Triple #20399
high ConfidenceKnowledge triple
NPM1
Protein coding genes
Level 1
→
leads_to
causation
→
aberrant_cytoplasmic_localization
Subcellular localization
Level 2
Original triple： Mutations in NPM1#lead to#aberrant cytoplasmic localization in AML
Evidence and Confidence
| Confidence: | high |
| Evidence Strength: | Clinical + Experimental |
| Condition Dependency: | not_specified |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Pathogenesis |
Other Info
| PMID: | 18625840 ↗ |
| Knowledge Particle: | KP3 |
| Value Leadboard: | 6 |
| Gene Symbol: | NPM1 |
| Disease: | Acute myelogenous leukemia (AML) |
| Pathway: | NPM1 pathway |