Triple #20365
high ConfidenceKnowledge triple
BMH-21
Small molecule drugs
Level 11
→
inhibits
Negative regulatory relationship
→
RNA_Polymerase_I
Enzymes
Level 2
Original triple： Pharmacologic inhibition of RNA polymerase I#attenuates#signal in prostate tissue slices
Evidence and Confidence
| Confidence: | high |
| Evidence Strength: | Experimental + Clinical |
| Condition Dependency: | prostate_tissue_slice |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Therapeutic significance |
Other Info
| PMID: | 28119429 ↗ |
| Knowledge Particle: | KP2 |
| Value Leadboard: | 5 |
| Cell Type: | Prostate tissue |
| Disease: | Prostate cancer |
| Treatment: | BMH-21/ actinomycin D |