Triple #12364
middle ConfidenceKnowledge triple
ribosomal_stress
Cellular stress
Level 6
→
activates
Positive regulatory relationship
→
MDM2
protein
Level 2
Original triple： Acr#induces#ribosomal stress leading to MDM2 activation and RPL11-MDM2 binding
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | not_specified |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | not_specified |
Other Info
| PMID: | 27741518 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | MDM2/RPL11 |
| Treatment: | Acr |