Triple #19224
middle ConfidenceKnowledge triple
PAX2
Transcription Factors
Level 2
→
downregulation_abrogated
Negative regulatory relationship
→
chemoresistance_in_melanoma_cells
Drug resistance
Level 12
Original triple： downregulation of PAX2#abrogated#chemoresistance in melanoma cells
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | Cisplatin treatment |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | treat |
Other Info
| PMID: | 21876729 ↗ |
| Knowledge Particle: | KP6 |
| Value Leadboard: | 3 |
| Gene Symbol: | PAX2 |
| Disease: | Melanoma |
| Treatment: | Cisplatin |