Triple #21586

high Confidence

Knowledge triple

DCAF13

Ubiquitin ligase

Level 2

mediates

Regulatory Relationship

K63-linked_ubiquitination_of_POLR1A

Protein modification

Level 3

Original triple: DCAF13-mediated K63-linked ubiquitination of RNA polymerase I#promotes#uncontrolled proliferation in Breast Cancer

Evidence and Confidence

Confidence: high
Evidence Strength: experiment
Condition Dependency: Breast cancer cells
Fact or Inference: Fact

Clinical Relevance

Clinical Relevance: not_specified

Other Info

PMID: 39788980
Knowledge Particle: KP3
Value Leadboard: 6
Gene Symbol: DCAF13/POLR1A
Disease: Breast cancer