Triple #17121
middle ConfidenceKnowledge triple
CDKN1B
protein
Level 2
→
allows
Functional relationship
→
tumor_cell_bypass_of_BRAF_induced_senescence
Escape from cellular senescence
Level 6
Original triple： Pro-oncogenic activities of CDKI (p27 and p57)#allow#tumor cells to bypass BRAF-induced senescence
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | BRAF signaling activation |
| Fact or Inference: | Inference |
Clinical Relevance
| Clinical Relevance: | Tumorigenesis |
Other Info
| PMID: | 22878367 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | CDKN1B/CDKN1C |
| Disease: | Tumor |