Triple #19162
middle ConfidenceKnowledge triple
Rpt4_knockdown
Protein expression downregulation
Level 2
→
inhibits
Negative regulatory relationship
→
growth_of_FLCN-deficient_renal_cancer_cells
Cell proliferation
Level 6
Original triple： Rpt4 knockdown#inhibits#growth of FLCN-deficient human renal cancer cells in mouse xenografts
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | Animal experiments |
| Condition Dependency: | Mouse transplant tumor |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Tumor growth inhibition |
Other Info
| PMID: | 23077212 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | Rpt4/FLCN |
| Disease: | Renal cancer |