Triple #16917
middle ConfidenceKnowledge triple
PAX2
Transcription Factors
Level 2
→
inhibits
Negative regulatory relationship
→
migratory_capacity_of_melanoma_cells
Cell migration ability
Level 6
Original triple： PAX2 downregulation#inhibits#anchorage-independent cell growth/ migratory/ and invasive capacity of melanoma cells
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | PAX2_downregulation |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Tumor metastasis mechanism |
Other Info
| PMID: | 21876729 ↗ |
| Knowledge Particle: | KP3 |
| Value Leadboard: | 6 |
| Gene Symbol: | PAX2 |
| Disease: | Melanoma |