Triple #12415
middle ConfidenceKnowledge triple
DNMT3A
DNA methyltransferase
Level 2
→
knockdown_enhances
Negative regulatory relationship
→
rDNA_transcription
Transcription process
Level 3
Original triple： Knockdown of DNMT3A#enhanced#rDNA transcription in NPM1-depleted U1242MG cells
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | NPM1_depleted_U1242MG_cells |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | not_specified |
Other Info
| PMID: | 25349213 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | DNMT3A/NPM1 |
| Cell Type: | U1242MG cells |