Triple #21564
high ConfidenceKnowledge triple
ribosome_biogenesis
Ribosome biogenesis
Level 4
→
disruption_kills
causation
→
tumor_cells
cancer cell
Level 7
Original triple： Disruption of ribosome biogenesis#kills#tumor cells via nucleolar function disruption
Evidence and Confidence
| Confidence: | high |
| Evidence Strength: | Experiment + drug intervention |
| Condition Dependency: | nucleolar_function_disruption |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | treat |
Other Info
| PMID: | 25464032 ↗ |
| Knowledge Particle: | KP3 |
| Value Leadboard: | 6 |
| Gene Symbol: | TP53 |
| Disease: | Tumor |
| Treatment: | CX-5461 |