#a direct role in the nucleolus and interact with RNA polymerase I machinery
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | not_specified |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | not_specified |
Other Info
| PMID: | 28846478 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | TP53/RB1/PTEN/PICT1/BRCA1/MYC/NPM1 |
| Disease: | Cancer |
| Pathway: | RNA polymerase I |