Triple #20529

high Confidence

Knowledge triple

GSK2118436

Small molecule drugs

Level 11

affects

Regulatory Relationship

CDKN1B_expression

Protein expression

Level 2

Original triple: GSK2118436#affects#expression patterns of CDKI (p16/ p21/ p27/ p57)

Evidence and Confidence

Confidence: high
Evidence Strength: experiment
Condition Dependency: Drug treatment
Fact or Inference: Fact

Clinical Relevance

Clinical Relevance: Response to treatment

Other Info

PMID: 22878367
Knowledge Particle: KP4
Value Leadboard: 7
Gene Symbol: CDKN2A/CDKN1A/CDKN1B/CDKN1C
Disease: Melanoma
Treatment: GSK2118436