Triple #17032
middle ConfidenceKnowledge triple
EAPB0503
Small molecule drugs
Level 11
→
induces
Positive regulatory relationship
→
proteasome-mediated_degradation_of_NPM1c
Protein degradation phenotype
Level 2
Original triple： EAPB0503#induces#proteasome-mediated degradation of NPM1c
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | not_specified |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Treatment related |
Other Info
| PMID: | 28055106 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | NPM1 |
| Disease: | AML |
| Treatment: | EAPB0503 |