Triple #21612
high ConfidenceKnowledge triple
H2AX
Histone variants
Level 2
→
is_upregulated_in
Positive regulatory relationship
→
irradiated_genome
Damaged genome
Level 1
Original triple： Increased levels of H2AX and 53BP1 proteins#were confirmed in#irradiated genome
Evidence and Confidence
| Confidence: | high |
| Evidence Strength: | Experimental + Clinical |
| Condition Dependency: | Radiation exposure |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | not_specified |
Other Info
| PMID: | 25369346 ↗ |
| Knowledge Particle: | KP4 |
| Value Leadboard: | 7 |
| Gene Symbol: | H2AX/TP53BP1 |