Triple #19145
middle ConfidenceKnowledge triple
APE1
DNA repair enzymes
Level 2
→
accumulates_in
Positioning relationship
→
NPM1c+_AML_cells
Tumor cells
Level 7
Original triple： Cytoplasmic accumulation of APE1#is associated with#NPM1c+ AML and other cancers
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | not_specified |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Pathogenic mechanism |
Other Info
| PMID: | 23831574 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | APE1/NPM1 |
| Disease: | Acute myeloid leukemia (AML)/cancers |