Triple #21591
high ConfidenceKnowledge triple
rRNA_biogenesis
Molecular Process
Level 6
→
activates
Positive regulatory relationship
→
p53
Tumor suppressor proteins
Level 2
Original triple： Disruption of rRNA biogenesis#activates#p53 by release of ribosomal proteins from nucleoli
Evidence and Confidence
| Confidence: | high |
| Evidence Strength: | experiment |
| Condition Dependency: | ribosomal_protein_release |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | not_specified |
Other Info
| PMID: | 17110929 ↗ |
| Knowledge Particle: | KP3 |
| Value Leadboard: | 6 |
| Gene Symbol: | TP53/MDM2 |