Triple #12483

middle Confidence

Knowledge triple

RPL11

Ribosomal proteins

Level 2

knockdown_abrogates

Negative regulatory relationship

NS_depletion_induced_p53_activation

Signaling pathway events

Level 5

Original triple: Knockdown of L5 or L11#abrogates#NS depletion-induced p53 activation and cell cycle arrest

Evidence and Confidence

Confidence: middle
Evidence Strength: experiment
Condition Dependency: not_specified
Fact or Inference: Fact

Clinical Relevance

Clinical Relevance: Cell cycle regulation

Other Info

PMID: 18426907
Knowledge Particle: KP4
Value Leadboard: 7
Gene Symbol: RPL5/RPL11/TP53