Triple #22004
high ConfidenceKnowledge triple
LATS_kinases
Protein kinase
Level 2
→
phosphorylation
Molecular modification
→
YAP
Transcription coactivator
Level 2
Original triple： activation of Hippo pathway#restricts#YAP nuclear entry via phosphorylation by Lats kinases
Evidence and Confidence
| Confidence: | high |
| Evidence Strength: | experiment |
| Condition Dependency: | Hippo pathway activation |
| Fact or Inference: | Fact |
Clinical Relevance
| Clinical Relevance: | not_specified |
Other Info
| PMID: | 25658431 ↗ |
| Knowledge Particle: | KP3 |
| Value Leadboard: | 6 |
| Gene Symbol: | YAP/LATS1/LATS2 |
| Pathway: | Hippo pathway |