Triple #20076

high Confidence

Knowledge triple

guanine_nucleotide_depletion

Metabolic status

Level 3

causes

causation

nucleolar_protein_translocation

Subcellular structural changes

Level 4

Original triple: Depletion of guanine nucleotides by MPA and AVN-944#causes#translocation of nucleolar proteins to the nucleoplasm

Evidence and Confidence

Confidence: high
Evidence Strength: Experimental + Clinical
Condition Dependency: Drug treatment
Fact or Inference: Fact

Clinical Relevance

Clinical Relevance: Treatment related

Other Info

PMID: 17462731
Knowledge Particle: KP4
Value Leadboard: 7
Treatment: MPA/AVN-944