Triple #17063
middle ConfidenceKnowledge triple
DKC1
Ribosome biogenesis-related enzymes
Level 2
→
silencing_reduces
Negative regulatory relationship
→
telomerase_activity
Enzyme activity
Level 2
Original triple： Dyskerin gene silencing#reduces#telomerase activity and rRNA pseudo-uridylation in MCF-7 cells
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | MCF-7 cells |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Tumor proliferation mechanism |
Other Info
| PMID: | 16841302 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | DKC1 |
| Cell Type: | MCF-7 cells |
| Disease: | Breast cancer |