Triple #20459
high ConfidenceKnowledge triple
MG132
Proteasome inhibitors
Level 11
→
inhibits
Negative regulatory relationship
→
Survivin-deltaEx3_degradation
Protein degradation process
Level 3
Original triple： Proteasome inhibitors MG132 or ALLN#inhibit#degradation of Survivin-deltaEx3
Evidence and Confidence
| Confidence: | high |
| Evidence Strength: | Experimental + Clinical |
| Condition Dependency: | not_specified |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Therapeutic significance |
Other Info
| PMID: | 15735764 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | BIRC5 |
| Treatment: | MG132/ALLN |