Triple #21587
high ConfidenceKnowledge triple
K63-linked_ubiquitination_of_POLR1A
Protein modification
Level 3
→
promotes
Positive regulatory relationship
→
uncontrolled_proliferation
Cell proliferation
Level 6
Original triple： DCAF13-mediated K63-linked ubiquitination of RNA polymerase I#promotes#uncontrolled proliferation in Breast Cancer
Evidence and Confidence
| Confidence: | high |
| Evidence Strength: | experiment |
| Condition Dependency: | Breast cancer cells |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | Tumor progression |
Other Info
| PMID: | 39788980 ↗ |
| Knowledge Particle: | KP3 |
| Value Leadboard: | 6 |
| Gene Symbol: | DCAF13/POLR1A |
| Disease: | Breast cancer |