Triple #20380

high Confidence

Knowledge triple

RNA_Polymerase_I_inhibitor

Small molecule inhibitors

Level 11

blocks

Negative regulatory relationship

ribosomal_DNA_transcription

Transcription process

Level 3

Original triple: Small molecule inhibitors of RNA Polymerase I#block#ribosomal DNA transcription

Evidence and Confidence

Confidence: high
Evidence Strength: Experimental + Clinical
Condition Dependency: not_specified
Fact or Inference: Fact

Clinical Relevance

Clinical Relevance: Treatment Mechanism

Other Info

PMID: 24389329
Knowledge Particle: KP3
Value Leadboard: 6
Gene Symbol: POLR1A
Disease: Cancer