Triple #19872
middle ConfidenceKnowledge triple
Deguelin
Small molecule drugs
Level 11
→
downregulates
Negative regulatory relationship
→
NPM1_mutant_protein
Mutant protein
Level 2
Original triple： Deguelin#down-regulated#NPM1 mutant protein
Evidence and Confidence
| Confidence: | middle |
| Evidence Strength: | experiment |
| Condition Dependency: | In vitro/in vivo experiments |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Treatment Targeting |
Other Info
| PMID: | 25242579 ↗ |
| Knowledge Particle: | KP2 |
| Value Leadboard: | 5 |
| Gene Symbol: | NPM1 |
| Disease: | Leukemia |
| Treatment: | Deguelin |