Triple #17066
middle ConfidenceKnowledge triple
TP53
Tumor suppressor proteins
Level 2
→
induction_leads_to
causation
→
CDKN1A_accumulation
Cell cycle protein inhibitors
Level 2
Original triple： p53 induction#leads to#lineage-specific p21 accumulation and cell cycle arrest in erythroid progenitor cells
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | erythroid_progenitor_cells |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Cell cycle regulation |
Other Info
| PMID: | 21068437 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | TP53/CDKN1A |