Triple #19175
middle ConfidenceKnowledge triple
PGAM1
Phosphoglycerate mutase
Level 2
→
modulates
Regulatory Relationship
→
paclitaxel_resistance
Drug resistance
Level 12
Original triple： PGAM1-mediated pyruvic acid or lactic acid production#modulates#capabilities of ovarian cancer cell resistance to paclitaxel
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | pyruvic_acid_production |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Significance of drug resistance |
Other Info
| PMID: | 36224008 ↗ |
| Knowledge Particle: | KP5 |
| Value Leadboard: | 1 |
| Gene Symbol: | PGAM1 |
| Disease: | Ovarian cancer |
| Treatment: | Paclitaxel |