Triple #18907

middle Confidence

Knowledge triple

celecoxib

Chemotherapy drugs

Level 11

decreases

Negative regulatory relationship

AgNORs_in_beta-catenin_accumulated_crypts

Nucleolar organizing region

Level 4

Original triple: Exposure to celecoxib#decreases#numbers of silver-stained nucleolar organizer regions (AgNORs) in beta-catenin-accumulated crypts

Evidence and Confidence

Confidence: middle
Evidence Strength: experiment
Condition Dependency: Drug exposure
Fact or Inference: Fact

Clinical Relevance

Clinical Relevance: Treatment related

Other Info

PMID: 11429049
Knowledge Particle: KP1
Value Leadboard: 9
Gene Symbol: CTNNB1
Treatment: Celecoxib