Triple #17075
middle ConfidenceKnowledge triple
DHX33_K94R_mutant
DEAD/DEAH-box helicase mutants
Level 2
→
inhibits
Negative regulatory relationship
→
endogenous_rRNA_synthesis
rRNA synthesis
Level 4
Original triple： NTPase-defective DHX33 mutant (K94R)#inhibited#endogenous rRNA synthesis
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | In vitro experiments |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Transcriptional regulation |
Other Info
| PMID: | 21930779 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | DHX33 |
| Pathway: | RNA polymerase I |