Triple #17030
middle ConfidenceKnowledge triple
MDM2
E3 ubiquitin ligase
Level 2
→
upregulates
Positive regulatory relationship
→
p53
Tumor suppressor proteins
Level 2
Original triple： NS1 expressed cells#showed#significant association of ribosomal proteins with MDM2 and p53 accumulation
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | NS1_expressed_cells |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | not_specified |
Other Info
| PMID: | 29259342 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | NS1/MDM2/TP53 |