Triple #20085
high ConfidenceKnowledge triple
NPM1
Protein coding genes
Level 1
→
is_associated_with
Correlation
→
cytoplasmic_localization_in_AML
Abnormal molecular localization
Level 3
Original triple： One-third of acute myeloid leukemias (AMLs)#are associated with#aberrant localization of NPM1 to the cytoplasm (NPM1c+)
Evidence and Confidence
| Confidence: | high |
| Evidence Strength: | Clinical + Experimental |
| Condition Dependency: | not_specified |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Pathogenic mechanism |
Other Info
| PMID: | 23831574 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | NPM1 |
| Disease: | Acute myeloid leukemia (AML) |
| Pathway: | Cytoplasmic localization |