Triple #16831

middle Confidence

Knowledge triple

tumor_suppressors

Tumor suppressor proteins

Level 2

interfere_with

Negative regulatory relationship

rRNA_synthesis

rRNA synthesis

Level 4

Original triple: Oncogenic proteins and tumor suppressors#target#RNA polymerase I and interfere with rRNA synthesis

Evidence and Confidence

Confidence: middle
Evidence Strength: experiment
Condition Dependency: cancer_context
Fact or Inference: Fact

Clinical Relevance

Clinical Relevance: Tumorigenesis

Other Info

PMID: 18490923
Knowledge Particle: KP3
Value Leadboard: 6
Disease: Cancer