Triple #20905
high ConfidenceKnowledge triple
MYCN amplification
Gene amplification
Level 1
→
inhibits
Negative regulatory relationship
→
cellular differentiation
Cell differentiation
Level 6
Original triple： MYCN amplification#prevents#cellular differentiation
Evidence and Confidence
| Confidence: | high |
| Evidence Strength: | Experimental + Clinical |
| Condition Dependency: | not_specified |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Pathogenesis |
Other Info
| PMID: | 21288077 ↗ |
| Knowledge Particle: | KP8 |
| Value Leadboard: | 8 |
| Gene Symbol: | MYCN |
| Disease: | Neuroblastoma |