Triple #17220
middle ConfidenceKnowledge triple
Doxorubicin
Chemotherapy drugs
Level 11
→
inhibits
Negative regulatory relationship
→
cell_growth
Cell proliferation
Level 6
Original triple： DOX#induces#nucleophosmin translocation from the nucleolus to nucleoplasm and inhibits cell growth in a time- and dose-dependent manner
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | time_dose_dependent |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | treat |
Other Info
| PMID: | 1917161 ↗ |
| Knowledge Particle: | KP5 |
| Value Leadboard: | 1 |
| Gene Symbol: | NPM1 |
| Cell Type: | HL-60 cells |
| Treatment: | Doxorubicin |