Triple #20083
high ConfidenceKnowledge triple
p14ARF
Tumor suppressor proteins
Level 2
→
inhibits
Negative regulatory relationship
→
HDM2
Ubiquitin ligase
Level 2
Original triple： p14ARF#activates#p53 by binding and inhibiting HDM2
Evidence and Confidence
| Confidence: | high |
| Evidence Strength: | experiment |
| Condition Dependency: | not_specified |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | not_specified |
Other Info
| PMID: | 23375502 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | CDKN2A/TP53/MDM2 |