Triple #19188
middle ConfidenceKnowledge triple
PRIMA-1
Small molecule drugs
Level 0
→
restores
Positive regulatory relationship
→
transcriptional_transactivation_function_of_mutant_p53
Transcriptional regulation function
Level 3
Original triple： PRIMA-1#restores#transcriptional transactivation function to mutant p53
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | Experimental + Clinical |
| Condition Dependency: | Cell experiments |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Therapeutic significance |
Other Info
| PMID: | 16909106 ↗ |
| Knowledge Particle: | KP5 |
| Value Leadboard: | 1 |
| Gene Symbol: | TP53 |
| Treatment: | PRIMA-1 |