Triple #12486

middle Confidence

Knowledge triple

CDKN1A

Cell cycle protein inhibitors

Level 2

accumulation_leads_to

causation

cell_cycle_arrest

Cellular Processes

Level 6

Original triple: p53 induction#leads to#lineage-specific p21 accumulation and cell cycle arrest in erythroid progenitor cells

Evidence and Confidence

Confidence: middle
Evidence Strength: experiment
Condition Dependency: erythroid_progenitor_cells
Fact or Inference: Fact

Clinical Relevance

Clinical Relevance: Cell cycle regulation

Other Info

PMID: 21068437
Knowledge Particle: KP4
Value Leadboard: 7
Gene Symbol: TP53/CDKN1A