Triple #20460

high Confidence

Knowledge triple

ALLN

Proteasome inhibitors

Level 11

inhibits

Negative regulatory relationship

Survivin-deltaEx3_degradation

Protein degradation process

Level 3

Original triple: Proteasome inhibitors MG132 or ALLN#inhibit#degradation of Survivin-deltaEx3

Evidence and Confidence

Confidence: high
Evidence Strength: Experimental + Clinical
Condition Dependency: not_specified
Fact or Inference: Fact

Clinical Relevance

Clinical Relevance: Therapeutic significance

Other Info

PMID: 15735764
Knowledge Particle: KP4
Value Leadboard: 7
Gene Symbol: BIRC5
Treatment: MG132/ALLN