Triple #12418
middle ConfidenceKnowledge triple
MDM2
Ubiquitin ligase
Level 2
→
acts_as
Functional relationship
→
tumor_suppressor
Tumor suppressor function
Level 10
Original triple： p14ARF/ARF#acts as#a tumor suppressor through a p53/MDM2-dependent pathway
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | p53_pathway |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Cancer Prevention |
Other Info
| PMID: | 27323397 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | CDKN2A/TP53/MDM2 |
| Disease: | Cancer |