Triple #21653
high ConfidenceKnowledge triple
Cyclin_D1
Cell cycle proteins
Level 2
→
activates
Positive regulatory relationship
→
CDK4
Protein kinase
Level 2
Original triple： Cyclin D1#activates#cdk4 to produce retinoblastoma protein phosphorylation
Evidence and Confidence
| Confidence: | high |
| Evidence Strength: | experiment |
| Condition Dependency: | not_specified |
| Fact or Inference: | Inference |
Clinical Relevance
| Clinical Relevance: | Cell cycle regulation |
Other Info
| PMID: | 12834607 ↗ |
| Knowledge Particle: | KP5 |
| Value Leadboard: | 1 |
| Gene Symbol: | CCND1/CDK4 |
| Disease: | Retinoblastoma |