Triple #17033

middle Confidence

Knowledge triple

EAPB0503

Small molecule drugs

Level 11

restores

Positive regulatory relationship

wt-NPM1_nucleolar_localization

Protein localization phenotype

Level 2

Original triple: EAPB0503#restores#wt-NPM1 nucleolar localization in NPM1c AML cells

Evidence and Confidence

Confidence: middle
Evidence Strength: experiment
Condition Dependency: NPM1c_AML_cells
Fact or Inference: Fact

Clinical Relevance

Clinical Relevance: Treatment related

Other Info

PMID: 28055106
Knowledge Particle: KP4
Value Leadboard: 7
Gene Symbol: NPM1
Disease: AML
Treatment: EAPB0503