Triple #21427

high Confidence

Knowledge triple

Bortezomib

Proteasome inhibitors

Level 11

interferes_with

Negative regulatory relationship

protein_biosynthesis_at_nucleolar_ribosome_biogenesis_stage

Molecular Process

Level 4

Original triple: bortezomib#interferes with#protein biosynthesis at nucleolar ribosome biogenesis stage

Evidence and Confidence

Confidence: high
Evidence Strength: Experimental + Clinical
Condition Dependency: not_specified
Fact or Inference: Fact

Clinical Relevance

Clinical Relevance: Treatment Mechanism

Other Info

PMID: 27567537
Knowledge Particle: KP5
Value Leadboard: 1
Treatment: Bortezomib