Triple #12449

middle Confidence

Knowledge triple

Roscovitine

Small molecule drugs

Level 11

induces

Positive regulatory relationship

nucleolar_unravelling

Cellular substructure phenotype

Level 2

Original triple: Roscovitine and olomoucine#induce#nuclear accumulation of wt p53 and nucleolar unravelling

Evidence and Confidence

Confidence: middle
Evidence Strength: experiment
Condition Dependency: not_specified
Fact or Inference: Fact

Clinical Relevance

Clinical Relevance: not_specified

Other Info

PMID: 11593402
Knowledge Particle: KP4
Value Leadboard: 7
Gene Symbol: CDK2/TP53
Disease: Breast tumor
Treatment: Roscovitine/Olomoucine